HUGE

Gene/Protein Characteristic Table for KIAA1048

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00722
Accession No. :	AB028971
Description :	AP2-associated protein kinase 1.
HUGO Gene Name :	AP2 associated kinase 1 (AAK1)
Clone Name :	hh02560 [Vector Info]
Flexi ORF Clone :	pF1KSDA1048
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4506 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 1530 bp

Genome contig ID gi89161199r_69461797
PolyA signal sequence
(None)
+----*----+----*----+----*----+----
TCAGGAGCAAGACACCATCTCAAAAAATGAGAATT
Flanking genome sequence
(99895 - 99846)
----+----*----+----*----+----*----+----*----+----*
AAAAAAAAAGAAGAAAGCTTCACAGAATTTCCTAAAGAAACTTCTGACTC

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 2 r 69561692 69724353 18 99.0 Perfect prediction

Features of the protein sequence	Description

Length: 897 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
AAI04843	7.5e-199	100.0	AP2 associated ...	Homo sapiens
Q2M2I8	1.1e-198	99.9	AP2-associated ...	Homo sapiens
EAW99847	3.6e-198	99.9	AP2 associated ...	Homo sapiens
AAI43711	9.5e-198	99.8	Unknown (protei...	Homo sapiens
XP_001138187	1.4e-197	99.5	AP2 associated ...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR000719 80 336 PD000001 Protein kinase

HMMPfam IPR000719 80 344 PF00069 Protein kinase

HMMSmart IPR001245 80 346 SM00219 Tyrosine protein kinase

IPR002290 80 347 SM00220 Serine/threonine protein kinase

ProfileScan IPR000719 80 349 PS50011 Protein kinase

ScanRegExp IPR008271 206 218 PS00108 Serine/threonine protein kinase

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR000719	80	336	PD000001	Protein kinase
HMMPfam	IPR000719	80	344	PF00069	Protein kinase
HMMSmart	IPR001245	80	346	SM00219	Tyrosine protein kinase
IPR002290	80	347	SM00220	Serine/threonine protein kinase
ProfileScan	IPR000719	80	349	PS50011	Protein kinase
ScanRegExp	IPR008271	206	218	PS00108	Serine/threonine protein kinase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 275 TKADIWALGCLLYKLCYFTLPF 296 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	275	TKADIWALGCLLYKLCYFTLPF	296	PRIMARY	22

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AGATGGATTAATGGCCTTTGC

Primer_r
: ACATAAGCCGCTCAGCAAACC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 2

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: AGATGGATTAATGGCCTTTGC
Primer_r	: ACATAAGCCGCTCAGCAAACC
PCR product length	: 144 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	1530 bp
Genome contig ID	gi89161199r_69461797
PolyA signal sequence (None)	+--------+--------+----*----+---- TCAGGAGCAAGACACCATCTCAAAAAATGAGAATT
Flanking genome sequence (99895 - 99846)	----+--------+--------+--------+--------+----* AAAAAAAAAGAAGAAAGCTTCACAGAATTTCCTAAAGAAACTTCTGACTC

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	2	r	69561692	69724353	18	99.0	Perfect prediction

Gene/Protein Characteristic Table for KIAA1048

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information