hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-05503722/chunk_1/iprscan-20080502-05503722.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0537 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00069.15.ls Protein kinase domain 366.3 4.4e-107 1 PF00069.15.fs Protein kinase domain 364.4 1.6e-106 1 PF07714.7.fs Protein tyrosine kinase 126.4 1.4e-36 2 PF07714.7.ls Protein tyrosine kinase 117.6 3.4e-32 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00069.15.fs 1/1 92 343 .. 1 287 [] 364.4 1.6e-106 PF07714.7.fs 1/2 92 243 .. 1 166 [. 122.0 2.6e-35 PF07714.7.ls 1/1 92 341 .. 1 272 [] 117.6 3.4e-32 PF00069.15.ls 1/1 92 343 .. 1 287 [] 366.3 4.4e-107 Alignments of top-scoring domains: PF00069.15.fs: domain 1 of 1, from 92 to 343: score 364.4, E = 1.6e-106 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr yel e+lG+G++G+V++a+++ +g++VA+K i+k+k+k+++d+ ++r KIAA0537 92 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIR 138 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse + Ei+i+ +L+Hp+I+ +++vfe+kd++ +++Ey+ +G +L+dy+s KIAA0537 139 R-EIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKG----ELYDYIS- 182 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv ++++l se+e +++++Qi++++ Y+H+ng++HRDLK+eNILld+n++ KIAA0537 183 --ERRRL--SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCN 228 vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD + KiaDFGl+ + ++++ l+tf+G+p Y++PE+++g+++ g++vD KIAA0537 229 I----KIADFGLSNL--YqKDKfLQTFCGSPLYASPEIVNGRPYRGPEVD 272 vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi W+lGv+ly l+ G PF+g d++ lir+i +++++++ + KIAA0537 273 SWALGVLLYTLVYGTMPFDGF-----DHKNLIRQISSGEYREPTQ----- 312 srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* +++a+ Li+++L ++P +R t+e+i +H w+ KIAA0537 313 -----------PSDARGLIRWMLMVNPDRRATIEDIANHWWV 343 PF07714.7.fs: domain 1 of 2, from 92 to 243: score 122.0, E = 2.6e-35 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.ke.igaseee +l+++LG+G +G+V ++t + + VA+K+++k++i+ ++ KIAA0537 92 YELQETLGKGTYGKVKRATER----FSGRVVAIKSIrKDkIKDEQD- 133 ieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegG + rE++iM++l +Hp+i++ + v ++ + i++Ey+ +G KIAA0537 134 --MVHIRREIEIMSSL-NHPHIISIYEVFEN-KDK----IVIIMEYASKG 175 dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL L+d+ + +r+L+ + +f +Qi ++ Y + ++ vHRDL N+L KIAA0537 176 ELYDYISE---RRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENIL 222 VsenlvVKIsDFGLaRdiynd<-* +++n +KI+DFGL+ + ++d KIAA0537 223 LDDNCNIKIADFGLSNLYQKD 243 PF07714.7.ls: domain 1 of 1, from 92 to 341: score 117.6, E = 3.4e-32 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.ke.igaseee +l+++LG+G +G+V ++t + + VA+K+++k++i+ ++ KIAA0537 92 YELQETLGKGTYGKVKRATER----FSGRVVAIKSIrKDkIKDEQD- 133 ieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegG + rE++iM++l +Hp+i++ + v ++ + i++Ey+ +G KIAA0537 134 --MVHIRREIEIMSSL-NHPHIISIYEVFEN-KDK----IVIIMEYASKG 175 dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL L+d+ + +r+L+ + +f +Qi ++ Y + ++ vHRDL N+L KIAA0537 176 ELYDYISE---RRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENIL 222 VsenlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslkygk..F +++n +KI+DFGL+ + ++d ++ g++l +PE + +g++ KIAA0537 223 LDDNCNIKIADFGLSNLYQKDKFL-QTFCGSPL---YASPE-IVNGRpyR 267 tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenC + D W+ GVlL+ ++ G +P + g + ++ ++ +G+ ++ + KIAA0537 268 GPEVDSWALGVLLYTLVY-GTMP-FDGFDHKNLIRQI-SSGEYREPTQ-- 312 PdelYdlMlqCWaedPedRPtFselveeL<-* P + l++ + +P++R t +++ ++ KIAA0537 313 PSDARGLIRWMLMVNPDRRATIEDIANHW 341 PF00069.15.ls: domain 1 of 1, from 92 to 343: score 366.3, E = 4.4e-107 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr yel e+lG+G++G+V++a+++ +g++VA+K i+k+k+k+++d+ ++r KIAA0537 92 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIR 138 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse + Ei+i+ +L+Hp+I+ +++vfe+kd++ +++Ey+ +G +L+dy+s KIAA0537 139 R-EIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKG----ELYDYIS- 182 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv ++++l se+e +++++Qi++++ Y+H+ng++HRDLK+eNILld+n++ KIAA0537 183 --ERRRL--SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCN 228 vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD + KiaDFGl+ + ++++ l+tf+G+p Y++PE+++g+++ g++vD KIAA0537 229 I----KIADFGLSNL--YqKDKfLQTFCGSPLYASPEIVNGRPYRGPEVD 272 vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi W+lGv+ly l+ G PF+g d++ lir+i +++++++ + KIAA0537 273 SWALGVLLYTLVYGTMPFDGF-----DHKNLIRQISSGEYREPTQ----- 312 srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* +++a+ Li+++L ++P +R t+e+i +H w+ KIAA0537 313 -----------PSDARGLIRWMLMVNPDRRATIEDIANHWWV 343 //