hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/smart.HMMs.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-00030881/chunk_1/iprscan-20080502-00030881.nocrc
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Query sequence: KIAA1338
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SM00220                                                 185.9    3.8e-51   2
SM00219                                                 -40.3    1.2e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SM00220    1/2     132   385 ..     1   231 []    18.1  1.2e-10
SM00219    1/1     436   847 ..     1   280 []   -40.3  1.2e-08
SM00220    2/2     436   847 ..     1   231 []   167.8  1.1e-45

Alignments of top-scoring domains:
SM00220: domain 1 of 2, from 132 to 385: score 18.1, E = 1.2e-10
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..............
                          ++lGk     Vy a ++ tg  v    + +   + +++ ++  
    KIAA1338   132    IGSDEQLGK----LVYNALETATGGFV---LLYewvlqwqkkmgpfl 171  

                   ...............erilrEikiLkk.dHPNIVkLydvfed.....dkl
                   +++++++ ++ +++ + ++ E + L k  HPN+V+++ +   +++++  +
    KIAA1338   172 tsqekekidkckkqiQGTETEFNSLVKlSHPNVVRYLAMNLKeqddsIVV 221  

                   ylVmEyceGdlGdLfdllkkrgrrglrkvlsE.earfyfrQilsaLeYLH
                    +  E+++G   +L  +l + g+      ++ ++ r+y++Q+ls+L+YLH
    KIAA1338   222 DILVEHISG--VSLAAHLSHSGP------IPVhQLRRYTAQLLSGLDYLH 263  

                   sqgIiHRDLKPeNiLLds..hvKlaDFGlArql..........ttfvGTp
                   s+ ++H  L  +N+L+d +++vK++D  ++++l +  +++  + t v   
    KIAA1338   264 SNSVVHKVLSASNVLVDAegTVKITDYSISKRLadickedvfeQTRV--- 310  

                   eYmAPEvl.......gYgkpavDiWSlGcilyElltGkpPFpqldlifkk
                          ++++  + + gk + D+W lG +l  l  G+         + +
    KIAA1338   311 ------RFsdnalpyKTGK-KGDVWRLGLLLLSLSQGQE-----CGEYPV 348  

                   ig....SpeakdLikklLvkdPekRlta.eaLedeldikaHPff<-*
                     +++ + ++ d++kk+ + d ++R++ +++L+       H f+   
    KIAA1338   349 TIpsdlPADFQDFLKKCVCLDDKERWSPqQLLK-------HSFI    385  

SM00219: domain 1 of 1, from 436 to 847: score -40.3, E = 1.2e-08
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda....keeFlrE
                       + ++ LG GaFG V k + k ++   AVK +  +  +++ + +  E
    KIAA1338   436    FEELQLLGKGAFGAVIKVQNKldgCCYAVKRIPINPasrqFRRIKGE 482  

                   akiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyL
                     ++++l  +H+NiV+ + + +e                           
    KIAA1338   483 VTLLSRL--HHENIVRYYNAWIE--------------------------- 503  

                   rknrpk............................................
                   r  rp +++++++++++  ++++  ++++ +++++ ++ +   +++  ++
    KIAA1338   504 RHERPAgpgtpppdsgplakddraargqpasdtdgldsveaaapppilss 553  

                   ..................................................
                   + + +++++++ + + + ++++++++++++++++++  +++  + +++++
    KIAA1338   554 svewstsgersasarfpatgpgssddedddedehggvfsqsflpasdses 603  

                   ..................................................
                   +   +++++++++++++++ +++++ ++++++ +++  +    + +  ++
    KIAA1338   604 diifdnedensksqnqdedcnekngchesepsvtteavhylyiqmeycek 653  

                   ............lslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvg
                   ++ +++ +++    +  L      I +G +Y+++k+ +HRDL   N+ ++
    KIAA1338   654 stlrdtidqglyRDTVRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLD 703  

                   enkvvKIsDFGLsRdlyddDkkG.....eskdyYrkkggkggktllPir.
                   ++ +vKI+DFGL+ d+    ++ +++++  +d +++  +++  +++    
    KIAA1338   704 SDDHVKIGDFGLATDHLAF-SADskqddQTGDLIKSDPSGHLTGMVGTAl 752  

                   WmAPEsl..kdgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsnee
                     +PE+ ++ ++ ++ k D +S G+  +E+       Y  +    ++++e
    KIAA1338   753 YVSPEVQgsTKSAYNQKVDLFSLGIIFFEM------SYHPM----VTASE 792  

                   ...vleylkkGyRlpkPendlpiSs.vtCPdelYdlMlqCWaedPedRPt
                   +  vl++l++   ++ Pe+     ++ + +++  +++++  ++dP++RPt
    KIAA1338   793 rifVLNQLRDPTSPKFPED-----FdDGEHAKQKSVISWLLNHDPAKRPT 837  

                   Fsel..verl<-*
                    +el + e+l   
    KIAA1338   838 ATELlkSELL    847  

SM00220: domain 2 of 2, from 436 to 847: score 167.8, E = 1.1e-45
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..............
                      +e l++lGkGaFG V ++++k +g  +A+K+i+ ++ +++ ++ +++
    KIAA1338   436    FEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPinpasrqfrrikge 482  

                   ..................................................
                    +  ++ ++++  +  +   ++++++ +++++++++++  ++++  ++++
    KIAA1338   483 vtllsrlhhenivryynawierherpagpgtpppdsgplakddraargqp 532  

                   ..................................................
                    +++++ ++ +   +++  +++ + +++++++ + + + +++++++++++
    KIAA1338   533 asdtdgldsveaaapppilsssvewstsgersasarfpatgpgssddedd 582  

                   ........................erilrEikiLkk...dHPNIVkLydv
                   +++++++  +++  + ++++++   + + E +  +++++d+     ++++
    KIAA1338   583 dedehggvfsqsflpasdsesdiiFDNEDENSKSQNqdeDCNEKNGCHES 632  

                   fed......dklylVmEyceGdlGdLfdllkkrgrrglrkvlsE.earfy
                     + +++  ++ly+ mEyce    +L+d +++  +       +  + +++
    KIAA1338   633 EPSvtteavHYLYIQMEYCEK--STLRDTIDQGLY------RDTvRLWRL 674  

                   frQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaDFGlArql.....
                   fr+il++L+Y+H++g iHRDLKP Ni+Lds++hvK++DFGlA+     + 
    KIAA1338   675 FREILDGLAYIHEKGMIHRDLKPVNIFLDSddHVKIGDFGLATDHlafsa 724  

                   ....................ttfvGTpeYmAPEvl.....gYgkpavDiW
                   ++++++++++  +++++++ t +vGT  Y++PEv +++++ Y+  +vD  
    KIAA1338   725 dskqddqtgdliksdpsghlTGMVGTALYVSPEVQgstksAYNQ-KVDLF 773  

                   SlGcilyElltGkpPFp..qldlifkkig...............Speakd
                   SlG+i++E+ +  p    ++   ++++++++++++ +++ ++++    k+
    KIAA1338   774 SLGIIFFEMSY-HPMVTasERIFVLNQLRdptspkfpedfddgeHAKQKS 822  

                   LikklLvkdPekRlta.eaLedeldikaHPff<-*
                    i+ lL+ dP+kR+ta+e+L+        + +   
    KIAA1338   823 VISWLLNHDPAKRPTAtELLK-------SELL    847  

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