hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/smart.HMMs.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-05015933/chunk_1/iprscan-20080502-05015933.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1514 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SM00060 585.2 2.5e-171 12 SM00408 121.4 1e-31 3 SM00409 101.2 1.2e-25 3 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SM00409 1/3 1 75 [. 1 58 [] 22.8 0.049 SM00408 1/3 1 64 [. 1 56 [] 44.5 1.4e-08 SM00409 2/3 85 170 .. 1 58 [] 43.5 2.9e-08 SM00408 2/3 91 159 .. 1 56 [] 55.8 5.5e-12 SM00409 3/3 179 264 .. 1 58 [] 35.0 1e-05 SM00408 3/3 185 253 .. 1 56 [] 21.1 0.035 SM00060 1/12 267 351 .. 1 69 [] 49.5 4.5e-10 SM00060 2/12 367 453 .. 1 69 [] 46.6 3.4e-09 SM00060 3/12 469 557 .. 1 69 [] 33.5 2.9e-05 SM00060 4/12 572 654 .. 1 69 [] 58.2 1e-12 SM00060 5/12 670 757 .. 1 69 [] 38.2 1.1e-06 SM00060 6/12 774 861 .. 1 69 [] 54.4 1.5e-11 SM00060 7/12 877 962 .. 1 69 [] 44.5 1.4e-08 SM00060 8/12 978 1061 .. 1 69 [] 53.8 2.2e-11 SM00060 9/12 1077 1162 .. 1 69 [] 54.6 1.3e-11 SM00060 10/12 1179 1285 .. 1 69 [] 45.8 5.8e-09 SM00060 11/12 1301 1386 .. 1 69 [] 52.0 7.8e-11 SM00060 12/12 1401 1488 .. 1 69 [] 54.2 1.7e-11 Alignments of top-scoring domains: SM00409: domain 1 of 3, from 1 to 75: score 22.8, E = 0.049 *->ppvtvkeGesvtLtC.as.....titWy................... v ++C+a++ ++++itWy++ + ++ +++++ KIAA1514 1 --------KVVDIPCqAKgvpppSITWYkdaavvevekltrfrqrnd 39 ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++L+I+++ p+D+ G ++C a++ +g+++ +t+L V+ KIAA1514 40 ggLQIsGLVPDDT---GMFQCFARnaAGEVQT--STYLAVT 75 SM00408: domain 1 of 3, from 1 to 64: score 44.5, E = 1.4e-08 *->leGqsVtLtCpasgdpvpnItWlk.gkplp..........sgstLti V ++C a g p p+ItW+k+ ++ ++ ++ ++++++ L+i KIAA1514 1 ---KVVDIPCQAKGVPPPSITWYKdAAVVEvekltrfrqrNDGGLQI 44 knvsleDsGlYtCvArNsvg<-* + ++D G+ +C+ArN++g KIAA1514 45 SGLVPDDTGMFQCFARNAAG 64 SM00409: domain 2 of 3, from 85 to 170: score 43.5, E = 2.9e-08 *->pp.vtvkeGesvtLtC.as.....titWy.................. p + tv G sv+L C+ s+ + + itW ++ + +++ + ++ ++ KIAA1514 85 PLdSTVIDGMSVVLACeTSgaprpAITWQkgerilasgsvqlprftp 131 .....LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* +++L I++ +D+ GtYtC at++ g++++ ++ L V KIAA1514 132 lesgsLLIsPTHISDA---GTYTCLATnsRGVDEA--SADLVVW 170 SM00408: domain 2 of 3, from 91 to 159: score 55.8, E = 5.5e-12 *->leGqsVtLtCpasgdpvpnItWlk.gkplp............sgstL + G sV+L C+ sg+p p ItW k++ l++++ + ++ ++ +++L KIAA1514 91 IDGMSVVLACETSGAPRPAITWQKgERILAsgsvqlprftplESGSL 137 tiknvsleDsGlYtCvArNsvg<-* i++ +D+G+YtC+A+Ns g KIAA1514 138 LISPTHISDAGTYTCLATNSRG 159 SM00409: domain 3 of 3, from 179 to 264: score 35.0, E = 1e-05 *->pp.vtvkeGesvtLtC.as...titWy.................... p++++v G +++ C++++++++t + +++ + ++ ++++ + KIAA1514 179 PQdQSVIKGTQASMVCgVThdpRVTIRyiwekdgatlgteshprirl 225 .....LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* +++++L+I++ D GtYtC++ + +g++s +++L+V+ KIAA1514 226 drngsLHIsQTWSGDI---GTYTCRVIsaGGNDSR--SAHLRVR 264 SM00408: domain 3 of 3, from 185 to 253: score 21.1, E = 0.035 *->leGqsVtLtCpasgdpvpnIt..Wlk.gkplp..........sgstL + G+++++ C+++ dp +I+ W k+g l ++++++ + + +++L KIAA1514 185 IKGTQASMVCGVTHDPRVTIRyiWEKdGATLGteshprirldRNGSL 231 tiknvsleDsGlYtCvArNsvg<-* +i+ +D G+YtC++ ++ g KIAA1514 232 HISQTWSGDIGTYTCRVISAGG 253 SM00060: domain 1 of 12, from 267 to 351: score 49.5, E = 4.5e-10 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... P +P++ +++t t ++ ++l+W++P +++++ ++Y+ + KIAA1514 267 PHAPEH---PVATLSTVERR----AINLTWTKPfdgnspLIRYIlem 306 ....................ytltgLkPgaepwteYefrVrAvngndaGe ++++ ++++ +++++ +++t++gL+P Y+fr+ Avn+ +G KIAA1514 307 sennapwtvllasvdpkatsVTVKGLVPA----RSYQFRLCAVND--VGK 350 g<-* g KIAA1514 351 G 351 SM00060: domain 2 of 12, from 367 to 453: score 46.6, E = 3.4e-09 *->PgpPsnptelrvtdvtststsdltsvtlsWepP............iv P +P+ + + ++ t+ s+ ++W+pP++++ ++ +++i+ KIAA1514 367 PTAPPQN--VIASGRTNQ------SIMIQWQPPpeshqngilkgyII 405 gYr....................ytltgLkPgaepwteYefrVrAvngnd +Y + +++ + ++ ++ ++++ l++L + t+Ye+ V+A+n+ KIAA1514 406 RYClaglpvgyqfknitdadvnnLLLEDLIIW----TNYEIEVAAYNS-- 449 aGeg<-* aG g KIAA1514 450 AGLG 453 SM00060: domain 3 of 12, from 469 to 557: score 33.5, E = 2.9e-05 *->PgpPsnptelrvtdvtststsdltsvtlsWepP........ivgYr. pP+n +++++++st +++ +W++P++ ++ gY+ KIAA1514 469 TVPPGN---VHAEATNST------TIRFTWNAPspqfingiNQGYKl 506 ..........................ytltgLkPgaepwteYefrVrAvn ++++++++++ ++ +++ +++ + ++gLk teY +V +++ KIAA1514 507 iawepeqeeevtmvtarpnfqdsihvGFVSGLKKF----TEYFTSVLCFT 552 gndaGeg<-* G g KIAA1514 553 T--PGDG 557 SM00060: domain 4 of 12, from 572 to 654: score 58.2, E = 1e-12 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... Pgp+++ l+++++ +t s+ +sW++P+++++ +gYr ++ KIAA1514 572 PGPVGH---LSFSEILDT------SLKVSWQEPgekngiLTGYRisw 609 ....................ytltgLkPgaepwteYefrVrAvngndaGe ++ ++++++++ ++++ +y++tgL++ t+Y++ V+A ++ +G+ KIAA1514 610 eeynrtntrvthylpnvtleYRVTGLTAL----TTYTIEVAAMTS--KGQ 653 g<-* g KIAA1514 654 G 654 SM00060: domain 5 of 12, from 670 to 757: score 38.2, E = 1.1e-06 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... PgpP+n l +++++++ svtl+ p ++++ +i ++ ++ KIAA1514 670 PGPPTN---LGISNIGPR------SVTLQFRPGydgktsISRWLvea 707 .........................ytltgLkPgaepwteYefrVrAvng +++++++++++ + +++++ ++ +++L P t Y+fr r vn KIAA1514 708 qvgvvgegeewllihqlsnepdarsMEVPDLNPF----TCYSFRMRQVNI 753 ndaGeg<-* +G + KIAA1514 754 --VGTS 757 SM00060: domain 6 of 12, from 774 to 861: score 54.4, E = 1.5e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP..........ivgY +P n ++++ ++t s+ l+W p ++ +++++++ vgY KIAA1514 774 DMAPAN---VSLRTASET------SLWLRWMPLpemeyngnpeSVGY 811 r........................ytltgLkPgaepwteYefrVrAvng + + +++++ +++ + +++++++++yt+++L+++ teY+++V+A+n+ KIAA1514 812 KikysrsdghgktlshvvqdrverdYTIEDLEEW----TEYRVQVQAFNA 857 ndaGeg<-* G+g KIAA1514 858 --IGSG 861 SM00060: domain 7 of 12, from 877 to 962: score 44.5, E = 1.4e-08 *->PgpPsnptelrvtdvtststsdltsvtlsWepP........ivgYr. + P+n +++ ++ts+ s+ ++W++ ++ + ++ ++gY++ KIAA1514 877 SSGPTN---VSALATTSS------SMLVRWSEVpeadrnglVLGYKv 914 .......................ytltgLkPgaepwteYefrVrAvngnd ++++++++++ + +++++++++ ltgL + Ye++V A+++ KIAA1514 915 mykekdsdtqprfwlvegnssrsAQLTGLGKY----VLYEVQVLAFTR-- 958 aGeg<-* G g KIAA1514 959 IGDG 962 SM00060: domain 8 of 12, from 978 to 1061: score 53.8, E = 2.2e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... PgpP + + + +v +t sv+l W+pP +++ i+ Y+ + KIAA1514 978 PGPPMG---ILFPEVRTT------SVRLIWQPPaapngiILAYQith 1015 .....................ytltgLkPgaepwteYefrVrAvngndaG + ++++ ++ ++++ ++ ++yt tgLkP + Y fr++A ++ +G KIAA1514 1016 rlntttantatvevlapsarqYTATGLKPE----SVYLFRITAQTR--KG 1059 eg<-* +g KIAA1514 1060 WG 1061 SM00060: domain 9 of 12, from 1077 to 1162: score 54.6, E = 1.3e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... P pPs+p +++ +dv ++ sv lsWep +++ +++ +Y+ ++ KIAA1514 1077 PQPPSRP-MVQQEDVRAR------SVLLSWEPGsdglspVRYYTiqt 1116 .....................ytltgLkPgaepwteYefrVrAvngndaG ++ +++++ + +++ + ++++++ LkP t Y+frV+A n+ G KIAA1514 1117 relpsgrwalhsasvshnassFIVDRLKPF----TSYKFRVKATND--IG 1160 eg<-* + KIAA1514 1161 DS 1162 SM00060: domain 10 of 12, from 1179 to 1285: score 45.8, E = 5.8e-09 *->PgpPsnptelrvtdvtststsdltsvtlsWepP............iv +P+ l+vt+ t+t sv ++W+pP +++ ++ + ++ KIAA1514 1179 DEAPTI---LSVTPHTTT------SVLIRWQPPaedkingillgfRI 1216 gYr.........................................ytltgL +Yr+ ++ ++ + ++ ++++ ++ + ++ + ++ ++++ ++y l++L KIAA1514 1217 RYRellyeglrgftlrginnpgatwaeltsmysmrnlsrpsltqYELDNL 1266 kPgaepwteYefrVrAvngndaGeg<-* + +Ye+r +++n+ +Geg KIAA1514 1267 NKH----RRYEIRMSVYNA--VGEG 1285 SM00060: domain 11 of 12, from 1301 to 1386: score 52.0, E = 7.8e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP........ivgYr. +P+n ++v+ t+t ++ ++WepP+ ++ +++i gY+ KIAA1514 1301 TAAPRN---VVVHGATAT------QLDVTWEPPpldsqngdIQGYKi 1338 .......................ytltgLkPgaepwteYefrVrAvngnd ++ ++++ ++++++ +++++l++L+ + t Y ++V+A+n+ KIAA1514 1339 yfweaqrgnltervktlflaensVKLKNLTGY----TAYMVSVAAFNA-- 1382 aGeg<-* aG g KIAA1514 1383 AGDG 1386 SM00060: domain 12 of 12, from 1401 to 1488: score 54.2, E = 1.7e-11 *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr... P++Ps +++++ t+t sv++sWe+P +++ gYr + KIAA1514 1401 PSAPSS---VKFSELTTT------SVNVSWEAPqfpngiLEGYRlvy 1438 ........................ytltgLkPgaepwteYefrVrAvngn ++ ++++++++ ++++++++++ + ++++L +g +Y+fr+rA++ KIAA1514 1439 epcspvdgvskivtvdvkgnsplwLKVKDLAEG----VTYRFRIRAKT-F 1483 daGeg<-* +G+ KIAA1514 1484 TYGPE 1488 //