hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-05320507/chunk_1/iprscan-20080502-05320507.nocrc
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Query sequence: KIAA1532
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
PF04258.4.ls   Signal peptide peptidase                 535.4   5.7e-158   1
PF04258.4.fs   Signal peptide peptidase                 533.7   1.9e-157   1
PF02225.12.fs  PA domain                                 62.6    4.3e-18   1
PF02225.12.ls  PA domain                                 64.5    3.2e-16   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
PF02225.12.fs    1/1      64   164 ..     1   111 []    62.6  4.3e-18
PF02225.12.ls    1/1      64   164 ..     1   111 []    64.5  3.2e-16
PF04258.4.fs     1/1     222   512 ..     1   411 []   533.7 1.9e-157
PF04258.4.ls     1/1     222   512 ..     1   411 []   535.4 5.7e-158

Alignments of top-scoring domains:
PF02225.12.fs: domain 1 of 1, from 64 to 164: score 62.6, E = 4.3e-18
                   *->sp.ggktgpLVyagdgsnsdfsaCesrpgsldpkdvkGKIVLcdrGg
                      +p+++ ++++    + ++s   +C+    +l++   ++ I L+ rG+
    KIAA1532    64    LPhDLSKASFLQLRNWTASL--LCS--AADLPARGFSNQIPLVARGN 106  

                   csfaeKaanAqaAGAaGvIiynnpddglevmapetdsndkkdpdshgiPa
                   c+f+eK++ Aq  GA+G++i++ +  +++++        k+++d +giP+
    KIAA1532   107 CTFYEKVRLAQGSGARGLLIVSRERLVPPGGN-------KTQYDEIGIPV 149  

                   vfvskedGeallsyi<-*
                   +++s++d  +++  +   
    KIAA1532   150 ALLSYKDMLDIFTRF    164  

PF02225.12.ls: domain 1 of 1, from 64 to 164: score 64.5, E = 3.2e-16
                   *->sp.ggktgpLVyagdgsnsdfsaCesrpgsldpkdvkGKIVLcdrGg
                      +p+++ ++++    + ++s   +C+    +l++   ++ I L+ rG+
    KIAA1532    64    LPhDLSKASFLQLRNWTASL--LCS--AADLPARGFSNQIPLVARGN 106  

                   csfaeKaanAqaAGAaGvIiynnpddglevmapetdsndkkdpdshgiPa
                   c+f+eK++ Aq  GA+G++i++ +  +++++        k+++d +giP+
    KIAA1532   107 CTFYEKVRLAQGSGARGLLIVSRERLVPPGGN-------KTQYDEIGIPV 149  

                   vfvskedGeallsyi<-*
                   +++s++d  +++  +   
    KIAA1532   150 ALLSYKDMLDIFTRF    164  

PF04258.4.fs: domain 1 of 1, from 222 to 512: score 533.7, E = 1.9e-157
                   *->kskeetetidsrhAiifpisasctLllLylffkslskgkleyinlsk
                      k+++e++++++ ++++f+++++ +L+lLy+f++           l  
    KIAA1532   222    KQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDL----------L-- 256  

                   svddditsltidsgtkvfllllgslitilsmmaswivlvLtgyFfvlgai
                                                       v+v++g+F++++a+
    KIAA1532   257 ------------------------------------VYVVIGIFCLASAT 270  

                   gatnAllflilppvirrlsfmpairsflsnkklyrfpkkklklHFyrrEl
                   g     l+++l+p++rrl+f+++           r+p+++l++       
    KIAA1532   271 G-----LYSCLAPCVRRLPFGKC-----------RIPNNSLPY------- 297  

                   fttkdgksKeqlifngrftaselvalllcivvaVvWyvlrkedhwAWilq
                                f++r++a++l+++l+c++v+VvW v+r+ed+wAW+lq
    KIAA1532   298 -------------FHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQ 334  

                   DilGialcinvieilrLpnlkvGtlLLsgLFfYDIFWVFiSpyifk.Gts
                   D+lGia+c+++++++rLp++k++tlLL++LF+YDIF+VFi+p+++k+G+s
    KIAA1532   335 DALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKsGSS 384  

                   VMVtVAtgpfDaaegvnkklhlgPierdspreklPmkLvfPrlndyengl
                   +MV+VAtgp+D+a+                reklPm+L++Prln+++++l
    KIAA1532   385 IMVEVATGPSDSAT----------------REKLPMVLKVPRLNSSPLAL 418  

                   DmEienagnfSmLGLGDIVmPGLLiAfclRFDiskkvlshdeieapsgkk
                        ++++fS+LG+GDI++PGLL+A+c+RFDi++              +
    KIAA1532   419 -----CDRPFSLLGFGDILVPGLLVAYCHRFDIQV--------------Q 449  

                   ssrtgYFistmiAYglGLliTfvaLnlfkGaAQPALLYLVPctLgtlllv
                   ssr+ YF++++iAYg+GLl+TfvaL+l++ ++QPALLYLVPctL+t ++v
    KIAA1532   450 SSRV-YFVACTIAYGVGLLVTFVALALMQ-RGQPALLYLVPCTLVTSCAV 497  

                   AlwRgELkklWsyse<-*
                   AlwR+EL ++W++s    
    KIAA1532   498 ALWRRELGVFWTGSG    512  

PF04258.4.ls: domain 1 of 1, from 222 to 512: score 535.4, E = 5.7e-158
                   *->kskeetetidsrhAiifpisasctLllLylffkslskgkleyinlsk
                      k+++e++++++ ++++f+++++ +L+lLy+f++           l  
    KIAA1532   222    KQEDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDL----------L-- 256  

                   svddditsltidsgtkvfllllgslitilsmmaswivlvLtgyFfvlgai
                                                       v+v++g+F++++a+
    KIAA1532   257 ------------------------------------VYVVIGIFCLASAT 270  

                   gatnAllflilppvirrlsfmpairsflsnkklyrfpkkklklHFyrrEl
                   g     l+++l+p++rrl+f+++           r+p+++l++       
    KIAA1532   271 G-----LYSCLAPCVRRLPFGKC-----------RIPNNSLPY------- 297  

                   fttkdgksKeqlifngrftaselvalllcivvaVvWyvlrkedhwAWilq
                                f++r++a++l+++l+c++v+VvW v+r+ed+wAW+lq
    KIAA1532   298 -------------FHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQ 334  

                   DilGialcinvieilrLpnlkvGtlLLsgLFfYDIFWVFiSpyifk.Gts
                   D+lGia+c+++++++rLp++k++tlLL++LF+YDIF+VFi+p+++k+G+s
    KIAA1532   335 DALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKsGSS 384  

                   VMVtVAtgpfDaaegvnkklhlgPierdspreklPmkLvfPrlndyengl
                   +MV+VAtgp+D+a+                reklPm+L++Prln+++++l
    KIAA1532   385 IMVEVATGPSDSAT----------------REKLPMVLKVPRLNSSPLAL 418  

                   DmEienagnfSmLGLGDIVmPGLLiAfclRFDiskkvlshdeieapsgkk
                        ++++fS+LG+GDI++PGLL+A+c+RFDi++              +
    KIAA1532   419 -----CDRPFSLLGFGDILVPGLLVAYCHRFDIQV--------------Q 449  

                   ssrtgYFistmiAYglGLliTfvaLnlfkGaAQPALLYLVPctLgtlllv
                   ssr+ YF++++iAYg+GLl+TfvaL+l++ ++QPALLYLVPctL+t ++v
    KIAA1532   450 SSRV-YFVACTIAYGVGLLVTFVALALMQ-RGQPALLYLVPCTLVTSCAV 497  

                   AlwRgELkklWsyse<-*
                   AlwR+EL ++W++s    
    KIAA1532   498 ALWRRELGVFWTGSG    512  

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