hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-03141215/chunk_1/iprscan-20080502-03141215.nocrc
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Query sequence: KIAA1451
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N 
--------     -----------                                -----    ------- ---
PF01237.9.fs Oxysterol-binding protein                  211.5    1.8e-60   1
PF01237.9.ls Oxysterol-binding protein                  190.1      5e-54   1
PF00169.19.fs PH domain                                   58.6    2.2e-17   1
PF00169.19.ls PH domain                                   60.6    4.6e-15   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
PF00169.19.fs   1/1     199   315 ..     1    92 []    58.6  2.2e-17
PF00169.19.ls   1/1     199   315 ..     1    92 []    60.6  4.6e-15
PF01237.9.ls   1/1     425   835 ..     1   440 []   190.1    5e-54
PF01237.9.fs   1/1     463   783 ..    45   377 ..   211.5  1.8e-60

Alignments of top-scoring domains:
PF00169.19.fs: domain 1 of 1, from 199 to 315: score 58.6, E = 2.2e-17
                   *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.kkpkgsipLsg
                      +++  wL+ +g +ksw k ++vL+++vLl+yk  k+   +g++ L+ 
    KIAA1451   199    IVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKnGQWVGTVLLNA 245  

                   iqvtkvpdnkrkncFeirt.dr.......................etlll
                   +++ + p+ k+ +cF++ ++ +++    ++++++  ++ +++ ++  l++
    KIAA1451   246 CEIIERPSKKDGFCFKLFHpLEqsiwavkgpkgeavgsitqplpsSYLII 295  

                   qaeseeerkeWvkaiqsair<-*
                   +a+se + + W++a++ a++   
    KIAA1451   296 RATSESDGRCWMDALELALK    315  

PF00169.19.ls: domain 1 of 1, from 199 to 315: score 60.6, E = 4.6e-15
                   *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.kkpkgsipLsg
                      +++  wL+ +g +ksw k ++vL+++vLl+yk  k+   +g++ L+ 
    KIAA1451   199    IVMADWLKIRGTLKSWTKLWCVLKPGVLLIYKTQKnGQWVGTVLLNA 245  

                   iqvtkvpdnkrkncFeirt.dr.......................etlll
                   +++ + p+ k+ +cF++ ++ +++    ++++++  ++ +++ ++  l++
    KIAA1451   246 CEIIERPSKKDGFCFKLFHpLEqsiwavkgpkgeavgsitqplpsSYLII 295  

                   qaeseeerkeWvkaiqsair<-*
                   +a+se + + W++a++ a++   
    KIAA1451   296 RATSESDGRCWMDALELALK    315  

PF01237.9.ls: domain 1 of 1, from 425 to 835: score 190.1, E = 5e-54
                   *->kSqhsSsssltsklkfilsepkdltrRldipeeslspisLwsisqlw
                           +  + t++    l e +  +  +    e + +++ +   q +
    KIAA1451   425    -----KETTYTEQSHEELGEAGEASQ-TETVSEENKSLIWTLLKQVR 465  

                   vGkdLskitlPvfinEpkSmLqrvtedleYpelLdkAaaredsltrWfly
                   +G dLsk  lP+fi+Ep S L  +++    +++L++Aa +e++  r + +
    KIAA1451   466 PGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFR-LKK 514  

                   vaastlssysettrrvkKPlNPlLGEtFelkrendElp..nkgqyrllsE
                   v++++ls++  +++ +kKP NP+LGEtF   +    +p++n   +++++E
    KIAA1451   515 VVKWYLSGFYKKPKGLKKPYNPILGETFRCLWI---HPrtN-SKTFYIAE 560  

                   QVSHHPPvsAffaespkskwrvqgevqikskFlGkslavmkeGltvhtil
                   QVSHHPP+sAf+  + k    ++g +  kskF G+sl++  eG   ++ +
    KIAA1451   561 QVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE-ARLTF 609  

                   dikdingkpEtYtwtqPnttveGILvGkpfvElSGdesvinsstGdkcvI
                      +     E Y++t P  + +GIL G +  El G + ++  +tG+ + +
    KIAA1451   610 LNRG-----EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTGYSAIL 654  

                   eFktkGyf..SGkkdsfkgrivkdpdgnkdKEkklytlsGkWndsmyikK
                   eFk k + ++S  ++++ g+ +   ++      +l tl G+W+  ++++ 
    KIAA1451   655 EFKLKPFLgsSDCVNQISGKLK-LGKE------VLATLEGHWD--SEVFI 695  

                   vqsk.segelfl....DahktphealkvrpLeeqhelesrkaWkkvadal
                    ++k+  +e+f ++++D  +    +  v + eeq+++es k+W  v++a+
    KIAA1451   696 TDKKtDNSEVFWnptpDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAI 744  

                   kvgnltvftktkneleerqRpllkptesrgvedqralfkrledkedldke
                    + + t +t++k  lee qR+ ++ ++ +  e+  +lf+ l++     + 
    KIAA1451   745 NAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFE-LDPL----TG 789  

                   ekkekpeaddkerkqkgslyepkwfvpsgqpvtdKeklyikarkeyWefr
                   e+  k +++ +       l+    f++ g+  t  + +  +   +  + +
    KIAA1451   790 EWHYKFADTRP----WDPLNDMIQFEKDGVIQT--KVKHRTPMVSVPKMK 833  

                   Kk<-*
                    k   
    KIAA1451   834 HK    835  

PF01237.9.fs: domain 1 of 1, from 463 to 783: score 211.5, E = 1.8e-60
                   *->qlwvGkdLskitlPvfinEpkSmLqrvtedleYpelLdkAaaredsl
                      q ++G dLsk  lP+fi+Ep S L  +++    +++L++Aa +e++ 
    KIAA1451   463    QVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPY 509  

                   trWflyvaastlssysettrrvkKPlNPlLGEtFelkrendElp..nkgq
                    r + +v++++ls++  +++ +kKP NP+LGEtF   +    +p++n   
    KIAA1451   510 FR-LKKVVKWYLSGFYKKPKGLKKPYNPILGETFRCLWI---HPrtN-SK 554  

                   yrllsEQVSHHPPvsAffaespkskwrvqgevqikskFlGkslavmkeGl
                   +++++EQVSHHPP+sAf+  + k    ++g +  kskF G+sl++  eG 
    KIAA1451   555 TFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGE 604  

                   tvhtildikdingkpEtYtwtqPnttveGILvGkpfvElSGdesvinsst
                     ++ +   +     E Y++t P  + +GIL G +  El G + ++  +t
    KIAA1451   605 -ARLTFLNRG-----EDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKT 648  

                   GdkcvIeFktkGyf..SGkkdsfkgrivkdpdgnkdKEkklytlsGkWnd
                   G+ + +eFk k + ++S  ++++ g+ +   ++      +l tl G+W+ 
    KIAA1451   649 GYSAILEFKLKPFLgsSDCVNQISGKLK-LGKE------VLATLEGHWD- 690  

                   smyikKvqsk.segelfl....DahktphealkvrpLeeqhelesrkaWk
                    ++++  ++k+  +e+f ++++D  +    +  v + eeq+++es k+W 
    KIAA1451   691 -SEVFITDKKtDNSEVFWnptpDIKQWRLIRHTV-KFEEQGDFESEKLWQ 738  

                   kvadalkvgnltvftktkneleerqRpllkptesrgvedqralfk<-*
                    v++a+ + + t +t++k  lee qR+ ++ ++ +  e+  +lf+   
    KIAA1451   739 RVTRAINAKDQTEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFE    783  

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