hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-17434567/chunk_1/iprscan-20080501-17434567.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1112 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00621.11.fs RhoGEF domain 138.6 8.8e-41 1 PF00621.11.ls RhoGEF domain 140.4 4.5e-39 1 PF00169.19.fs PH domain 50.3 7.6e-15 1 PF00018.18.fs SH3 domain 49.4 9.8e-13 1 PF00169.19.ls PH domain 52.3 1.5e-12 1 PF00018.18.ls SH3 domain 51.3 2.9e-12 1 PF07653.7.fs Variant SH3 domain 30.4 4e-08 1 PF07653.7.ls Variant SH3 domain 31.4 3e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00018.18.ls 1/1 221 275 .. 1 59 [] 51.3 2.9e-12 PF00018.18.fs 1/1 221 275 .. 1 59 [] 49.4 9.8e-13 PF07653.7.ls 1/1 222 275 .. 1 69 [] 31.4 3e-06 PF07653.7.fs 1/1 228 275 .. 7 69 .] 30.4 4e-08 PF00621.11.fs 1/1 312 491 .. 1 207 [] 138.6 8.8e-41 PF00621.11.ls 1/1 312 491 .. 1 207 [] 140.4 4.5e-39 PF00169.19.fs 1/1 524 630 .. 1 92 [] 50.3 7.6e-15 PF00169.19.ls 1/1 524 630 .. 1 92 [] 52.3 1.5e-12 Alignments of top-scoring domains: PF00018.18.ls: domain 1 of 1, from 221 to 275: score 51.3, E = 2.9e-12 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk + AL D + ++++EL Fk GDvi+v + ++ +WW gr+ + KIAA1112 221 VCAEALWDHVTMDDQELGFKAGDVIEVMDATNR-EWWWGRVA---DG 263 eGliPsNYVepv<-* eG++P+++V++ KIAA1112 264 EGWFPASFVRLR 275 PF00018.18.fs: domain 1 of 1, from 221 to 275: score 49.4, E = 9.8e-13 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk + AL D + ++++EL Fk GDvi+v + ++ +WW gr+ + KIAA1112 221 VCAEALWDHVTMDDQELGFKAGDVIEVMDATNR-EWWWGRVA---DG 263 eGliPsNYVepv<-* eG++P+++V++ KIAA1112 264 EGWFPASFVRLR 275 PF07653.7.ls: domain 1 of 1, from 222 to 275: score 31.4, E = 3e-06 *->ygraiedyvaAtdknenleeeeLslkkGdvvkVidvggskdddgwwe + a+ d+v d +e L +k+Gdv++V + + +ww+ KIAA1112 222 CAEALWDHVT-MDDQE------LGFKAGDVIEVM----DATNREWWW 257 geslggGrrrRGlvPssaveel<-* g++ + G++P+s+v+ KIAA1112 258 GRV--ADGE--GWFPASFVRLR 275 PF07653.7.fs: domain 1 of 1, from 228 to 275: score 30.4, E = 4e-08 *->dyvaAtdknenleeeeLslkkGdvvkVidvggskdddgwwegeslgg d+v d +e L +k+Gdv++V + + +ww+g++ KIAA1112 228 DHVT-MDDQE------LGFKAGDVIEVM----DATNREWWWGRV--A 261 GrrrRGlvPssaveel<-* + G++P+s+v+ KIAA1112 262 DGE--GWFPASFVRLR 275 PF00621.11.fs: domain 1 of 1, from 312 to 491: score 138.6, E = 8.8e-41 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E+l TE+ Y+++L+++ +y ++ r+ a ++ +++ tiF KIAA1112 312 VINEILSTERDYIKHLRDICEGYVRQCRKRA----DMFSEEQLRTIF 354 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+ +++F k +Le+r + p+ + lG++Fle+ KIAA1112 355 GNIEDIYRCQKAFVK-ALEQRFNRE----------RPHLSELGACFLEHQ 393 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd a+f q+Y eYc+n+p+A l++l ++ +F+e + +++ + KIAA1112 394 ADF-QIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMID----- 437 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda +L+ +Ll Pvq i++YpL L eLLk+t + + + +d ++al a KIAA1112 438 ----ISLDGFLLTPVQKICKYPLQLAELLKYTHP--QHRDFKDVEAALHA 481 lqdlaksiNe<-* ++++a+ iNe KIAA1112 482 MKNVAQLINE 491 PF00621.11.ls: domain 1 of 1, from 312 to 491: score 140.4, E = 4.5e-39 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E+l TE+ Y+++L+++ +y ++ r+ a ++ +++ tiF KIAA1112 312 VINEILSTERDYIKHLRDICEGYVRQCRKRA----DMFSEEQLRTIF 354 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+ +++F k +Le+r + p+ + lG++Fle+ KIAA1112 355 GNIEDIYRCQKAFVK-ALEQRFNRE----------RPHLSELGACFLEHQ 393 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd a+f q+Y eYc+n+p+A l++l ++ +F+e + +++ + KIAA1112 394 ADF-QIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMID----- 437 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda +L+ +Ll Pvq i++YpL L eLLk+t + + + +d ++al a KIAA1112 438 ----ISLDGFLLTPVQKICKYPLQLAELLKYTHP--QHRDFKDVEAALHA 481 lqdlaksiNe<-* ++++a+ iNe KIAA1112 482 MKNVAQLINE 491 PF00169.19.fs: domain 1 of 1, from 524 to 630: score 50.3, E = 7.6e-15 *->vikeGwLlkkg.gkkswkkRyfvLfddvLlyykdkk.....kkpkgs +i++G+L++ ++ + ++R f+Lfd +L+y+k++ +++ +kg KIAA1112 524 LIYSGELTRVTqPQAKSQQRMFFLFDHQLIYCKKDLlrrdvLYYKGR 570 ipLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerke ++++g++v++++d+++++ + kn+F+++ + ++++ll++ +e++++ KIAA1112 571 LDMDGLEVVDLEDGkdrdlhvSIKNAFRLHRgATgDSHLLCTRKPEQKQR 620 Wvkaiqsair<-* W+ka+ + KIAA1112 621 WLKAFARERE 630 PF00169.19.ls: domain 1 of 1, from 524 to 630: score 52.3, E = 1.5e-12 *->vikeGwLlkkg.gkkswkkRyfvLfddvLlyykdkk.....kkpkgs +i++G+L++ ++ + ++R f+Lfd +L+y+k++ +++ +kg KIAA1112 524 LIYSGELTRVTqPQAKSQQRMFFLFDHQLIYCKKDLlrrdvLYYKGR 570 ipLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerke ++++g++v++++d+++++ + kn+F+++ + ++++ll++ +e++++ KIAA1112 571 LDMDGLEVVDLEDGkdrdlhvSIKNAFRLHRgATgDSHLLCTRKPEQKQR 620 Wvkaiqsair<-* W+ka+ + KIAA1112 621 WLKAFARERE 630 //