# /usr/local/bin/fasta34 -b50 -d10 -E0.01 -H -O./tmp/fk12792.fasta.huge -Q ../query/KIAA1535.ptfa ./tmplib.25089 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 KIAA1535, 711 aa
 vs ./tmplib.25089 library

1986794 residues in  2037 sequences
  Expectation_n fit: rho(ln(x))= 9.2637+/-0.00958; mu= -2.8760+/- 0.650
 mean_var=387.6823+/-94.473, 0's: 0 Z-trim: 2  B-trim: 8 in 1/39
 Lambda= 0.065138

FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                      opt bits E(2037)
KIAA1282  ( 1117 res)   hh04440b(revised)          (1117)  320 44.7 5.8e-05


>>KIAA1282  ( 1117 res)   hh04440b(revised)               (1117 aa)
 initn: 369 init1: 194 opt: 320  Z-score: 181.0  bits: 44.7 E(): 5.8e-05
Smith-Waterman score: 492;  25.065% identity (49.870% similar) in 770 aa overlap (1-704:229-902)

                                              10        20         
KIAA15                               VFGSHKAV-EIEQERVKSAGAWIIHPYSDF
                                     ::: .  . : .   ....   ..:  . .
KIAA12 ANRRRSRAVLYHLSGHLQKQPKGKHKLNKGVFGEKPNLPEYKVAAIRKSPFILLH-CGAL
      200       210       220       230       240       250        

      30        40          50        60           70        80    
KIAA15 RFYWDLIMLLLMVGNLIVLP--VGITFFKEENS---PPWIVFNVLSDTFFLLDLVLNFRT
       :  :: ..::  .   ...:  : ..  .: ..   ::  : ..  ...:.::.::::::
KIAA12 RATWDGFILLATLYVAVTVPYSVCVSTAREPSAARGPP-SVCDLAVEVLFILDIVLNFRT
       260       270       280       290        300       310      

           90       100       110       120       130       140    
KIAA15 GIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARAL
        .: . : ....::..:  .:. ::::.:.:...: : .         . ..::  :. :
KIAA12 TFVSKSG-QVVFAPKSICLHYVTTWFLLDVIAALPFDLLH-------AFKVNVYFGAHLL
        320        330       340       350              360        

          150       160        170       180       190       200   
KIAA15 RIVRFTKILSLLRLLRL-SRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDG
       . ::      :::::::  :: ::  :.           ::::  . :.... :: :: .
KIAA12 KTVR------LLRLLRLLPRLDRY-SQY-----------SAVVLTL-LMAVFALLAHWVA
      370             380                   390        400         

           210             220                     230             
KIAA15 CLQFLVPMLQ------DFPPDCWV--------SINHMVN------HSWGRQ---------
       :. : . . .      ..:   :.        .  ..:.      .: :..         
KIAA12 CVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGGNSSGQSDNCSSSSEA
     410       420       430       440       450       460         

                          240       250       260       270        
KIAA15 ----------------YSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAM
                       :  .:. :.: .  .:.:. .     .  ... .:..::  .:.
KIAA12 NGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAV
     470       480       490       500       510       520         

      280       290       300       310       320       330        
KIAA15 FIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQ-GKMFDEE
        .:..::.:: . . :  :. . .....:. .:..:   .::. ::..  .  .. .:  
KIAA12 VFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTT
     530       540       550       560       570       580         

       340       350       360       370       380       390       
KIAA15 SILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGS
        .:  : . :: .:     .  : ..:::  :. . . :.   ::     ::. ....:.
KIAA12 ELLQSLPDELRADIAMHLHKE-VLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGD
     590       600       610        620       630       640        

       400       410       420       430       440           450   
KIAA15 VGRKMYFIQHGLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRAD----TYCRLYS
       . . .::.  : . ::  :.  . :  :. .:  : : : ...... ::    ::: :  
KIAA12 ALQALYFVCSGSMEVLKGGTVLAILGKGDLIG--CELPRREQVVKANADVKGLTYCVLQC
      650       660       670       680         690       700      

           460       470       480       490       500       510   
KIAA15 LSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQRKRSEPSPGSSGGIMEQHLVQ
       :..  ..  :  .: .   :     .: :: :. .  :         :..::        
KIAA12 LQLAGLHDSLALYPEFAPRF-----SRGLR-GELSYNL---------GAGGG--------
        710       720            730                 740           

           520       530       540       550       560         570 
KIAA15 HDRDMARGVRGRAPSTGAQLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPL--PLS
                   :    ..:::  .:   : .   ..             ..::   :  
KIAA12 -----------SAEVDTSSLSGDNTLMSTLEEKETDG-------------EQGPTVSPAP
                      750       760                    770         

             580       590       600       610         620         
KIAA15 PDSPATLLARSAWRSAGSPASPLVPVRAGPWASTSRLPAP--PARTLHASLSRAGRSQVS
        : :.. :   .  :..: :. : : :..:     :: .   :.:.  :  ..:: :   
KIAA12 ADEPSSPLLSPGCTSSSSAAKLLSPRRTAP---RPRLGGRGRPGRA-GALKAEAGPS---
     780       790       800          810       820        830     

     630       640       650       660         670       680       
KIAA15 LLGPPPGGGGRRLGPRGRPLSASQPSLPQRATG--DGSPGRKGTGSERLPPSGLLAKPPR
         .:: .  : :: :   : ..     :. . :  ::  . .   : :.  ::     :.
KIAA12 --APPRALEGLRLPP--MPWNVPPDLSPRVVDGIEDGCGSDQPKFSFRVGQSG-----PE
              840         850       860       870       880        

       690       700          710                                  
KIAA15 TAQPPRPPVPEPA---TPRGLQLSANM                                 
        .. : :  :: .   .:.:                                        
KIAA12 CSSSPSPG-PESGLLTVPHGPSEARNTDTLDKLRQAVTELSEQVLQMREGLQSLRQAVQL
           890        900       910       920       930       940  




711 residues in 1 query   sequences
1986794 residues in 2037 library sequences
 Scomplib [34.26]
 start: Thu Dec 18 15:07:08 2008 done: Thu Dec 18 15:07:09 2008
 Total Scan time:  0.530 Total Display time:  0.040

Function used was FASTA [version 34.26.5 April 26, 2007]