hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-23143370/chunk_1/iprscan-20080501-23143370.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1309 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF01344.15.ls Kelch motif 238.9 1e-68 6 PF01344.15.fs Kelch motif 228.3 1.5e-65 6 PF07707.5.ls BTB And C-terminal Kelch 125.3 1.6e-34 1 PF07707.5.fs BTB And C-terminal Kelch 123.3 6.1e-34 1 PF00651.21.ls BTB/POZ domain 112.8 9.1e-31 1 PF00651.21.fs BTB/POZ domain 111.0 1.8e-30 1 PF07646.5.ls Kelch motif 110.0 6.3e-30 6 PF07646.5.fs Kelch motif 104.2 3.6e-28 6 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00651.21.ls 1/1 66 175 .. 1 135 [] 112.8 9.1e-31 PF00651.21.fs 1/1 66 175 .. 1 135 [] 111.0 1.8e-30 PF07707.5.fs 1/1 180 281 .. 1 103 [] 123.3 6.1e-34 PF07707.5.ls 1/1 180 281 .. 1 103 [] 125.3 1.6e-34 PF01344.15.ls 1/6 313 360 .. 1 45 [] 8.5 0.39 PF01344.15.ls 2/6 362 412 .. 1 45 [] 58.7 1.8e-14 PF07646.5.fs 2/6 362 412 .. 1 54 [] 20.3 0.00012 PF01344.15.fs 2/6 362 412 .. 1 45 [] 56.7 2.8e-15 PF07646.5.ls 2/6 362 412 .. 1 54 [] 22.3 0.0016 PF01344.15.fs 3/6 414 459 .. 1 45 [] 54.6 1.1e-14 PF01344.15.ls 3/6 414 459 .. 1 45 [] 56.6 7.6e-14 PF01344.15.ls 4/6 461 506 .. 1 45 [] 44.1 4.5e-10 PF01344.15.fs 4/6 461 506 .. 1 45 [] 42.1 4e-11 PF07646.5.ls 4/6 461 506 .. 1 54 [] 32.8 1.1e-06 PF07646.5.fs 4/6 461 506 .. 1 54 [] 30.9 1.5e-07 PF01344.15.fs 5/6 508 558 .. 1 45 [] 33.2 1.3e-08 PF01344.15.ls 5/6 508 558 .. 1 45 [] 35.2 2.1e-07 PF07646.5.ls 5/6 508 558 .. 1 54 [] 15.0 0.26 PF01344.15.ls 6/6 560 607 .. 1 45 [] 35.8 1.4e-07 PF07646.5.fs 6/6 560 607 .. 1 54 [] 21.5 5.4e-05 PF07646.5.ls 6/6 560 607 .. 1 54 [] 23.4 0.00074 PF01344.15.fs 6/6 562 607 .. 3 45 .] 34.4 6e-09 Alignments of top-scoring domains: PF00651.21.ls: domain 1 of 1, from 66 to 175: score 112.8, E = 9.1e-31 *->lnelrkqgelcDVtLvvgdgsgrydvgkkfkAHKavLaacSpYFkal +++lr++g lcDVtL+ gd + f++H++ a++S+YFka+ KIAA1309 66 FDQLRLEGLLCDVTLMPGDT------DDAFPVHRVMMASASDYFKAM 106 FtgqfkesiteeessvsseieledvspedfealLefiYtgelsitqdqks Ftg+ ++e+ + i l +vs ++ +++fiYt++ls++ KIAA1309 107 FTGG-----MKEQDLMC--IKLHGVSKVGLRKIIDFIYTAKLSLN----- 144 PssckseenvedlLaaAadllqipslvdaCeefliksl<-* ++n++d L+aA ++lqi + d C fli KIAA1309 145 ------MDNLQDTLEAA-SFLQILPVLDFCKVFLISGV 175 PF00651.21.fs: domain 1 of 1, from 66 to 175: score 111.0, E = 1.8e-30 *->lnelrkqgelcDVtLvvgdgsgrydvgkkfkAHKavLaacSpYFkal +++lr++g lcDVtL+ gd + f++H++ a++S+YFka+ KIAA1309 66 FDQLRLEGLLCDVTLMPGDT------DDAFPVHRVMMASASDYFKAM 106 FtgqfkesiteeessvsseieledvspedfealLefiYtgelsitqdqks Ftg+ ++e+ + i l +vs ++ +++fiYt++ls++ KIAA1309 107 FTGG-----MKEQDLMC--IKLHGVSKVGLRKIIDFIYTAKLSLN----- 144 PssckseenvedlLaaAadllqipslvdaCeefliksl<-* ++n++d L+aA ++lqi + d C fli KIAA1309 145 ------MDNLQDTLEAA-SFLQILPVLDFCKVFLISGV 175 PF07707.5.fs: domain 1 of 1, from 180 to 281: score 123.3, E = 6.1e-34 *->CLgIrrfAdaygceeLaeaAdrfilqnFleVakseEFlqLskeqLie C+ + r+A +y+++e+ +++++f+l+nF++++++ EFl L++e+L + KIAA1309 180 CVEVGRIANTYNLTEVDKYVNSFVLKNFPALLSTGEFLKLPFERLAF 226 lLssDeLnVpsEeeVfeAvmrWvkhdvenRkkhlpeLLshVRLpLLspky +Lss++L ++E e+f+A +rW++ +++ R + +++L++++R+pL++p++ KIAA1309 227 VLSSNSLKHCTELELFKATCRWLRLEEP-RMDFAAKLMKNIRFPLMTPQE 275 Llevve<-* L ++v+ KIAA1309 276 LINYVQ 281 PF07707.5.ls: domain 1 of 1, from 180 to 281: score 125.3, E = 1.6e-34 *->CLgIrrfAdaygceeLaeaAdrfilqnFleVakseEFlqLskeqLie C+ + r+A +y+++e+ +++++f+l+nF++++++ EFl L++e+L + KIAA1309 180 CVEVGRIANTYNLTEVDKYVNSFVLKNFPALLSTGEFLKLPFERLAF 226 lLssDeLnVpsEeeVfeAvmrWvkhdvenRkkhlpeLLshVRLpLLspky +Lss++L ++E e+f+A +rW++ +++ R + +++L++++R+pL++p++ KIAA1309 227 VLSSNSLKHCTELELFKATCRWLRLEEP-RMDFAAKLMKNIRFPLMTPQE 275 Llevve<-* L ++v+ KIAA1309 276 LINYVQ 281 PF01344.15.ls: domain 1 of 6, from 313 to 360: score 8.5, E = 0.39 *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm + ++ + ++ GG+ ++ + ++ +YD + ++W+ l++m KIAA1309 313 QSDRTAIRSDTTHLVTLGGVLRqqlVVSKELRMYDEKAHEWKSLAPM 359 p<-* KIAA1309 360 D 360 PF01344.15.ls: domain 2 of 6, from 362 to 412: score 58.7, E = 1.8e-14 *->pRsgagvvvldgkiYviGGydg......qslnsvevYDpetntWtkl pR+ +g++v+++ +Yv+GG+++ ++++++++++v+++Dp+ n+W ++ KIAA1309 362 PRYQHGIAVIGNFLYVVGGQSNydtkgkTAVDTVFRFDPRYNKWMQV 408 psmp<-* +s++ KIAA1309 409 ASLN 412 PF07646.5.fs: domain 2 of 6, from 362 to 412: score 20.3, E = 0.00012 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW pry+h ++v+g+ lyvvGG + ++ g + +++ ++dp+ n+W KIAA1309 362 PRYQHGIAVIGNFLYVVGGQ---SNYDTKGKTAVDTVFRFDPRYNKW 405 eklpalp<-* +++l KIAA1309 406 MQVASLN 412 PF01344.15.fs: domain 2 of 6, from 362 to 412: score 56.7, E = 2.8e-15 *->pRsgagvvvldgkiYviGGydg......qslnsvevYDpetntWtkl pR+ +g++v+++ +Yv+GG+++ ++++++++++v+++Dp+ n+W ++ KIAA1309 362 PRYQHGIAVIGNFLYVVGGQSNydtkgkTAVDTVFRFDPRYNKWMQV 408 psmp<-* +s++ KIAA1309 409 ASLN 412 PF07646.5.ls: domain 2 of 6, from 362 to 412: score 22.3, E = 0.0016 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW pry+h ++v+g+ lyvvGG + ++ g + +++ ++dp+ n+W KIAA1309 362 PRYQHGIAVIGNFLYVVGGQ---SNYDTKGKTAVDTVFRFDPRYNKW 405 eklpalp<-* +++l KIAA1309 406 MQVASLN 412 PF01344.15.fs: domain 3 of 6, from 414 to 459: score 54.6, E = 1.1e-14 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< +R+++ +l+g++Y++GG++ l +ve+Y+p+tn+Wt+++ m+ KIAA1309 414 KRTFFHLSALKGYLYAVGGRNAaGELPTVECYNPRTNEWTYVAKMS 459 -* KIAA1309 - - PF01344.15.ls: domain 3 of 6, from 414 to 459: score 56.6, E = 7.6e-14 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< +R+++ +l+g++Y++GG++ l +ve+Y+p+tn+Wt+++ m+ KIAA1309 414 KRTFFHLSALKGYLYAVGGRNAaGELPTVECYNPRTNEWTYVAKMS 459 -* KIAA1309 - - PF01344.15.ls: domain 4 of 6, from 461 to 506: score 44.1, E = 4.5e-10 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< p +g++ +v++g++Y+ GG + +++ + ++Dp+t++W + ++m+ KIAA1309 461 PHYGHAGTVYGGVMYISGGITHdTFQKELMCFDPDTDKWIQKAPMT 506 -* KIAA1309 - - PF01344.15.fs: domain 4 of 6, from 461 to 506: score 42.1, E = 4e-11 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< p +g++ +v++g++Y+ GG + +++ + ++Dp+t++W + ++m+ KIAA1309 461 PHYGHAGTVYGGVMYISGGITHdTFQKELMCFDPDTDKWIQKAPMT 506 -* KIAA1309 - - PF07646.5.ls: domain 4 of 6, from 461 to 506: score 32.8, E = 1.1e-06 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW p+y+ha +v+gg +y++GG+ d ++ l+++dp+t +W KIAA1309 461 PHYGHAGTVYGGVMYISGGI--------THDTFQKELMCFDPDTDKW 499 eklpalp<-* +++ KIAA1309 500 IQKAPMT 506 PF07646.5.fs: domain 4 of 6, from 461 to 506: score 30.9, E = 1.5e-07 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW p+y+ha +v+gg +y++GG+ d ++ l+++dp+t +W KIAA1309 461 PHYGHAGTVYGGVMYISGGI--------THDTFQKELMCFDPDTDKW 499 eklpalp<-* +++ KIAA1309 500 IQKAPMT 506 PF01344.15.fs: domain 5 of 6, from 508 to 558: score 33.2, E = 1.3e-08 *->pRsgagvvvldgkiYviGGydg......qslnsvevYDpetntWtkl R +++++++ ++YviGG +++++ + s+e+Y+p ++Wt++ KIAA1309 508 VRGLHCMCTVGERLYVIGGNHFrgtsdyDDVLSCEYYSPILDQWTPI 554 psmp<-* + m KIAA1309 555 AAML 558 PF01344.15.ls: domain 5 of 6, from 508 to 558: score 35.2, E = 2.1e-07 *->pRsgagvvvldgkiYviGGydg......qslnsvevYDpetntWtkl R +++++++ ++YviGG +++++ + s+e+Y+p ++Wt++ KIAA1309 508 VRGLHCMCTVGERLYVIGGNHFrgtsdyDDVLSCEYYSPILDQWTPI 554 psmp<-* + m KIAA1309 555 AAML 558 PF07646.5.ls: domain 5 of 6, from 508 to 558: score 15.0, E = 0.26 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW r+ h ++++g++lyv+GG + rgt + d+++s ++ p +W KIAA1309 508 VRGLHCMCTVGERLYVIGGN--HFRGTSDYDDVLS-CEYYSPILDQW 551 eklpalp<-* ++++a+ KIAA1309 552 TPIAAML 558 PF01344.15.ls: domain 6 of 6, from 560 to 607: score 35.8, E = 1.4e-07 *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm s +gv+v+++kiYv+GGy+ +++ + v +YDp++++W+k+ ++ KIAA1309 560 GQSDVGVAVFENKIYVVGGYSWnnrCMVEIVQKYDPDKDEWHKVFDL 606 p<-* p KIAA1309 607 P 607 PF07646.5.fs: domain 6 of 6, from 560 to 607: score 21.5, E = 5.4e-05 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +++ + ++v ++k+yvvGG+ + n+ + ++ +dp++ +W KIAA1309 560 GQSDVGVAVFENKIYVVGGY------SWNNRCMVEIVQKYDPDKDEW 600 eklpalp<-* +k+ +lp KIAA1309 601 HKVFDLP 607 PF07646.5.ls: domain 6 of 6, from 560 to 607: score 23.4, E = 0.00074 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +++ + ++v ++k+yvvGG+ + n+ + ++ +dp++ +W KIAA1309 560 GQSDVGVAVFENKIYVVGGY------SWNNRCMVEIVQKYDPDKDEW 600 eklpalp<-* +k+ +lp KIAA1309 601 HKVFDLP 607 PF01344.15.fs: domain 6 of 6, from 562 to 607: score 34.4, E = 6e-09 *->sgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsmp< s +gv+v+++kiYv+GGy+ +++ + v +YDp++++W+k+ ++p KIAA1309 562 SDVGVAVFENKIYVVGGYSWnnrCMVEIVQKYDPDKDEWHKVFDLP 607 -* KIAA1309 - - //