HUGE

Gene/Protein Characteristic Table for KIAA0653

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK05481
Accession No. :	AB014553
Description :	ICOS ligand precursor.
HUGO Gene Name :	inducible T-cell co-stimulator ligand (ICOSLG)
Clone Name :	hk01718 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4358 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 558 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
EAX09447	4.1e-161	91.3	inducible T-cel...	Homo sapiens
O75144	1.2e-100	100.0	ICOS ligand; B7...	Homo sapiens
AAF34739	3.2e-100	100.0	B7-like protein...	Homo sapiens
XP_531578	1.1e-98	98.3	similar to B7-l...	Pan troglodytes
BAH11654	3.6e-70	100.0	unnamed protein...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR013106 57 173 PF07686 Immunoglobulin V-set

HMMSmart IPR003599 64 177 SM00409 Immunoglobulin subtype

ProfileScan IPR007110 36 171 PS50835 Immunoglobulin-like

IPR007110 183 269 PS50835 Immunoglobulin-like

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR013106	57	173	PF07686	Immunoglobulin V-set
HMMSmart	IPR003599	64	177	SM00409	Immunoglobulin subtype
ProfileScan	IPR007110	36	171	PS50835	Immunoglobulin-like
IPR007110	183	269	PS50835	Immunoglobulin-like

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 297 ATWSILAVLCLLVVVAVAIGWVC 319 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	297	ATWSILAVLCLLVVVAVAIGWVC	319	PRIMARY	23

Expression profile	Description

: RT-PCR Description
: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AGCTTCTGTCCCTCATGCCTG

Primer_r
: GGGTAGGTCTCACAAATGCCG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 21

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: AGCTTCTGTCCCTCATGCCTG
Primer_r	: GGGTAGGTCTCACAAATGCCG
PCR product length	: 172 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Gene/Protein Characteristic Table for KIAA0653

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information