hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-05453389/chunk_1/iprscan-20080502-05453389.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0534 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF01437.15.fs Plexin repeat 187.3 1.1e-60 5 PF01437.15.ls Plexin repeat 195.8 9.2e-56 5 PF01344.15.fs Kelch motif 89.2 1.7e-24 4 PF01344.15.ls Kelch motif 85.0 2.2e-22 4 PF07646.5.ls Kelch motif 69.2 1.2e-17 5 PF07646.5.fs Kelch motif 67.8 1.4e-17 4 PF00053.14.fs Laminin EGF-like (Domains III and V) 38.4 1.8e-10 2 PF00059.11.ls Lectin C-type domain 44.0 4.7e-10 1 PF00059.11.fs Lectin C-type domain 42.2 4.9e-10 1 PF00053.14.ls Laminin EGF-like (Domains III and V) 41.9 2e-09 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF01344.15.fs 1/4 3 51 .. 1 45 [] 22.5 1.4e-05 PF07646.5.fs 1/4 3 51 .. 1 54 [] 26.5 2.4e-06 PF01344.15.ls 1/4 3 51 .. 1 45 [] 24.5 0.00034 PF07646.5.ls 1/5 3 51 .. 1 54 [] 28.4 2.3e-05 PF01344.15.ls 2/4 115 167 .. 1 45 [] 8.1 0.44 PF07646.5.fs 3/4 169 223 .. 1 54 [] 16.0 0.0018 PF01344.15.ls 3/4 169 223 .. 1 45 [] 30.6 5e-06 PF07646.5.ls 3/5 169 223 .. 1 54 [] 18.0 0.032 PF01344.15.fs 3/4 169 223 .. 1 45 [] 28.6 2.6e-07 PF01344.15.fs 4/4 229 261 .. 1 33 [. 25.7 1.8e-06 PF07646.5.fs 4/4 229 261 .. 1 42 [. 19.6 0.00018 PF01344.15.ls 4/4 229 273 .. 1 45 [] 21.8 0.0023 PF07646.5.ls 4/5 229 273 .. 1 54 [] 14.2 0.45 PF01437.15.fs 2/5 315 358 .. 1 63 [] 30.2 2.7e-09 PF01437.15.ls 2/5 315 358 .. 1 63 [] 31.9 2.1e-06 PF01437.15.ls 3/5 364 409 .. 1 63 [] 32.9 1e-06 PF01437.15.fs 3/5 364 409 .. 1 63 [] 31.2 1.3e-09 PF00059.11.fs 1/1 414 523 .. 1 125 [] 42.2 4.9e-10 PF00059.11.ls 1/1 414 523 .. 1 125 [] 44.0 4.7e-10 PF01437.15.ls 4/5 538 588 .. 1 63 [] 60.5 5.1e-15 PF01437.15.fs 4/5 538 588 .. 1 63 [] 58.8 1.2e-18 PF01437.15.ls 5/5 591 661 .. 1 63 [] 57.7 3.5e-14 PF01437.15.fs 5/5 591 661 .. 1 63 [] 55.9 1e-17 PF00053.14.fs 1/2 663 706 .. 1 59 [] 27.7 2.2e-07 PF00053.14.ls 1/2 663 706 .. 1 59 [] 29.5 1.1e-05 PF00053.14.ls 2/2 709 755 .. 1 59 [] 12.4 0.0012 Alignments of top-scoring domains: PF01344.15.fs: domain 1 of 4, from 3 to 51: score 22.5, E = 1.4e-05 *->pRsgagvvvldgkiYviGGydg....qslnsvevYDpetntWtklps R+g++ + ++ i+ GG+ +++++ ++ +v++ +++W+ ++ KIAA0534 3 QRYGHSLALYQENIFMYGGRIEtndgNVTDELWVFNIHSQSWSTKTP 49 mp<-* KIAA0534 50 TV 51 PF07646.5.fs: domain 1 of 4, from 3 to 51: score 26.5, E = 2.4e-06 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +ry+h+++++++ ++++GG+ + n++ +++ l+v++ +++W KIAA0534 3 QRYGHSLALYQENIFMYGGR-----IETNDGNVTDELWVFNIHSQSW 44 eklpalp<-* + ++ KIAA0534 45 STKTPTV 51 PF01344.15.ls: domain 1 of 4, from 3 to 51: score 24.5, E = 0.00034 *->pRsgagvvvldgkiYviGGydg....qslnsvevYDpetntWtklps R+g++ + ++ i+ GG+ +++++ ++ +v++ +++W+ ++ KIAA0534 3 QRYGHSLALYQENIFMYGGRIEtndgNVTDELWVFNIHSQSWSTKTP 49 mp<-* KIAA0534 50 TV 51 PF07646.5.ls: domain 1 of 5, from 3 to 51: score 28.4, E = 2.3e-05 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +ry+h+++++++ ++++GG+ + n++ +++ l+v++ +++W KIAA0534 3 QRYGHSLALYQENIFMYGGR-----IETNDGNVTDELWVFNIHSQSW 44 eklpalp<-* + ++ KIAA0534 45 STKTPTV 51 PF01344.15.ls: domain 2 of 4, from 115 to 167: score 8.1, E = 0.44 *->pRsgagvvv..ldgkiYviGGydg......qslnsvevYDpetntWt +g+++v++++ iYv GGy ++++ +++ ++Y + t+tWt KIAA0534 115 GGYGHTSVYdeITKSIYVHGGYKAlpgnkyGLVDDLYKYEVNTKTWT 161 klpsmp<-* +l + + KIAA0534 162 ILKESG 167 PF07646.5.fs: domain 3 of 4, from 169 to 223: score 16.0, E = 0.0018 *->pryphasvvpggklyvvGGs.fkgnrgtgngdesssdllvldpetnv ry h++v+++g ++++GG + ++ + + ++s d+l +d + KIAA0534 169 ARYLHSAVLINGAMLIFGGNtHNDTSLSNGAKCFSADFLAYDIACDE 215 Weklpalp<-* W+ lp++ KIAA0534 216 WKILPKPN 223 PF01344.15.ls: domain 3 of 4, from 169 to 223: score 30.6, E = 5e-06 *->pRsgagvvvldgkiYviGGydg..........qslnsvevYDpetnt +R+ +++v ++g + ++GG + ++++ +++ + ++ ++ +YD ++ KIAA0534 169 ARYLHSAVLINGAMLIFGGNTHndtslsngakCFSADFLAYDIACDE 215 Wtklpsmp<-* W++lp ++ KIAA0534 216 WKILPKPN 223 PF07646.5.ls: domain 3 of 5, from 169 to 223: score 18.0, E = 0.032 *->pryphasvvpggklyvvGGs.fkgnrgtgngdesssdllvldpetnv ry h++v+++g ++++GG + ++ + + ++s d+l +d + KIAA0534 169 ARYLHSAVLINGAMLIFGGNtHNDTSLSNGAKCFSADFLAYDIACDE 215 Weklpalp<-* W+ lp++ KIAA0534 216 WKILPKPN 223 PF01344.15.fs: domain 3 of 4, from 169 to 223: score 28.6, E = 2.6e-07 *->pRsgagvvvldgkiYviGGydg..........qslnsvevYDpetnt +R+ +++v ++g + ++GG + ++++ +++ + ++ ++ +YD ++ KIAA0534 169 ARYLHSAVLINGAMLIFGGNTHndtslsngakCFSADFLAYDIACDE 215 Wtklpsmp<-* W++lp ++ KIAA0534 216 WKILPKPN 223 PF01344.15.fs: domain 4 of 4, from 229 to 261: score 25.7, E = 1.8e-06 *->pRsgagvvvldgkiYviGGydgqslnsvevYDp<-* R g+++vv++g +Y++GG++++ ln++ vY p KIAA0534 229 NRFGHSAVVINGSMYIFGGFSSVLLNDILVYKP 261 PF07646.5.fs: domain 4 of 4, from 229 to 261: score 19.6, E = 0.00018 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldp<-* +r +h++vv++g +y++GG+ + +++d+lv++p KIAA0534 229 NRFGHSAVVINGSMYIFGGF---------SSVLLNDILVYKP 261 PF01344.15.ls: domain 4 of 4, from 229 to 273: score 21.8, E = 0.0023 *->pRsgagvvvldgkiYviGGydgqslnsvevYDpetntWtklpsmp<- R g+++vv++g +Y++GG++++ ln++ vY p + + + ++ KIAA0534 229 NRFGHSAVVINGSMYIFGGFSSVLLNDILVYKPPNCKAFRDEELC 273 * KIAA0534 - - PF07646.5.ls: domain 4 of 5, from 229 to 273: score 14.2, E = 0.45 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +r +h++vv++g +y++GG+ + +++d+lv++p + KIAA0534 229 NRFGHSAVVINGSMYIFGGF---------SSVLLNDILVYKPPNCKA 266 eklpalp<-* + l+ KIAA0534 267 FRDEELC 273 PF01437.15.fs: domain 2 of 5, from 315 to 358: score 30.2, E = 2.7e-09 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep +C +y +C+sC+a+ +C+WC + ++C++ ++ +C+ s+ KIAA0534 315 RCYRYADCASCTANTN--GCQWCDD-KKCISANS------NCSMSV- 351 endqwldwswssskCp<-* + kC+ KIAA0534 352 ---------KNYTKCH 358 PF01437.15.ls: domain 2 of 5, from 315 to 358: score 31.9, E = 2.1e-06 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep +C +y +C+sC+a+ +C+WC + ++C++ ++ +C+ s+ KIAA0534 315 RCYRYADCASCTANTN--GCQWCDD-KKCISANS------NCSMSV- 351 endqwldwswssskCp<-* + kC+ KIAA0534 352 ---------KNYTKCH 358 PF01437.15.ls: domain 3 of 5, from 364 to 409: score 32.9, E = 1e-06 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep C +tsC sC ++ +C+W+++++ C ++a+ +C +++ KIAA0534 364 ICNKLTSCKSCSLNL---NCQWDQRQQECQALPAH-----LCGEGW- 401 endqwldwswssskCp<-* s+ ++ C KIAA0534 402 --------SHIGDACL 409 PF01437.15.fs: domain 3 of 5, from 364 to 409: score 31.2, E = 1.3e-09 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprsep C +tsC sC ++ +C+W+++++ C ++a+ +C +++ KIAA0534 364 ICNKLTSCKSCSLNL---NCQWDQRQQECQALPAH-----LCGEGW- 401 endqwldwswssskCp<-* s+ ++ C KIAA0534 402 --------SHIGDACL 409 PF00059.11.fs: domain 1 of 1, from 414 to 523: score 42.2, E = 4.9e-10 *->esktWaeAelaCqkegghAHLvsIqsaeEqsfvvafltsltkksnty ++ +++ A+l+C ++ g+ L+s + E fv + +++ t + + KIAA0534 414 SRENYDNAKLYCYNLSGN--LASLTTSKEVEFVLDEIQKYTQ-QKVS 457 aWIGLtdintegtwvwegwetdgspvnyt.enWapgePnnrgnhGgnEdC W+GL++in + +w w d+sp ++t+ W pgePn+ ++C KIAA0534 458 PWVGLRKINIS-YWGW----EDMSPFTNTtLQWLPGEPND------SGFC 496 veiytdtdflaGkWnDepCdskl.pyvCef<-* + + + + ++ +pC s+ ++ vCe+ KIAA0534 497 AYLERAAV---AGLKANPCTSMAnGLVCEK 523 PF00059.11.ls: domain 1 of 1, from 414 to 523: score 44.0, E = 4.7e-10 *->esktWaeAelaCqkegghAHLvsIqsaeEqsfvvafltsltkksnty ++ +++ A+l+C ++ g+ L+s + E fv + +++ t + + KIAA0534 414 SRENYDNAKLYCYNLSGN--LASLTTSKEVEFVLDEIQKYTQ-QKVS 457 aWIGLtdintegtwvwegwetdgspvnyt.enWapgePnnrgnhGgnEdC W+GL++in + +w w d+sp ++t+ W pgePn+ ++C KIAA0534 458 PWVGLRKINIS-YWGW----EDMSPFTNTtLQWLPGEPND------SGFC 496 veiytdtdflaGkWnDepCdskl.pyvCef<-* + + + + ++ +pC s+ ++ vCe+ KIAA0534 497 AYLERAAV---AGLKANPCTSMAnGLVCEK 523 PF01437.15.ls: domain 4 of 5, from 538 to 588: score 60.5, E = 5.1e-15 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs +Cs +tsCs C+++ +C+WCss++rC+ +ay+ sf+yg+C ++ KIAA0534 538 PCSLRTSCSNCTSNGM--ECMWCSSTKRCVDSNAYIiSFpYGQCLEW 582 ependqwldwswssskCp<-* + +++C KIAA0534 583 Q------------TATCS 588 PF01437.15.fs: domain 4 of 5, from 538 to 588: score 58.8, E = 1.2e-18 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs +Cs +tsCs C+++ +C+WCss++rC+ +ay+ sf+yg+C ++ KIAA0534 538 PCSLRTSCSNCTSNGM--ECMWCSSTKRCVDSNAYIiSFpYGQCLEW 582 ependqwldwswssskCp<-* + +++C KIAA0534 583 Q------------TATCS 588 PF01437.15.ls: domain 5 of 5, from 591 to 661: score 57.7, E = 3.5e-14 *->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayt.s.... nCs++++C++CL+ + +CgWC++++++++g+C+ gs++++++ + KIAA0534 591 NCSGLRTCGQCLEQP---GCGWCNDpsntgRGHCIEGSSRGpMklig 634 .......f.ygeCprse.pendqwldwswssskCp<-* ++++ +++++Cp +++e ws+ +Cp KIAA0534 635 mhhnemvLdTNLCPKEKnYE--------WSFIQCP 661 PF01437.15.fs: domain 5 of 5, from 591 to 661: score 55.9, E = 1e-17 *->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayt.s.... nCs++++C++CL+ + +CgWC++++++++g+C+ gs++++++ + KIAA0534 591 NCSGLRTCGQCLEQP---GCGWCNDpsntgRGHCIEGSSRGpMklig 634 .......f.ygeCprse.pendqwldwswssskCp<-* ++++ +++++Cp +++e ws+ +Cp KIAA0534 635 mhhnemvLdTNLCPKEKnYE--------WSFIQCP 661 PF00053.14.fs: domain 1 of 2, from 663 to 706: score 27.7, E = 2.2e-07 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+Cn+h+ tC +C Ck +tG++C C+pGy KIAA0534 663 CQCNGHS-----TCIN--------NNVCEQCKNLTTGKQCQDCMPGY 696 yglpsgdpgqgC<-* yg+p+ + g +C KIAA0534 697 YGDPT-NGG-QC 706 PF00053.14.ls: domain 1 of 2, from 663 to 706: score 29.5, E = 1.1e-05 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+Cn+h+ tC +C Ck +tG++C C+pGy KIAA0534 663 CQCNGHS-----TCIN--------NNVCEQCKNLTTGKQCQDCMPGY 696 yglpsgdpgqgC<-* yg+p+ + g +C KIAA0534 697 YGDPT-NGG-QC 706 PF00053.14.ls: domain 2 of 2, from 709 to 755: score 12.4, E = 0.0012 *->CdCnphGslsddtCdsddelfgeetGqClkCkp.nvtGrrCdrC..k C+C++h+ C++ +tG C C ++ G++C C+++ KIAA0534 709 CTCSGHA----NICHL-------HTGKCF-CTTkGIKGDQCQLCdsE 743 pGyyglpsgdpgqgC<-* y g+ ++ C KIAA0534 744 NRYVGN---PLRGTC 755 //