hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080501/iprscan-20080501-16473439/chunk_1/iprscan-20080501-16473439.nocrc
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Query sequence: KIAA1079
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF07714.7.fs Protein tyrosine kinase                     165.1    8.5e-48   1
PF07714.7.ls Protein tyrosine kinase                     166.9    4.7e-47   1
PF00069.15.ls Protein kinase domain                        34.6    1.2e-10   1
PF00069.15.fs Protein kinase domain                        35.9    4.5e-10   2

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/2     159   308 ..     1   159 [.    33.9  1.7e-09
PF07714.7.fs   1/1     159   429 ..     1   272 []   165.1  8.5e-48
PF00069.15.ls   1/1     159   429 ..     1   287 []    34.6  1.2e-10
PF07714.7.ls   1/1     159   429 ..     1   272 []   166.9  4.7e-47

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 2, from 159 to 308: score 33.9, E = 1.7e-09
                   *->yelleklGsGsfGtVykakhkgtgk...iVAvKiikkrkekskkdkt
                      +  ++ +G G fG+V ++ ++ tg +  +V vK++k + + +++d  
    KIAA1079   159    LNYIQEIGNGWFGKVLLG-EIYTGTsvaRVIVKELKASANPKEQDTF 204  

                   arrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdy
                   + +  E ++   L+HpNI+++ + + +   + lV+E+c+ G    dL++y
    KIAA1079   205 LKNG-EPYYI--LQHPNILQCVGQCVEAIPYLLVFEFCDLG----DLKAY 247  

                   ls.e.trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILl
                   l++e+ +++g    +   ++++a +++ gl+ +H+  ++H DL + N++l
    KIAA1079   248 LRsEqEHMRGDS--QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFL 295  

                   dnngvvdaflKiaDFGl<-*
                    ++ +v    K++D G+   
    KIAA1079   296 TSDLNV----KVGDYGI    308  

PF07714.7.fs: domain 1 of 1, from 159 to 429: score 165.1, E = 8.5e-48
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie
                      l  ++++G G FG+V +G+ +   +     V VK Lk  +a ++e  
    KIAA1079   159    LNYIQEIGNGWFGKVLLGEIY--TGTSVARVIVKELKA-SANPKE-- 200  

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                   ++ Fl+  +    l +HpNi+++ G c++   P    +++V+E++ +GdL
    KIAA1079   201 QDTFLKNGEPYYIL-QHPNILQCVGQCVE-AIP----YLLVFEFCDLGDL 244  

                   ldfLrkhregrpL....tlkdLlsfalQiAkGMeYLesknfvHRDLAARN
                   + +Lr+   +++ ++++ +  L  +a ++A+G++  +  +f H DLA RN
    KIAA1079   245 KAYLRSE--QEHMrgdsQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRN 292  

                   cLVsenlvVKIsDFGL..aRdiynddyYvrkkgggk.lPvkWmAPEslky
                   c ++++l VK++D G + +R+    + Y   +++ k +P +W+APE    
    KIAA1079   293 CFLTSDLNVKVGDYGIgfSRYK---EDY-IETDDKKvFPLRWTAPELVTS 338  

                   gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed
                     ++  + + t  S +WS GV+LWE+f   +qP Y ++sn +vl+++  +
    KIAA1079   339 FQdrlltadQTKYSNIWSLGVTLWELFDNAAQP-YSNLSNLDVLNQV-IR 386  

                   .......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-*
                   +++++ +  +L++P   +d  Y++++ CW   Pe+RP  +++++ L   
    KIAA1079   387 erdtklpKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLL    429  

PF00069.15.ls: domain 1 of 1, from 159 to 429: score 34.6, E = 1.2e-10
                   *->yelleklGsGsfGtVykakhkgtgk...iVAvKiikkrkekskkdkt
                      +  ++ +G G fG+V ++ ++ tg +  +V vK++k + + +++d  
    KIAA1079   159    LNYIQEIGNGWFGKVLLG-EIYTGTsvaRVIVKELKASANPKEQDTF 204  

                   arrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdy
                   + +  E ++   L+HpNI+++ + + +   + lV+E+c+ G    dL++y
    KIAA1079   205 LKNG-EPYYI--LQHPNILQCVGQCVEAIPYLLVFEFCDLG----DLKAY 247  

                   ls.e.trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILl
                   l++e+ +++g    +   ++++a +++ gl+ +H+  ++H DL + N++l
    KIAA1079   248 LRsEqEHMRGDS--QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFL 295  

                   dnngvvdaflKiaDFGlAkkls.....t.sss.lttfvGTpwYmAPEv..
                    ++ +v    K++D G+   +s+ ++++    + ++f   +++ APE+ +
    KIAA1079   296 TSDLNV----KVGDYGIG--FSrykedYiETDdKKVFP--LRWTAPELvt 337  

                   .....llggngygtkvDvWSlGvilyelltGk.pPFsgevqdsldqlqli
                   + +++ll   + ++ + +WSlGv+l+el+     P+s+      + ++l 
    KIAA1079   338 sfqdrLL-TADQTKYSNIWSLGVTLWELFDNAaQPYSNL----SNLDVLN 382  

                   rkilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRlt
                   + i++++++ + p+   ++          s+   +++  c+ + P+kR+ 
    KIAA1079   383 QVIRERDTKLPKPQLEQPY----------SDRWYEVLQFCW-LSPEKRPA 421  

                   aeeilqHPwf<-*
                   ae++     +   
    KIAA1079   422 AEDVHRL--L    429  

PF07714.7.ls: domain 1 of 1, from 159 to 429: score 166.9, E = 4.7e-47
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie
                      l  ++++G G FG+V +G+ +   +     V VK Lk  +a ++e  
    KIAA1079   159    LNYIQEIGNGWFGKVLLGEIY--TGTSVARVIVKELKA-SANPKE-- 200  

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                   ++ Fl+  +    l +HpNi+++ G c++   P    +++V+E++ +GdL
    KIAA1079   201 QDTFLKNGEPYYIL-QHPNILQCVGQCVE-AIP----YLLVFEFCDLGDL 244  

                   ldfLrkhregrpL....tlkdLlsfalQiAkGMeYLesknfvHRDLAARN
                   + +Lr+   +++ ++++ +  L  +a ++A+G++  +  +f H DLA RN
    KIAA1079   245 KAYLRSE--QEHMrgdsQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRN 292  

                   cLVsenlvVKIsDFGL..aRdiynddyYvrkkgggk.lPvkWmAPEslky
                   c ++++l VK++D G + +R+    + Y   +++ k +P +W+APE    
    KIAA1079   293 CFLTSDLNVKVGDYGIgfSRYK---EDY-IETDDKKvFPLRWTAPELVTS 338  

                   gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed
                     ++  + + t  S +WS GV+LWE+f   +qP Y ++sn +vl+++  +
    KIAA1079   339 FQdrlltadQTKYSNIWSLGVTLWELFDNAAQP-YSNLSNLDVLNQV-IR 386  

                   .......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-*
                   +++++ +  +L++P   +d  Y++++ CW   Pe+RP  +++++ L   
    KIAA1079   387 erdtklpKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLL    429  

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