hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-08165597/chunk_1/iprscan-20080502-08165597.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0620 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF08337.2.ls Plexin cytoplasmic region 1302.9 0 1 PF08337.2.fs Plexin cytoplasmic region 1301.2 0 1 PF01833.14.fs IPT/TIG domain 166.0 2.9e-47 3 PF01833.14.ls IPT/TIG domain 166.3 7e-47 3 PF01437.15.fs Plexin repeat 97.8 2e-31 3 PF01437.15.ls Plexin repeat 96.1 1e-25 3 PF01403.10.fs Sema domain 25.9 3.7e-07 2 PF01403.10.ls Sema domain -93.9 2.4e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF01403.10.fs 1/2 119 220 .. 1 110 [. 20.6 1.1e-05 PF01403.10.ls 1/1 119 589 .. 1 490 [] -93.9 2.4e-06 PF01437.15.ls 1/3 608 661 .. 1 63 [] 62.1 1.6e-15 PF01437.15.fs 1/3 608 661 .. 1 63 [] 60.3 3.8e-19 PF01437.15.fs 2/3 761 813 .. 1 63 [] 31.5 1e-09 PF01437.15.ls 2/3 761 813 .. 1 63 [] 33.2 8.4e-07 PF01833.14.ls 1/3 951 1038 .. 1 104 [] 70.6 4.8e-18 PF01833.14.fs 1/3 951 1038 .. 1 104 [] 68.8 3.3e-19 PF01833.14.ls 2/3 1041 1125 .. 1 104 [] 71.5 2.5e-18 PF01833.14.fs 2/3 1041 1125 .. 1 104 [] 69.7 1.8e-19 PF01833.14.ls 3/3 1129 1210 .. 1 104 [] 24.3 0.0004 PF01833.14.fs 3/3 1129 1187 .. 1 71 [. 27.6 2.5e-07 PF08337.2.fs 1/1 1404 1948 .. 1 586 [] 1301.2 0 PF08337.2.ls 1/1 1404 1948 .. 1 586 [] 1302.9 0 Alignments of top-scoring domains: PF01403.10.fs: domain 1 of 2, from 119 to 220: score 20.6, E = 1.1e-05 *->frtllldedrgrLyVGArNhvyvLnledlserlqqkigWpss....p + + ld + g++y +A N++y L++++ls+ ++ ++g+ ++++ + KIAA0620 119 TNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDsplcH 165 .geekceeCkmkGkspgcVeteCqNfirVLq.pyndthLyvCGTnaFqPv ++ + +C ++ + + N++++Lq +++++ ++vCG+ + q+ KIAA0620 166 aPQLPQASCEHPRRL-------TDNYNKILQlDPGQGLVVVCGSIY-QGF 207 CtlinlgdrseAviiaetd<-* C+l+++g+ i++++ KIAA0620 208 CQLRRRGN------ISAVA 220 PF01403.10.ls: domain 1 of 1, from 119 to 589: score -93.9, E = 2.4e-06 *->frtllldedrgrLyVGArNhvyvLnledlserlqqkigWpss....p + + ld + g++y +A N++y L++++ls+ ++ ++g+ ++++ + KIAA0620 119 TNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDsplcH 165 .geekceeCkmkGkspgcVeteCqNfirVLq.pyndthLyvCGTnaFqPv ++ + +C ++ + + N++++Lq +++++ ++vCG+ + q+ KIAA0620 166 aPQLPQASCEHPRRL-------TDNYNKILQlDPGQGLVVVCGSIY-QGF 207 CtlinlgdrseAviiaetdcLFsldvekeesGkgrCPydPlhnstsvlvq C+l+++g+ s++ +++ + P+ P + s l+ KIAA0620 208 CQLRRRGN-------------ISAVAVRFPPAAP--PAEPVTVFPSMLN- 241 grtge.....................LYsGtvaDssvaasFsGrdpa.Ir + ++++ ++ + ++ + ++++L +G ++ G+++ ++ KIAA0620 242 -VAANhpnastvglvlppaagaggsrLLVGATYT------GYGSSFFpRN 284 Rslg................................shdplrTeqhdskw Rsl++++ +++++ ++ +++++ + + + ++++ l+ q + KIAA0620 285 RSLEdhrfentpeiairsldtrgdlaklftfdlnpsDDNILKIKQGAKEQ 334 lnePnFVdsypipyvhsf.dDdkVYF.FFrE.taveyspncgkaiysRVa +++ FV++++ p ++ ++ + Y+ + E +a +++ ++ s +a KIAA0620 335 HKLG-FVSAFLHPSDPPPgAQSYAYLaLNSEaRAGDKE----SQARSLLA 379 RvCk.nDvGG..rrylelnkWTTFLKARLnCSvpGeegipkfyFNeLQav R+C ++ GG+ + + e ++ L C +G + + + L +v KIAA0620 380 RICLpHGAGGdaKKLTE-----SYIQLGLQC-AGGAGRGD--LYSRLVSV 421 fllptganlAreLgIserdpviYGVFttssnsiagpgdnSAVCaFsmsdI f +++ ++++VF ++ s a++ A+CaF +d+ KIAA0620 422 FPARE---------------RLFAVFERPQGSPAARAAPAALCAFRFADV 456 rqvFenGpfkhqssEgpnskwlpyrglkvPyPRPGqCpndssgpnytStk r++++ ++ + p + + + v + C + + KIAA0620 457 RAAIRAARTACFVE--PAPDVVAVLD-SVVQGTGPACERKLNI------- 496 dl.PDdtlnfikshpLmdevvpPlhnrPlfvgtsvnyrlTqIaVdkrVra l+P+ + + + + + +Pl P+f ++ T++aV + KIAA0620 497 QLqPEQLDCGAAHLQHPLSILQPLKATPVFRAPGL----TSVAVA---SV 539 gdGqlYtVlFlGTddGtvlKkvvvlsrsss.syeevvleelqvfkdprie + Yt +FlGT +G++l + l ++s vv+ + ++ + e KIAA0620 540 NN---YTAVFLGTVNGRLL--KINL--NESmQ---VVSRRVVTVAYG--E 577 Pvqn.leisskq<-* Pv++ ++ + + KIAA0620 578 PVHHvMQFDPAD 589 PF01437.15.ls: domain 1 of 3, from 608 to 661: score 62.1, E = 1.6e-15 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse. C ++++C++C++a d yCgWC++e rCt+++ +C++s++ KIAA0620 608 ACNVHSTCGDCVGAADA-YCGWCALETRCTLQQ-------DCTNSSq 646 pendqwldwswssskCp<-* ++ w+ +s s+Cp KIAA0620 647 QH--FWTSASEGPSRCP 661 PF01437.15.fs: domain 1 of 3, from 608 to 661: score 60.3, E = 3.8e-19 *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfygeCprse. C ++++C++C++a d yCgWC++e rCt+++ +C++s++ KIAA0620 608 ACNVHSTCGDCVGAADA-YCGWCALETRCTLQQ-------DCTNSSq 646 pendqwldwswssskCp<-* ++ w+ +s s+Cp KIAA0620 647 QH--FWTSASEGPSRCP 661 PF01437.15.fs: domain 2 of 3, from 761 to 813: score 31.5, E = 1e-09 *->nCsq......ytsCssCLaardpfyCgWCssegrCtrgsaytsfyge +Cs++ + ++t C+sCL+a++ C WCs++++C+++++ KIAA0620 761 DCSRtaqvypHTACTSCLSAQW--PCFWCSQQHSCVSNQS------R 799 Cprse.pendqwldwswssskCp<-* C+ s +p +s ++Cp KIAA0620 800 CEASPnP---------TSPQDCP 813 PF01437.15.ls: domain 2 of 3, from 761 to 813: score 33.2, E = 8.4e-07 *->nCsq......ytsCssCLaardpfyCgWCssegrCtrgsaytsfyge +Cs++ + ++t C+sCL+a++ C WCs++++C+++++ KIAA0620 761 DCSRtaqvypHTACTSCLSAQW--PCFWCSQQHSCVSNQS------R 799 Cprse.pendqwldwswssskCp<-* C+ s +p +s ++Cp KIAA0620 800 CEASPnP---------TSPQDCP 813 PF01833.14.ls: domain 1 of 3, from 951 to 1038: score 70.6, E = 4.8e-18 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P I +i+P+sgpl+GGt +Ti+G+nlg + +d + V+ KIAA0620 951 PEIRAIEPLSGPLDGGTLLTIRGRNLG---------RRLSDVAHGVW 988 fggtpvpCdvisssss..tqivCktPpva.ggpsppvvtvsvdgggsgdg +gg++ C++ ++ + +++ivC+t+p++++ + v+v+ + KIAA0620 989 IGGVA--CEPLPDRYTvsEEIVCVTGPAPgPLS----GVVTVNASK---- 1028 rssspvtFtY<-* ++ s +F+Y KIAA0620 1029 EGKSRDRFSY 1038 PF01833.14.fs: domain 1 of 3, from 951 to 1038: score 68.8, E = 3.3e-19 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P I +i+P+sgpl+GGt +Ti+G+nlg + +d + V+ KIAA0620 951 PEIRAIEPLSGPLDGGTLLTIRGRNLG---------RRLSDVAHGVW 988 fggtpvpCdvisssss..tqivCktPpva.ggpsppvvtvsvdgggsgdg +gg++ C++ ++ + +++ivC+t+p++++ + v+v+ + KIAA0620 989 IGGVA--CEPLPDRYTvsEEIVCVTGPAPgPLS----GVVTVNASK---- 1028 rssspvtFtY<-* ++ s +F+Y KIAA0620 1029 EGKSRDRFSY 1038 PF01833.14.ls: domain 2 of 3, from 1041 to 1125: score 71.5, E = 2.5e-18 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P ++s++P+ gp++GGt+iTi+G +l gs ++V+ KIAA0620 1041 PLVHSLEPTMGPKAGGTRITIHGNDLHVGS------------ELQVL 1075 fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs +++t+ pC+ +++ t+i C+ P++a + p+p v v + + g + KIAA0620 1076 VNDTD-PCTELMRTD-TSIACTMPEGAlPAPVP--VCVRFERRG----CV 1117 sspvtFtY<-* + tF Y KIAA0620 1118 HGNLTFWY 1125 PF01833.14.fs: domain 2 of 3, from 1041 to 1125: score 69.7, E = 1.8e-19 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt P ++s++P+ gp++GGt+iTi+G +l gs ++V+ KIAA0620 1041 PLVHSLEPTMGPKAGGTRITIHGNDLHVGS------------ELQVL 1075 fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs +++t+ pC+ +++ t+i C+ P++a + p+p v v + + g + KIAA0620 1076 VNDTD-PCTELMRTD-TSIACTMPEGAlPAPVP--VCVRFERRG----CV 1117 sspvtFtY<-* + tF Y KIAA0620 1118 HGNLTFWY 1125 PF01833.14.ls: domain 3 of 3, from 1129 to 1210: score 24.3, E = 0.0004 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt PvIt+isP+++p+sGG +iT+ G+ + +++ + V KIAA0620 1129 PVITAISPRRSPVSGGRTITVAGERFHMVQN----------VSMAVH 1165 fggtpv.pCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgr g++ + C+v +s+ i+C +P + + +p v++ ++g KIAA0620 1166 HIGREPtLCKVLNSTL---ITCPSPGALsNASAP--VDFFINGRA----- 1205 ssspvtFtY<-* ++ KIAA0620 1206 ----YADEV 1210 PF01833.14.fs: domain 3 of 3, from 1129 to 1187: score 27.6, E = 2.5e-07 *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt PvIt+isP+++p+sGG +iT+ G+ + +++ + V KIAA0620 1129 PVITAISPRRSPVSGGRTITVAGERFHMVQN----------VSMAVH 1165 fggtpv.pCdvissssstqivCktP<-* g++ + C+v +s+ i+C +P KIAA0620 1166 HIGREPtLCKVLNSTL---ITCPSP 1187 PF08337.2.fs: domain 1 of 1, from 1404 to 1948: score 1301.2, E = 0 *->sGiPfLDYktYaeRvFFpk......................pGhedH +GiPfL+Yk++++R+FFpk ++ +++ ++++ ++++++ +e+H KIAA0620 1404 QGIPFLEYKHFVTRTFFPKcsslyeeryvlpsqtlnsqgssQAQETH 1450 PvLkdlevpesraptveegLtqFsqLLnNKsFLltfIhTLEsQrsFSvRD P+L+++++pes++p++eeg+++Fs+LLnNK+FL++f+h+LE+Q++F+vRD KIAA0620 1451 PLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRD 1500 RvnvASLLmvaLqgKLeYcTdILktLLrdLIeksvesKnnPKLmLRRTES R+ +ASLL++aL+gKLeY+T+I+k+LL+dLI++s ++K nPKLmLRRTES KIAA0620 1501 RCSLASLLTIALHGKLEYYTSIMKELLVDLIDAS-AAK-NPKLMLRRTES 1548 VVEKMLTNWmSiCLYdfLKetaGepLflLfkAIKqQieKGPVDAvTgkAR VVEKMLTNWmSiC+Y++L+et+Gep+flL++AIKqQi+KG++DA+TgkAR KIAA0620 1549 VVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKAR 1598 YTLnEekLLReqveykpltlnCVilevqpegdeadgvrnvpVkVLDCDTI YTLnEe+LLRe++e+kp++ln V+ +q++g+++ +V+ +D+DT+ KIAA0620 1599 YTLNEEWLLRENIEAKPRNLN-VS--FQGCGMDS-----LSVRAMDTDTL 1640 tQVKeKiLdavYkgtPySqRPrvedldLEWrtGrrghliLqDveDvTski tQVKeKiL+a++k++PySq+Pr+ed+dLEW+ +++++iL+D +D+Ts++ KIAA0620 1641 TQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRD-LDDTSVV 1689 egglwKRLNTLaHYgVpDGAtlaLvpkqntassynisilStksekstsil e+g +K+LNTLaHY++p+GA+la+++ KIAA0620 1690 EDG-RKKLNTLAHYKIPEGASLAMSL------------------------ 1714 tdnssryestlrldssddslgsrsdlledgqesGvklwHLVkPtdelveq +d++d++lg+++dl+++ k++HLV+Ptdel+e+ KIAA0620 1715 ------------IDKKDNTLGRVKDLDTE------KYFHLVLPTDELAEP 1746 kkgkRqslklkeredrkKaipEIYLTRLLstKGTLQKFVDDLFesILSta kk++Rqs+ rkK++pEIYLTRLLstKGTLQKF+DDLF++ILS+ KIAA0620 1747 KKSHRQSH-------RKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSI- 1788 HrnsalPlAvKYfFDFLDeqAekhgIsDpDvvHiWKsNsLPLRFWVNiiK r++++PlAvKYfFDFL+eqAek+gIsDpD++HiWK+NsLPLRFWVNi+K KIAA0620 1789 -REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILK 1837 NPqFVFDIhKtdsvDAcLSViAQTFMDACStsEhrLGKDSPSNKLLYAKD NPqFVFDI Ktd++DAcLSViAQ+F+DACS+s+++LGKDSP+NKLLYAK+ KIAA0620 1838 NPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKE 1887 IPrYkkmVerYYkdIrdmppiSdQEMnaaLaeeSrkhsnefntlvALnEL IP+Y+k V+rYYk+I+dm+p+S+QEMna+LaeeSrk++nefnt+vA+ E+ KIAA0620 1888 IPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEI 1937 YkYvkKYrdqI<-* YkY+k+Yr qI KIAA0620 1938 YKYAKRYRPQI 1948 PF08337.2.ls: domain 1 of 1, from 1404 to 1948: score 1302.9, E = 0 *->sGiPfLDYktYaeRvFFpk......................pGhedH +GiPfL+Yk++++R+FFpk ++ +++ ++++ ++++++ +e+H KIAA0620 1404 QGIPFLEYKHFVTRTFFPKcsslyeeryvlpsqtlnsqgssQAQETH 1450 PvLkdlevpesraptveegLtqFsqLLnNKsFLltfIhTLEsQrsFSvRD P+L+++++pes++p++eeg+++Fs+LLnNK+FL++f+h+LE+Q++F+vRD KIAA0620 1451 PLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRD 1500 RvnvASLLmvaLqgKLeYcTdILktLLrdLIeksvesKnnPKLmLRRTES R+ +ASLL++aL+gKLeY+T+I+k+LL+dLI++s ++K nPKLmLRRTES KIAA0620 1501 RCSLASLLTIALHGKLEYYTSIMKELLVDLIDAS-AAK-NPKLMLRRTES 1548 VVEKMLTNWmSiCLYdfLKetaGepLflLfkAIKqQieKGPVDAvTgkAR VVEKMLTNWmSiC+Y++L+et+Gep+flL++AIKqQi+KG++DA+TgkAR KIAA0620 1549 VVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKAR 1598 YTLnEekLLReqveykpltlnCVilevqpegdeadgvrnvpVkVLDCDTI YTLnEe+LLRe++e+kp++ln V+ +q++g+++ +V+ +D+DT+ KIAA0620 1599 YTLNEEWLLRENIEAKPRNLN-VS--FQGCGMDS-----LSVRAMDTDTL 1640 tQVKeKiLdavYkgtPySqRPrvedldLEWrtGrrghliLqDveDvTski tQVKeKiL+a++k++PySq+Pr+ed+dLEW+ +++++iL+D +D+Ts++ KIAA0620 1641 TQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRD-LDDTSVV 1689 egglwKRLNTLaHYgVpDGAtlaLvpkqntassynisilStksekstsil e+g +K+LNTLaHY++p+GA+la+++ KIAA0620 1690 EDG-RKKLNTLAHYKIPEGASLAMSL------------------------ 1714 tdnssryestlrldssddslgsrsdlledgqesGvklwHLVkPtdelveq +d++d++lg+++dl+++ k++HLV+Ptdel+e+ KIAA0620 1715 ------------IDKKDNTLGRVKDLDTE------KYFHLVLPTDELAEP 1746 kkgkRqslklkeredrkKaipEIYLTRLLstKGTLQKFVDDLFesILSta kk++Rqs+ rkK++pEIYLTRLLstKGTLQKF+DDLF++ILS+ KIAA0620 1747 KKSHRQSH-------RKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSI- 1788 HrnsalPlAvKYfFDFLDeqAekhgIsDpDvvHiWKsNsLPLRFWVNiiK r++++PlAvKYfFDFL+eqAek+gIsDpD++HiWK+NsLPLRFWVNi+K KIAA0620 1789 -REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILK 1837 NPqFVFDIhKtdsvDAcLSViAQTFMDACStsEhrLGKDSPSNKLLYAKD NPqFVFDI Ktd++DAcLSViAQ+F+DACS+s+++LGKDSP+NKLLYAK+ KIAA0620 1838 NPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKE 1887 IPrYkkmVerYYkdIrdmppiSdQEMnaaLaeeSrkhsnefntlvALnEL IP+Y+k V+rYYk+I+dm+p+S+QEMna+LaeeSrk++nefnt+vA+ E+ KIAA0620 1888 IPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEI 1937 YkYvkKYrdqI<-* YkY+k+Yr qI KIAA0620 1938 YKYAKRYRPQI 1948 //