hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-07223052/chunk_1/iprscan-20080502-07223052.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0588 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00028.8.fs Cadherin domain 309.1 7.4e-90 6 PF00028.8.ls Cadherin domain 304.0 2.5e-88 5 PF08266.2.fs Cadherin-like 165.3 5.9e-48 1 PF08266.2.ls Cadherin-like 167.3 3.7e-47 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF08266.2.ls 1/1 35 118 .. 1 84 [] 167.3 3.7e-47 PF08266.2.fs 1/1 35 118 .. 1 84 [] 165.3 5.9e-48 PF00028.8.fs 2/6 144 239 .. 1 107 [] 32.8 8.7e-09 PF00028.8.ls 1/5 144 239 .. 1 107 [] 34.7 3.1e-07 PF00028.8.fs 3/6 253 344 .. 1 107 [] 79.8 2.8e-22 PF00028.8.ls 2/5 253 344 .. 1 107 [] 81.7 2.2e-21 PF00028.8.fs 4/6 358 449 .. 1 107 [] 62.6 2.5e-17 PF00028.8.ls 3/5 358 449 .. 1 107 [] 64.4 3.3e-16 PF00028.8.ls 4/5 463 559 .. 1 107 [] 73.1 8e-19 PF00028.8.fs 5/6 463 559 .. 1 107 [] 71.3 7.9e-20 PF00028.8.ls 5/5 581 671 .. 1 107 [] 50.1 6.7e-12 PF00028.8.fs 6/6 588 671 .. 9 107 .] 54.5 5.3e-15 Alignments of top-scoring domains: PF08266.2.ls: domain 1 of 1, from 35 to 118: score 167.3, E = 3.7e-47 *->gqirYSVpEEterGsfVGNlAKDLGLdvqeLaaRgaRivSggnkqyF qirYSVpEE+e+Gs VG++ +DLGL+++eLa+Rg+Ri+ +g++q+F KIAA0588 35 TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 81 qlnletGdLlvnERiDREeLCgqsepCvLhlevllEn<-* +ln+++G+L++++RiDREeLC +C L+l++l+E+ KIAA0588 82 ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMED 118 PF08266.2.fs: domain 1 of 1, from 35 to 118: score 165.3, E = 5.9e-48 *->gqirYSVpEEterGsfVGNlAKDLGLdvqeLaaRgaRivSggnkqyF qirYSVpEE+e+Gs VG++ +DLGL+++eLa+Rg+Ri+ +g++q+F KIAA0588 35 TQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLF 81 qlnletGdLlvnERiDREeLCgqsepCvLhlevllEn<-* +ln+++G+L++++RiDREeLC +C L+l++l+E+ KIAA0588 82 ALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMED 118 PF00028.8.fs: domain 2 of 6, from 144 to 239: score 32.8, E = 8.7e-09 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr ++ ++Ena++ + +A D+D g N+ +Y ++++ +F+ KIAA0588 144 LEIKISENAATEMRFPLPHAWDPD--IGKNSLQSYELSPNT---HFS 185 IdpdtGdnegi...isttkpLDREeifngeYeLtveAtDadpllasgggp + ++G + + +++ +++ LDREe ++L++ A+D+ g p KIAA0588 186 LIVQNGADGSKypeLVLKRALDREEK--AAHHLVLTASDG-------GDP 226 plsstatvtitVl<-* +++ta++++ Vl KIAA0588 227 VRTGTARIRVMVL 239 PF00028.8.ls: domain 1 of 5, from 144 to 239: score 34.7, E = 3.1e-07 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr ++ ++Ena++ + +A D+D g N+ +Y ++++ +F+ KIAA0588 144 LEIKISENAATEMRFPLPHAWDPD--IGKNSLQSYELSPNT---HFS 185 IdpdtGdnegi...isttkpLDREeifngeYeLtveAtDadpllasgggp + ++G + + +++ +++ LDREe ++L++ A+D+ g p KIAA0588 186 LIVQNGADGSKypeLVLKRALDREEK--AAHHLVLTASDG-------GDP 226 plsstatvtitVl<-* +++ta++++ Vl KIAA0588 227 VRTGTARIRVMVL 239 PF00028.8.fs: domain 3 of 6, from 253 to 344: score 79.8, E = 2.8e-22 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp..ggw y asvpEn + Gt +l+v+AtD+D +g N+ +rYs+ + + ++ KIAA0588 253 YRASVPENLALGTQLLVVNATDPD--EGVNAEVRYSFRYVDDkaAQV 297 FrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggpp F++d ++G+ ist +LD Ee g Y v A+D++ + KIAA0588 298 FKLDCNSGT----ISTIGELDHEES--GFYQMEVQAMDNA---------G 332 lsstatvtitVl<-* s++a v itVl KIAA0588 333 YSARAKVLITVL 344 PF00028.8.ls: domain 2 of 5, from 253 to 344: score 81.7, E = 2.2e-21 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp..ggw y asvpEn + Gt +l+v+AtD+D +g N+ +rYs+ + + ++ KIAA0588 253 YRASVPENLALGTQLLVVNATDPD--EGVNAEVRYSFRYVDDkaAQV 297 FrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggpp F++d ++G+ ist +LD Ee g Y v A+D++ + KIAA0588 298 FKLDCNSGT----ISTIGELDHEES--GFYQMEVQAMDNA---------G 332 lsstatvtitVl<-* s++a v itVl KIAA0588 333 YSARAKVLITVL 344 PF00028.8.fs: domain 4 of 6, from 358 to 449: score 62.6, E = 2.5e-17 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr svpEn+p+Gt ++ +++ D D + Ng++ +i g+ p F+ KIAA0588 358 LASSVPENSPRGTLIALLNVNDQD--SEENGQVICFIQGNLP---FK 399 IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls +++ G + + t LDRE+ + Y++tv AtD+ g+ppls KIAA0588 400 LEKSYGNYYS-LVTDIVLDREQV--PSYNITVTATDR-------GTPPLS 439 statvtitVl<-* +++ + +V KIAA0588 440 TETHISLNVA 449 PF00028.8.ls: domain 3 of 5, from 358 to 449: score 64.4, E = 3.3e-16 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr svpEn+p+Gt ++ +++ D D + Ng++ +i g+ p F+ KIAA0588 358 LASSVPENSPRGTLIALLNVNDQD--SEENGQVICFIQGNLP---FK 399 IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls +++ G + + t LDRE+ + Y++tv AtD+ g+ppls KIAA0588 400 LEKSYGNYYS-LVTDIVLDREQV--PSYNITVTATDR-------GTPPLS 439 statvtitVl<-* +++ + +V KIAA0588 440 TETHISLNVA 449 PF00028.8.ls: domain 4 of 5, from 463 to 559: score 73.1, E = 8e-19 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp..... ysa +pEn p+G ++ +vtA+D+D + N++i+Ys+ ++ ++ + KIAA0588 463 YSAYIPENNPRGVSLVSVTAHDPD--CEENAQITYSLAENTIqgasl 507 ggwFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgg + +I++dtG+ ++ + D+E+ + + v+A+D+ g KIAA0588 508 SSYVSINSDTGV----LYALSSFDYEQF--RDLQVKVMARDN-------G 544 gpplsstatvtitVl<-* pplss +++ Vl KIAA0588 545 HPPLSSNVSLSLFVL 559 PF00028.8.fs: domain 5 of 6, from 463 to 559: score 71.3, E = 7.9e-20 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp..... ysa +pEn p+G ++ +vtA+D+D + N++i+Ys+ ++ ++ + KIAA0588 463 YSAYIPENNPRGVSLVSVTAHDPD--CEENAQITYSLAENTIqgasl 507 ggwFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgg + +I++dtG+ ++ + D+E+ + + v+A+D+ g KIAA0588 508 SSYVSINSDTGV----LYALSSFDYEQF--RDLQVKVMARDN-------G 544 gpplsstatvtitVl<-* pplss +++ Vl KIAA0588 545 HPPLSSNVSLSLFVL 559 PF00028.8.ls: domain 5 of 5, from 581 to 671: score 50.1, E = 6.7e-12 *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr + + +p G v+ v A+D+D +g+N+ ++Y++l+ +++g F+ KIAA0588 581 VELAPRSAEP-GYLVTKVVAVDRD--SGQNAWLSYRLLKASEPGLFS 624 IdpdtGdnegiisttkp.LDREeifngeYeLtveAtDadpllasgggppl + +tG+ ++t++ LDR + + +L+v ++D+ g+ppl KIAA0588 625 VGLHTGE----VRTARAlLDRDAL--KQ-SLVVAVQDH-------GQPPL 660 sstatvtitVl<-* s+t+t+t+ V KIAA0588 661 SATVTLTVAVA 671 PF00028.8.fs: domain 6 of 6, from 588 to 671: score 54.5, E = 5.3e-15 *->apvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFrIdpdtGdn a +G v+ v A+D+D +g+N+ ++Y++l+ +++g F++ +tG+ KIAA0588 588 AEPGYLVTKVVAVDRD--SGQNAWLSYRLLKASEPGLFSVGLHTGE- 631 egiisttkp.LDREeifngeYeLtveAtDadpllasgggpplsstatvti ++t++ LDR + + +L+v ++D+ g+ppls+t+t+t+ KIAA0588 632 ---VRTARAlLDRDAL--KQ-SLVVAVQDH-------GQPPLSATVTLTV 668 tVl<-* V KIAA0588 669 AVA 671 //