hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-13551331/chunk_1/iprscan-20080502-13551331.nocrc
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Query sequence: KIAA0817
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF01437.15.fs Plexin repeat                               122.7    1.4e-39   7
PF01437.15.ls Plexin repeat                               131.6      2e-36   7
PF00053.14.fs Laminin EGF-like (Domains III and V)        120.7    2.5e-34   9
PF07974.3.ls EGF-like domain                             106.1    9.5e-29   8
PF07974.3.fs EGF-like domain                             105.0      2e-28   8
PF01344.15.fs Kelch motif                                  97.9    5.3e-27   9
PF01344.15.ls Kelch motif                                  94.7    2.6e-25   8
PF00053.14.ls Laminin EGF-like (Domains III and V)         90.6    4.4e-24   3
PF00431.11.fs CUB domain                                   75.5    1.4e-22   1
PF00008.17.fs EGF-like domain                              80.4    1.1e-21   8
PF00008.17.ls EGF-like domain                              79.0    1.4e-20   8
PF07646.5.fs Kelch motif                                  74.6      2e-19   9
PF07646.5.ls Kelch motif                                  73.5    6.2e-19   9
PF00431.11.ls CUB domain                                   73.3    7.2e-19   1
PF07645.6.fs Calcium binding EGF domain                   53.7    1.5e-15   5
PF07645.6.ls Calcium binding EGF domain                   46.2      1e-10   2
PF02363.10.fs Cysteine rich repeat                         22.9    5.8e-07   3

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00431.11.ls   1/1      37   144 ..     1   116 []    73.3  7.2e-19
PF00431.11.fs   1/1      57   144 ..    23   116 .]    75.5  1.4e-22
PF07974.3.ls   2/8     181   209 ..     1    37 []    27.4  4.7e-05
PF01344.15.fs   2/9     285   332 ..     1    45 []    20.7  4.8e-05
PF01344.15.ls   1/8     285   332 ..     1    45 []    22.7   0.0012
PF01344.15.ls   4/8     454   505 ..     1    45 []    18.4    0.023
PF01344.15.fs   4/9     454   505 ..     1    45 []    16.4  0.00078
PF01437.15.ls   4/7     889   944 ..     1    63 []    48.4  2.2e-11
PF01437.15.fs   4/7     889   944 ..     1    63 []    46.6  1.2e-14
PF01437.15.fs   5/7     945  1013 ..     1    63 []    35.4  5.4e-11
PF01437.15.ls   5/7     945  1013 ..     1    63 []    37.2  5.1e-08
PF07645.6.ls   1/2    1014  1054 ..     1    55 []    42.7  1.2e-09
PF07645.6.fs   2/5    1014  1054 ..     1    55 []    40.9  1.1e-11
PF00053.14.fs   3/9    1103  1148 ..     1    59 []    21.7  1.3e-05
PF00053.14.ls   1/3    1103  1148 ..     1    59 []    23.4  9.2e-05
PF00053.14.ls   2/3    1151  1199 ..     1    59 []    55.5  1.6e-13
PF00053.14.fs   4/9    1151  1199 ..     1    59 []    53.7  6.5e-15
PF07646.5.fs   6/9    1505  1553 ..     1    54 []    16.3   0.0014
PF01344.15.ls   5/8    1505  1553 ..     1    45 []    19.8   0.0093
PF07646.5.ls   5/9    1505  1553 ..     1    54 []    18.1    0.029
PF01344.15.fs   6/9    1505  1553 ..     1    45 []    17.8  0.00032
PF01344.15.ls   6/8    1611  1662 ..     1    45 []     9.2     0.32
PF01344.15.ls   7/8    1724  1769 ..     1    45 []    17.0    0.043
PF01344.15.fs   8/9    1724  1763 ..     1    38 [.    18.4  0.00021
PF00053.14.ls   3/3    2193  2242 ..     1    59 []    11.6   0.0014
PF00053.14.fs   7/9    2209  2242 ..    27    59 .]    20.6  2.5e-05

Alignments of top-scoring domains:
PF00431.11.ls: domain 1 of 1, from 37 to 144: score 73.3, E = 7.2e-19
                   *->CGgvl.dltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLt
                      C g+ + l+e++G  t  ++   +Y+ n +C+W+I+ap  +++i L 
    KIAA0817    37    CKGQRqVLREAPGFVT--DGAG-NYSVNGNCEWLIEAPSPQHRILLD 80   

                   FqdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnq
                   F+ +d+E     C YDy+ ++DG++  +pll++  G s  P++i  +s  
    KIAA0817    81 FLFLDTE-----CTYDYLFVYDGDSPRGPLLASLSG-STRPPPIEASSGK 124  

                   mtikFvsDssiqkrGFkaty<-*
                   m++   sD++ +  GF+a++   
    KIAA0817   125 MLLHLFSDANYNLLGFNASF    144  

PF00431.11.fs: domain 1 of 1, from 57 to 144: score 75.5, E = 1.4e-22
                   *->pYppnkeCvWtIrappgyrvisLtFqdFdlEdhdgaCgYDyVEirDG
                      +Y+ n +C+W+I+ap  +++i L F+ +d+E     C YDy+ ++DG
    KIAA0817    57    NYSVNGNCEWLIEAPSPQHRILLDFLFLDTE-----CTYDYLFVYDG 98   

                   lpssspllGrfCGgsgiPedirStsnqmtikFvsDssiqkrGFkaty<-*
                   ++  +pll++  G s  P++i  +s  m++   sD++ +  GF+a++   
    KIAA0817    99 DSPRGPLLASLSG-STRPPPIEASSGKMLLHLFSDANYNLLGFNASF    144  

PF07974.3.ls: domain 2 of 8, from 181 to 209: score 27.4, E = 4.7e-05
                   *->C...CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-*
                      C+  C+  hGtC sp       g C C++g    + G +C   
    KIAA0817   181    CsayCGS-HGTCASP------LGPCRCEPG----FLGRAC    209  

PF01344.15.fs: domain 2 of 9, from 285 to 332: score 20.7, E = 4.8e-05
                   *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpe.tntWtklpsm
                      +R+++ +v+  g +  +GG   +++ +n+v++++p + + W+ l+++
    KIAA0817   285    ARHSHVAVAWAGSLVLMGGELAdgSLTNDVWAFSPLgRGHWELLAPP 331  

                   p<-*
                       
    KIAA0817   332 A    332  

PF01344.15.ls: domain 1 of 8, from 285 to 332: score 22.7, E = 0.0012
                   *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpe.tntWtklpsm
                      +R+++ +v+  g +  +GG   +++ +n+v++++p + + W+ l+++
    KIAA0817   285    ARHSHVAVAWAGSLVLMGGELAdgSLTNDVWAFSPLgRGHWELLAPP 331  

                   p<-*
                       
    KIAA0817   332 A    332  

PF01344.15.ls: domain 4 of 8, from 454 to 505: score 18.4, E = 0.023
                   *->pRsgagvvvldgkiYviGGydg.......qslnsvevYDpetntWtk
                       R+++++ vl++++ v GG   ++ ++++ + + ++ Y++  ++W  
    KIAA0817   454    ERAFHTASVLGNYMVVYGGNVHthyqeekCYEDGIFFYHLGCHQWVS 500  

                   lpsmp<-*
                   ++++    
    KIAA0817   501 GAELA    505  

PF01344.15.fs: domain 4 of 9, from 454 to 505: score 16.4, E = 0.00078
                   *->pRsgagvvvldgkiYviGGydg.......qslnsvevYDpetntWtk
                       R+++++ vl++++ v GG   ++ ++++ + + ++ Y++  ++W  
    KIAA0817   454    ERAFHTASVLGNYMVVYGGNVHthyqeekCYEDGIFFYHLGCHQWVS 500  

                   lpsmp<-*
                   ++++    
    KIAA0817   501 GAELA    505  

PF01437.15.ls: domain 4 of 7, from 889 to 944: score 48.4, E = 2.2e-11
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs
                       Csq+ +C +CLa++   +C+WC+s+++C + +ay+ ++++g C+++
    KIAA0817   889    LCSQRLTCEDCLANSS--QCAWCQSTHTCFLFAAYLaRYpHGGCRGW 933  

                   ependqwldwswssskCp<-*
                   +       d+++s+ +C    
    KIAA0817   934 D-------DSVHSEPRCR    944  

PF01437.15.fs: domain 4 of 7, from 889 to 944: score 46.6, E = 1.2e-14
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsayt.sf.ygeCprs
                       Csq+ +C +CLa++   +C+WC+s+++C + +ay+ ++++g C+++
    KIAA0817   889    LCSQRLTCEDCLANSS--QCAWCQSTHTCFLFAAYLaRYpHGGCRGW 933  

                   ependqwldwswssskCp<-*
                   +       d+++s+ +C    
    KIAA0817   934 D-------DSVHSEPRCR    944  

PF01437.15.fs: domain 5 of 7, from 945 to 1013: score 35.4, E = 5.4e-11
                   *->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayts.....
                      +C ++ +C +CL++    +CgWC++++++++grC +g+  +s++ ++
    KIAA0817   945    SCDGFLTCHECLQSH---ECGWCGNednptLGRCLQGD--FSgplgg 986  

                   ....f.ygeCprsependqwldwswssskCp<-*
                   ++ ++ +ge  +       +l + w++++Cp   
    KIAA0817   987 gncsLwVGEGLGLP----VALPARWAYARCP    1013 

PF01437.15.ls: domain 5 of 7, from 945 to 1013: score 37.2, E = 5.1e-08
                   *->nCsqytsCssCLaardpfyCgWCss.....egrCtrgsayts.....
                      +C ++ +C +CL++    +CgWC++++++++grC +g+  +s++ ++
    KIAA0817   945    SCDGFLTCHECLQSH---ECGWCGNednptLGRCLQGD--FSgplgg 986  

                   ....f.ygeCprsependqwldwswssskCp<-*
                   ++ ++ +ge  +       +l + w++++Cp   
    KIAA0817   987 gncsLwVGEGLGLP----VALPARWAYARCP    1013 

PF07645.6.ls: domain 1 of 2, from 1014 to 1054: score 42.7, E = 1.2e-09
                   *->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse
                      DvDEC+ g  + C   +  ++C+Nt  S+eC     C +GY+     
    KIAA0817  1014    DVDECRLGL-ARC---HPRATCLNTPLSYECH----CQRGYQ----- 1047 

                   nnedgtnC<-*
                    +++  +C   
    KIAA0817  1048 -GDGISHC    1054 

PF07645.6.fs: domain 2 of 5, from 1014 to 1054: score 40.9, E = 1.1e-11
                   *->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse
                      DvDEC+ g  + C   +  ++C+Nt  S+eC     C +GY+     
    KIAA0817  1014    DVDECRLGL-ARC---HPRATCLNTPLSYECH----CQRGYQ----- 1047 

                   nnedgtnC<-*
                    +++  +C   
    KIAA0817  1048 -GDGISHC    1054 

PF00053.14.fs: domain 3 of 9, from 1103 to 1148: score 21.7, E = 1.3e-05
                   *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
                      C C+ h+     +C        +  G C+ C++ + G++C+rC+pG 
    KIAA0817  1103    CGCSFHS-----HCRK------RGPGFCDECQDWTWGEHCERCRPGS 1138 

                   yglpsgdpgqgC<-*
                   +g+++ +++ gC   
    KIAA0817  1139 FGNAT-GSR-GC    1148 

PF00053.14.ls: domain 1 of 3, from 1103 to 1148: score 23.4, E = 9.2e-05
                   *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
                      C C+ h+     +C        +  G C+ C++ + G++C+rC+pG 
    KIAA0817  1103    CGCSFHS-----HCRK------RGPGFCDECQDWTWGEHCERCRPGS 1138 

                   yglpsgdpgqgC<-*
                   +g+++ +++ gC   
    KIAA0817  1139 FGNAT-GSR-GC    1148 

PF00053.14.ls: domain 2 of 3, from 1151 to 1199: score 55.5, E = 1.6e-13
                   *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
                      C+Cn+hG++ +++Cd         +G C  C+++++G +C  C pGy
    KIAA0817  1151    CQCNGHGDPRRGHCDN-------LSGLCF-CQDHTEGAHCQLCSPGY 1189 

                   yglpsgdpgqgC<-*
                   yg+p+   g +C   
    KIAA0817  1190 YGDPR-AGG-SC    1199 

PF00053.14.fs: domain 4 of 9, from 1151 to 1199: score 53.7, E = 6.5e-15
                   *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
                      C+Cn+hG++ +++Cd         +G C  C+++++G +C  C pGy
    KIAA0817  1151    CQCNGHGDPRRGHCDN-------LSGLCF-CQDHTEGAHCQLCSPGY 1189 

                   yglpsgdpgqgC<-*
                   yg+p+   g +C   
    KIAA0817  1190 YGDPR-AGG-SC    1199 

PF07646.5.fs: domain 6 of 9, from 1505 to 1553: score 16.3, E = 0.0014
                   *->pryphasvvp...ggklyvvGGsfkgnrgtgngdesssdllvldpet
                      pr+ ha++ ++ ++g +y+ GG           + +++d++vl++ t
    KIAA0817  1505    PRSFHAAAYVpagRGAMYLLGGL--------TAGGVTRDFWVLNLTT 1543 

                   nvWeklpalp<-*
                    +W+  +a+    
    KIAA0817  1544 LQWRQEKAPQ    1553 

PF01344.15.ls: domain 5 of 8, from 1505 to 1553: score 19.8, E = 0.0093
                   *->pRsgagvvvl...dgkiYviGGydg.qslnsvevYDpetntWtklps
                      pRs++++++++ + g +Y  GG + +  +++++v++++t +W++   
    KIAA0817  1505    PRSFHAAAYVpagRGAMYLLGGLTAgGVTRDFWVLNLTTLQWRQEKA 1551 

                   mp<-*
                   ++   
    KIAA0817  1552 PQ    1553 

PF07646.5.ls: domain 5 of 9, from 1505 to 1553: score 18.1, E = 0.029
                   *->pryphasvvp...ggklyvvGGsfkgnrgtgngdesssdllvldpet
                      pr+ ha++ ++ ++g +y+ GG           + +++d++vl++ t
    KIAA0817  1505    PRSFHAAAYVpagRGAMYLLGGL--------TAGGVTRDFWVLNLTT 1543 

                   nvWeklpalp<-*
                    +W+  +a+    
    KIAA0817  1544 LQWRQEKAPQ    1553 

PF01344.15.fs: domain 6 of 9, from 1505 to 1553: score 17.8, E = 0.00032
                   *->pRsgagvvvl...dgkiYviGGydg.qslnsvevYDpetntWtklps
                      pRs++++++++ + g +Y  GG + +  +++++v++++t +W++   
    KIAA0817  1505    PRSFHAAAYVpagRGAMYLLGGLTAgGVTRDFWVLNLTTLQWRQEKA 1551 

                   mp<-*
                   ++   
    KIAA0817  1552 PQ    1553 

PF01344.15.ls: domain 6 of 8, from 1611 to 1662: score 9.2, E = 0.32
                   *->pRsgagvvvld..gkiYviGGydg.....qslnsvevYDpetntWtk
                        +g+++v+++ ++ +Yv+GG+  + +   ++   +++++ + tW+ 
    KIAA0817  1611    GLYGHSAVYHEatDSLYVFGGFRFhvelaAPSPELYSLHCPDRTWSL 1657 

                   lpsmp<-*
                   l++ +   
    KIAA0817  1658 LAPSQ    1662 

PF01344.15.ls: domain 7 of 8, from 1724 to 1769: score 17.0, E = 0.043
                   *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntWtklpsmp
                      pR +++++ l++ + v GG++++++++++v  Y +  n W  lp+++
    KIAA0817  1724    PRLFHASALLGDTMVVLGGRSDpdEFSSDVLLYQVNCNAW-LLPDLT 1769 

                   <-*
                      
    KIAA0817     -     -    

PF01344.15.fs: domain 8 of 9, from 1724 to 1763: score 18.4, E = 0.00021
                   *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntW<-*
                      pR +++++ l++ + v GG++++++++++v  Y +  n W   
    KIAA0817  1724    PRLFHASALLGDTMVVLGGRSDpdEFSSDVLLYQVNCNAW    1763 

PF00053.14.ls: domain 3 of 3, from 2193 to 2242: score 11.6, E = 0.0014
                   *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy
                      C Cn h+     +C        +   +Cl C+ ++ G +C++C+p +
    KIAA0817  2193    CRCNRHS-----ECAG-----VGARDHCLLCRNHTKGSHCEQCLPLF 2229 

                   yglpsg.dpgqgC<-*
                    g + g++ ++ C   
    KIAA0817  2230 VGSAVGgGTCRPC    2242 

PF00053.14.fs: domain 7 of 9, from 2209 to 2242: score 20.6, E = 2.5e-05
                   *->qClkCkpnvtGrrCdrCkpGyyglpsg.dpgqgC<-*
                      +Cl C+ ++ G +C++C+p + g + g++ ++ C   
    KIAA0817  2209    HCLLCRNHTKGSHCEQCLPLFVGSAVGgGTCRPC    2242 

//