hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-12524313/chunk_1/iprscan-20080502-12524313.nocrc
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query sequence: KIAA0781
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       342.8   5.2e-100   1
PF00069.15.fs Protein kinase domain                       340.9    1.9e-99   1
PF07714.7.fs Protein tyrosine kinase                     103.1    7.9e-30   1
PF07714.7.ls Protein tyrosine kinase                      89.1    1.3e-23   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1      44   295 ..     1   287 []   340.9  1.9e-99
PF07714.7.fs   1/1      44   186 ..     1   158 [.   103.1  7.9e-30
PF00069.15.ls   1/1      44   295 ..     1   287 []   342.8 5.2e-100
PF07714.7.ls   1/1      44   296 ..     1   272 []    89.1  1.3e-23

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 44 to 295: score 340.9, E = 1.9e-99
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y ++++lG+G+f++V++++h+ t  +VA+Kii+k+  +   ++   r
    KIAA0781    44    YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYR 90   

                   lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse
                     E+qi+k+L+Hp+I++l+ v+e+k+ lylV+Ey+ +G    + fdyl  
    KIAA0781    91 --EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG----EIFDYLA- 133  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv
                     ++g+l   e ea++ ++Qil++++Y+H ++i+HRDLK eN+Lldnn++
    KIAA0781   134 --NHGRL--NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMN 179  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFG+  +   +s++ l t +G+p+Y+APEv  g+++ g+  D
    KIAA0781   180 I----KIADFGFGNF--FkSGElLATWCGSPPYAAPEVFEGQQYEGPQLD 223  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +WS+Gv+ly l++G +PF+g      +   l +++l+++++++++ +   
    KIAA0781   224 IWSMGVVLYVLVCGALPFDGP-----TLPILRQRVLEGRFRIPYFMS--- 265  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                               e++ +Li+++L +DPskRlt+++i++H+w+   
    KIAA0781   266 ------------EDCEHLIRRMLVLDPSKRLTIAQIKEHKWM    295  

PF07714.7.fs: domain 1 of 1, from 44 to 186: score 103.1, E = 7.9e-30
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                        +  +LG+G+F +V +G+ +     t+++VA+K+++k  + +  + 
    KIAA0781    44    YDIEGTLGKGNFAVVKLGRHR----ITKTEVAIKIIdKS-QLDAVN- 84   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +e+  rE++iMk l dHp+i++L+ v    +      ly+VtEy+++G 
    KIAA0781    85 -LEKIYREVQIMKML-DHPHIIKLYQVMET-KSM----LYLVTEYAKNGE 127  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                     d+L +h   ++L+ ++     +Qi ++ +Y + +++vHRDL A N L+
    KIAA0781   128 IFDYLANH---GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL 174  

                   senlvVKIsDFG<-*
                   ++n+ +KI+DFG   
    KIAA0781   175 DNNMNIKIADFG    186  

PF00069.15.ls: domain 1 of 1, from 44 to 295: score 342.8, E = 5.2e-100
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      y ++++lG+G+f++V++++h+ t  +VA+Kii+k+  +   ++   r
    KIAA0781    44    YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYR 90   

                   lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse
                     E+qi+k+L+Hp+I++l+ v+e+k+ lylV+Ey+ +G    + fdyl  
    KIAA0781    91 --EVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNG----EIFDYLA- 133  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv
                     ++g+l   e ea++ ++Qil++++Y+H ++i+HRDLK eN+Lldnn++
    KIAA0781   134 --NHGRL--NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMN 179  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFG+  +   +s++ l t +G+p+Y+APEv  g+++ g+  D
    KIAA0781   180 I----KIADFGFGNF--FkSGElLATWCGSPPYAAPEVFEGQQYEGPQLD 223  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +WS+Gv+ly l++G +PF+g      +   l +++l+++++++++ +   
    KIAA0781   224 IWSMGVVLYVLVCGALPFDGP-----TLPILRQRVLEGRFRIPYFMS--- 265  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                               e++ +Li+++L +DPskRlt+++i++H+w+   
    KIAA0781   266 ------------EDCEHLIRRMLVLDPSKRLTIAQIKEHKWM    295  

PF07714.7.ls: domain 1 of 1, from 44 to 296: score 89.1, E = 1.3e-23
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                        +  +LG+G+F +V +G+ +     t+++VA+K+++k  + +  + 
    KIAA0781    44    YDIEGTLGKGNFAVVKLGRHR----ITKTEVAIKIIdKS-QLDAVN- 84   

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +e+  rE++iMk l dHp+i++L+ v    +      ly+VtEy+++G 
    KIAA0781    85 -LEKIYREVQIMKML-DHPHIIKLYQVMET-KSM----LYLVTEYAKNGE 127  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                     d+L +h   ++L+ ++     +Qi ++ +Y + +++vHRDL A N L+
    KIAA0781   128 IFDYLANH---GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL 174  

                   senlvVKIsDFGLaRdiynddyYvrkkgggklPvkWm......APEslky
                   ++n+ +KI+DFG            ++++   l   W+++++  APE++  
    KIAA0781   175 DNNMNIKIADFGFGNFF-------KSGE---LLATWCgsppyaAPEVFEG 214  

                   gkF.tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLpr
                     ++  + D+WS GV+L+ ++  G+ P + g +   + +++ e + R p 
    KIAA0781   215 QQYeGPQLDIWSMGVVLYVLVC-GALP-FDGPTLPILRQRVLEGRFRIPY 262  

                   PenCPdelYdlMlqCWaedPedRPtFsel...veeL<-*
                    +  +++  +l+++    dP++R t ++++++ + L   
    KIAA0781   263 FM--SEDCEHLIRRMLVLDPSKRLTIAQIkehKWML    296  

//