hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/smart.HMMs.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-12095879/chunk_1/iprscan-20080502-12095879.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0756 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SM00409 239.1 3.8e-67 6 SM00408 230.1 1.8e-64 6 SM00060 153.0 3.1e-41 4 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SM00409 1/6 95 184 .. 1 58 [] 14.7 4.3 SM00408 1/6 101 172 .. 1 56 [] 19.5 0.051 SM00409 2/6 194 281 .. 1 58 [] 40.2 2.9e-07 SM00408 2/6 200 267 .. 1 56 [] 7.4 0.94 SM00409 3/6 317 398 .. 1 58 [] 57.6 1.6e-12 SM00408 3/6 323 387 .. 1 56 [] 74.0 1.8e-17 SM00409 4/6 407 490 .. 1 58 [] 32.6 5.4e-05 SM00408 4/6 413 479 .. 1 56 [] 44.0 1.9e-08 SM00409 5/6 501 583 .. 1 58 [] 40.0 3.3e-07 SM00408 5/6 507 572 .. 1 56 [] 50.2 2.7e-10 SM00409 6/6 592 674 .. 1 58 [] 54.1 1.8e-11 SM00408 6/6 598 663 .. 1 56 [] 35.0 1e-05 SM00060 1/4 677 760 .. 1 69 [] 51.8 8.7e-11 SM00060 2/4 777 859 .. 1 69 [] 35.6 6.8e-06 SM00060 3/4 875 966 .. 1 69 [] 28.9 0.00072 SM00060 4/4 981 1065 .. 1 69 [] 36.7 3.1e-06 Alignments of top-scoring domains: SM00409: domain 1 of 6, from 95 to 184: score 14.7, E = 4.3 *->pp.vtvkeGesvtLtC.as.....titWy.................. +++ v + +++ ++C+a++++ ++++W+++++ + ++++ + ++ KIAA0756 95 AKdHIVDPRDNILIECeAKgnpapSFHWTrnsrffniakdprvsmrr 141 ....LtInvtpeDse.....sgGtYtCaat..sgsasseqgttLtVl<-* ++++L+I+ + +++++ + G+Y+C a+++ g+a s + ++L+V+ KIAA0756 142 rsgtLVIDFRSG--GrpeeyE-GEYQCFARnkFGTALS-NRIRLQVS 184 SM00408: domain 1 of 6, from 101 to 172: score 19.5, E = 0.051 *->leGqsVtLtCpasgdpvpnItWlk.gkplp...........sgstLt + +++ ++C+a g+p+p+++W++++ + ++++ + ++ ++tL KIAA0756 101 DPRDNILIECEAKGNPAPSFHWTRnSRFFNiakdprvsmrrRSGTLV 147 i...knvs.leDsGlYtCvArNsvg<-* i+ ++ +++e +G+Y+C+ArN+ g KIAA0756 148 IdfrSGGRpEEYEGEYQCFARNKFG 172 SM00409: domain 2 of 6, from 194 to 281: score 40.2, E = 2.9e-07 *->pp.vtvkeGesvtLtC.as......titWy................. +v+v+eG ++tL+C+ +++ +++ i+W++++ + +++++ ++++ KIAA0756 194 LDpVVVQEGAPLTLQCnPPpglpspVIFWMsssmepitqdkrvsqgh 240 ...LtI.nvtpeDsesgGtYtCaat....sgsasseqgttLtVl<-* +++L ++nv ++D + +Y C a+ + ++ +++ +++tL+Vl KIAA0756 241 ngdLYFsNVMLQDMQ--TDYSCNARfhftHTIQQK-NPFTLKVL 281 SM00408: domain 2 of 6, from 200 to 267: score 7.4, E = 0.94 *->leGqsVtLtCp.asgdpvpnItWlk..gkplp........sgstLti +eG ++tL+C + g p p I W ++ +p+ ++++ ++++++ L + KIAA0756 200 QEGAPLTLQCNpPPGLPSPVIFWMSssMEPITqdkrvsqgHNGDLYF 246 knvsleDsGl.YtCvArNsvg<-* +nv l D ++Y+C Ar + KIAA0756 247 SNVMLQDMQTdYSCNARFHFT 267 SM00409: domain 3 of 6, from 317 to 398: score 57.6, E = 1.6e-12 *->pp.vtvkeGesvtLtC.as.....titWy.................. +++ v +G ++ L+C as+ +++ i Wy+++++ ++++ + + ++ KIAA0756 317 ASsQMVLRGMDLLLECiASgvptpDIAWYkkggdlpsdkakfenfnk 363 .LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* L+I+nv++eDs G+Y+C a+++ gs+ ++ ++V+ KIAA0756 364 aLRItNVSEEDS---GEYFCLASnkMGSIRH--TISVRVK 398 SM00408: domain 3 of 6, from 323 to 387: score 74.0, E = 1.8e-17 *->leGqsVtLtCpasgdpvpnItWlk.gkplp........sgstLtikn l G ++ L+C+asg p+p+I W+k+g lp+++ + ++ ++ L+i+n KIAA0756 323 LRGMDLLLECIASGVPTPDIAWYKkGGDLPsdkakfenFNKALRITN 369 vsleDsGlYtCvArNsvg<-* vs+eDsG+Y C+A+N++g KIAA0756 370 VSEEDSGEYFCLASNKMG 387 SM00409: domain 4 of 6, from 407 to 490: score 32.6, E = 5.4e-05 *->pp.vtvkeGesvtLtC.as.....titWy.................. p+++ +Ge+ +L C+a++++++t++W+ ++ + ++ ++++++ KIAA0756 407 PKnLILAPGEDGRLVCrANgnpkpTVQWMvngeplqsappnpnreva 453 ...LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++++++++ + + ++Y+C ++ +g + ++ ++Vl KIAA0756 454 gdtIIFrDTQISSR---AVYQCNTSneHGYLLA--NAFVSVL 490 SM00408: domain 4 of 6, from 413 to 479: score 44.0, E = 1.9e-08 *->leGqsVtLtCpasgdpvpnItWlk.gkplp..........sgstLti +G++ +L C+a+g+p p+++W +g+pl++ +++++++ g t + KIAA0756 413 APGEDGRLVCRANGNPKPTVQWMVnGEPLQsappnpnrevAGDTIIF 459 knvsleDsGlYtCvArNsvg<-* ++ + + + +Y+C +N++g KIAA0756 460 RDTQISSRAVYQCNTSNEHG 479 SM00409: domain 5 of 6, from 501 to 583: score 40.0, E = 3.3e-07 *->pp.vtvkeGesvtLtC.as.....titWy.................. + + v + + +L C++ +++ +t++W++++++++ ++++ + + KIAA0756 501 NQlIRVILYNRTRLDCpFFgspipTLRWFkngqgsnldggnyhvyen 547 ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++L+I+ +++eD+ G+YtC+at+ g+a+ ++L+V+ KIAA0756 548 gsLEIkMIRKEDQ---GIYTCVATniLGKAEN--QVRLEVK 583 SM00408: domain 5 of 6, from 507 to 572: score 50.2, E = 2.7e-10 *->leGqsVtLtCpasgdpvpnItWlk...gkplp.......sgstLtik + + +L Cp g+p p+ +W+k+++g+ l++++ + +++L+ik KIAA0756 507 ILYNRTRLDCPFFGSPIPTLRWFKngqGSNLDggnyhvyENGSLEIK 553 nvsleDsGlYtCvArNsvg<-* +++eD G+YtCvA+N g KIAA0756 554 MIRKEDQGIYTCVATNILG 572 SM00409: domain 6 of 6, from 592 to 674: score 54.1, E = 1.8e-11 *->pp.vtvkeGesvtLtC.as.......titWy................ p+++++++G +v+L+C+++++++ + t++W++++ + +++ ++ + KIAA0756 592 PEdQVARRGTTVQLECrVKhdpslklTVSWLkddeplyignrmkked 638 ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++LtI +v + D+ G YtC+a++ ++ + ++LtVl KIAA0756 639 dsLTIfGVAERDQ---GSYTCVASteLDQDLA--KAYLTVL 674 SM00408: domain 6 of 6, from 598 to 663: score 35.0, E = 1e-05 *->leGqsVtLtCpasgdpvp....nItWlk.gkplp.......sgstLt + G++V+L+C+ +++p+ + +++Wlk+++pl +++ ++ + +Lt KIAA0756 598 RRGTTVQLECR--VKHDPslklTVSWLKdDEPLYignrmkkEDDSLT 642 iknvsleDsGlYtCvArNsvg<-* i v++ D G YtCvA+ + KIAA0756 643 IFGVAERDQGSYTCVASTELD 663 SM00060: domain 1 of 4, from 677 to 760: score 51.8, E = 8.7e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... P+ P++ l++td ++ sv+l+W p + ++++i+ Y+++ KIAA0756 677 PDRPRD---LELTDLAER------SVRLTWIPGdannspITDYVvqf 714 ......................ytltgLkPgaepwteYefrVrAvngnda ++++ +++++ + ++ ++++++++l+ L+P+ +Y+frV+A+n+ + KIAA0756 715 eedqfqpgvwhdhskypgsvnsAVLR-LSPY----VNYQFRVIAINE--V 757 Geg<-* G++ KIAA0756 758 GSS 760 SM00060: domain 2 of 4, from 777 to 859: score 35.6, E = 6.8e-06 *->PgpPsnptelrvtdvtststsdltsvtlsWepP............iv + P++ ++ + + ++ ++++W+p + + +++ +iv KIAA0756 777 ESNPGD---VKGEGTRKN------NMEITWTPMnatsafgpnlryIV 814 gYr.................ytltgLkPgaepwteYefrVrAvngndaGe +r++++++ ++++++++++y++ + Ye+rV+A+n+ G KIAA0756 815 KWRrretreawnnvtvwgsrYVVGQTPVY----VPYEIRVQAEND--FGK 858 g<-* g KIAA0756 859 G 859 SM00060: domain 3 of 4, from 875 to 966: score 28.9, E = 0.00072 *->PgpPsnptelrvtdvtststsdltsvtlsWepP............iv +P+ ++v+ +st ++l+W++ +++ + +++ KIAA0756 875 RAAPTE---VKVRVMNST------AISLQWNRVysdtvqgqlreyRA 912 gYr..........................ytltgLkPgaepwteYefrVr +Y+++++ ++ ++++++++ + ++++ + +++ L P+ ++Y+ + KIAA0756 913 YYWressllknlwvsqkrqqasfpgdrlrGVVSRLFPY----SNYKLEMV 958 AvngndaGeg<-* +vng +G g KIAA0756 959 VVNG--RGDG 966 SM00060: domain 4 of 4, from 981 to 1065: score 36.7, E = 3.1e-06 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... P++P++ +rv+ + +++l+W++P+++++ +gY+ + KIAA0756 981 PSAPRR---FRVRQPNLE------TINLEWDHPehpngiMIGYTlky 1018 ......................ytltgLkPgaepwteYefrVrAvngnda + ++++++++ +++ +++++++t+ P ++Y+f+++A++ + KIAA0756 1019 vafngtkvgkqivenfspnqtkFTVQRTDPV----SRYRFTLSARTQ--V 1062 Geg<-* G+g KIAA0756 1063 GSG 1065 //