# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/hk08067mrp1.fasta.nr -Q ../query/KIAA1421.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1421, 1463 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7826796 sequences Expectation_n fit: rho(ln(x))= 5.4116+/-0.000187; mu= 13.7997+/- 0.010 mean_var=78.6838+/-15.273, 0's: 35 Z-trim: 43 B-trim: 0 in 0/67 Lambda= 0.144588 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 40, opt: 28, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|114657348|ref|XP_510458.2| PREDICTED: vacuolar (3836) 9213 1932.9 0 gi|119598006|gb|EAW77600.1| vacuolar protein sorti (2884) 9169 1923.6 0 gi|119598010|gb|EAW77604.1| vacuolar protein sorti (3033) 9169 1923.6 0 gi|119598009|gb|EAW77603.1| vacuolar protein sorti (3597) 9169 1923.7 0 gi|42454408|emb|CAF25188.1| VPS13C-2B protein [Hom (3628) 9169 1923.7 0 gi|119598011|gb|EAW77605.1| vacuolar protein sorti (3628) 9169 1923.7 0 gi|119598008|gb|EAW77602.1| vacuolar protein sorti (3722) 9169 1923.7 0 gi|74712594|sp|Q709C8.1|VP13C_HUMAN RecName: Full= (3753) 9169 1923.7 0 gi|119598013|gb|EAW77607.1| vacuolar protein sorti (3753) 9169 1923.7 0 gi|119902486|ref|XP_001251844.1| PREDICTED: vacuol (3753) 8440 1771.6 0 gi|74000341|ref|XP_851912.1| PREDICTED: similar to (3629) 8348 1752.4 0 gi|194206590|ref|XP_001918170.1| PREDICTED: simila (4053) 8262 1734.5 0 gi|42454406|emb|CAF25187.1| VPS13C-1B protein [Hom (3585) 8080 1696.5 0 gi|119598012|gb|EAW77606.1| vacuolar protein sorti (3585) 8080 1696.5 0 gi|119598005|gb|EAW77599.1| vacuolar protein sorti (3679) 8080 1696.5 0 gi|119598007|gb|EAW77601.1| vacuolar protein sorti (3710) 8080 1696.5 0 gi|42406425|emb|CAE75582.1| VPS13C-1A protein [Hom (3710) 8080 1696.5 0 gi|118574242|sp|Q8BX70.2|VP13C_MOUSE RecName: Full (3748) 8077 1695.9 0 gi|119902488|ref|XP_001251892.1| PREDICTED: vacuol (3710) 7366 1547.6 0 gi|74000345|ref|XP_864651.1| PREDICTED: similar to (3586) 7288 1531.3 0 gi|74000343|ref|XP_864640.1| PREDICTED: similar to (3599) 7288 1531.3 0 gi|149410857|ref|XP_001511058.1| PREDICTED: simila (3801) 7257 1524.8 0 gi|118095642|ref|XP_001233000.1| PREDICTED: vacuol (3758) 6495 1365.9 0 gi|148694211|gb|EDL26158.1| mCG127833 [Mus musculu (3217) 5532 1165.0 0 gi|149028882|gb|EDL84223.1| similar to vacuolar pr (2095) 5523 1162.9 0 gi|26339560|dbj|BAC33451.1| unnamed protein produc ( 771) 4492 947.6 0 gi|189521486|ref|XP_001922767.1| PREDICTED: simila (3699) 4195 886.1 0 gi|109483673|ref|XP_343419.3| PREDICTED: similar t (3574) 3377 715.5 1.7e-202 gi|219275534|ref|NP_001094445.2| vacuolar protein (3167) 3047 646.6 8.2e-182 gi|81888996|sp|Q5H8C4.1|VP13A_MOUSE RecName: Full= (3166) 3030 643.0 9.6e-181 gi|47214195|emb|CAG00823.1| unnamed protein produc (4005) 2326 496.3 1.9e-136 gi|52354635|gb|AAH82879.1| LOC445856 protein [Xeno ( 935) 2184 466.2 4.9e-128 gi|50415131|gb|AAH77364.1| LOC445856 protein [Xeno (1052) 2183 466.0 6.2e-128 gi|194224739|ref|XP_001916904.1| PREDICTED: vacuol (3126) 2179 465.5 2.6e-127 gi|119583002|gb|EAW62598.1| vacuolar protein sorti (2956) 2176 464.9 3.9e-127 gi|119583003|gb|EAW62599.1| vacuolar protein sorti (2986) 2176 464.9 3.9e-127 gi|119583001|gb|EAW62597.1| vacuolar protein sorti (2995) 2176 464.9 3.9e-127 gi|42454404|emb|CAF25186.1| chorein 1D [Homo sapie (3069) 2176 464.9 4e-127 gi|114625101|ref|XP_001147843.1| PREDICTED: vacuol (3069) 2176 464.9 4e-127 gi|114625099|ref|XP_520084.2| PREDICTED: vacuolar (3094) 2176 464.9 4e-127 gi|14289183|dbj|BAB59128.1| chorein [Homo sapiens] (3095) 2176 464.9 4e-127 gi|42406423|emb|CAE75581.1| chorein 2A [Homo sapie (3135) 2176 464.9 4e-127 gi|114625097|ref|XP_001148476.1| PREDICTED: vacuol (3135) 2176 464.9 4e-127 gi|14388939|gb|AAK61861.1|AF337532_1 chorea-acanth (3174) 2176 464.9 4.1e-127 gi|114625095|ref|XP_001148547.1| PREDICTED: vacuol (3174) 2176 464.9 4.1e-127 gi|71152975|sp|Q96RL7.2|VP13A_HUMAN RecName: Full= (3174) 2176 464.9 4.1e-127 gi|194033984|ref|XP_001925534.1| PREDICTED: vacuol ( 940) 2157 460.6 2.5e-126 gi|73946751|ref|XP_533522.2| PREDICTED: similar to (3194) 2162 462.0 3.1e-126 gi|169646798|ref|NP_001112365.1| vacuolar protein (3194) 2143 458.0 4.8e-125 gi|190340261|gb|AAI63680.1| Vps13a protein [Danio (3216) 2136 456.6 1.3e-124 >>gi|114657348|ref|XP_510458.2| PREDICTED: vacuolar prot (3836 aa) initn: 9000 init1: 9000 opt: 9213 Z-score: 10370.3 bits: 1932.9 E(): 0 Smith-Waterman score: 9213; 98.497% identity (99.522% similar) in 1464 aa overlap (1-1463:59-1522) 10 20 30 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESV :::: ::::::::::::: ::::::::::: gi|114 SYRPGDSAPAHRRGHARGAGVGRRRRGCHLQRWSPPSAAPGGSGSSLSWCLSATMVLESV 30 40 50 60 70 80 40 50 60 70 80 90 KIAA14 VADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLT 90 100 110 120 130 140 100 110 120 130 140 150 KIAA14 LKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAA :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: gi|114 LKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAEKEEKSLQDVKQKELSRIEEALQKAA 150 160 170 180 190 200 160 170 180 190 200 210 KIAA14 EKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 EKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKL 210 220 230 240 250 260 220 230 240 250 260 270 KIAA14 ATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKII 270 280 290 300 310 320 280 290 300 310 320 330 KIAA14 YKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 YKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLY 330 340 350 360 370 380 340 350 360 370 380 390 KIAA14 MNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 MNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPL 390 400 410 420 430 440 400 410 420 430 440 450 KIAA14 HTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQ :::::.::::::::::::::::::::::: :::::::::::::::::::::::::::::: gi|114 HTNGRQWWKYAIDSVLEVHIRRYTQMWSWINIKKHRQLLKSYKIAYKNKLTQSKVSEEIQ 450 460 470 480 490 500 460 470 480 490 500 510 KIAA14 KEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKK ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: gi|114 KEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGFWGKKESKKK 510 520 530 540 550 560 520 530 540 550 560 570 KIAA14 DEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTSVTIREN ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: gi|114 DEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTSVMIREN 570 580 590 600 610 620 580 590 600 610 620 630 KIAA14 KNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 KNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSS 630 640 650 660 670 680 640 650 660 670 680 690 KIAA14 LLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMK :::::::::::::::::::..::::::::::::::::::::::::::::::::::::::: gi|114 LLKIKFETNPEDSPADQTLLLQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMK 690 700 710 720 730 740 700 710 720 730 740 750 KIAA14 LEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQLNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQLNSK 750 760 770 780 790 800 760 770 780 790 800 810 KIAA14 DQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDI :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: gi|114 DQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEENWKKCRFQHPSTMHILQPMDI 810 820 830 840 850 860 820 830 840 850 860 870 KIAA14 HVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 HVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQ 870 880 890 900 910 920 880 890 900 910 920 930 KIAA14 VSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNE 930 940 950 960 970 980 940 950 960 970 980 990 KIAA14 ELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDY :::::::::::::::::::::::::::::::::::::::::.::::::.::::::::::: gi|114 ELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATVRTFDLTAVSYLKKISLDY 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 KIAA14 HEIEGSKKKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 HEIEGSKKKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLL 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 KIAA14 LQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRL ::::::::::::::::::::::::::::::::::::::::::::..:::::::::: ::: gi|114 LQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPRVIVSSRDSDIIGFRL 1110 1120 1130 1140 1150 1160 1120 1130 1140 1150 1160 1170 KIAA14 FAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKA :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 FAKLNAFCVVVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKA 1170 1180 1190 1200 1210 1220 1180 1190 1200 1210 1220 1230 KIAA14 VSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNN 1230 1240 1250 1260 1270 1280 1240 1250 1260 1270 1280 1290 KIAA14 FQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: gi|114 FQTAKESLSAATAQAAEKAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDL 1290 1300 1310 1320 1330 1340 1300 1310 1320 1330 1340 1350 KIAA14 GLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFL :::::::::::.::::::::::::::::::::::::::::::::.::::::::::::::: gi|114 GLIRVHNQFSLMSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIHHPDIQLLHPINLEFL 1350 1360 1370 1380 1390 1400 1360 1370 1380 1390 1400 1410 KIAA14 VNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQ ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: gi|114 VNRNLAASWYHKVPVVEIKGHLDSINVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQ 1410 1420 1430 1440 1450 1460 1420 1430 1440 1450 1460 KIAA14 ETGEIKEPLEISISQ-DVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLM ::::::::::::::: :::::::.:::::::::::::::::::::::::::::: gi|114 ETGEIKEPLEISISQQDVHDSKNSLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKTSEKK 1470 1480 1490 1500 1510 1520 gi|114 GRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPL 1530 1540 1550 1560 1570 1580 >>gi|119598006|gb|EAW77600.1| vacuolar protein sorting 1 (2884 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10322.5 bits: 1923.6 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119598010|gb|EAW77604.1| vacuolar protein sorting 1 (3033 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10322.2 bits: 1923.6 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119598009|gb|EAW77603.1| vacuolar protein sorting 1 (3597 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10321.1 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|42454408|emb|CAF25188.1| VPS13C-2B protein [Homo sa (3628 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10321.1 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|424 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|424 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|424 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|424 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119598011|gb|EAW77605.1| vacuolar protein sorting 1 (3628 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10321.1 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119598008|gb|EAW77602.1| vacuolar protein sorting 1 (3722 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10320.9 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|74712594|sp|Q709C8.1|VP13C_HUMAN RecName: Full=Vacu (3753 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10320.9 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|747 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|747 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|747 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119598013|gb|EAW77607.1| vacuolar protein sorting 1 (3753 aa) initn: 9169 init1: 9169 opt: 9169 Z-score: 10320.9 bits: 1923.7 E(): 0 Smith-Waterman score: 9169; 99.931% identity (100.000% similar) in 1439 aa overlap (25-1463:1-1439) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEE 1360 1370 1380 1390 1400 1410 1450 1460 KIAA14 IRSVDIINMLLNFEIKEVVVTLM ::::::::::::::::::::::: gi|119 IRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKK 1420 1430 1440 1450 1460 1470 >>gi|119902486|ref|XP_001251844.1| PREDICTED: vacuolar p (3753 aa) initn: 8254 init1: 8254 opt: 8440 Z-score: 9499.0 bits: 1771.6 E(): 0 Smith-Waterman score: 8440; 91.111% identity (97.500% similar) in 1440 aa overlap (25-1463:1-1440) 10 20 30 40 50 60 KIAA14 QRWSQPSAAPGGSGSSLSLCLSATMVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV :::::::::::::::::::::::::::::::::::: gi|119 MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNV 10 20 30 70 80 90 100 110 120 KIAA14 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 ALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASI 40 50 60 70 80 90 130 140 150 160 170 180 KIAA14 KYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKH :::: ::::::::.::.::::::::::::::::.:::::::::::::::::::::::::: gi|119 KYDAEKEEKSLQDIKQRELSRIEEALQKAAEKGAHSGEFIYGLENFVYKDIKPGRKRKKH 100 110 120 130 140 150 190 200 210 220 230 240 KIAA14 KKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPL ::::::::::::::::: ::::::::.::::::::::::::::::::::::::.:: ::: gi|119 KKHFKKPFKGLDRSKDKAKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDVSDPTRPL 160 170 180 190 200 210 250 260 270 280 290 300 KIAA14 SFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILD :::::::::::::::.::::::::::.::::::::::::::::::::::::: ::::::: gi|119 SFGVTLGELSLLTANKHWTPCILNEAEKIIYKLIRLDSLSAYWNVNCSMSYQGSREQILD 220 230 240 250 260 270 310 320 330 340 350 360 KIAA14 QLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKP :::.:::::.:::::.::::::::::::::::::::.:::::::: :::.:::::::::: gi|119 QLKSEILTSNNIPPNHQYIFQPISASAKLYMNPYAETELKTPKLDWNIEVQNIAIELTKP 280 290 300 310 320 330 370 380 390 400 410 420 KIAA14 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWS :::::::::::::::::::::::::::::::::::.::::::::::::::::::.::::: gi|119 QYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRQWWKYAIDSVLEVHIRRYTRMWSWS 340 350 360 370 380 390 430 440 450 460 470 480 KIAA14 NIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSG ::::::::::.:: ::::::::.:: :::::.:::::: ::::::::::::::::::::: gi|119 NIKKHRQLLKNYKSAYKNKLTQTKVPEEIQKQIQDLEKILDVFNIILARQQAQVEVIRSG 400 410 420 430 440 450 490 500 510 520 530 540 KIAA14 QKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE :::.:::.::.:::::::::.:.::::::::::::::::::::::::::::::::::::: gi|119 QKLKKKSTDTAEKRGGWFSGFWSKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSE 460 470 480 490 500 510 550 560 570 580 590 600 KIAA14 STHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVE :::::::::::::.:..:::::::.:::::.::::::::::::::::::::::::::::: gi|119 STHNLTLPKQYVAYIVALKLVSTSITIRENRNIPEILKIQIIGLGTQVSQRPGAQALKVE 520 530 540 550 560 570 610 620 630 640 650 660 KIAA14 AKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIY ::::::::::::::::.::::::::::.::::::.::::::.: :::::.:::::::::: gi|119 AKLEHWYITGLRQQDIIPSLVASIGDTASSLLKIEFETNPESSTADQTLVVQSQPVEVIY 580 590 600 610 620 630 670 680 690 700 710 720 KIAA14 DAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP ::::.::::::::::.:::::::::::::::::::::::::::::::::::::::::::: gi|119 DAKTINAVVEFFQSNRGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKP 640 650 660 670 680 690 730 740 750 760 770 780 KIAA14 SYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNV :::.:::::::::::::::::::::.:::::::::::.::::::::::::::::::::.: gi|119 SYLIVPQTGFHHEKSDLLILDFGTFRLNSKDQGLQKTSNSSLEEIMDKAYDKFDVEIKSV 700 710 720 730 740 750 790 800 810 820 830 840 KIAA14 QLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR :::::::.:.::.::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QLLFARADENWKECRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVR 760 770 780 790 800 810 850 860 870 880 890 900 KIAA14 ISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDD :::::::::: :.:::::::::::::::.::::::::: ::::::: :::: .:::::: gi|119 ISDQKMKDVLCLINSIPLPQKSSAQSPEKQVSSIPIISTRTKGLLGTPLLLDGIESESDD 820 830 840 850 860 870 910 920 930 940 950 960 KIAA14 EYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILV ::::::::. : :: :.:..::: :.:::::::::::::.::::::::::::::::::: gi|119 EYFDAEDGDIQPSKSTKASDVKKAPEAPNEELINLLLKFEVKEVILEFTKQQKEEDTILV 880 890 900 910 920 930 970 980 990 1000 1010 1020 KIAA14 FNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKKKPLHLISSSDKPGLDLLKVEYI ::::::::::::::::::.::::::::::::::.:::::::::::::::::::::::::: gi|119 FNVTQLGTEATMRTFDLTAVSYLKKISLDYHEIQGSKKKPLHLISSSDKPGLDLLKVEYI 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 KIAA14 KADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEV :::::::::::.: ::::: :::::::::::.::::..:::::::::::: :..: .:.. gi|119 KADKNGPSFQTTFEKTEQTFKVAFSSLNLLLHTQALLSSINYLTTIIPSDGQNMSDTKDI 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 KIAA14 QISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSL :.:::::::::.: :..:::.:::.: ::::::::::::.::.::::::::::::::::: gi|119 QVSTEKQQKNSALQKVVVSSKDSDMIHFRLFAKLNAFCVVVCDEKNNIAEIKIQGLDSSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 KIAA14 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSK :::::::::::::::::::::::::::::::::::::::.::::::::::::: :::::: gi|119 SLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFHFNLDLYPDATEGDSYTDMSK 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 KIAA14 VDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRS ::::.:::::::::::::::::::::::::::::::.::::::::::.:::::::.:::: gi|119 VDGVVSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKEALSAATAQAAEKAATSVKDFAQRS 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 KIAA14 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQL :::::::::::::::::::::::::::::::::::.::::::: :.: .::::::::::: gi|119 FRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVQNQFSLVSGENYSDPPVIDRMDVQL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 KIAA14 TKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLN :.: : :::::::: ::::::::::::::.::::::::::::::::::::::.::::.:: gi|119 TELKLSRTVIQPGISHPDIQLLHPINLEFFVNRNLAASWYHKVPVVEIKGHLESMNVNLN 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 KIAA14 QEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEIS-ISQDVHDSKNTLTTGVE :::::::::::.::: :. :::.:::::.::::::::::::: ..:::: :..: :.::: gi|119 QEDLNLLFRILAENLGEAPEDLNKVKPRIQETGEIKEPLEISTLKQDVHVSQDTSTAGVE 1360 1370 1380 1390 1400 1410 1440 1450 1460 KIAA14 EIRSVDIINMLLNFEIKEVVVTLM ::.:::::::::::::::::.::: gi|119 EIKSVDIINMLLNFEIKEVVITLMEKAEKKGRPLHELNVLQLGLEARVKAYDLTAEAYLK 1420 1430 1440 1450 1460 1470 1463 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Wed Mar 4 17:20:43 2009 done: Wed Mar 4 17:25:04 2009 Total Scan time: 1978.910 Total Display time: 2.350 Function used was FASTA [version 34.26.5 April 26, 2007]