# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hh15990.fasta.nr -Q ../query/KIAA1262.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1262, 1362 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7818321 sequences Expectation_n fit: rho(ln(x))= 6.0477+/-0.000195; mu= 10.6033+/- 0.011 mean_var=106.4540+/-20.803, 0's: 41 Z-trim: 84 B-trim: 507 in 2/64 Lambda= 0.124306 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 40, opt: 28, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|119568121|gb|EAW47736.1| spectrin repeat contai (5509) 8679 1568.9 0 gi|24417709|gb|AAN60442.1| nesprin-1 [Homo sapiens (8797) 8628 1559.9 0 gi|119568116|gb|EAW47731.1| spectrin repeat contai (8749) 8624 1559.2 0 gi|119568112|gb|EAW47727.1| spectrin repeat contai (8757) 8624 1559.2 0 gi|119568122|gb|EAW47737.1| spectrin repeat contai (8779) 8624 1559.2 0 gi|119568124|gb|EAW47739.1| spectrin repeat contai (8797) 8624 1559.2 0 gi|22597198|gb|AAN03486.1| enaptin [Homo sapiens] (8749) 8621 1558.7 0 gi|220675498|emb|CAX11912.1| spectrin repeat conta (8749) 8621 1558.7 0 gi|29839561|sp|Q8NF91.2|SYNE1_HUMAN RecName: Full= (8797) 8621 1558.7 0 gi|154277116|ref|NP_892006.2| spectrin repeat cont (8797) 8621 1558.7 0 gi|220675499|emb|CAX11913.1| spectrin repeat conta (8797) 8621 1558.7 0 gi|114609846|ref|XP_001139525.1| PREDICTED: nespri (8749) 8570 1549.5 0 gi|114609848|ref|XP_001138443.1| PREDICTED: nespri (8797) 8570 1549.5 0 gi|73946144|ref|XP_541154.2| PREDICTED: similar to (8760) 7949 1438.1 0 gi|149744149|ref|XP_001494325.1| PREDICTED: simila (8798) 7830 1416.8 0 gi|71480173|ref|NP_001025080.1| spectrin repeat co (8026) 7123 1290.0 0 gi|148671629|gb|EDL03576.1| mCG14633 [Mus musculus (1375) 7085 1282.5 0 gi|149038518|gb|EDL92848.1| rCG41130 [Rattus norve (1333) 7076 1280.9 0 gi|126311206|ref|XP_001381250.1| PREDICTED: simila (8794) 7023 1272.1 0 gi|118088392|ref|XP_419679.2| PREDICTED: similar t (8794) 6328 1147.4 0 gi|109072363|ref|XP_001100435.1| PREDICTED: simila (3347) 5849 1061.2 0 gi|189530625|ref|XP_001920330.1| PREDICTED: simila (8621) 4637 844.2 0 gi|47221249|emb|CAG13185.1| unnamed protein produc (6015) 3574 653.4 1.3e-183 gi|34849883|tpg|DAA01060.1| TPA: TPA_exp: spectrin (8407) 3455 632.2 4.4e-177 gi|32141360|gb|AAP74645.1| synaptic nuclear envelo (1594) 3352 613.1 4.6e-172 gi|189533134|ref|XP_698040.3| PREDICTED: similar t (8363) 3077 564.4 1.1e-156 gi|94734023|emb|CAH68877.2| novel protein similar (8130) 3075 564.0 1.4e-156 gi|47224613|emb|CAG03597.1| unnamed protein produc (8348) 2022 375.2 1e-99 gi|94732095|emb|CAI12049.2| novel protein similar (7319) 1974 366.5 3.6e-97 gi|198431763|ref|XP_002124429.1| PREDICTED: simila (8041) 1664 311.0 2.1e-80 gi|210122241|gb|EEA69949.1| hypothetical protein B (8539) 1457 273.9 3.3e-69 gi|194225084|ref|XP_001916097.1| PREDICTED: spectr (6871) 933 179.8 5.4e-41 gi|73963167|ref|XP_547851.2| PREDICTED: similar to (6880) 933 179.8 5.4e-41 gi|114653464|ref|XP_001169405.1| PREDICTED: spectr (6861) 881 170.5 3.5e-38 gi|114653460|ref|XP_001170042.1| PREDICTED: spectr (6885) 881 170.5 3.5e-38 gi|24417711|gb|AAN60443.1| nesprin-2 [Homo sapiens (6884) 876 169.6 6.4e-38 gi|116242809|sp|Q8WXH0.3|SYNE2_HUMAN RecName: Full (6885) 876 169.6 6.4e-38 gi|118918407|ref|NP_878918.2| spectrin repeat cont (6907) 876 169.6 6.5e-38 gi|119601249|gb|EAW80843.1| spectrin repeat contai (6884) 874 169.2 8.3e-38 gi|119601248|gb|EAW80842.1| spectrin repeat contai (6885) 874 169.2 8.3e-38 gi|17016967|gb|AAL33548.1|AF435011_1 NUANCE [Homo (6885) 873 169.1 9.4e-38 gi|119601250|gb|EAW80844.1| spectrin repeat contai (6825) 871 168.7 1.2e-37 gi|145699091|ref|NP_001005510.2| synaptic nuclear (6874) 826 160.6 3.2e-35 gi|210122242|gb|EEA69950.1| hypothetical protein B (8372) 806 157.1 4.5e-34 gi|109479539|ref|XP_001080795.1| PREDICTED: simila (6910) 788 153.8 3.6e-33 gi|109478368|ref|XP_216738.4| PREDICTED: similar t (3867) 783 152.7 4.4e-33 gi|115701088|ref|XP_001196159.1| PREDICTED: simila ( 966) 749 146.1 1.1e-31 gi|194034243|ref|XP_001925379.1| PREDICTED: spectr (6165) 735 144.3 2.4e-30 gi|57208507|emb|CAI42284.1| spectrin repeat contai (3321) 602 120.2 2.3e-23 gi|119568117|gb|EAW47732.1| spectrin repeat contai (3344) 602 120.2 2.3e-23 >>gi|119568121|gb|EAW47736.1| spectrin repeat containing (5509 aa) initn: 8679 init1: 8679 opt: 8679 Z-score: 8401.0 bits: 1568.9 E(): 0 Smith-Waterman score: 8679; 99.927% identity (100.000% similar) in 1362 aa overlap (1-1362:4148-5509) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4120 4130 4140 4150 4160 4170 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4180 4190 4200 4210 4220 4230 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4240 4250 4260 4270 4280 4290 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4300 4310 4320 4330 4340 4350 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4360 4370 4380 4390 4400 4410 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4420 4430 4440 4450 4460 4470 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4480 4490 4500 4510 4520 4530 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4540 4550 4560 4570 4580 4590 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4600 4610 4620 4630 4640 4650 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4660 4670 4680 4690 4700 4710 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4720 4730 4740 4750 4760 4770 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4780 4790 4800 4810 4820 4830 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4840 4850 4860 4870 4880 4890 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4900 4910 4920 4930 4940 4950 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4960 4970 4980 4990 5000 5010 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5020 5030 5040 5050 5060 5070 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5080 5090 5100 5110 5120 5130 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5140 5150 5160 5170 5180 5190 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5200 5210 5220 5230 5240 5250 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5260 5270 5280 5290 5300 5310 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5320 5330 5340 5350 5360 5370 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5380 5390 5400 5410 5420 5430 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5440 5450 5460 5470 5480 5490 1360 KIAA12 HQVTLGKIIFKK :::::::::::: gi|119 HQVTLGKIIFKK 5500 >>gi|24417709|gb|AAN60442.1| nesprin-1 [Homo sapiens] (8797 aa) initn: 8848 init1: 8628 opt: 8628 Z-score: 8348.9 bits: 1559.9 E(): 0 Smith-Waterman score: 8628; 99.852% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|244 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4190 4200 4210 4220 4230 4240 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4250 4260 4270 4280 4290 4300 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4310 4320 4330 4340 4350 4360 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4370 4380 4390 4400 4410 4420 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4430 4440 4450 4460 4470 4480 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4490 4500 4510 4520 4530 4540 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4550 4560 4570 4580 4590 4600 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4610 4620 4630 4640 4650 4660 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4670 4680 4690 4700 4710 4720 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4730 4740 4750 4760 4770 4780 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4790 4800 4810 4820 4830 4840 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4850 4860 4870 4880 4890 4900 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4910 4920 4930 4940 4950 4960 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA 4970 4980 4990 5000 5010 5020 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 5030 5040 5050 5060 5070 5080 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5090 5100 5110 5120 5130 5140 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5150 5160 5170 5180 5190 5200 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5210 5220 5230 5240 5250 5260 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5270 5280 5290 5300 5310 5320 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5330 5340 5350 5360 5370 5380 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5390 5400 5410 5420 5430 5440 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5450 5460 5470 5480 5490 5500 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|244 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5510 5520 5530 5540 5550 5560 1360 KIAA12 HQVTLGKIIFKK ::. : gi|244 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5570 5580 5590 5600 5610 5620 >>gi|119568116|gb|EAW47731.1| spectrin repeat containing (8749 aa) initn: 8762 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0 Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4120 4130 4140 4150 4160 4170 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4180 4190 4200 4210 4220 4230 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4240 4250 4260 4270 4280 4290 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4300 4310 4320 4330 4340 4350 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4360 4370 4380 4390 4400 4410 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4420 4430 4440 4450 4460 4470 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4480 4490 4500 4510 4520 4530 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4540 4550 4560 4570 4580 4590 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4600 4610 4620 4630 4640 4650 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4660 4670 4680 4690 4700 4710 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4720 4730 4740 4750 4760 4770 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4780 4790 4800 4810 4820 4830 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4840 4850 4860 4870 4880 4890 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4900 4910 4920 4930 4940 4950 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4960 4970 4980 4990 5000 5010 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5020 5030 5040 5050 5060 5070 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5080 5090 5100 5110 5120 5130 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5140 5150 5160 5170 5180 5190 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5200 5210 5220 5230 5240 5250 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5260 5270 5280 5290 5300 5310 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5320 5330 5340 5350 5360 5370 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5380 5390 5400 5410 5420 5430 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5440 5450 5460 5470 5480 5490 1360 KIAA12 HQVTLGKIIFKK ::. : gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5500 5510 5520 5530 5540 5550 >>gi|119568112|gb|EAW47727.1| spectrin repeat containing (8757 aa) initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0 Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4179-5533) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4150 4160 4170 4180 4190 4200 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4210 4220 4230 4240 4250 4260 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4270 4280 4290 4300 4310 4320 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4330 4340 4350 4360 4370 4380 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4390 4400 4410 4420 4430 4440 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4450 4460 4470 4480 4490 4500 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4510 4520 4530 4540 4550 4560 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4570 4580 4590 4600 4610 4620 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4630 4640 4650 4660 4670 4680 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4690 4700 4710 4720 4730 4740 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4750 4760 4770 4780 4790 4800 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4810 4820 4830 4840 4850 4860 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4870 4880 4890 4900 4910 4920 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4930 4940 4950 4960 4970 4980 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4990 5000 5010 5020 5030 5040 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5050 5060 5070 5080 5090 5100 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5110 5120 5130 5140 5150 5160 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5170 5180 5190 5200 5210 5220 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5230 5240 5250 5260 5270 5280 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5290 5300 5310 5320 5330 5340 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5350 5360 5370 5380 5390 5400 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5410 5420 5430 5440 5450 5460 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5470 5480 5490 5500 5510 5520 1360 KIAA12 HQVTLGKIIFKK ::. : gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5530 5540 5550 5560 5570 5580 >>gi|119568122|gb|EAW47737.1| spectrin repeat containing (8779 aa) initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0 Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4164-5518) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4140 4150 4160 4170 4180 4190 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4200 4210 4220 4230 4240 4250 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4260 4270 4280 4290 4300 4310 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4320 4330 4340 4350 4360 4370 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4380 4390 4400 4410 4420 4430 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4440 4450 4460 4470 4480 4490 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4500 4510 4520 4530 4540 4550 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4560 4570 4580 4590 4600 4610 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4620 4630 4640 4650 4660 4670 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4680 4690 4700 4710 4720 4730 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4740 4750 4760 4770 4780 4790 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4800 4810 4820 4830 4840 4850 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4860 4870 4880 4890 4900 4910 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4920 4930 4940 4950 4960 4970 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4980 4990 5000 5010 5020 5030 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5040 5050 5060 5070 5080 5090 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5100 5110 5120 5130 5140 5150 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5160 5170 5180 5190 5200 5210 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5220 5230 5240 5250 5260 5270 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5280 5290 5300 5310 5320 5330 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5340 5350 5360 5370 5380 5390 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5400 5410 5420 5430 5440 5450 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5460 5470 5480 5490 5500 5510 1360 KIAA12 HQVTLGKIIFKK ::. : gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5520 5530 5540 5550 5560 5570 >>gi|119568124|gb|EAW47739.1| spectrin repeat containing (8797 aa) initn: 8844 init1: 8624 opt: 8624 Z-score: 8345.0 bits: 1559.2 E(): 0 Smith-Waterman score: 8624; 99.779% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|119 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4190 4200 4210 4220 4230 4240 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4250 4260 4270 4280 4290 4300 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4310 4320 4330 4340 4350 4360 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4370 4380 4390 4400 4410 4420 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4430 4440 4450 4460 4470 4480 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4490 4500 4510 4520 4530 4540 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI 4550 4560 4570 4580 4590 4600 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4610 4620 4630 4640 4650 4660 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4670 4680 4690 4700 4710 4720 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4730 4740 4750 4760 4770 4780 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4790 4800 4810 4820 4830 4840 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4850 4860 4870 4880 4890 4900 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4910 4920 4930 4940 4950 4960 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|119 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4970 4980 4990 5000 5010 5020 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 5030 5040 5050 5060 5070 5080 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5090 5100 5110 5120 5130 5140 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5150 5160 5170 5180 5190 5200 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5210 5220 5230 5240 5250 5260 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5270 5280 5290 5300 5310 5320 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5330 5340 5350 5360 5370 5380 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5390 5400 5410 5420 5430 5440 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5450 5460 5470 5480 5490 5500 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5510 5520 5530 5540 5550 5560 1360 KIAA12 HQVTLGKIIFKK ::. : gi|119 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5570 5580 5590 5600 5610 5620 >>gi|22597198|gb|AAN03486.1| enaptin [Homo sapiens] (8749 aa) initn: 8759 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0 Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|225 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4120 4130 4140 4150 4160 4170 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4180 4190 4200 4210 4220 4230 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4240 4250 4260 4270 4280 4290 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4300 4310 4320 4330 4340 4350 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4360 4370 4380 4390 4400 4410 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4420 4430 4440 4450 4460 4470 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: gi|225 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI 4480 4490 4500 4510 4520 4530 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4540 4550 4560 4570 4580 4590 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4600 4610 4620 4630 4640 4650 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4660 4670 4680 4690 4700 4710 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4720 4730 4740 4750 4760 4770 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4780 4790 4800 4810 4820 4830 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4840 4850 4860 4870 4880 4890 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|225 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4900 4910 4920 4930 4940 4950 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4960 4970 4980 4990 5000 5010 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5020 5030 5040 5050 5060 5070 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5080 5090 5100 5110 5120 5130 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5140 5150 5160 5170 5180 5190 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5200 5210 5220 5230 5240 5250 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5260 5270 5280 5290 5300 5310 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5320 5330 5340 5350 5360 5370 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5380 5390 5400 5410 5420 5430 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|225 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5440 5450 5460 5470 5480 5490 1360 KIAA12 HQVTLGKIIFKK ::. : gi|225 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5500 5510 5520 5530 5540 5550 >>gi|220675498|emb|CAX11912.1| spectrin repeat containin (8749 aa) initn: 8759 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0 Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4148-5502) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|220 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4120 4130 4140 4150 4160 4170 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4180 4190 4200 4210 4220 4230 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4240 4250 4260 4270 4280 4290 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4300 4310 4320 4330 4340 4350 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4360 4370 4380 4390 4400 4410 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4420 4430 4440 4450 4460 4470 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: gi|220 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI 4480 4490 4500 4510 4520 4530 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4540 4550 4560 4570 4580 4590 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4600 4610 4620 4630 4640 4650 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4660 4670 4680 4690 4700 4710 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4720 4730 4740 4750 4760 4770 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4780 4790 4800 4810 4820 4830 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4840 4850 4860 4870 4880 4890 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|220 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4900 4910 4920 4930 4940 4950 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 4960 4970 4980 4990 5000 5010 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5020 5030 5040 5050 5060 5070 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5080 5090 5100 5110 5120 5130 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5140 5150 5160 5170 5180 5190 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5200 5210 5220 5230 5240 5250 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5260 5270 5280 5290 5300 5310 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5320 5330 5340 5350 5360 5370 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5380 5390 5400 5410 5420 5430 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5440 5450 5460 5470 5480 5490 1360 KIAA12 HQVTLGKIIFKK ::. : gi|220 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5500 5510 5520 5530 5540 5550 >>gi|29839561|sp|Q8NF91.2|SYNE1_HUMAN RecName: Full=Nesp (8797 aa) initn: 8841 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0 Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|298 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4190 4200 4210 4220 4230 4240 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4250 4260 4270 4280 4290 4300 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4310 4320 4330 4340 4350 4360 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4370 4380 4390 4400 4410 4420 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4430 4440 4450 4460 4470 4480 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4490 4500 4510 4520 4530 4540 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: gi|298 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI 4550 4560 4570 4580 4590 4600 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4610 4620 4630 4640 4650 4660 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4670 4680 4690 4700 4710 4720 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4730 4740 4750 4760 4770 4780 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4790 4800 4810 4820 4830 4840 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4850 4860 4870 4880 4890 4900 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4910 4920 4930 4940 4950 4960 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|298 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4970 4980 4990 5000 5010 5020 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 5030 5040 5050 5060 5070 5080 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5090 5100 5110 5120 5130 5140 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5150 5160 5170 5180 5190 5200 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5210 5220 5230 5240 5250 5260 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5270 5280 5290 5300 5310 5320 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5330 5340 5350 5360 5370 5380 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5390 5400 5410 5420 5430 5440 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5450 5460 5470 5480 5490 5500 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|298 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5510 5520 5530 5540 5550 5560 1360 KIAA12 HQVTLGKIIFKK ::. : gi|298 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5570 5580 5590 5600 5610 5620 >>gi|154277116|ref|NP_892006.2| spectrin repeat containi (8797 aa) initn: 8841 init1: 8621 opt: 8621 Z-score: 8342.1 bits: 1558.7 E(): 0 Smith-Waterman score: 8621; 99.705% identity (99.926% similar) in 1355 aa overlap (1-1355:4219-5573) 10 20 30 KIAA12 LDLCRQSNNLCLQREEDLQRTRDYHDCMNV :::::::::::::::::::::::::::::: gi|154 VNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNV 4190 4200 4210 4220 4230 4240 40 50 60 70 80 90 KIAA12 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 VEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNL 4250 4260 4270 4280 4290 4300 100 110 120 130 140 150 KIAA12 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 DDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIA 4310 4320 4330 4340 4350 4360 160 170 180 190 200 210 KIAA12 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 EALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALS 4370 4380 4390 4400 4410 4420 220 230 240 250 260 270 KIAA12 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 DAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDD 4430 4440 4450 4460 4470 4480 280 290 300 310 320 330 KIAA12 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 VSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQ 4490 4500 4510 4520 4530 4540 340 350 360 370 380 390 KIAA12 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQNI :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: gi|154 KCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNI 4550 4560 4570 4580 4590 4600 400 410 420 430 440 450 KIAA12 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 LEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQE 4610 4620 4630 4640 4650 4660 460 470 480 490 500 510 KIAA12 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 AILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGE 4670 4680 4690 4700 4710 4720 520 530 540 550 560 570 KIAA12 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 AVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQ 4730 4740 4750 4760 4770 4780 580 590 600 610 620 630 KIAA12 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 QLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDP 4790 4800 4810 4820 4830 4840 640 650 660 670 680 690 KIAA12 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 LAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELS 4850 4860 4870 4880 4890 4900 700 710 720 730 740 750 KIAA12 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 GPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLA 4910 4920 4930 4940 4950 4960 760 770 780 790 800 810 KIAA12 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESA ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: gi|154 ELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESA 4970 4980 4990 5000 5010 5020 820 830 840 850 860 870 KIAA12 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 EENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRD 5030 5040 5050 5060 5070 5080 880 890 900 910 920 930 KIAA12 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 SGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKAL 5090 5100 5110 5120 5130 5140 940 950 960 970 980 990 KIAA12 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 VSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILED 5150 5160 5170 5180 5190 5200 1000 1010 1020 1030 1040 1050 KIAA12 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 AVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSAL 5210 5220 5230 5240 5250 5260 1060 1070 1080 1090 1100 1110 KIAA12 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 GMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMV 5270 5280 5290 5300 5310 5320 1120 1130 1140 1150 1160 1170 KIAA12 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 ETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGL 5330 5340 5350 5360 5370 5380 1180 1190 1200 1210 1220 1230 KIAA12 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 YTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKL 5390 5400 5410 5420 5430 5440 1240 1250 1260 1270 1280 1290 KIAA12 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 KAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELH 5450 5460 5470 5480 5490 5500 1300 1310 1320 1330 1340 1350 KIAA12 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|154 QQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYIL 5510 5520 5530 5540 5550 5560 1360 KIAA12 HQVTLGKIIFKK ::. : gi|154 HQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQ 5570 5580 5590 5600 5610 5620 1362 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Wed Mar 4 06:35:36 2009 done: Wed Mar 4 06:39:53 2009 Total Scan time: 1936.920 Total Display time: 3.540 Function used was FASTA [version 34.26.5 April 26, 2007]