hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-02372739/chunk_1/iprscan-20080502-02372739.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0424 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00621.11.fs RhoGEF domain 126.8 2.7e-37 1 PF00621.11.ls RhoGEF domain 128.6 1.6e-35 1 PF00169.19.fs PH domain 39.9 1.1e-11 1 PF00018.18.fs SH3 domain 41.2 1.8e-10 1 PF07653.7.fs Variant SH3 domain 37.3 4.2e-10 1 PF00169.19.ls PH domain 41.9 2e-09 1 PF00018.18.ls SH3 domain 38.4 2.2e-08 1 PF07653.7.ls Variant SH3 domain 37.6 3.8e-08 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00018.18.ls 1/1 62 116 .. 1 59 [] 38.4 2.2e-08 PF07653.7.ls 1/1 63 116 .. 1 69 [] 37.6 3.8e-08 PF07653.7.fs 1/1 75 116 .. 14 69 .] 37.3 4.2e-10 PF00018.18.fs 1/1 77 116 .. 16 59 .] 41.2 1.8e-10 PF00621.11.fs 1/1 158 337 .. 1 207 [] 126.8 2.7e-37 PF00621.11.ls 1/1 158 337 .. 1 207 [] 128.6 1.6e-35 PF00169.19.fs 1/1 370 476 .. 1 92 [] 39.9 1.1e-11 PF00169.19.ls 1/1 370 476 .. 1 92 [] 41.9 2e-09 Alignments of top-scoring domains: PF00018.18.ls: domain 1 of 1, from 62 to 116: score 38.4, E = 2.2e-08 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk + A D + + EL Fk GDvi+vl+ s+ +WW g+ + ++ KIAA0424 62 VSAEAVWDHVTMANRELAFKAGDVIKVLDASNK-DWWWGQID---DE 104 eGliPsNYVepv<-* eG++P+++V++ KIAA0424 105 EGWFPASFVRLW 116 PF07653.7.ls: domain 1 of 1, from 63 to 116: score 37.6, E = 3.8e-08 *->ygraiedyvaAtdknenleeeeLslkkGdvvkVidvggskdddgwwe + a+ d+v ++e L++k+Gdv+kV+ + ++ +ww+ KIAA0424 63 SAEAVWDHVT-MANRE------LAFKAGDVIKVL----DASNKDWWW 98 geslggGrrrRGlvPssaveel<-* g + ++ G++P+s+v+ + KIAA0424 99 GQI--DDEE--GWFPASFVRLW 116 PF07653.7.fs: domain 1 of 1, from 75 to 116: score 37.3, E = 4.2e-10 *->knenleeeeLslkkGdvvkVidvggskdddgwwegeslggGrrrRGl ++e L++k+Gdv+kV+ + ++ +ww+g + ++ G+ KIAA0424 75 NRE------LAFKAGDVIKVL----DASNKDWWWGQI--DDEE--GW 107 vPssaveel<-* +P+s+v+ + KIAA0424 108 FPASFVRLW 116 PF00018.18.fs: domain 1 of 1, from 77 to 116: score 41.2, E = 1.8e-10 *->ELsFkkGDvitvleksddpgWWkgrlkgtgGkeGliPsNYVepv<-* EL Fk GDvi+vl+ s+ +WW g+ + ++eG++P+++V++ KIAA0424 77 ELAFKAGDVIKVLDASNK-DWWWGQID---DEEGWFPASFVRLW 116 PF00621.11.fs: domain 1 of 1, from 158 to 337: score 126.8, E = 2.7e-37 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E++ TE+ Y+++L ++ +y+k+ r+ + + ++ ++++ iF KIAA0424 158 VINEIMSTERHYIKHLKDICEGYLKQCRK--RRD--MFSDEQLKVIF 200 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+f+ F + Le+ +p+ + +G++Fle+ KIAA0424 201 GNIEDIYRFQMGFVR-DLEKQYNND----------DPHLSEIGPCFLEH- 238 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd + + +Y eYc+n+ +A l+kl ++ F+e + +++ + KIAA0424 239 QDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMID----- 283 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda ++ +Ll Pvq i++YpL L eLLk+t d+s++ +al+ KIAA0424 284 ----IAIDGFLLTPVQKICKYPLQLAELLKYTAQ--DHSDYRYVAAALAV 327 lqdlaksiNe<-* ++++ ++iNe KIAA0424 328 MRNVTQQINE 337 PF00621.11.ls: domain 1 of 1, from 158 to 337: score 128.6, E = 1.6e-35 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E++ TE+ Y+++L ++ +y+k+ r+ + + ++ ++++ iF KIAA0424 158 VINEIMSTERHYIKHLKDICEGYLKQCRK--RRD--MFSDEQLKVIF 200 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+f+ F + Le+ +p+ + +G++Fle+ KIAA0424 201 GNIEDIYRFQMGFVR-DLEKQYNND----------DPHLSEIGPCFLEH- 238 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd + + +Y eYc+n+ +A l+kl ++ F+e + +++ + KIAA0424 239 QDGFWIYSEYCNNHLDACMELSKLMKDSRYQHFFEACRLLQQMID----- 283 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda ++ +Ll Pvq i++YpL L eLLk+t d+s++ +al+ KIAA0424 284 ----IAIDGFLLTPVQKICKYPLQLAELLKYTAQ--DHSDYRYVAAALAV 327 lqdlaksiNe<-* ++++ ++iNe KIAA0424 328 MRNVTQQINE 337 PF00169.19.fs: domain 1 of 1, from 370 to 476: score 39.9, E = 1.1e-11 *->vikeGwLlkkg.gkkswkkRyfvLfddvLlyykdkk.....kkpkgs +i+ G++ + ++ ++R f+Lfd +++++k++ +++ +kg KIAA0424 370 LIYTGEMAWIYqPYGRNQQRVFFLFDHQMVLCKKDLirrdiLYYKGR 416 ipLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerke i++++++v++++d+++++ + kn+F++++++ +e +l++a+ ee+ + KIAA0424 417 IDMDKYEVVDIEDGrdddfnvSMKNAFKLHNkETeEIHLFFAKKLEEKIR 466 Wvkaiqsair<-* W++a+++ + KIAA0424 467 WLRAFREERK 476 PF00169.19.ls: domain 1 of 1, from 370 to 476: score 41.9, E = 2e-09 *->vikeGwLlkkg.gkkswkkRyfvLfddvLlyykdkk.....kkpkgs +i+ G++ + ++ ++R f+Lfd +++++k++ +++ +kg KIAA0424 370 LIYTGEMAWIYqPYGRNQQRVFFLFDHQMVLCKKDLirrdiLYYKGR 416 ipLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerke i++++++v++++d+++++ + kn+F++++++ +e +l++a+ ee+ + KIAA0424 417 IDMDKYEVVDIEDGrdddfnvSMKNAFKLHNkETeEIHLFFAKKLEEKIR 466 Wvkaiqsair<-* W++a+++ + KIAA0424 467 WLRAFREERK 476 //