hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-02572530/chunk_1/iprscan-20080502-02572530.nocrc
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Query sequence: KIAA0436
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
PF00326.11.fs  Prolyl oligopeptidase family              94.5    1.7e-25   1
PF00326.11.ls  Prolyl oligopeptidase family              87.1    4.8e-23   1
PF02897.5.fs   Prolyl oligopeptidase, N-terminal beta    56.1    4.1e-17   1
PF02897.5.ls   Prolyl oligopeptidase, N-terminal beta   -64.9    3.6e-06   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
PF02897.5.ls     1/1      39   393 ..     1   466 []   -64.9  3.6e-06
PF02897.5.fs     1/1     207   295 ..   250   354 ..    56.1  4.1e-17
PF00326.11.fs    1/1     450   612 ..     1   169 [.    94.5  1.7e-25
PF00326.11.ls    1/1     450   675 ..     1   228 []    87.1  4.8e-23

Alignments of top-scoring domains:
PF02897.5.ls: domain 1 of 1, from 39 to 393: score -64.9, E = 3.6e-06
                   *->PptrrdesvvdelhGdvasvkvaDPYrWLeDddRtnpevlawleAEN
                      P+  + e   +e+  +               ++              
    KIAA0436    39    PVKQENEKPLPENMDAF--------------EK-------------- 57   

                   kytedflaqlkplrekifeeltalinyddisaPfrkGgyyYYfrntggkn
                      +  l+ + p++e           y+ i +  ++Gg+ YY        
    KIAA0436    58 --VRTKLETQ-PQEE-----------YEIINVEVKHGGFVYY-------- 85   

                   qsvlcRrdalssyrtegetsdAlnatdfegEeVlLDpNtlsedgdFtval
                   q + c + +      ++e+       d  + eVl +  +l  d  F +  
    KIAA0436    86 QEGCCLVRSK-----DEEA-------DNDNYEVLFNLEELKLDQPFIDCI 123  

                   ggfavSpDgkllAYslsegGsDwytIrfrDvetgredlpDelegvkfsgs
                   +++   pD k++A  + +  s++ t  +++++++  ++ +  + ++ s+ 
    KIAA0436   124 RVA---PDEKYVAAKIRTEDSEASTCVIIKLSDQ--PVMEA-SFPNVSS- 166  

                   ivWapd...nkgfFYsrydepqrgsDddGtetatnlnqkvwrHrLGtpqs
                   ++W +d+++++++FY+  +   r              + v+r   G +  
    KIAA0436   167 FEWVKDeedEDVLFYTFQRN-LR-------------CHDVYRATFGDNKR 202  

                   qDelvfEepddpfswylgaevSrDgkYLfissgsgtdpvnelyvldlgse
                     e  ++e+d+ +  +++++++ D ++L i+++++t+  +e++++d  s 
    KIAA0436   203 N-ERFYTEKDPSY--FVFLYLTKDSRFLTINIMNKTT--SEVWLIDGLS- 246  

                   aiclpkgnghlplrvlvprfdgvyyyvehekgGgdrfyilTNkdgApNfr
                           + +p+ ++++r++gv yyveh+   +d++yilTN  +   f+
    KIAA0436   247 --------PWDPPVLIQKRIHGVLYYVEHR---DDELYILTNVGEPTEFK 285  

                   LvrvdlndpspadwkdvivehredvlleeiavfgnyLvvsyrrdvlsrvq
                   L+r+  ++p+  +w  + +  + ++ +   + f+++ v++  +  l  v 
    KIAA0436   286 LMRTAADTPAIMNWD-LFFTMKRNTKVIDLDMFKDHCVLFLKHSNLLYVN 334  

                   vfdlgapDGlfggaelgkvsfeeflpgvgsvssasgeydsdelfysfsSf
                   v+ l +          + +s++ ++ + g       + d ++ +++ +S 
    KIAA0436   335 VIGLADD---------SVRSLKLPPWACG--FIMDTNSDPKNCPFQLCSP 373  

                   ltPstiYdldldtgerellkdr<-*
                    +P+  Y + ++ g+  l+ ++   
    KIAA0436   374 IRPPKYYTYKFAEGK--LFEET    393  

PF02897.5.fs: domain 1 of 1, from 207 to 295: score 56.1, E = 4.1e-17
                   *->fEepddpfswylgaevSrDgkYLfissgsgtdpvnelyvldlgseai
                      ++e+d+ +  +++++++ D ++L i+++++t+  +e++++d  s   
    KIAA0436   207    YTEKDPSY--FVFLYLTKDSRFLTINIMNKTT--SEVWLIDGLS--- 246  

                   clpkgnghlplrvlvprfdgvyyyvehekgGgdrfyilTNkdgApNfrLv
                         + +p+ ++++r++gv yyveh+   +d++yilTN  +   f+L+
    KIAA0436   247 ------PWDPPVLIQKRIHGVLYYVEHR---DDELYILTNVGEPTEFKLM 287  

                   rvdlndps<-*
                   r+  ++p+   
    KIAA0436   288 RTAADTPA    295  

PF00326.11.fs: domain 1 of 1, from 450 to 612: score 94.5, E = 1.7e-25
                   *->psFsvwnlqlladrGyvvavaniRGsggyGrawhdagkrdlgqnefd
                       +F+  +  +l+d G + a++++RG+g++G +wh +g++ ++ n + 
    KIAA0436   450    MNFR-PERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLA 495  

                   DfiaaaeyLieqgpyvDpdrlaiwGgSyGGyltgaalnkqrpdlFkaava
                   D+ a+++ L  qg +  p+    +  S+GG l+ga  n   p+l +a+  
    KIAA0436   496 DLEACIKTLHGQG-FSQPSLTTLTAFSAGGVLAGALCN-SNPELVRAVTL 543  

                   vvpvvDwltymldtslpyslteaeymewgnpwdeneegYrylspyspydn
                   ++p++D+l++m dt+lp  lt  e +ewgnp   +e++  y++ y py+n
    KIAA0436   544 EAPFLDVLNTMMDTTLP--LTLEELEEWGNPSS-DEKHKNYIKRYCPYQN 590  

                   vkaqaypplLlihGlhDdRVpp<-*
                   +k+q yp++ ++  ++D+RVp+   
    KIAA0436   591 IKPQHYPSIHITAYENDERVPL    612  

PF00326.11.ls: domain 1 of 1, from 450 to 675: score 87.1, E = 4.8e-23
                   *->psFsvwnlqlladrGyvvavaniRGsggyGrawhdagkrdlgqnefd
                       +F+  +  +l+d G + a++++RG+g++G +wh +g++ ++ n + 
    KIAA0436   450    MNFR-PERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLA 495  

                   DfiaaaeyLieqgpyvDpdrlaiwGgSyGGyltgaalnkqrpdlFkaava
                   D+ a+++ L  qg +  p+    +  S+GG l+ga  n   p+l +a+  
    KIAA0436   496 DLEACIKTLHGQG-FSQPSLTTLTAFSAGGVLAGALCN-SNPELVRAVTL 543  

                   vvpvvDwltymldtslpyslteaeymewgnpwdeneegYrylspyspydn
                   ++p++D+l++m dt+lp  lt  e +ewgnp   +e++  y++ y py+n
    KIAA0436   544 EAPFLDVLNTMMDTTLP--LTLEELEEWGNPSS-DEKHKNYIKRYCPYQN 590  

                   vkaqaypplLlihGlhDdRVppaealklvaaLq...........alktGk
                   +k+q yp++ ++  ++D+RVp+     +  +L++   ++ +++++ ++  
    KIAA0436   591 IKPQHYPSIHITAYENDERVPLKGIVSYTEKLKeaiaehakdtgEGYQTP 640  

                   npvlllifpdeGHLSgggkprnkrlkeyarelaFllkvlggt<-*
                   n + l i p+ +H   +  +++k    +  +  Fl + lg +   
    KIAA0436   641 N-IILDIQPGGNH---VIEDSHKK---ITAQIKFLYEELGLD    675  

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