hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-11354644/chunk_1/iprscan-20080502-11354644.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0736 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07690.6.fs Major Facilitator Superfamily 112.4 2.2e-31 2 PF07690.6.ls Major Facilitator Superfamily 108.8 1.4e-29 1 PF00083.14.fs Sugar (and other) transporter 66.0 1.8e-18 1 PF00083.14.ls Sugar (and other) transporter -20.9 3e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00083.14.ls 1/1 174 747 .. 1 488 [] -20.9 3e-06 PF07690.6.fs 1/2 178 326 .. 1 167 [. 65.3 3.4e-18 PF07690.6.ls 1/1 178 715 .. 1 397 [] 108.8 1.4e-29 PF00083.14.fs 1/1 205 385 .. 48 236 .. 66.0 1.8e-18 PF07690.6.fs 2/2 600 715 .. 266 397 .] 47.1 4.4e-13 Alignments of top-scoring domains: PF00083.14.ls: domain 1 of 1, from 174 to 747: score -20.9, E = 3e-06 *->valvaalgGsflfGYDtgvigafltlisflkrfglltssgadeelvg + +v l+ G v+ +f+ +++ + ++ ++++ KIAA0736 174 LYFVLGLAL-MADGVEVFVV-GFVLPSAEKDMCLSDSNK-------- 210 ystvltglivsifsvGcliGslfaGwlgdrfGRkksllianvlfviGall g+ i+ +G ++G+++ G l+dr+GR+ +lli++ + ++ a+ KIAA0736 211 ------GMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFF 254 mgaakgkttiGgksvymlivGRvivGlgvGgisvlvPmYisEiAPkklRG + + +++ ++++R+++G g+Gg + +v Y sE ++RG KIAA0736 255 SSFVQ--------GYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRG 296 alvslyQlaitfGilvAaiiglglnktnnssn...nsdg.....Wriplg s+ +++ +G++ Aa + ++++ ++ ++ ++ + + ++Wr+++ KIAA0736 297 EHLSWLCMFWMIGGVYAAAMAWAIIPHYG--WsfqMGSAyqfhsWRVFVL 344 lqlvpalllligllflPESPRwLvekgkleeArevLakllrgv....... +++ p+++ + +l++ PESPR+++e+gk++eA vL++ +++ + +++ KIAA0736 345 VCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQ-VHDTnmrakgh 393 sdvdqeiqeekdeleasreee.kagkaswlelfsrktrpkyrqrllmgvm ++ + +k+ +++ +e + + +w + ++ + ++ + KIAA0736 394 PERVFSVTHIKTIHQEDELIEiQSDTGTWYQRWGVRA---------LSLG 434 lqifQQltGiNaifYYsptifeslGvsdstasllvtiivgvvNfvfTfia q++ N++ ++p + + + + ++ t+ ++ + + f KIAA0736 435 GQVWG-----NFLSCFGPEYRRITLMMMG---VWFTMSFSYYGLTVWFPD 476 li...flvdrfGRR.................................... +i++ vd++ R + ++++ ++ + + + +++ +++++ +++ + + KIAA0736 477 MIrhlQAVDYASRTkvfpgervehvtfnftlenqihrggqyfndkfiglr 526 .................................................. ++ + +++ ++ ++ +++++ ++ + ++ +++ + + +++ KIAA0736 527 lksvsfedslfeecyfedvtssntffrnctfintvfyntdlfeykfvnsr 576 .................................................. +++ +++++ + + ++++++ + ++ +++ + + KIAA0736 577 linstflhnkegcpldvtgtgegaymvyfvsflgtlavlpgnivsallmd 626 ....pllLlGaagmaicmvvlgasvivallglnkskdpsskaagivaivf + ++ +L G+++m++ +++ +g ++s ++i++ KIAA0736 627 kigrLRMLAGSSVMSCVSCFF------LSFGNSES----------AMIAL 660 illfiafFalgwGpvpwvivsElFPlgvRpkamaiataanwlanfligfl ++lf + ++w+ + v+ El+P+ R+ a+++ a+ la +l + KIAA0736 661 LCLFGGVSIASWNALD-VLTVELYPSDKRTTAFGFLNALCKLAAVLGISI 709 fpiitgaiglflggyvflvfagllvlfiifvfffvPETkGrtLeeieelf f++ +g + ++fa+ +++ + +++PET G +++ KIAA0736 710 FTSFVGITK-----AAPILFASAALALGSSLALKLPETRG-------QVL 747 <-* KIAA0736 - - PF07690.6.fs: domain 1 of 2, from 178 to 326: score 65.3, E = 3.4e-18 *->lflaaflaglgrsllgpalpylassleesslgqtdllspteiglllt l la + g ++++g++lp ++ ls + g+l KIAA0736 178 LGLALMADGVEVFVVGFVLPSAE---KD--MC----LSDSNKGMLGL 215 afalgyalaqplaGrlsDrfGrrvyirlkpvlllglllfalgslllafas + +lg+ ++++l+G l+Dr+Grr ll++l + +++++ + f+ KIAA0736 216 IVYLGMMVGAFLWGGLADRLGRR---Q---CLLISLSVNSVFAFFSSFVQ 259 stslwllliarallqGlgagllapaaaaliadwfppeergralgivsagf + ++l+ r+l +G+g g+ +p + +++++ + e+rg l+++ +++ KIAA0736 260 --GYGTFLFCRLL-SGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFW 306 glGaalggpllggllaalgw<-* +G++ +++++ +++ ++gw KIAA0736 307 MIGGVYAAAMAWAIIPHYGW 326 PF07690.6.ls: domain 1 of 1, from 178 to 715: score 108.8, E = 1.4e-29 *->lflaaflaglgrsllgpalpylassleesslgqtdllspteiglllt l la + g ++++g++lp ++ ls + g+l KIAA0736 178 LGLALMADGVEVFVVGFVLPSAE---KD--MC----LSDSNKGMLGL 215 afalgyalaqplaGrlsDrfGrrvyirlkpvlllglllfalgslllafas + +lg+ ++++l+G l+Dr+Grr ll++l + +++++ + f+ KIAA0736 216 IVYLGMMVGAFLWGGLADRLGRR---Q---CLLISLSVNSVFAFFSSFVQ 259 stslwllliarallqGlgagllapaaaaliadwfppeergralgivsagf + ++l+ r+l +G+g g+ +p + +++++ + e+rg l+++ +++ KIAA0736 260 --GYGTFLFCRLL-SGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFW 306 glGaalggpllggllaalgwwwssgtfWraaFlilg........ilalla +G++ +++++ +++ ++gw F + + ++ +++ l++ KIAA0736 307 MIGGVYAAAMAWAIIPHYGW----------SFQMGSayqfhswrVFVLVC 346 allllvlfllpeppakasgkpeeeeagi...................... a++ +f + + +++ ++ e g ++ ++ +++ + ++ + KIAA0736 347 AFP--SVFAIGALTTQPESPRFFLENGKhdeawmvlkqvhdtnmrakghp 394 .................................................. ++ + + ++ ++++ + ++++++ ++ + + + +++ ++ + KIAA0736 395 ervfsvthiktihqedelieiqsdtgtwyqrwgvralslggqvwgnflsc 444 .................................................. +++ ++ + + + + + + + ++ + + + ++++ + KIAA0736 445 fgpeyrritlmmmgvwftmsfsyygltvwfpdmirhlqavdyasrtkvfp 494 .................................................. +++ + + + + +++ ++++ +++ + + ++ + +++ ++ ++ KIAA0736 495 gervehvtfnftlenqihrggqyfndkfiglrlksvsfedslfeecyfed 544 .................alr.lll.p.lllillalflllaaflalltflp +++++ ++ + ++ + + l++ +++ ++l+ + KIAA0736 545 vtssntffrnctfintvFYNtDLFeYkFVNSRLI--------------NS 580 lylllpllls.saglslsalaagllllalglggllgglllggrlsdrlgr ++l+ + + ++++ + + +++++lg +++l g ++++ l+d++g KIAA0736 581 TFLHNKEGCPlDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIG- 629 glarkgeaeaerrrllllgllllalgllllafapslliallllalvllGl r r+l+ ++++ ++++++l+f++s + +++++l+l+G KIAA0736 630 -----------RLRMLAGSSVMSCVSCFFLSFGNSES--AMIALLCLFGG 666 gfggvfpalnalasdlappeaqerGtasGlyntagslggalgpllgGlll + + al l+++l+p + +r ta+G++n++ l+++lg +++ ++ KIAA0736 667 VSIASWNALDVLTVELYPSD--KRTTAFGFLNALCKLAAVLGISIFTSFV 714 d<-* KIAA0736 715 G 715 PF00083.14.fs: domain 1 of 1, from 205 to 385: score 66.0, E = 1.8e-18 *->ystvltglivsifsvGcliGslfaGwlgdrfGRkksllianvlfviG +s++ g+ i+ +G ++G+++ G l+dr+GR+ +lli++ + ++ KIAA0736 205 LSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVF 251 allmgaakgkttiGgksvymlivGRvivGlgvGgisvlvPmYisEiAPkk a+ + + +++ ++++R+++G g+Gg + +v Y sE + KIAA0736 252 AFFSSFVQ--------GYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQE 293 lRGalvslyQlaitfGilvAaiiglglnktnnssn...nsdg.....Wri +RG s+ +++ +G++ Aa + ++++ ++ ++ ++ + + ++Wr+ KIAA0736 294 KRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYG--WsfqMGSAyqfhsWRV 341 plglqlvpalllligllflPESPRwLvekgkleeArevLakllrgvsdvd ++ +++ p+++ + +l++ PESPR+++e+gk++eA vL++ +d KIAA0736 342 FVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQ------VHD 385 <-* KIAA0736 - - PF07690.6.fs: domain 2 of 2, from 600 to 715: score 47.1, E = 4.4e-13 *->laagllllalglggllgglllggrlsdrlgrglarkgeaeaerrrll + + +++++lg +++l g ++++ l+d++g r r+l KIAA0736 600 AYMVYFVSFLGTLAVLPGNIVSALLMDKIG------------RLRML 634 llgllllalgllllafapslliallllalvllGlgfggvfpalnalasdl + ++++ ++++++l+f++s + +++++l+l+G + + al l+++l KIAA0736 635 AGSSVMSCVSCFFLSFGNSES--AMIALLCLFGGVSIASWNALDVLTVEL 682 appeaqerGtasGlyntagslggalgpllgGllld<-* +p + +r ta+G++n++ l+++lg +++ ++ KIAA0736 683 YPSD--KRTTAFGFLNALCKLAAVLGISIFTSFVG 715 //