hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-17550292/chunk_1/iprscan-20080501-17550292.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1119 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00063.11.ls Myosin head (motor domain) 1225.1 0 1 PF00063.11.fs Myosin head (motor domain) 1223.1 0 1 PF01843.9.ls DIL domain 192.9 7e-55 1 PF01843.9.fs DIL domain 192.3 1.1e-54 2 PF00612.17.ls IQ calmodulin-binding motif 154.9 2e-43 6 PF00612.17.fs IQ calmodulin-binding motif 142.9 1.1e-41 6 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00063.11.fs 1/1 76 754 .. 1 791 [] 1223.1 0 PF00063.11.ls 1/1 76 754 .. 1 791 [] 1225.1 0 PF00612.17.fs 1/6 770 790 .. 1 21 [] 19.6 9.1e-05 PF00612.17.ls 1/6 770 790 .. 1 21 [] 21.6 0.0026 PF00612.17.fs 2/6 793 813 .. 1 21 [] 21.3 2.9e-05 PF00612.17.ls 2/6 793 813 .. 1 21 [] 23.3 0.00081 PF00612.17.ls 3/6 818 838 .. 1 21 [] 23.0 0.001 PF00612.17.fs 3/6 818 838 .. 1 21 [] 21.0 3.6e-05 PF00612.17.fs 4/6 841 861 .. 1 21 [] 21.6 2.3e-05 PF00612.17.ls 4/6 841 861 .. 1 21 [] 23.6 0.00066 PF00612.17.fs 5/6 866 886 .. 1 21 [] 31.9 2e-08 PF00612.17.ls 5/6 866 886 .. 1 21 [] 33.9 5.3e-07 PF00612.17.ls 6/6 889 909 .. 1 21 [] 29.6 1e-05 PF00612.17.fs 6/6 889 909 .. 1 21 [] 27.6 3.7e-07 PF01843.9.fs 2/2 1686 1791 .. 1 113 [] 191.0 2.7e-54 PF01843.9.ls 1/1 1686 1791 .. 1 113 [] 192.9 7e-55 Alignments of top-scoring domains: PF00063.11.fs: domain 1 of 1, from 76 to 754: score 1223.1, E = 0 *->veDlveLtylnEpsvLhNLkkRYtsgdlIYTYsGlvLvsvNPYkrLp +Dl++L+yl+Ep+vLhNLk+R+ + IYTY+G+vLv++NPY++Lp KIAA1119 76 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP 122 iYteeiikaYrGkrrgElpPHiFAiAdeAYRsMlsdkeNQsIlisGESGA iY++++i aY+G+++g+++PHiFA+A+eAY++M +d +NQsI++sGESGA KIAA1119 123 IYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGA 172 GKTEntKkvmqYlAsvsgstpkvesaevtpnkeegsledqilqsNPiLEA GKT+++K+ m+Y+A v+gs++ e ++e+++l+s Pi+EA KIAA1119 173 GKTVSAKYAMRYFATVGGSAS------------ETNIEEKVLASSPIMEA 210 FGNAKTtRNNNSSRFGKfieIqFdatGsiNvTlvGgkIetYLLEKSRVvy GNAKTtRN+NSSRFGK+i+I Fd+ + i +G++++tYLLEKSRVv+ KIAA1119 211 IGNAKTTRNDNSSRFGKYIQIGFDKRYHI----IGANMRTYLLEKSRVVF 256 QtegERNFHIFYQLLagasaqeekkeLkLtspadpkdYaYLnqsgTynPc Q+ +ERN+HIFYQL+a a +e keL Lts ++d++Y++q+g KIAA1119 257 QADDERNYHIFYQLCAAAGLPE-FKELALTS---AEDFFYTSQGG----D 298 ytvDdgiDDaeeFkdtrkAlkiiGftdeeqrsifrilAAILhLGNieGFk ++ g+DDae F+ tr+A++++G +++ q+sif+i+A+ILhLG ++ + KIAA1119 299 TSI-EGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVA--I 345 qdqatTGneeqAGvtvsedteeileiiaeLLGvDaeeLekaLlsrriktG q +++ + + +s+++ l++++ LLGv + +e++L++r+++t KIAA1119 346 QAE----RDGDS-CSISPQDVY-LSNFCRLLGVEHSQMEHWLCHRKLVTT 389 gggkRretvtkpqnveqAryaRDALAKaiYsRLFdWiVekiNkaLsakeQ +et++k ++ +q+++aR+ALAK+iY LF WiVe+iNkaL++ + KIAA1119 390 -----SETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSL- 433 asdSrGGqaaegdDTVSITVVdlPraaldktasfIGvLDIyGFEIFaekN k++sfIGvLDIyGFE F e+N KIAA1119 434 -----------------------------KQHSFIGVLDIYGFETF-EVN 453 SFEQLcINYvNEKLQQfFNhhmFklEQEEYkrEgIeWtfIdyglDnqaci SFEQ+cINY+NEKLQQ+FN h+FklEQEEY++E+I+Wt Id+ +Dnq+ci KIAA1119 454 SFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDF-YDNQPCI 502 dLIEkKkPpGIlslLDEeCrfPkatDqtFldKLlqtfsskhprlthFAqk dLIE+K +GIl lLDEeC++Pk+tDq +++KL++++ s + hF qk KIAA1119 503 DLIEAK--LGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQ---HF-QK 545 pgrfkkgksrqgkteFiikHYAGdVeYnaegfleKNkDpLfddlisllks p r +++t+Fii+H+A +VeY +gfleKN+D+++++ i+ lk+ KIAA1119 546 P-R-------MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKA 587 SsdepllaeLFpeeelseAaNltlkapdfeadfdeeeaaaksaklgsgkg S+ pl+a+LF ++ + +++++ + ++++ + + ++ KIAA1119 588 SKF-PLVADLFHDD---------KDPVPATTPGKGSSSKISVRSARPPMK 627 ksgkkknfleTvgsqfkeslgeLmktLsstAnlnPHfvRCIKPNekKkag +s k+ ++ +Tvg+qf++sl+ Lm+tL++t +PH+vRCIKPN++K + KIAA1119 628 VSNKE-HK-KTVGHQFRTSLHLLMETLNAT---TPHYVRCIKPNDEKLPF 672 qFDaslVlhQlrclGvLEigiRirraGFPnRitfdeFlqRYrlLapktwp +FD++++ +Qlr++GvLE +iRi+ aG+P+R+++ +F++RYr+L +k KIAA1119 673 HFDPKRAVQQLRACGVLE-TIRISAAGYPSRWAYHDFFNRYRVLVKKREL 721 sgfrpewvgdakkgceliLqslrqtpgnlDkeeyrfGkTKiFfR<-* +++ d k c+++L+ l + D+++++fG TKiFfR KIAA1119 722 ANT------DKKAICRSVLENL-----IKDPDKFQFGRTKIFFR 754 PF00063.11.ls: domain 1 of 1, from 76 to 754: score 1225.1, E = 0 *->veDlveLtylnEpsvLhNLkkRYtsgdlIYTYsGlvLvsvNPYkrLp +Dl++L+yl+Ep+vLhNLk+R+ + IYTY+G+vLv++NPY++Lp KIAA1119 76 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP 122 iYteeiikaYrGkrrgElpPHiFAiAdeAYRsMlsdkeNQsIlisGESGA iY++++i aY+G+++g+++PHiFA+A+eAY++M +d +NQsI++sGESGA KIAA1119 123 IYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGA 172 GKTEntKkvmqYlAsvsgstpkvesaevtpnkeegsledqilqsNPiLEA GKT+++K+ m+Y+A v+gs++ e ++e+++l+s Pi+EA KIAA1119 173 GKTVSAKYAMRYFATVGGSAS------------ETNIEEKVLASSPIMEA 210 FGNAKTtRNNNSSRFGKfieIqFdatGsiNvTlvGgkIetYLLEKSRVvy GNAKTtRN+NSSRFGK+i+I Fd+ + i +G++++tYLLEKSRVv+ KIAA1119 211 IGNAKTTRNDNSSRFGKYIQIGFDKRYHI----IGANMRTYLLEKSRVVF 256 QtegERNFHIFYQLLagasaqeekkeLkLtspadpkdYaYLnqsgTynPc Q+ +ERN+HIFYQL+a a +e keL Lts ++d++Y++q+g KIAA1119 257 QADDERNYHIFYQLCAAAGLPE-FKELALTS---AEDFFYTSQGG----D 298 ytvDdgiDDaeeFkdtrkAlkiiGftdeeqrsifrilAAILhLGNieGFk ++ g+DDae F+ tr+A++++G +++ q+sif+i+A+ILhLG ++ + KIAA1119 299 TSI-EGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVA--I 345 qdqatTGneeqAGvtvsedteeileiiaeLLGvDaeeLekaLlsrriktG q +++ + + +s+++ l++++ LLGv + +e++L++r+++t KIAA1119 346 QAE----RDGDS-CSISPQDVY-LSNFCRLLGVEHSQMEHWLCHRKLVTT 389 gggkRretvtkpqnveqAryaRDALAKaiYsRLFdWiVekiNkaLsakeQ +et++k ++ +q+++aR+ALAK+iY LF WiVe+iNkaL++ + KIAA1119 390 -----SETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSL- 433 asdSrGGqaaegdDTVSITVVdlPraaldktasfIGvLDIyGFEIFaekN k++sfIGvLDIyGFE F e+N KIAA1119 434 -----------------------------KQHSFIGVLDIYGFETF-EVN 453 SFEQLcINYvNEKLQQfFNhhmFklEQEEYkrEgIeWtfIdyglDnqaci SFEQ+cINY+NEKLQQ+FN h+FklEQEEY++E+I+Wt Id+ +Dnq+ci KIAA1119 454 SFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDF-YDNQPCI 502 dLIEkKkPpGIlslLDEeCrfPkatDqtFldKLlqtfsskhprlthFAqk dLIE+K +GIl lLDEeC++Pk+tDq +++KL++++ s + hF qk KIAA1119 503 DLIEAK--LGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQ---HF-QK 545 pgrfkkgksrqgkteFiikHYAGdVeYnaegfleKNkDpLfddlisllks p r +++t+Fii+H+A +VeY +gfleKN+D+++++ i+ lk+ KIAA1119 546 P-R-------MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKA 587 SsdepllaeLFpeeelseAaNltlkapdfeadfdeeeaaaksaklgsgkg S+ pl+a+LF ++ + +++++ + ++++ + + ++ KIAA1119 588 SKF-PLVADLFHDD---------KDPVPATTPGKGSSSKISVRSARPPMK 627 ksgkkknfleTvgsqfkeslgeLmktLsstAnlnPHfvRCIKPNekKkag +s k+ ++ +Tvg+qf++sl+ Lm+tL++t +PH+vRCIKPN++K + KIAA1119 628 VSNKE-HK-KTVGHQFRTSLHLLMETLNAT---TPHYVRCIKPNDEKLPF 672 qFDaslVlhQlrclGvLEigiRirraGFPnRitfdeFlqRYrlLapktwp +FD++++ +Qlr++GvLE +iRi+ aG+P+R+++ +F++RYr+L +k KIAA1119 673 HFDPKRAVQQLRACGVLE-TIRISAAGYPSRWAYHDFFNRYRVLVKKREL 721 sgfrpewvgdakkgceliLqslrqtpgnlDkeeyrfGkTKiFfR<-* +++ d k c+++L+ l + D+++++fG TKiFfR KIAA1119 722 ANT------DKKAICRSVLENL-----IKDPDKFQFGRTKIFFR 754 PF00612.17.fs: domain 1 of 6, from 770 to 790: score 19.6, E = 9.1e-05 *->rraaikIQaawRGylaRkryk<-* r a i+IQ+ +RG+l++ +y+ KIAA1119 770 RTATIMIQKTVRGWLQKVKYH 790 PF00612.17.ls: domain 1 of 6, from 770 to 790: score 21.6, E = 0.0026 *->rraaikIQaawRGylaRkryk<-* r a i+IQ+ +RG+l++ +y+ KIAA1119 770 RTATIMIQKTVRGWLQKVKYH 790 PF00612.17.fs: domain 2 of 6, from 793 to 813: score 21.3, E = 2.9e-05 *->rraaikIQaawRGylaRkryk<-* + a +++Q+++RG+laR+ + KIAA1119 793 KGATLTLQRYCRGHLARRLAE 813 PF00612.17.ls: domain 2 of 6, from 793 to 813: score 23.3, E = 0.00081 *->rraaikIQaawRGylaRkryk<-* + a +++Q+++RG+laR+ + KIAA1119 793 KGATLTLQRYCRGHLARRLAE 813 PF00612.17.ls: domain 3 of 6, from 818 to 838: score 23.0, E = 0.001 *->rraaikIQaawRGylaRkryk<-* raa+++Q+++R+ +aR++y+ KIAA1119 818 IRAAVVLQKHYRMQRARQAYQ 838 PF00612.17.fs: domain 3 of 6, from 818 to 838: score 21.0, E = 3.6e-05 *->rraaikIQaawRGylaRkryk<-* raa+++Q+++R+ +aR++y+ KIAA1119 818 IRAAVVLQKHYRMQRARQAYQ 838 PF00612.17.fs: domain 4 of 6, from 841 to 861: score 21.6, E = 2.3e-05 *->rraaikIQaawRGylaRkryk<-* rraa++IQa+ R++ +R+ y+ KIAA1119 841 RRAAVVIQAFTRAMFVRRTYR 861 PF00612.17.ls: domain 4 of 6, from 841 to 861: score 23.6, E = 0.00066 *->rraaikIQaawRGylaRkryk<-* rraa++IQa+ R++ +R+ y+ KIAA1119 841 RRAAVVIQAFTRAMFVRRTYR 861 PF00612.17.fs: domain 5 of 6, from 866 to 886: score 31.9, E = 2e-08 *->rraaikIQaawRGylaRkryk<-* ++ a++IQ+++RG++aR++++ KIAA1119 866 EHKATTIQKHVRGWMARRHFQ 886 PF00612.17.ls: domain 5 of 6, from 866 to 886: score 33.9, E = 5.3e-07 *->rraaikIQaawRGylaRkryk<-* ++ a++IQ+++RG++aR++++ KIAA1119 866 EHKATTIQKHVRGWMARRHFQ 886 PF00612.17.ls: domain 6 of 6, from 889 to 909: score 29.6, E = 1e-05 *->rraaikIQaawRGylaRkryk<-* r+aai+IQ+a+R+ +aR+++k KIAA1119 889 RDAAIVIQCAFRMLKARRELK 909 PF00612.17.fs: domain 6 of 6, from 889 to 909: score 27.6, E = 3.7e-07 *->rraaikIQaawRGylaRkryk<-* r+aai+IQ+a+R+ +aR+++k KIAA1119 889 RDAAIVIQCAFRMLKARRELK 909 PF01843.9.fs: domain 2 of 2, from 1686 to 1791: score 191.0, E = 2.7e-54 *->qlfkQlFsfiNaqlfNsLllrrdaacCswsrGmqirynlsqLeeWcr q+fkQlF++iNa+++N+Lllr+d Csws+Gmq+ryn+sqLeeW+r KIAA1119 1686 QVFKQLFYMINAVTLNNLLLRKD--VCSWSTGMQLRYNISQLEEWLR 1730 eagledagdLawdeLeplrQavqLLqvkkktkedisldeiicdlCpaLnp +++l+++g a++++epl+Qa+qLLq kkkt ed+ e+ic+lC++L++ KIAA1119 1731 GRNLHQSG--AVQTMEPLIQAAQLLQLKKKTQEDA---EAICSLCTSLST 1775 aQlykiLtlYkpddye<-* +Q++kiL+lY+p +++ KIAA1119 1776 QQIVKILNLYTPLNEF 1791 PF01843.9.ls: domain 1 of 1, from 1686 to 1791: score 192.9, E = 7e-55 *->qlfkQlFsfiNaqlfNsLllrrdaacCswsrGmqirynlsqLeeWcr q+fkQlF++iNa+++N+Lllr+d Csws+Gmq+ryn+sqLeeW+r KIAA1119 1686 QVFKQLFYMINAVTLNNLLLRKD--VCSWSTGMQLRYNISQLEEWLR 1730 eagledagdLawdeLeplrQavqLLqvkkktkedisldeiicdlCpaLnp +++l+++g a++++epl+Qa+qLLq kkkt ed+ e+ic+lC++L++ KIAA1119 1731 GRNLHQSG--AVQTMEPLIQAAQLLQLKKKTQEDA---EAICSLCTSLST 1775 aQlykiLtlYkpddye<-* +Q++kiL+lY+p +++ KIAA1119 1776 QQIVKILNLYTPLNEF 1791 //