hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-05015933/chunk_1/iprscan-20080502-05015933.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1514 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00041.11.ls Fibronectin type III domain 703.2 1.7e-208 12 PF00041.11.fs Fibronectin type III domain 693.0 2.1e-205 13 PF07679.6.fs Immunoglobulin I-set domain 127.1 1.8e-36 3 PF07679.6.ls Immunoglobulin I-set domain 113.2 7.1e-31 3 PF00047.15.ls Immunoglobulin domain 99.9 7.1e-27 3 PF00047.15.fs Immunoglobulin domain 96.2 9.2e-26 3 PF07686.7.fs Immunoglobulin V-set domain 38.1 2.8e-10 3 PF07686.7.ls Immunoglobulin V-set domain 27.2 5.3e-05 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00047.15.ls 1/3 1 59 [. 1 65 [] 30.3 6.2e-06 PF07679.6.ls 1/3 1 74 [. 1 96 [] 21.0 1.9e-05 PF07679.6.fs 1/3 3 74 .. 18 96 .] 38.8 1e-10 PF00047.15.fs 1/3 3 59 .. 4 65 .] 30.4 1.4e-07 PF07679.6.fs 2/3 79 169 .. 1 96 [] 67.1 5.8e-19 PF07679.6.ls 2/3 79 169 .. 1 96 [] 69.0 1.4e-17 PF00047.15.fs 2/3 93 154 .. 1 65 [] 35.3 6.1e-09 PF00047.15.ls 2/3 93 154 .. 1 65 [] 37.2 5.1e-08 PF07686.7.ls 2/2 172 264 .. 1 141 [] 18.8 0.00063 PF07679.6.fs 3/3 173 263 .. 1 96 [] 21.3 1.3e-05 PF07679.6.ls 3/3 173 263 .. 1 96 [] 23.2 1.3e-05 PF00047.15.fs 3/3 187 248 .. 1 65 [] 30.4 1.3e-07 PF00047.15.ls 3/3 187 248 .. 1 65 [] 32.3 1.5e-06 PF00041.11.fs 1/13 267 354 .. 1 84 [] 50.8 6e-14 PF00041.11.ls 1/12 267 354 .. 1 84 [] 52.8 1e-12 PF00041.11.ls 2/12 367 456 .. 1 84 [] 59.1 1.3e-14 PF00041.11.fs 2/13 367 456 .. 1 84 [] 57.1 9.1e-16 PF00041.11.fs 3/13 468 560 .. 1 84 [] 28.7 1.4e-07 PF00041.11.ls 3/12 468 560 .. 1 84 [] 30.7 4.9e-06 PF00041.11.fs 4/13 572 657 .. 1 84 [] 62.1 3.3e-17 PF00041.11.ls 4/12 572 657 .. 1 84 [] 64.1 4.1e-16 PF00041.11.fs 5/13 670 760 .. 1 84 [] 47.5 5.4e-13 PF00041.11.ls 5/12 670 760 .. 1 84 [] 49.5 1e-11 PF00041.11.ls 6/12 773 864 .. 1 84 [] 64.6 2.9e-16 PF00041.11.fs 6/13 773 864 .. 1 84 [] 62.6 2.4e-17 PF00041.11.fs 7/13 876 965 .. 1 84 [] 63.2 1.6e-17 PF00041.11.ls 7/12 876 965 .. 1 84 [] 65.2 1.9e-16 PF00041.11.ls 8/12 978 1064 .. 1 84 [] 57.7 3.5e-14 PF00041.11.fs 8/13 978 1064 .. 1 84 [] 55.7 2.3e-15 PF00041.11.ls 9/12 1080 1165 .. 1 84 [] 62.6 1.2e-15 PF00041.11.fs 9/13 1080 1165 .. 1 84 [] 60.6 9.4e-17 PF00041.11.ls 10/12 1178 1288 .. 1 84 [] 55.6 1.6e-13 PF00041.11.fs 10/13 1178 1288 .. 1 84 [] 53.5 9.8e-15 PF00041.11.ls 11/12 1300 1389 .. 1 84 [] 80.6 4.4e-21 PF00041.11.fs 11/13 1300 1389 .. 1 84 [] 78.6 6.2e-22 PF00041.11.ls 12/12 1401 1489 .. 1 84 [] 60.6 4.8e-15 PF00041.11.fs 12/13 1401 1489 .. 1 84 [] 58.5 3.6e-16 Alignments of top-scoring domains: PF00047.15.ls: domain 1 of 3, from 1 to 59: score 30.3, E = 6.2e-06 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq + v ++C+++ g p++++tW+++ ++ + l+++ ++n+++ KIAA1514 1 -KVVDIPCQAK--GVPPPSITWYKDAAvVEvEKLTRFRQRNDGG--- 41 tsLtitnvtpeDggtYtCvv<-* L+i+ + p+D+g + C + KIAA1514 42 --LQISGLVPDDTGMFQCFA 59 PF07679.6.ls: domain 1 of 3, from 1 to 74: score 21.0, E = 1.9e-05 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvl.l + ++ C+++G P+P+++W+Kd + + +l KIAA1514 1 ---------------KVVDIPCQAKGVPPPSITWYKDAAVVEV-EkL 31 psdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV rf+ ++dg L Is+ pdD G C A+N aGe+++s L V KIAA1514 32 T--RFRQRNDG-----GLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 74 <-* KIAA1514 - - PF07679.6.fs: domain 1 of 3, from 3 to 74: score 38.8, E = 1e-10 *->arfeCkVtGtPePtVsWfKdGqplssvl.lpsdrfkvtydgGsgtyt ++ C+++G P+P+++W+Kd + + +l rf+ ++dg KIAA1514 3 VDIPCQAKGVPPPSITWYKDAAVVEV-EkLT--RFRQRNDG-----G 41 LtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV<-* L Is+ pdD G C A+N aGe+++s L V KIAA1514 42 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAV 74 PF00047.15.fs: domain 1 of 3, from 3 to 59: score 30.4, E = 1.4e-07 *->vtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyqtsL v ++C+++ g p++++tW+++ ++ + l+++ ++n+++ L KIAA1514 3 VDIPCQAK--GVPPPSITWYKDAAvVEvEKLTRFRQRNDGG-----L 42 titnvtpeDggtYtCvv<-* +i+ + p+D+g + C + KIAA1514 43 QISGLVPDDTGMFQCFA 59 PF07679.6.fs: domain 2 of 3, from 79 to 169: score 67.1, E = 5.8e-19 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssv.l. P +t+ p d +V G s+++ C+ +G P P ++W K+ + l s + + KIAA1514 79 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGsVq 125 lpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLt lp rf ++g +L Is ++D+G+YtC AtNs G +easa L KIAA1514 126 LP--RFTPLESG-----SLLISPTHISDAGTYTCLATNSRGVDEASADLV 168 V<-* V KIAA1514 169 V 169 PF07679.6.ls: domain 2 of 3, from 79 to 169: score 69.0, E = 1.4e-17 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssv.l. P +t+ p d +V G s+++ C+ +G P P ++W K+ + l s + + KIAA1514 79 PNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGsVq 125 lpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLt lp rf ++g +L Is ++D+G+YtC AtNs G +easa L KIAA1514 126 LP--RFTPLESG-----SLLISPTHISDAGTYTCLATNSRGVDEASADLV 168 V<-* V KIAA1514 169 V 169 PF00047.15.fs: domain 2 of 3, from 93 to 154: score 35.3, E = 6.1e-09 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvt.ssenngdsty G sv L C++ +g p + +tW+++ l +g ++ + +++ +++ KIAA1514 93 GMSVVLACET--SGAPRPAITWQKGERiLAsGSVQLpRFTPLESGS- 136 qtsLtitnvtpeDggtYtCvv<-* L i+++ +D+gtYtC + KIAA1514 137 ---LLISPTHISDAGTYTCLA 154 PF00047.15.ls: domain 2 of 3, from 93 to 154: score 37.2, E = 5.1e-08 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvt.ssenngdsty G sv L C++ +g p + +tW+++ l +g ++ + +++ +++ KIAA1514 93 GMSVVLACET--SGAPRPAITWQKGERiLAsGSVQLpRFTPLESGS- 136 qtsLtitnvtpeDggtYtCvv<-* L i+++ +D+gtYtC + KIAA1514 137 ---LLISPTHISDAGTYTCLA 154 PF07686.7.ls: domain 2 of 2, from 172 to 264: score 18.8, E = 0.00063 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss +t pp +v G+ +++ C ++ KIAA1514 172 RTRITK-PPQ------------DQSVIKGTQASMVCGVT-------- 197 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls ++p ++ ++y ++++ t g + r++l KIAA1514 198 ------------HDP---------RVTIRYIWEKDGATLGTESHPRIRLD 226 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* +n+s L+Is+ + D GtY+C v++ +++ +L V+ KIAA1514 227 RNGS-----LHISQTWSGDIGTYTCRVISA-GGNDSRSAHLRVR 264 PF07679.6.fs: domain 3 of 3, from 173 to 263: score 21.3, E = 1.3e-05 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVs..WfKdGqplssvl ++t++p+d+ V G a++ C Vt +P t+ W KdG l KIAA1514 173 TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRyiWEKDGATLGT-- 217 lpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLt +++ +++ d + +L Is+ ++D G+YtC++ +G ++ sa+L KIAA1514 218 --ESHPRIRLDR---NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLR 262 V<-* V KIAA1514 263 V 263 PF07679.6.ls: domain 3 of 3, from 173 to 263: score 23.2, E = 1.3e-05 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVs..WfKdGqplssvl ++t++p+d+ V G a++ C Vt +P t+ W KdG l KIAA1514 173 TRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRyiWEKDGATLGT-- 217 lpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLt +++ +++ d + +L Is+ ++D G+YtC++ +G ++ sa+L KIAA1514 218 --ESHPRIRLDR---NGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLR 262 V<-* V KIAA1514 263 V 263 PF00047.15.fs: domain 3 of 3, from 187 to 248: score 30.4, E = 1.3e-07 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq G ++++C v++ + +++ W ++g +l+++ + ++ ++++s KIAA1514 187 GTQASMVCGVTHDPRVTIRYIWEKDGAtLGtESHPRIRLDRNGS--- 230 tsLtitnvtpeDggtYtCvv<-* L+i+++ ++D gtYtC+v KIAA1514 231 --LHISQTWSGDIGTYTCRV 248 PF00047.15.ls: domain 3 of 3, from 187 to 248: score 32.3, E = 1.5e-06 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq G ++++C v++ + +++ W ++g +l+++ + ++ ++++s KIAA1514 187 GTQASMVCGVTHDPRVTIRYIWEKDGAtLGtESHPRIRLDRNGS--- 230 tsLtitnvtpeDggtYtCvv<-* L+i+++ ++D gtYtC+v KIAA1514 231 --LHISQTWSGDIGTYTCRV 248 PF00041.11.fs: domain 1 of 13, from 267 to 354: score 50.8, E = 6e-14 *->PsaPtnltvtdv..tstsltlsWspPt.gngpitgYevtyRqpkngg P aP+ + +t + + l+W++P++gn+p+ +Y ++ ++ n + KIAA1514 267 PHAPEHPVATLStvERRAINLTWTKPFdGNSPLIRYILEM-SENNAP 312 e.wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +++ +v++ +ts+t++gL+P + Y++r+ Avn++G+G++S KIAA1514 313 WtVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGkGQFS 354 PF00041.11.ls: domain 1 of 12, from 267 to 354: score 52.8, E = 1e-12 *->PsaPtnltvtdv..tstsltlsWspPt.gngpitgYevtyRqpkngg P aP+ + +t + + l+W++P++gn+p+ +Y ++ ++ n + KIAA1514 267 PHAPEHPVATLStvERRAINLTWTKPFdGNSPLIRYILEM-SENNAP 312 e.wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +++ +v++ +ts+t++gL+P + Y++r+ Avn++G+G++S KIAA1514 313 WtVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGkGQFS 354 PF00041.11.ls: domain 2 of 12, from 367 to 456: score 59.1, E = 1.3e-14 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ +P+n+ ++++t+ s+ ++W+pP++++ ng + gY ++y + ++ KIAA1514 367 PtAPPQNVIASGRTNQSIMIQWQPPPeshQNGILKGYIIRY-CLAGL 412 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + + + +++ + + l++L t+Y++ V+A+n +G G +S KIAA1514 413 PVgyQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGlGVYS 456 PF00041.11.fs: domain 2 of 13, from 367 to 456: score 57.1, E = 9.1e-16 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ +P+n+ ++++t+ s+ ++W+pP++++ ng + gY ++y + ++ KIAA1514 367 PtAPPQNVIASGRTNQSIMIQWQPPPeshQNGILKGYIIRY-CLAGL 412 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + + + +++ + + l++L t+Y++ V+A+n +G G +S KIAA1514 413 PVgyQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGlGVYS 456 PF00041.11.fs: domain 3 of 13, from 468 to 560: score 28.7, E = 1.4e-07 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ +P+n+++++++st+++++W++P+++ ng +gY++ ++ KIAA1514 468 PtVPPGNVHAEATNSTTIRFTWNAPSpqfINGINQGYKLIA-WEPEQ 513 gewkeltvpgt.....ttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +e+++ + +++ +++ + ++gLk teY +V ++ G+Gp+S KIAA1514 514 EEEVTMVTARPnfqdsIHVGFVSGLKKFTEYFTSVLCFTTPGdGPRS 560 PF00041.11.ls: domain 3 of 12, from 468 to 560: score 30.7, E = 4.9e-06 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ +P+n+++++++st+++++W++P+++ ng +gY++ ++ KIAA1514 468 PtVPPGNVHAEATNSTTIRFTWNAPSpqfINGINQGYKLIA-WEPEQ 513 gewkeltvpgt.....ttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +e+++ + +++ +++ + ++gLk teY +V ++ G+Gp+S KIAA1514 514 EEEVTMVTARPnfqdsIHVGFVSGLKKFTEYFTSVLCFTTPGdGPRS 560 PF00041.11.fs: domain 4 of 13, from 572 to 657: score 62.1, E = 3.3e-17 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpknggew P++++ l+++++ +tsl +sW+ P + ng +tgY++ + ++ n + KIAA1514 572 PGPVGHLSFSEILDTSLKVSWQEPGeKNGILTGYRISW-EEYNRTNT 617 kelt.vpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + +p++t +y +tgL++ t+Yt+ V+A + +G+G+ S KIAA1514 618 RVTHyLPNVTLEYRVTGLTALTTYTIEVAAMTSKGqGQVS 657 PF00041.11.ls: domain 4 of 12, from 572 to 657: score 64.1, E = 4.1e-16 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpknggew P++++ l+++++ +tsl +sW+ P + ng +tgY++ + ++ n + KIAA1514 572 PGPVGHLSFSEILDTSLKVSWQEPGeKNGILTGYRISW-EEYNRTNT 617 kelt.vpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + +p++t +y +tgL++ t+Yt+ V+A + +G+G+ S KIAA1514 618 RVTHyLPNVTLEYRVTGLTALTTYTIEVAAMTSKGqGQVS 657 PF00041.11.fs: domain 5 of 13, from 670 to 760: score 47.5, E = 5.4e-13 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpkngge. P++Ptnl ++++++ s+tl+ p +g i++ v+ q ge+ KIAA1514 670 PGPPTNLGISNIGPRSVTLQFRPGYdGKTSISRWLVEA-QVGVVGEg 715 .....wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ ++l+ ++++s+++ +L+P t Y++r + vn +G++p+S KIAA1514 716 eewllIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGtSPPS 760 PF00041.11.ls: domain 5 of 12, from 670 to 760: score 49.5, E = 1e-11 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpkngge. P++Ptnl ++++++ s+tl+ p +g i++ v+ q ge+ KIAA1514 670 PGPPTNLGISNIGPRSVTLQFRPGYdGKTSISRWLVEA-QVGVVGEg 715 .....wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ ++l+ ++++s+++ +L+P t Y++r + vn +G++p+S KIAA1514 716 eewllIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGtSPPS 760 PF00041.11.ls: domain 6 of 12, from 773 to 864: score 64.6, E = 2.9e-16 *->P.saPtnltvtdvtstsltlsWspPt.....gngpitgYevtyRqpk P+ aP n++ + ++tsl l+W p ++ + +gn + gY+++y + + KIAA1514 773 PdMAPANVSLRTASETSLWLRWMPLPemeynGNPESVGYKIKY-SRS 818 ngge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +g +++ ++ +++++ yt+++L++ teY v+VqA n++G+Gp+S KIAA1514 819 DGHGktLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGsGPWS 864 PF00041.11.fs: domain 6 of 13, from 773 to 864: score 62.6, E = 2.4e-17 *->P.saPtnltvtdvtstsltlsWspPt.....gngpitgYevtyRqpk P+ aP n++ + ++tsl l+W p ++ + +gn + gY+++y + + KIAA1514 773 PdMAPANVSLRTASETSLWLRWMPLPemeynGNPESVGYKIKY-SRS 818 ngge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +g +++ ++ +++++ yt+++L++ teY v+VqA n++G+Gp+S KIAA1514 819 DGHGktLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGsGPWS 864 PF00041.11.fs: domain 7 of 13, from 876 to 965: score 63.2, E = 1.6e-17 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+s Ptn+++ ++ts+s+ ++Ws ++ ++ng + gY+v y ++k++ KIAA1514 876 PsSGPTNVSALATTSSSMLVRWSEVPeadRNGLVLGYKVMY-KEKDS 921 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ ++l ++++s++ltgL ++ Y+v+V A +++G+G +S KIAA1514 922 DTqpRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGdGSPS 965 PF00041.11.ls: domain 7 of 12, from 876 to 965: score 65.2, E = 1.9e-16 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+s Ptn+++ ++ts+s+ ++Ws ++ ++ng + gY+v y ++k++ KIAA1514 876 PsSGPTNVSALATTSSSMLVRWSEVPeadRNGLVLGYKVMY-KEKDS 921 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ ++l ++++s++ltgL ++ Y+v+V A +++G+G +S KIAA1514 922 DTqpRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGdGSPS 965 PF00041.11.ls: domain 8 of 12, from 978 to 1064: score 57.7, E = 3.5e-14 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyR.qpkngge P++P ++ + +v++ts++l W+pP +ng i Y++t R ++ + KIAA1514 978 PGPPMGILFPEVRTTSVRLIWQPPAaPNGIILAYQITHRlNTTTANT 1024 wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + + +++++yt tgLkP + Y +r++A++++G G+ KIAA1514 1025 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGwGEAA 1064 PF00041.11.fs: domain 8 of 13, from 978 to 1064: score 55.7, E = 2.3e-15 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyR.qpkngge P++P ++ + +v++ts++l W+pP +ng i Y++t R ++ + KIAA1514 978 PGPPMGILFPEVRTTSVRLIWQPPAaPNGIILAYQITHRlNTTTANT 1024 wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + + +++++yt tgLkP + Y +r++A++++G G+ KIAA1514 1025 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGwGEAA 1064 PF00041.11.ls: domain 9 of 12, from 1080 to 1165: score 62.6, E = 1.2e-15 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpkngge. Ps P ++ +dv++ s+ lsW+p ++g +p+ +Y+++ R + +g KIAA1514 1080 PSRPM-VQQEDVRARSVLLSWEPGSdGLSPVRYYTIQTR-ELPSGRw 1124 .wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ +v+ +++s+++ LkP t Y++rV+A n++G++++S KIAA1514 1125 aLHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGdSEFS 1165 PF00041.11.fs: domain 9 of 13, from 1080 to 1165: score 60.6, E = 9.4e-17 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpkngge. Ps P ++ +dv++ s+ lsW+p ++g +p+ +Y+++ R + +g KIAA1514 1080 PSRPM-VQQEDVRARSVLLSWEPGSdGLSPVRYYTIQTR-ELPSGRw 1124 .wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++ +v+ +++s+++ LkP t Y++rV+A n++G++++S KIAA1514 1125 aLHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGdSEFS 1165 PF00041.11.ls: domain 10 of 12, from 1178 to 1288: score 55.6, E = 1.6e-13 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ aPt l+vt+ t+ts+ ++W+pP +++ ng + g++++yR+ + KIAA1514 1178 PdEAPTILSVTPHTTTSVLIRWQPPAedkINGILLGFRIRYRELLYE 1224 ge..............wkelt........vpgtttsytltgLkPgteYtv g ++ + ++ ++++ +w elt+ + ++ ++ t+y+l +L+ +++Y++ KIAA1514 1225 GLrgftlrginnpgatWAELTsmysmrnlSRPSLTQYELDNLNKHRRYEI 1274 rVqAvnggG.GpeS<-* r +n++G+Gp S KIAA1514 1275 RMSVYNAVGeGPSS 1288 PF00041.11.fs: domain 10 of 13, from 1178 to 1288: score 53.5, E = 9.8e-15 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ aPt l+vt+ t+ts+ ++W+pP +++ ng + g++++yR+ + KIAA1514 1178 PdEAPTILSVTPHTTTSVLIRWQPPAedkINGILLGFRIRYRELLYE 1224 ge..............wkelt........vpgtttsytltgLkPgteYtv g ++ + ++ ++++ +w elt+ + ++ ++ t+y+l +L+ +++Y++ KIAA1514 1225 GLrgftlrginnpgatWAELTsmysmrnlSRPSLTQYELDNLNKHRRYEI 1274 rVqAvnggG.GpeS<-* r +n++G+Gp S KIAA1514 1275 RMSVYNAVGeGPSS 1288 PF00041.11.ls: domain 11 of 12, from 1300 to 1389: score 80.6, E = 4.4e-21 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ aP+n+ v + t+t l ++W+pP+ ++ ng+i+gY++ +++ KIAA1514 1300 PtAAPRNVVVHGATATQLDVTWEPPPldsQNGDIQGYKIYF-WEAQR 1345 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* g +++ +t+ ++s+ l++L+ +t Y v+V+A n++G+Gp+S KIAA1514 1346 GNltERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGdGPRS 1389 PF00041.11.fs: domain 11 of 13, from 1300 to 1389: score 78.6, E = 6.2e-22 *->P.saPtnltvtdvtstsltlsWspPt...gngpitgYevtyRqpkng P+ aP+n+ v + t+t l ++W+pP+ ++ ng+i+gY++ +++ KIAA1514 1300 PtAAPRNVVVHGATATQLDVTWEPPPldsQNGDIQGYKIYF-WEAQR 1345 ge..wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* g +++ +t+ ++s+ l++L+ +t Y v+V+A n++G+Gp+S KIAA1514 1346 GNltERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGdGPRS 1389 PF00041.11.ls: domain 12 of 12, from 1401 to 1489: score 60.6, E = 4.8e-15 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyR..qpkngg PsaP+ ++++++t+ts+ +sW++P +ng ++gY++ y + +p++g KIAA1514 1401 PSAPSSVKFSELTTTSVNVSWEAPQfPNGILEGYRLVYEpcSPVDGV 1447 e.wkeltvpgttt.sytltgLkPgteYtvrVqAvnggGGpeS<-* ++ ++++v+g++ +++L +g++Y +r++A + +Gpe KIAA1514 1448 SkIVTVDVKGNSPlWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1489 PF00041.11.fs: domain 12 of 13, from 1401 to 1489: score 58.5, E = 3.6e-16 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyR..qpkngg PsaP+ ++++++t+ts+ +sW++P +ng ++gY++ y + +p++g KIAA1514 1401 PSAPSSVKFSELTTTSVNVSWEAPQfPNGILEGYRLVYEpcSPVDGV 1447 e.wkeltvpgttt.sytltgLkPgteYtvrVqAvnggGGpeS<-* ++ ++++v+g++ +++L +g++Y +r++A + +Gpe KIAA1514 1448 SkIVTVDVKGNSPlWLKVKDLAEGVTYRFRIRAKTFTYGPEI 1489 //