hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /db/iprscan/data/Pfam.bin
Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-13551331/chunk_1/iprscan-20080502-13551331.nocrc
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Query sequence: KIAA0817
Accession: [none]
Description: [none]
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PF01437.15.fs Plexin repeat 122.7 1.4e-39 7
PF01437.15.ls Plexin repeat 131.6 2e-36 7
PF00053.14.fs Laminin EGF-like (Domains III and V) 120.7 2.5e-34 9
PF07974.3.ls EGF-like domain 106.1 9.5e-29 8
PF07974.3.fs EGF-like domain 105.0 2e-28 8
PF01344.15.fs Kelch motif 97.9 5.3e-27 9
PF01344.15.ls Kelch motif 94.7 2.6e-25 8
PF00053.14.ls Laminin EGF-like (Domains III and V) 90.6 4.4e-24 3
PF00431.11.fs CUB domain 75.5 1.4e-22 1
PF00008.17.fs EGF-like domain 80.4 1.1e-21 8
PF00008.17.ls EGF-like domain 79.0 1.4e-20 8
PF07646.5.fs Kelch motif 74.6 2e-19 9
PF07646.5.ls Kelch motif 73.5 6.2e-19 9
PF00431.11.ls CUB domain 73.3 7.2e-19 1
PF07645.6.fs Calcium binding EGF domain 53.7 1.5e-15 5
PF07645.6.ls Calcium binding EGF domain 46.2 1e-10 2
PF02363.10.fs Cysteine rich repeat 22.9 5.8e-07 3
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
PF00431.11.ls 1/1 37 144 .. 1 116 [] 73.3 7.2e-19
PF00431.11.fs 1/1 57 144 .. 23 116 .] 75.5 1.4e-22
PF07974.3.ls 2/8 181 209 .. 1 37 [] 27.4 4.7e-05
PF01344.15.fs 2/9 285 332 .. 1 45 [] 20.7 4.8e-05
PF01344.15.ls 1/8 285 332 .. 1 45 [] 22.7 0.0012
PF01344.15.ls 4/8 454 505 .. 1 45 [] 18.4 0.023
PF01344.15.fs 4/9 454 505 .. 1 45 [] 16.4 0.00078
PF01437.15.ls 4/7 889 944 .. 1 63 [] 48.4 2.2e-11
PF01437.15.fs 4/7 889 944 .. 1 63 [] 46.6 1.2e-14
PF01437.15.fs 5/7 945 1013 .. 1 63 [] 35.4 5.4e-11
PF01437.15.ls 5/7 945 1013 .. 1 63 [] 37.2 5.1e-08
PF07645.6.ls 1/2 1014 1054 .. 1 55 [] 42.7 1.2e-09
PF07645.6.fs 2/5 1014 1054 .. 1 55 [] 40.9 1.1e-11
PF00053.14.fs 3/9 1103 1148 .. 1 59 [] 21.7 1.3e-05
PF00053.14.ls 1/3 1103 1148 .. 1 59 [] 23.4 9.2e-05
PF00053.14.ls 2/3 1151 1199 .. 1 59 [] 55.5 1.6e-13
PF00053.14.fs 4/9 1151 1199 .. 1 59 [] 53.7 6.5e-15
PF07646.5.fs 6/9 1505 1553 .. 1 54 [] 16.3 0.0014
PF01344.15.ls 5/8 1505 1553 .. 1 45 [] 19.8 0.0093
PF07646.5.ls 5/9 1505 1553 .. 1 54 [] 18.1 0.029
PF01344.15.fs 6/9 1505 1553 .. 1 45 [] 17.8 0.00032
PF01344.15.ls 6/8 1611 1662 .. 1 45 [] 9.2 0.32
PF01344.15.ls 7/8 1724 1769 .. 1 45 [] 17.0 0.043
PF01344.15.fs 8/9 1724 1763 .. 1 38 [. 18.4 0.00021
PF00053.14.ls 3/3 2193 2242 .. 1 59 [] 11.6 0.0014
PF00053.14.fs 7/9 2209 2242 .. 27 59 .] 20.6 2.5e-05
Alignments of top-scoring domains:
PF00431.11.ls: domain 1 of 1, from 37 to 144: score 73.3, E = 7.2e-19
*->CGgvl.dltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLt
C g+ + l+e++G t ++ +Y+ n +C+W+I+ap +++i L
KIAA0817 37 CKGQRqVLREAPGFVT--DGAG-NYSVNGNCEWLIEAPSPQHRILLD 80
FqdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnq
F+ +d+E C YDy+ ++DG++ +pll++ G s P++i +s
KIAA0817 81 FLFLDTE-----CTYDYLFVYDGDSPRGPLLASLSG-STRPPPIEASSGK 124
mtikFvsDssiqkrGFkaty<-*
m++ sD++ + GF+a++
KIAA0817 125 MLLHLFSDANYNLLGFNASF 144
PF00431.11.fs: domain 1 of 1, from 57 to 144: score 75.5, E = 1.4e-22
*->pYppnkeCvWtIrappgyrvisLtFqdFdlEdhdgaCgYDyVEirDG
+Y+ n +C+W+I+ap +++i L F+ +d+E C YDy+ ++DG
KIAA0817 57 NYSVNGNCEWLIEAPSPQHRILLDFLFLDTE-----CTYDYLFVYDG 98
lpssspllGrfCGgsgiPedirStsnqmtikFvsDssiqkrGFkaty<-*
++ +pll++ G s P++i +s m++ sD++ + GF+a++
KIAA0817 99 DSPRGPLLASLSG-STRPPPIEASSGKMLLHLFSDANYNLLGFNASF 144
PF07974.3.ls: domain 2 of 8, from 181 to 209: score 27.4, E = 4.7e-05
*->C...CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-*
C+ C+ hGtC sp g C C++g + G +C
KIAA0817 181 CsayCGS-HGTCASP------LGPCRCEPG----FLGRAC 209
PF01344.15.fs: domain 2 of 9, from 285 to 332: score 20.7, E = 4.8e-05
*->pRsgagvvvldgkiYviGGydg..qslnsvevYDpe.tntWtklpsm
+R+++ +v+ g + +GG +++ +n+v++++p + + W+ l+++
KIAA0817 285 ARHSHVAVAWAGSLVLMGGELAdgSLTNDVWAFSPLgRGHWELLAPP 331
p<-*
KIAA0817 332 A 332
PF01344.15.ls: domain 1 of 8, from 285 to 332: score 22.7, E = 0.0012
*->pRsgagvvvldgkiYviGGydg..qslnsvevYDpe.tntWtklpsm
+R+++ +v+ g + +GG +++ +n+v++++p + + W+ l+++
KIAA0817 285 ARHSHVAVAWAGSLVLMGGELAdgSLTNDVWAFSPLgRGHWELLAPP 331
p<-*
KIAA0817 332 A 332
PF01344.15.ls: domain 4 of 8, from 454 to 505: score 18.4, E = 0.023
*->pRsgagvvvldgkiYviGGydg.......qslnsvevYDpetntWtk
R+++++ vl++++ v GG ++ ++++ + + ++ Y++ ++W
KIAA0817 454 ERAFHTASVLGNYMVVYGGNVHthyqeekCYEDGIFFYHLGCHQWVS 500
lpsmp<-*
++++
KIAA0817 501 GAELA 505
PF01344.15.fs: domain 4 of 9, from 454 to 505: score 16.4, E = 0.00078
*->pRsgagvvvldgkiYviGGydg.......qslnsvevYDpetntWtk
R+++++ vl++++ v GG ++ ++++ + + ++ Y++ ++W
KIAA0817 454 ERAFHTASVLGNYMVVYGGNVHthyqeekCYEDGIFFYHLGCHQWVS 500
lpsmp<-*
++++
KIAA0817 501 GAELA 505
PF01437.15.ls: domain 4 of 7, from 889 to 944: score 48.4, E = 2.2e-11
*->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs
Csq+ +C +CLa++ +C+WC+s+++C + +ay+ ++++g C+++
KIAA0817 889 LCSQRLTCEDCLANSS--QCAWCQSTHTCFLFAAYLaRYpHGGCRGW 933
ependqwldwswssskCp<-*
+ d+++s+ +C
KIAA0817 934 D-------DSVHSEPRCR 944
PF01437.15.fs: domain 4 of 7, from 889 to 944: score 46.6, E = 1.2e-14
*->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs
Csq+ +C +CLa++ +C+WC+s+++C + +ay+ ++++g C+++
KIAA0817 889 LCSQRLTCEDCLANSS--QCAWCQSTHTCFLFAAYLaRYpHGGCRGW 933
ependqwldwswssskCp<-*
+ d+++s+ +C
KIAA0817 934 D-------DSVHSEPRCR 944
PF01437.15.fs: domain 5 of 7, from 945 to 1013: score 35.4, E = 5.4e-11
*->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayts.....
+C ++ +C +CL++ +CgWC++++++++grC +g+ +s++ ++
KIAA0817 945 SCDGFLTCHECLQSH---ECGWCGNednptLGRCLQGD--FSgplgg 986
....f.ygeCprsependqwldwswssskCp<-*
++ ++ +ge + +l + w++++Cp
KIAA0817 987 gncsLwVGEGLGLP----VALPARWAYARCP 1013
PF01437.15.ls: domain 5 of 7, from 945 to 1013: score 37.2, E = 5.1e-08
*->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayts.....
+C ++ +C +CL++ +CgWC++++++++grC +g+ +s++ ++
KIAA0817 945 SCDGFLTCHECLQSH---ECGWCGNednptLGRCLQGD--FSgplgg 986
....f.ygeCprsependqwldwswssskCp<-*
++ ++ +ge + +l + w++++Cp
KIAA0817 987 gncsLwVGEGLGLP----VALPARWAYARCP 1013
PF07645.6.ls: domain 1 of 2, from 1014 to 1054: score 42.7, E = 1.2e-09
*->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse
DvDEC+ g + C + ++C+Nt S+eC C +GY+
KIAA0817 1014 DVDECRLGL-ARC---HPRATCLNTPLSYECH----CQRGYQ----- 1047
nnedgtnC<-*
+++ +C
KIAA0817 1048 -GDGISHC 1054
PF07645.6.fs: domain 2 of 5, from 1014 to 1054: score 40.9, E = 1.1e-11
*->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse
DvDEC+ g + C + ++C+Nt S+eC C +GY+
KIAA0817 1014 DVDECRLGL-ARC---HPRATCLNTPLSYECH----CQRGYQ----- 1047
nnedgtnC<-*
+++ +C
KIAA0817 1048 -GDGISHC 1054
PF00053.14.fs: domain 3 of 9, from 1103 to 1148: score 21.7, E = 1.3e-05
*->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
C C+ h+ +C + G C+ C++ + G++C+rC+pG
KIAA0817 1103 CGCSFHS-----HCRK------RGPGFCDECQDWTWGEHCERCRPGS 1138
yglpsgdpgqgC<-*
+g+++ +++ gC
KIAA0817 1139 FGNAT-GSR-GC 1148
PF00053.14.ls: domain 1 of 3, from 1103 to 1148: score 23.4, E = 9.2e-05
*->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
C C+ h+ +C + G C+ C++ + G++C+rC+pG
KIAA0817 1103 CGCSFHS-----HCRK------RGPGFCDECQDWTWGEHCERCRPGS 1138
yglpsgdpgqgC<-*
+g+++ +++ gC
KIAA0817 1139 FGNAT-GSR-GC 1148
PF00053.14.ls: domain 2 of 3, from 1151 to 1199: score 55.5, E = 1.6e-13
*->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
C+Cn+hG++ +++Cd +G C C+++++G +C C pGy
KIAA0817 1151 CQCNGHGDPRRGHCDN-------LSGLCF-CQDHTEGAHCQLCSPGY 1189
yglpsgdpgqgC<-*
yg+p+ g +C
KIAA0817 1190 YGDPR-AGG-SC 1199
PF00053.14.fs: domain 4 of 9, from 1151 to 1199: score 53.7, E = 6.5e-15
*->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
C+Cn+hG++ +++Cd +G C C+++++G +C C pGy
KIAA0817 1151 CQCNGHGDPRRGHCDN-------LSGLCF-CQDHTEGAHCQLCSPGY 1189
yglpsgdpgqgC<-*
yg+p+ g +C
KIAA0817 1190 YGDPR-AGG-SC 1199
PF07646.5.fs: domain 6 of 9, from 1505 to 1553: score 16.3, E = 0.0014
*->pryphasvvp...ggklyvvGGsfkgnrgtgngdesssdllvldpet
pr+ ha++ ++ ++g +y+ GG + +++d++vl++ t
KIAA0817 1505 PRSFHAAAYVpagRGAMYLLGGL--------TAGGVTRDFWVLNLTT 1543
nvWeklpalp<-*
+W+ +a+
KIAA0817 1544 LQWRQEKAPQ 1553
PF01344.15.ls: domain 5 of 8, from 1505 to 1553: score 19.8, E = 0.0093
*->pRsgagvvvl...dgkiYviGGydg.qslnsvevYDpetntWtklps
pRs++++++++ + g +Y GG + + +++++v++++t +W++
KIAA0817 1505 PRSFHAAAYVpagRGAMYLLGGLTAgGVTRDFWVLNLTTLQWRQEKA 1551
mp<-*
++
KIAA0817 1552 PQ 1553
PF07646.5.ls: domain 5 of 9, from 1505 to 1553: score 18.1, E = 0.029
*->pryphasvvp...ggklyvvGGsfkgnrgtgngdesssdllvldpet
pr+ ha++ ++ ++g +y+ GG + +++d++vl++ t
KIAA0817 1505 PRSFHAAAYVpagRGAMYLLGGL--------TAGGVTRDFWVLNLTT 1543
nvWeklpalp<-*
+W+ +a+
KIAA0817 1544 LQWRQEKAPQ 1553
PF01344.15.fs: domain 6 of 9, from 1505 to 1553: score 17.8, E = 0.00032
*->pRsgagvvvl...dgkiYviGGydg.qslnsvevYDpetntWtklps
pRs++++++++ + g +Y GG + + +++++v++++t +W++
KIAA0817 1505 PRSFHAAAYVpagRGAMYLLGGLTAgGVTRDFWVLNLTTLQWRQEKA 1551
mp<-*
++
KIAA0817 1552 PQ 1553
PF01344.15.ls: domain 6 of 8, from 1611 to 1662: score 9.2, E = 0.32
*->pRsgagvvvld..gkiYviGGydg.....qslnsvevYDpetntWtk
+g+++v+++ ++ +Yv+GG+ + + ++ +++++ + tW+
KIAA0817 1611 GLYGHSAVYHEatDSLYVFGGFRFhvelaAPSPELYSLHCPDRTWSL 1657
lpsmp<-*
l++ +
KIAA0817 1658 LAPSQ 1662
PF01344.15.ls: domain 7 of 8, from 1724 to 1769: score 17.0, E = 0.043
*->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntWtklpsmp
pR +++++ l++ + v GG++++++++++v Y + n W lp+++
KIAA0817 1724 PRLFHASALLGDTMVVLGGRSDpdEFSSDVLLYQVNCNAW-LLPDLT 1769
<-*
KIAA0817 - -
PF01344.15.fs: domain 8 of 9, from 1724 to 1763: score 18.4, E = 0.00021
*->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntW<-*
pR +++++ l++ + v GG++++++++++v Y + n W
KIAA0817 1724 PRLFHASALLGDTMVVLGGRSDpdEFSSDVLLYQVNCNAW 1763
PF00053.14.ls: domain 3 of 3, from 2193 to 2242: score 11.6, E = 0.0014
*->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
C Cn h+ +C + +Cl C+ ++ G +C++C+p +
KIAA0817 2193 CRCNRHS-----ECAG-----VGARDHCLLCRNHTKGSHCEQCLPLF 2229
yglpsg.dpgqgC<-*
g + g++ ++ C
KIAA0817 2230 VGSAVGgGTCRPC 2242
PF00053.14.fs: domain 7 of 9, from 2209 to 2242: score 20.6, E = 2.5e-05
*->qClkCkpnvtGrrCdrCkpGyyglpsg.dpgqgC<-*
+Cl C+ ++ G +C++C+p + g + g++ ++ C
KIAA0817 2209 HCLLCRNHTKGSHCEQCLPLFVGSAVGgGTCRPC 2242
//