hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-15192250/chunk_1/iprscan-20080501-15192250.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1027 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00373.8.fs FERM domain (Band 4.1 family) 364.2 1.3e-113 1 PF09141.1.fs Talin, middle domain 368.5 1.9e-113 1 PF01608.8.fs I/LWEQ domain 381.5 1.2e-111 4 PF01608.8.ls I/LWEQ domain 371.9 9.3e-109 1 PF09141.1.ls Talin, middle domain 370.4 2.6e-108 1 PF00373.8.ls FERM domain (Band 4.1 family) 366.1 5.3e-107 1 PF08913.1.fs Vinculin Binding Site 292.2 9.1e-85 2 PF08913.1.ls Vinculin Binding Site 288.7 1e-83 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00373.8.ls 1/1 130 322 .. 1 210 [] 366.1 5.3e-107 PF00373.8.fs 1/1 130 322 .. 1 210 [] 364.2 1.3e-113 PF09141.1.ls 1/1 500 661 .. 1 164 [] 370.4 2.6e-108 PF09141.1.fs 1/1 500 661 .. 1 164 [] 368.5 1.9e-113 PF08913.1.fs 1/2 1243 1352 .. 1 110 [. 5.5 0.34 PF08913.1.fs 2/2 1858 1982 .. 1 125 [] 286.7 4e-83 PF08913.1.ls 1/1 1858 1982 .. 1 125 [] 288.7 1e-83 PF01608.8.fs 4/4 2350 2542 .. 1 202 [] 370.0 3.4e-108 PF01608.8.ls 1/1 2350 2542 .. 1 202 [] 371.9 9.3e-109 Alignments of top-scoring domains: PF00373.8.ls: domain 1 of 1, from 130 to 322: score 366.1, E = 5.3e-107 *->ctvtllDstveeFkveKkdkGqvLLdkVfkhLglrEkdYFGLQylDd +t+++++s+v+e+++eKk + +++L+k++++L++++k+++++Q+l+ KIAA1027 130 ITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLH- 175 DnsskdsptWLdpsKkirkQdvkkeePytLhFRvKFYpeDvpneLrqeiT ++d+++WLd+++++r+Q ++ee++tL++R+KF+++D+++++r++++ KIAA1027 176 ---TDDELNWLDHGRTLREQ--GVEEHETLLLRRKFFYSDQNVDSRDPVQ 220 rylffLQvkqdIleGrlpCpfetAvLLASYaVQsefGDYneslHkaGRtC ++l+++Q+++dIl+G++p++f++A+++A++++Q++fG++ne++HkaG KIAA1027 221 LNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAG--- 267 LCYLsdekllPqRVlnqkqltkddfEekIaelHkeHrGmspdeAeleYLk +L+++++lP k+++k+++E+kI+++Hk++++ms++eA+++Y+k KIAA1027 268 --FLDLKDFLP------KEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVK 309 iArdLemYGVdff<-* +Ar+L++YGV+ff KIAA1027 310 LARSLKTYGVSFF 322 PF00373.8.fs: domain 1 of 1, from 130 to 322: score 364.2, E = 1.3e-113 *->ctvtllDstveeFkveKkdkGqvLLdkVfkhLglrEkdYFGLQylDd +t+++++s+v+e+++eKk + +++L+k++++L++++k+++++Q+l+ KIAA1027 130 ITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLH- 175 DnsskdsptWLdpsKkirkQdvkkeePytLhFRvKFYpeDvpneLrqeiT ++d+++WLd+++++r+Q ++ee++tL++R+KF+++D+++++r++++ KIAA1027 176 ---TDDELNWLDHGRTLREQ--GVEEHETLLLRRKFFYSDQNVDSRDPVQ 220 rylffLQvkqdIleGrlpCpfetAvLLASYaVQsefGDYneslHkaGRtC ++l+++Q+++dIl+G++p++f++A+++A++++Q++fG++ne++HkaG KIAA1027 221 LNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAG--- 267 LCYLsdekllPqRVlnqkqltkddfEekIaelHkeHrGmspdeAeleYLk +L+++++lP k+++k+++E+kI+++Hk++++ms++eA+++Y+k KIAA1027 268 --FLDLKDFLP------KEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVK 309 iArdLemYGVdff<-* +Ar+L++YGV+ff KIAA1027 310 LARSLKTYGVSFF 322 PF09141.1.ls: domain 1 of 1, from 500 to 661: score 370.4, E = 2.6e-108 *->pQrALlGtIsasqdAvqrAeeeLeakeqiDlPpLGdDlssnrWrenk +Q+AL+GtI++s++Avq+A+++L+++ + lPpLG+D++s++Wr+nk KIAA1027 500 AQQALTGTINSSMQAVQAAQATLDDFDT--LPPLGQDAASKAWRKNK 544 lDtSKqnvhsqvaamtAATAqVVnlTAsdPdevDyeaVGaAvstIssnlp +D+SK+++hsqv+a+tA+TA+VVnlTA+dP+e+Dy+aVG+Av+tIssnl+ KIAA1027 545 MDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLT 594 EvskeVrLlAALMEddvGsGddLLeAarkLcgAfSdLLkaaePeSkePRq E+s++V+LlAAL+Ed++GsG++LL+Aa++L+gA+S+LL++a+P+S+ePRq KIAA1027 595 EMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQ 644 nllnAAgrVGeASghlL<-* nll+AAg+VG+ASg+lL KIAA1027 645 NLLQAAGNVGQASGELL 661 PF09141.1.fs: domain 1 of 1, from 500 to 661: score 368.5, E = 1.9e-113 *->pQrALlGtIsasqdAvqrAeeeLeakeqiDlPpLGdDlssnrWrenk +Q+AL+GtI++s++Avq+A+++L+++ + lPpLG+D++s++Wr+nk KIAA1027 500 AQQALTGTINSSMQAVQAAQATLDDFDT--LPPLGQDAASKAWRKNK 544 lDtSKqnvhsqvaamtAATAqVVnlTAsdPdevDyeaVGaAvstIssnlp +D+SK+++hsqv+a+tA+TA+VVnlTA+dP+e+Dy+aVG+Av+tIssnl+ KIAA1027 545 MDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLT 594 EvskeVrLlAALMEddvGsGddLLeAarkLcgAfSdLLkaaePeSkePRq E+s++V+LlAAL+Ed++GsG++LL+Aa++L+gA+S+LL++a+P+S+ePRq KIAA1027 595 EMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQ 644 nllnAAgrVGeASghlL<-* nll+AAg+VG+ASg+lL KIAA1027 645 NLLQAAGNVGQASGELL 661 PF08913.1.fs: domain 1 of 2, from 1243 to 1352: score 5.5, E = 0.34 *->tFVDYQTrMVkyaKaIAvtAqEMvtKsvtnPeeLgqLAvqlTedYgq tF ++Q r+ a A E+v s P++L+ ++ +d++ KIAA1027 1243 TFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFST 1289 LAqdsrlAaataeseeiGfrIktrVqdLGhscivlVqkAGalqisPnDsy + ++ a+ a+s+e ++ s + l A al P KIAA1027 1290 FLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPN 1339 tkreLiecAReVs<-* k +L+ AR+V+ KIAA1027 1340 LKSQLAAAARAVT 1352 PF08913.1.fs: domain 2 of 2, from 1858 to 1982: score 286.7, E = 4e-83 *->tFVDYQTrMVkyaKaIAvtAqEMvtKsvtnPeeLgqLAvqlTedYgq +FVDYQT+MV++aKaIAvt+qEMvtKs+t+PeeLg LA+qlT+dYg+ KIAA1027 1858 SFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGR 1904 LAqdsrlAaataeseeiGfrIktrVqdLGhscivlVqkAGalqisPnDsy LA+++++Aa+ ae+eeiG++Ik+rVq+LGh+c++lV+kAGalq+sP+D+y KIAA1027 1905 LASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAY 1954 tkreLiecAReVsEKVsqVLAALqAGsR<-* tk+eLiecAR+VsEKVs+VLAALqAG+R KIAA1027 1955 TKKELIECARRVSEKVSHVLAALQAGNR 1982 PF08913.1.ls: domain 1 of 1, from 1858 to 1982: score 288.7, E = 1e-83 *->tFVDYQTrMVkyaKaIAvtAqEMvtKsvtnPeeLgqLAvqlTedYgq +FVDYQT+MV++aKaIAvt+qEMvtKs+t+PeeLg LA+qlT+dYg+ KIAA1027 1858 SFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGR 1904 LAqdsrlAaataeseeiGfrIktrVqdLGhscivlVqkAGalqisPnDsy LA+++++Aa+ ae+eeiG++Ik+rVq+LGh+c++lV+kAGalq+sP+D+y KIAA1027 1905 LASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAY 1954 tkreLiecAReVsEKVsqVLAALqAGsR<-* tk+eLiecAR+VsEKVs+VLAALqAG+R KIAA1027 1955 TKKELIECARRVSEKVSHVLAALQAGNR 1982 PF01608.8.fs: domain 4 of 4, from 2350 to 2542: score 370.0, E = 3.4e-108 *->VnesILsaakaImkAiaaLVkAAsaaQrEivaqGrgsaspaefYkkn ++e+IL+aak+I++A++aLVkAAsaaQrE+vaqG+++a+pa++++ + KIAA1027 2350 FEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALD-D 2395 srWTEGLISAAKaVgaAttvLvEAAdkvVtsEDnGkgsfEeLIVaakeVA ++W++GLISAA++V+aAt++L+EAA+++V+ G++s+E+LI++ak+VA KIAA1027 2396 GQWSQGLISAARMVAAATNNLCEAANAAVQ----GHASQEKLISSAKQVA 2441 ASTAQLVaASrVKAGDDkdSkaAldrLqaAakaVneAtanLVaaaksgai ASTAQL++A++VKA D+dS+a ++rLqaA++aV++A++nLV+aa+++a+ KIAA1027 2442 ASTAQLLVACKVKA--DQDSEA-MKRLQAAGNAVKRASDNLVKAAQKAAA 2488 fdiedqqeedfsslslhglKaqEmEqQveiLkLEkeLeeARkkLaelRKq f+ e+++e+++++++++g++aq++++Q+e+L++E+eLeeARkkLa++R+q KIAA1027 2489 FE-EQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQ 2537 hYela<-* +Y++ KIAA1027 2538 QYKFL 2542 PF01608.8.ls: domain 1 of 1, from 2350 to 2542: score 371.9, E = 9.3e-109 *->VnesILsaakaImkAiaaLVkAAsaaQrEivaqGrgsaspaefYkkn ++e+IL+aak+I++A++aLVkAAsaaQrE+vaqG+++a+pa++++ + KIAA1027 2350 FEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALD-D 2395 srWTEGLISAAKaVgaAttvLvEAAdkvVtsEDnGkgsfEeLIVaakeVA ++W++GLISAA++V+aAt++L+EAA+++V+ G++s+E+LI++ak+VA KIAA1027 2396 GQWSQGLISAARMVAAATNNLCEAANAAVQ----GHASQEKLISSAKQVA 2441 ASTAQLVaASrVKAGDDkdSkaAldrLqaAakaVneAtanLVaaaksgai ASTAQL++A++VKA D+dS+a ++rLqaA++aV++A++nLV+aa+++a+ KIAA1027 2442 ASTAQLLVACKVKA--DQDSEA-MKRLQAAGNAVKRASDNLVKAAQKAAA 2488 fdiedqqeedfsslslhglKaqEmEqQveiLkLEkeLeeARkkLaelRKq f+ e+++e+++++++++g++aq++++Q+e+L++E+eLeeARkkLa++R+q KIAA1027 2489 FE-EQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQ 2537 hYela<-* +Y++ KIAA1027 2538 QYKFL 2542 //