hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/smart.HMMs.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-18032082/chunk_1/iprscan-20080501-18032082.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1124 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SM00220 307.7 8e-88 1 SM00036 58.5 8.6e-13 1 SM00109 54.0 1.9e-11 1 SM00133 48.8 7.2e-10 1 SM00219 -27.4 1.9e-09 1 SM00285 42.4 6e-08 1 SM00233 35.1 9.4e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SM00219 1/1 125 391 .. 1 280 [] -27.4 1.9e-09 SM00220 1/1 125 391 .. 1 231 [] 307.7 8e-88 SM00133 1/1 392 454 .. 1 79 [] 48.8 7.2e-10 SM00109 1/1 1075 1124 .. 1 61 [] 54.0 1.9e-11 SM00233 1/1 1145 1265 .. 1 82 [] 35.1 9.4e-06 SM00036 1/1 1293 1568 .. 1 375 [] 58.5 8.6e-13 SM00285 1/1 1632 1667 .. 1 38 [] 42.4 6e-08 Alignments of top-scoring domains: SM00219: domain 1 of 1, from 125 to 391: score -27.4, E = 1.9e-09 *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda......keeFl + +k++G+GaFGeV ++k++++ A K L++ ++ + + F+ KIAA1124 125 FEIIKVIGRGAFGEVAVVKMKnteRIYAMKILNKWEmlkraeTACFR 171 rEakiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLld +E ++ + + + i +L+ + +e l++vm y gGdLl KIAA1124 172 EERDVLVNG--DCQWITALHYAFQDE-------NHLYLVMDYYVGGDLLT 212 yLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkv L k ++kl+ + + + +++ ++vHRD+ N+L++ n++ KIAA1124 213 LLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGH 262 vKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkd. ++ +DFG + + dd G ++ + g+ + +PE l+ KIAA1124 263 IRLADFGSCLKMNDD---GTVQSSVAV----GTPD-----YISPEILQAm 300 ....gkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkk +++ gk+ ++ D WS GV+++E++ +Ge+P + s e + ++++ KIAA1124 301 edgmGKYGPECDWWSLGVCMYEML-YGETPFYA-----ESLVETYGKIMN 344 GyRlpkPendl.piSsvtCPdelYdlMlqCWaedPedRPtFsel.....v + + + +++ + ++e dl+++ e R + +++ +++ KIAA1124 345 HEERFQFPSHVtD-----VSEEAKDLIQRLICS-RERRLGQNGIedfkkH 388 erl<-* ++ KIAA1124 389 AFF 391 SM00220: domain 1 of 1, from 125 to 391: score 307.7, E = 8e-88 *->YellkklGkGaFGkVylardkktgrlvAiKvik..........eril +e++k++G+GaFG+V ++ k+t r++A+K++++ + ++ ++ ++ KIAA1124 125 FEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNkwemlkraetACFR 171 rEikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgr E+++L ++d+ +I L+++f+d+++lylVm+y G GdL++ll k KIAA1124 172 EERDVLVNgDCQWITALHYAFQDeNHLYLVMDYYVG--GDLLTLLSKFED 219 rglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvK + l+E++arfy+ ++++a++ +H+++ +HRD+KP+N+LLd ++h+ KIAA1124 220 K-----LPEdMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVngHIR 264 laDFGlArql........ttfvGTpeYmAPEvl........gYgkpavDi laDFG++ +++++++ +++ vGTp+Y++PE+l+ +++ ++Yg+ ++D+ KIAA1124 265 LADFGSCLKMnddgtvqsSVAVGTPDYISPEILqamedgmgKYGP-ECDW 313 WSlGcilyElltGkpPFp..qldlifkkig...............Speak WSlG+++yE+l+G++PF+ + l +++ ki++++++ +++ ++ S+eak KIAA1124 314 WSLGVCMYEMLYGETPFYaeSLVETYGKIMnheerfqfpshvtdvSEEAK 363 dLikklLvkdPekRlta.eaLedeldikaHPff<-* dLi++l + e+Rl+ + + k+H ff KIAA1124 364 DLIQRLIC-SRERRLGQnGIED----FKKHAFF 391 SM00133: domain 1 of 1, from 392 to 454: score 48.8, E = 7.2e-10 *->rgiDWdkLenekkeiePPFkPkikeVyAsptDtsNFDkeFteetpv. g++W++++n +e+P++P+++ sp DtsNFD + + ++ KIAA1124 392 EGLNWENIRN----LEAPYIPDVS----SPSDTSNFDVDDDVLRNTe 430 .ltpvdsalsnsiqqeeaeteippdpFrGFsyvf<-* l p + + +++ + + F+GF++ KIAA1124 431 iLPPGSHTGFSGLHLP----------FIGFTFTT 454 SM00109: domain 1 of 1, from 1075 to 1124: score 54.0, E = 1.9e-11 *->Hkfvfrtf.kptfCdvCrksiwgsfkqaaksqglrCseCkvkcHkkC H+f++++f++pt C++C +++ g+ +q g+ C++C ++cH +C KIAA1124 1075 HQFSIKSFsSPTQCSHCTSLMVGLIRQ-----GYACEVCSFACHVSC 1116 aekvpaqshksglsC<-* ++ +p+ C KIAA1124 1117 KDGAPQ-------VC 1124 SM00233: domain 1 of 1, from 1145 to 1265: score 35.1, E = 9.4e-06 *->vikeGwLlkks....k.swkkryfvLfngvLlyyksk.........k + ++G++++ ++++ k++w++ y+v+++ L++y+ +++++++++ KIAA1124 1145 TAYKGHVKVPKptgvKkGWQRAYAVVCDCKLFLYDLPegkstqpgvI 1191 pkgsipLsgcsvre.p................cFeivt.dr.......tl + +++L++ +++++ ++ + +++ + F+++ + + ++++++l KIAA1124 1192 ASQVLDLRDDEFSVsSvlasdvihatrrdipcIFRVTAsLLgapsktsSL 1241 llqAeseeereeWvealqsaiaka<-* l+ +e+e e+++Wv l+ +++ + KIAA1124 1242 LILTENENEKKKWVGILEGLQSIL 1265 SM00036: domain 1 of 1, from 1293 to 1568: score 58.5, E = 8.6e-13 *->naakwnhpitcdqLWGkiLLvgTeeGLYvlnisrqlnkdhegtlekl ++a+++++ ++ vg eeGLYv+++ r + ++ KIAA1124 1293 LTAAIVDADRIA--------VGLEEGLYVIEVTR-------DVIVRA 1324 isrrsvtqiwvleennvLlmisGkkpqlyshpLsaltekkltqgntpiik + + v qi+++ +++++++ G++ ++ +p s+l KIAA1124 1325 ADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSL-------------- 1360 dalgsarlviRknvlttkipdvkGNchlcavkvngkrtgilflcaalqss + + ++i+ l p++kG c l a + kr ++l +a++ KIAA1124 1361 -DGAEGSFDIK---L----PETKG-CQLMAT-ATLKRNSGTCLFVAVKRL 1400 VvllaqwynplkkfklvksSNNiLNNEledikkflkklivplplfvelvs + + ++ + ++ ++ + p+++ + v KIAA1124 1401 ILCY-EIQRTKPFHRKFN------------------EIVAPGSVQCLAVL 1431 ssfelpkvciGsdkPVGGdaggdvvqfhqdphlNslkfkeslvskedlsl +++ +c+G + g++ +++ d lv+++d+sl KIAA1124 1432 RDR----LCVGYPS------GFCLLSIQGDGQP------LNLVNPNDPSL 1465 pfaseetssddaTCkpisvvqvqasdgGqRdelLlcydefgvfVNlqGle +f+s++++ +++++v ++ +e+Llc+ g++V++qG KIAA1124 1466 AFLSQQSF------DALCAVELES------EEYLLCFSHMGLYVDPQG-- 1501 vrrsrkpiltwefmpesfayvepyllafhsngieIrsiktgelNlqelad rr r+++l+w+ +p + +++ ++ + ++ g++++++ t e+ +q++ KIAA1124 1502 -RRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEW-VQTIG- 1548 rsiikarkiRlLgsCeisdrkIllsssp<-* +r+iR L s ll +p KIAA1124 1549 -----LRRIRPLNS---EGTLNLLNCEP 1568 SM00285: domain 1 of 1, from 1632 to 1667: score 42.4, E = 6e-08 *->IStPtGnFkHiaHVGPfDgatgeFtglptewesllkts<-* IS+Pt nF+H+aH+GP+Dg ++++++lp++ + KIAA1124 1632 ISNPT-NFNHVAHMGPGDG-MQVLMDLPLSAVPPSQEE 1667 //