# /hgtech/tools/fasta-34.26.5_v890/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/ff03434.fasta.nr -Q ../query/KIAA1550.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 KIAA1550, 1462 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7825837 sequences Expectation_n fit: rho(ln(x))= 4.9751+/-0.000184; mu= 16.3104+/- 0.010 mean_var=74.8326+/-14.515, 0's: 41 Z-trim: 52 B-trim: 13 in 1/65 Lambda= 0.148262 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 40, opt: 28, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|108860890|sp|Q9HCM2.4|PLXA4_HUMAN RecName: Full (1894) 9859 2119.5 0 gi|114615994|ref|XP_519389.2| PREDICTED: plexin A4 (1896) 9827 2112.7 0 gi|114615996|ref|XP_001136153.1| PREDICTED: plexin (1893) 9822 2111.6 0 gi|194209904|ref|XP_001498318.2| PREDICTED: plexin (1893) 9757 2097.7 0 gi|114615998|ref|XP_001135989.1| PREDICTED: plexin (1904) 9729 2091.7 0 gi|73975510|ref|XP_539370.2| PREDICTED: similar to (1893) 9725 2090.9 0 gi|119891353|ref|XP_618046.3| PREDICTED: putative (1893) 9713 2088.3 0 gi|148681758|gb|EDL13705.1| plexin A4, isoform CRA (1890) 9712 2088.1 0 gi|171543899|ref|NP_786926.2| plexin A4 [Mus muscu (1893) 9712 2088.1 0 gi|28200903|dbj|BAC56599.1| plexin-A4 [Mus musculu (1890) 9690 2083.4 0 gi|108860891|sp|Q80UG2.2|PLXA4_MOUSE RecName: Full (1893) 9690 2083.4 0 gi|73975508|ref|XP_856508.1| PREDICTED: similar to (1896) 9656 2076.1 0 gi|73975506|ref|XP_856468.1| PREDICTED: similar to (1896) 9655 2075.9 0 gi|126340703|ref|XP_001367207.1| PREDICTED: simila (1895) 9225 1983.9 0 gi|148681757|gb|EDL13704.1| plexin A4, isoform CRA (1361) 9014 1938.7 0 gi|149065213|gb|EDM15289.1| plexin A4 (predicted) (1340) 8882 1910.4 0 gi|82085272|sp|Q6BEA0.1|PLXA4_DANRE RecName: Full= (1903) 8074 1737.7 0 gi|56207475|emb|CAI21292.1| plexin A4 [Danio rerio (1903) 8073 1737.5 0 gi|118081941|ref|XP_425513.2| PREDICTED: similar t (1879) 7948 1710.8 0 gi|189536136|ref|XP_689780.3| PREDICTED: similar t (1912) 7181 1546.7 0 gi|109018434|ref|XP_001110980.1| PREDICTED: simila (1895) 7174 1545.2 0 gi|171846959|gb|AAI61575.1| Plxna2 protein [Xenopu (1898) 7169 1544.1 0 gi|194674254|ref|XP_584652.4| PREDICTED: plexin A2 (1894) 7167 1543.7 0 gi|149708603|ref|XP_001491498.1| PREDICTED: plexin (1894) 7153 1540.7 0 gi|118102445|ref|XP_417985.2| PREDICTED: similar t (1893) 7150 1540.1 0 gi|187952395|gb|AAI36531.1| Plexin A2 [Homo sapien (1894) 7147 1539.4 0 gi|57162384|emb|CAI40198.1| plexin A2 [Homo sapien (1894) 7147 1539.4 0 gi|215274218|sp|O75051.3|PLXA2_HUMAN RecName: Full (1909) 7147 1539.4 0 gi|168267376|dbj|BAG09744.1| plexin-A2 precursor [ (1909) 7147 1539.4 0 gi|109018432|ref|XP_001110951.1| PREDICTED: simila (1894) 7146 1539.2 0 gi|73960731|ref|XP_547389.2| PREDICTED: similar to (1909) 7134 1536.7 0 gi|148680991|gb|EDL12938.1| plexin A2, isoform CRA (1911) 7124 1534.5 0 gi|81861617|sp|P70207.1|PLXA2_MOUSE RecName: Full= (1884) 7121 1533.9 0 gi|45768339|gb|AAH68155.1| Plexin A2 [Mus musculus (1884) 7121 1533.9 0 gi|113722113|ref|NP_032908.2| plexin A2 [Mus muscu (1894) 7121 1533.9 0 gi|73975504|ref|XP_856429.1| PREDICTED: similar to (1914) 7051 1518.9 0 gi|126340705|ref|XP_001367253.1| PREDICTED: simila (1881) 6826 1470.8 0 gi|109018436|ref|XP_001110877.1| PREDICTED: simila (1817) 6770 1458.8 0 gi|162317992|gb|AAI56130.1| Plexin A1 [synthetic c (1873) 6731 1450.4 0 gi|194228514|ref|XP_001918209.1| PREDICTED: plexin (1894) 6731 1450.5 0 gi|119599757|gb|EAW79351.1| plexin A1, isoform CRA (1896) 6731 1450.5 0 gi|93140549|sp|Q9UIW2.2|PLXA1_HUMAN RecName: Full= (1896) 6731 1450.5 0 gi|168278112|dbj|BAG11034.1| plexin-A1 precursor [ (1914) 6731 1450.5 0 gi|109033579|ref|XP_001114446.1| PREDICTED: simila (1873) 6727 1449.6 0 gi|54311211|gb|AAH84782.1| LOC495321 protein [Xeno (1886) 6718 1447.7 0 gi|109473842|ref|XP_001072622.1| PREDICTED: simila (1894) 6718 1447.7 0 gi|149036710|gb|EDL91328.1| rCG56095 [Rattus norve (1912) 6718 1447.7 0 gi|81861616|sp|P70206.1|PLXA1_MOUSE RecName: Full= (1894) 6705 1444.9 0 gi|148666850|gb|EDK99266.1| plexin A1 [Mus musculu (1912) 6705 1444.9 0 gi|190340068|gb|AAI63880.1| Plexin A3 [Danio rerio (1892) 6644 1431.8 0 >>gi|108860890|sp|Q9HCM2.4|PLXA4_HUMAN RecName: Full=Ple (1894 aa) initn: 9859 init1: 9859 opt: 9859 Z-score: 11384.7 bits: 2119.5 E(): 0 Smith-Waterman score: 9859; 100.000% identity (100.000% similar) in 1462 aa overlap (1-1462:433-1894) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|108 NFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 410 420 430 440 450 460 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS 470 480 490 500 510 520 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 530 540 550 560 570 580 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 590 600 610 620 630 640 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP 650 660 670 680 690 700 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC 710 720 730 740 750 760 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA 770 780 790 800 810 820 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN 830 840 850 860 870 880 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 890 900 910 920 930 940 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 950 960 970 980 990 1000 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|108 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1850 1860 1870 1880 1890 >>gi|114615994|ref|XP_519389.2| PREDICTED: plexin A4, A (1896 aa) initn: 7211 init1: 7211 opt: 9827 Z-score: 11347.7 bits: 2112.7 E(): 0 Smith-Waterman score: 9827; 99.523% identity (99.659% similar) in 1467 aa overlap (1-1462:430-1896) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|114 NFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 400 410 420 430 440 450 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS 460 470 480 490 500 510 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 520 530 540 550 560 570 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 580 590 600 610 620 630 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP 640 650 660 670 680 690 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC 700 710 720 730 740 750 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA 760 770 780 790 800 810 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::::::::::::::::::.:::::::.:::::::::::::::::::::::::::::: gi|114 CGWCQGPGQCTLRQHCPAQESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 820 830 840 850 860 870 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 880 890 900 910 920 930 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 940 950 960 970 980 990 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1000 1010 1020 1030 1040 1050 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1060 1070 1080 1090 1100 1110 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1120 1130 1140 1150 1160 1170 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1180 1190 1200 1210 1220 1230 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1240 1250 1260 1270 1280 1290 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1300 1310 1320 1330 1340 1350 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1360 1370 1380 1390 1400 1410 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1420 1430 1440 1450 1460 1470 1060 1070 1080 1090 1100 KIAA15 YSLSEDKLIRQQIDYKTLV-----LSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIF ::::::::::::::::::: :::::::::::::::::::::::::::::::::::: gi|114 YSLSEDKLIRQQIDYKTLVSPPIFLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIF 1480 1490 1500 1510 1520 1530 1110 1120 1130 1140 1150 1160 KIAA15 KNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 KNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVAL 1540 1550 1560 1570 1580 1590 1170 1180 1190 1200 1210 1220 KIAA15 VSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKN 1600 1610 1620 1630 1640 1650 1230 1240 1250 1260 1270 1280 KIAA15 HEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 HEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMF 1660 1670 1680 1690 1700 1710 1290 1300 1310 1320 1330 1340 KIAA15 DFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 DFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQT 1720 1730 1740 1750 1760 1770 1350 1360 1370 1380 1390 1400 KIAA15 FMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 FMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQS 1780 1790 1800 1810 1820 1830 1410 1420 1430 1440 1450 1460 KIAA15 RMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1840 1850 1860 1870 1880 1890 >>gi|114615996|ref|XP_001136153.1| PREDICTED: plexin A4, (1893 aa) initn: 9822 init1: 7206 opt: 9822 Z-score: 11341.9 bits: 2111.6 E(): 0 Smith-Waterman score: 9822; 99.590% identity (99.795% similar) in 1464 aa overlap (1-1462:430-1893) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|114 NFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 400 410 420 430 440 450 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS 460 470 480 490 500 510 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 520 530 540 550 560 570 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 580 590 600 610 620 630 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP 640 650 660 670 680 690 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC 700 710 720 730 740 750 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA 760 770 780 790 800 810 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::::::::::::::::::.:::::::.:::::::::::::::::::::::::::::: gi|114 CGWCQGPGQCTLRQHCPAQESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 820 830 840 850 860 870 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 880 890 900 910 920 930 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 940 950 960 970 980 990 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1000 1010 1020 1030 1040 1050 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1060 1070 1080 1090 1100 1110 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1120 1130 1140 1150 1160 1170 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1180 1190 1200 1210 1220 1230 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1240 1250 1260 1270 1280 1290 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1300 1310 1320 1330 1340 1350 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1360 1370 1380 1390 1400 1410 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1420 1430 1440 1450 1460 1470 1060 1070 1080 1090 1100 KIAA15 YSLSEDKLIRQQIDYKTL--VLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNV :::::::::::::::::: .: ::::::::::::::::::::::::::::::::::::: gi|114 YSLSEDKLIRQQIDYKTLCTTLHCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNV 1480 1490 1500 1510 1520 1530 1110 1120 1130 1140 1150 1160 KIAA15 PCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSK 1540 1550 1560 1570 1580 1590 1170 1180 1190 1200 1210 1220 KIAA15 QVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 QVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEH 1600 1610 1620 1630 1640 1650 1230 1240 1250 1260 1270 1280 KIAA15 GDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFL 1660 1670 1680 1690 1700 1710 1290 1300 1310 1320 1330 1340 KIAA15 DEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 DEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMD 1720 1730 1740 1750 1760 1770 1350 1360 1370 1380 1390 1400 KIAA15 SCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMH 1780 1790 1800 1810 1820 1830 1410 1420 1430 1440 1450 1460 KIAA15 MNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 MNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1840 1850 1860 1870 1880 1890 >>gi|194209904|ref|XP_001498318.2| PREDICTED: plexin A4 (1893 aa) initn: 9757 init1: 9757 opt: 9757 Z-score: 11266.8 bits: 2097.7 E(): 0 Smith-Waterman score: 9757; 98.632% identity (99.795% similar) in 1462 aa overlap (1-1462:432-1893) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|194 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 410 420 430 440 450 460 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: gi|194 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCSECLGS 470 480 490 500 510 520 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.:::::::::::::::::::.:::::::::::::::: gi|194 GDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPSNISVSQYNVLLVLETY 530 540 550 560 570 580 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::.:::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|194 NVPELTAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 590 600 610 620 630 640 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP 650 660 670 680 690 700 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC 710 720 730 740 750 760 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFE 770 780 790 800 810 820 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::: .::::::::: .::::::::::.:::::::::::::::::::::::::::::: gi|194 CGWCQGQAQCTLRQHCPIHESQWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 830 840 850 860 870 880 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: gi|194 LGLEFRDIASHVKVAGVDCSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 890 900 910 920 930 940 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: gi|194 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCVFHRRSPS 950 960 970 980 990 1000 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: gi|194 YIVCNTTSSDEVLEMKVTVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL ::::::::::::::::::::::.:::::.::::::::::::::::::::::::::::::: gi|194 THLDLIQNPQIRAKHGGKEHINLCEVLNSTEMTCQAPALALGPDHQSDLTERPEEFGFIL 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: gi|194 VLVGEKPCTVTVSDAQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::::::::::::.::.::::::::::::::::::::::::::::::::: gi|194 YSLSEDKLIRQQIDYKTLVLSCVNPDSANSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: gi|194 SHRPKAADMDLEWRQGSGVRMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1850 1860 1870 1880 1890 >>gi|114615998|ref|XP_001135989.1| PREDICTED: plexin A4, (1904 aa) initn: 7125 init1: 6982 opt: 9729 Z-score: 11234.4 bits: 2091.7 E(): 0 Smith-Waterman score: 9729; 98.441% identity (98.780% similar) in 1475 aa overlap (1-1462:430-1904) 10 20 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVD- :::::::::::::::::::::::::: . gi|114 NFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKILMRL 400 410 420 430 440 450 30 40 50 60 70 80 KIAA15 ------GPRGN-ALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQ .: : :. ::::::::::::::::::::::::::::::::::::::::::::: gi|114 RQKNHLNPGGRPAMVYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQ 460 470 480 490 500 510 90 100 110 120 130 140 KIAA15 SCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYN 520 530 540 550 560 570 150 160 170 180 190 200 KIAA15 VLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQ 580 590 600 610 620 630 210 220 230 240 250 260 KIAA15 LQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGR 640 650 660 670 680 690 270 280 290 300 310 320 KIAA15 VKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALR 700 710 720 730 740 750 330 340 350 360 370 380 KIAA15 FNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 FNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLC 760 770 780 790 800 810 390 400 410 420 430 440 KIAA15 LKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGT :::::::::::::::::::::::::::::.:::::::.:::::::::::::::::::::: gi|114 LKADPDFACGWCQGPGQCTLRQHCPAQESRWLELSGANSKCTNPRITEIIPVTGPREGGT 820 830 840 850 860 870 450 460 470 480 490 500 KIAA15 KVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 KVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICV 880 890 900 910 920 930 510 520 530 540 550 560 KIAA15 AVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 AVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC 940 950 960 970 980 990 570 580 590 600 610 620 KIAA15 LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSG 1000 1010 1020 1030 1040 1050 630 640 650 660 670 680 KIAA15 NTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTER 1060 1070 1080 1090 1100 1110 690 700 710 720 730 740 KIAA15 PEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAG 1120 1130 1140 1150 1160 1170 750 760 770 780 790 800 KIAA15 GNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPL 1180 1190 1200 1210 1220 1230 810 820 830 840 850 860 KIAA15 SLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFA 1240 1250 1260 1270 1280 1290 870 880 890 900 910 920 KIAA15 ELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKL 1300 1310 1320 1330 1340 1350 930 940 950 960 970 980 KIAA15 FAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 FAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLID 1360 1370 1380 1390 1400 1410 990 1000 1010 1020 1030 1040 KIAA15 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 KNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPI 1420 1430 1440 1450 1460 1470 1050 1060 1070 1080 1090 KIAA15 DAITGEARYSLSEDKLIRQQIDYKTLV-----LSCVSPDNANSPEVPVKILNCDTITQVK ::::::::::::::::::::::::::: :::::::::::::::::::::::::::: gi|114 DAITGEARYSLSEDKLIRQQIDYKTLVSPPIFLSCVSPDNANSPEVPVKILNCDTITQVK 1480 1490 1500 1510 1520 1530 1100 1110 1120 1130 1140 1150 KIAA15 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV 1540 1550 1560 1570 1580 1590 1160 1170 1180 1190 1200 1210 KIAA15 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV 1600 1610 1620 1630 1640 1650 1220 1230 1240 1250 1260 1270 KIAA15 KMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 KMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSAL 1660 1670 1680 1690 1700 1710 1280 1290 1300 1310 1320 1330 KIAA15 PLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDA 1720 1730 1740 1750 1760 1770 1340 1350 1360 1370 1380 1390 KIAA15 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDM 1780 1790 1800 1810 1820 1830 1400 1410 1420 1430 1440 1450 KIAA15 NAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITL 1840 1850 1860 1870 1880 1890 1460 KIAA15 MSLDS ::::: gi|114 MSLDS 1900 >>gi|73975510|ref|XP_539370.2| PREDICTED: similar to ple (1893 aa) initn: 9725 init1: 9725 opt: 9725 Z-score: 11229.8 bits: 2090.9 E(): 0 Smith-Waterman score: 9725; 98.153% identity (99.726% similar) in 1462 aa overlap (1-1462:432-1893) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|739 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 410 420 430 440 450 460 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS ::::::::::::::::::::::::::::::::::::::::::::::::.::.::.::::: gi|739 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCSQYRSCSECLGS 470 480 490 500 510 520 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.:::::::::::::::::::.:::::::::::::::: gi|739 GDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPSNISVSQYNVLLVLETY 530 540 550 560 570 580 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 590 600 610 620 630 640 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: gi|739 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKVPEDCP 650 660 670 680 690 700 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::.:.:::.:::::::::::::::: gi|739 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECVLSIQGNEQRVPALRFNSSSVQC 710 720 730 740 750 760 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFQ 770 780 790 800 810 820 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::. ::::::::::..::::::::::.:.:::::::::::::::::::::::::::: gi|739 CGWCQSQGQCTLRQHCPVHESQWLELSGANSRCTNPRITEIIPVTGPREGGTKVTIRGEN 830 840 850 860 870 880 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 890 900 910 920 930 940 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: gi|739 ARSSQLYYFMTLTLSDLKPKRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 950 960 970 980 990 1000 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG ::.:::::::::::::: ::::.:.::::: ::::::::::::::::::::::::::::: gi|739 YIICNTTSSDEVLEMKVMVQVDKASIHQDLFFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: gi|739 THLDLIQNPQIRAKHGGKEHINLCEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: gi|739 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYVAPDSPLSLPAIVSI 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 AVAGGLLVIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|739 YSLSEDKLIRQQIDYKTLVLSCVNPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::.:::::::::::::::::::::::::::::::::::::::::::::::: gi|739 EFNAMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1850 1860 1870 1880 1890 >>gi|119891353|ref|XP_618046.3| PREDICTED: putative plex (1893 aa) initn: 9713 init1: 9713 opt: 9713 Z-score: 11215.9 bits: 2088.3 E(): 0 Smith-Waterman score: 9713; 98.222% identity (99.658% similar) in 1462 aa overlap (1-1462:432-1893) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|119 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 410 420 430 440 450 460 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS ::::::::::::::.:::::::::::::.:::::::::::::::::::::::::.::::: gi|119 PRGNALQYETVQVVEPGPVLRDMAFSKDREQLYIMSERQLTRVPVESCGQYQSCSECLGS 470 480 490 500 510 520 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.::::::::.::::::::::.:::::::::::::::: gi|119 GDPHCGWCVLHNTCTRKERCERSREPRRFASEVKQCVRLTVHPSNISVSQYNVLLVLETY 530 540 550 560 570 580 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::.:::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|119 NVPELTAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 590 600 610 620 630 640 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::..::::::::::::::: gi|119 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPRSCSFQEGRVKLPEDCP 650 660 670 680 690 700 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|119 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECVLNIQGSEQRVPALRFNSSSVQC 710 720 730 740 750 760 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFE 770 780 790 800 810 820 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::. ::::::::::..::::::::...:::::::::::::::::::::::::::::: gi|119 CGWCQSQGQCTLRQHCPVHESQWLELSSTNSKCTNPRITEIIPVTGPREGGTKVTIRGEN 830 840 850 860 870 880 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 890 900 910 920 930 940 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: gi|119 ARSSQLYYFMTLTLSDLKPSRGPRSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 950 960 970 980 990 1000 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG :::::::::::::::::.:::::::::::: ::::::::::::::::::::::::::::: gi|119 YIVCNTTSSDEVLEMKVTVQVDRAKIHQDLFFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: gi|119 THLDLIQNPQIRAKHGGKEHINLCEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::: ::::::::::::::.:::::::::::::::::::::::::::::::::: gi|119 DNVQSLLILNMTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|119 YSLSEDKLIRQQIDYKTLVLSCVNPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|119 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1850 1860 1870 1880 1890 >>gi|148681758|gb|EDL13705.1| plexin A4, isoform CRA_b [ (1890 aa) initn: 9712 init1: 9712 opt: 9712 Z-score: 11214.7 bits: 2088.1 E(): 0 Smith-Waterman score: 9712; 98.153% identity (99.795% similar) in 1462 aa overlap (1-1462:429-1890) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|148 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 400 410 420 430 440 450 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :.::::::::::::: :::::::::::::::::::::::::::::::::::.:::::::: gi|148 PKGNALQYETVQVVDSGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYRSCGECLGS 460 470 480 490 500 510 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|148 GDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 520 530 540 550 560 570 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|148 NVPELSAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 580 590 600 610 620 630 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: gi|148 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPNTCSFQEGRVKLPEDCP 640 650 660 670 680 690 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: gi|148 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGIEQRVPALRFNSSSVQC 700 710 720 730 740 750 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: gi|148 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVYLYKCGAMRESCGLCLKADPDFE 760 770 780 790 800 810 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::.::::::::::::.::.:::::::.:::::::::::::::::::::::::::::: gi|148 CGWCQSPGQCTLRQHCPAHESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 820 830 840 850 860 870 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 880 890 900 910 920 930 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS ::::::::::::::.::::.::::::::::::::::::::::::::::.::::::::::: gi|148 ARSSQLYYFMTLTLADLKPNRGPMSGGTQVTITGTNLNAGSNVVVMFGSQPCLFHRRSPS 940 950 960 970 980 990 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG ::.::::::.:::.:::.::::::.:.::::::::::::::::::::::::::::::::: gi|148 YIICNTTSSEEVLDMKVTVQVDRARIRQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1000 1010 1020 1030 1040 1050 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1060 1070 1080 1090 1100 1110 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: gi|148 DNVQSLLILNKTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1120 1130 1140 1150 1160 1170 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1180 1190 1200 1210 1220 1230 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1240 1250 1260 1270 1280 1290 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1300 1310 1320 1330 1340 1350 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1360 1370 1380 1390 1400 1410 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1420 1430 1440 1450 1460 1470 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::.:::::::::::::.:::::::::::::::::::::::::::::::: gi|148 YSLSEDKLIRQQIEYKTLVLSCVSPDNVNSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1480 1490 1500 1510 1520 1530 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|148 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTVAHYQVPDGSVVALVSKQV 1540 1550 1560 1570 1580 1590 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: gi|148 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKLWHLVKNHEHGD 1600 1610 1620 1630 1640 1650 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1660 1670 1680 1690 1700 1710 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1720 1730 1740 1750 1760 1770 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1780 1790 1800 1810 1820 1830 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1840 1850 1860 1870 1880 1890 >>gi|171543899|ref|NP_786926.2| plexin A4 [Mus musculus] (1893 aa) initn: 9712 init1: 9712 opt: 9712 Z-score: 11214.7 bits: 2088.1 E(): 0 Smith-Waterman score: 9712; 98.153% identity (99.795% similar) in 1462 aa overlap (1-1462:432-1893) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|171 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 410 420 430 440 450 460 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :.::::::::::::: :::::::::::::::::::::::::::::::::::.:::::::: gi|171 PKGNALQYETVQVVDSGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYRSCGECLGS 470 480 490 500 510 520 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|171 GDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 530 540 550 560 570 580 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|171 NVPELSAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 590 600 610 620 630 640 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: gi|171 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPNTCSFQEGRVKLPEDCP 650 660 670 680 690 700 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: gi|171 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGIEQRVPALRFNSSSVQC 710 720 730 740 750 760 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: gi|171 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVYLYKCGAMRESCGLCLKADPDFE 770 780 790 800 810 820 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::.::::::::::::.::.:::::::.:::::::::::::::::::::::::::::: gi|171 CGWCQSPGQCTLRQHCPAHESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 830 840 850 860 870 880 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 890 900 910 920 930 940 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS ::::::::::::::.::::.::::::::::::::::::::::::::::.::::::::::: gi|171 ARSSQLYYFMTLTLADLKPNRGPMSGGTQVTITGTNLNAGSNVVVMFGSQPCLFHRRSPS 950 960 970 980 990 1000 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG ::.::::::.:::.:::.::::::.:.::::::::::::::::::::::::::::::::: gi|171 YIICNTTSSEEVLDMKVTVQVDRARIRQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1010 1020 1030 1040 1050 1060 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1070 1080 1090 1100 1110 1120 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: gi|171 DNVQSLLILNKTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1130 1140 1150 1160 1170 1180 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1190 1200 1210 1220 1230 1240 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1250 1260 1270 1280 1290 1300 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1310 1320 1330 1340 1350 1360 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1370 1380 1390 1400 1410 1420 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1430 1440 1450 1460 1470 1480 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::.:::::::::::::.:::::::::::::::::::::::::::::::: gi|171 YSLSEDKLIRQQIEYKTLVLSCVSPDNVNSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1490 1500 1510 1520 1530 1540 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|171 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTVAHYQVPDGSVVALVSKQV 1550 1560 1570 1580 1590 1600 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: gi|171 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKLWHLVKNHEHGD 1610 1620 1630 1640 1650 1660 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1670 1680 1690 1700 1710 1720 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1730 1740 1750 1760 1770 1780 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1790 1800 1810 1820 1830 1840 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|171 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1850 1860 1870 1880 1890 >>gi|28200903|dbj|BAC56599.1| plexin-A4 [Mus musculus] (1890 aa) initn: 9690 init1: 9690 opt: 9690 Z-score: 11189.3 bits: 2083.4 E(): 0 Smith-Waterman score: 9690; 98.016% identity (99.658% similar) in 1462 aa overlap (1-1462:429-1890) 10 20 30 KIAA15 TSVIAYVYKNHSLAFVGTKSGKLKKIRVDG :::::::::::::::::::::::::::::: gi|282 NFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDG 400 410 420 430 440 450 40 50 60 70 80 90 KIAA15 PRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGS :.::::::::::::: :::::::::::::::::::::::::::::::::::.:::::::: gi|282 PKGNALQYETVQVVDSGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYRSCGECLGS 460 470 480 490 500 510 100 110 120 130 140 150 KIAA15 GDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|282 GDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETY 520 530 540 550 560 570 160 170 180 190 200 210 KIAA15 NVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|282 NVPELSAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKET 580 590 600 610 620 630 220 230 240 250 260 270 KIAA15 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCP ::::::::::::::::::::::::::::::::::::::::: .:::::::::::::::: gi|282 GMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHGRNTCSFQEGRVKLPEDCP 640 650 660 670 680 690 280 290 300 310 320 330 KIAA15 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQC ::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::: gi|282 QLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGIEQRVPALRFNSSSVQC 700 710 720 730 740 750 340 350 360 370 380 390 KIAA15 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFA :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: gi|282 QNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVYLYKCGAMRESCGLCLKADPDFE 760 770 780 790 800 810 400 410 420 430 440 450 KIAA15 CGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGEN :::::.::::::::::::.::.:::::::.:::::::::::::::::::::::::::::: gi|282 CGWCQSPGQCTLRQHCPAHESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGEN 820 830 840 850 860 870 460 470 480 490 500 510 KIAA15 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 LGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFM 880 890 900 910 920 930 520 530 540 550 560 570 KIAA15 ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS ::::::::::::::.::::.::::::::::::::::::::::::::::.::::::::::: gi|282 ARSSQLYYFMTLTLADLKPNRGPMSGGTQVTITGTNLNAGSNVVVMFGSQPCLFHRRSPS 940 950 960 970 980 990 580 590 600 610 620 630 KIAA15 YIVCNTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG ::.::::::.:::.:::.::::::.:.::::::::::::::::::::::::::::::::: gi|282 YIICNTTSSEEVLDMKVTVQVDRARIRQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWG 1000 1010 1020 1030 1040 1050 640 650 660 670 680 690 KIAA15 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 THLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFIL 1060 1070 1080 1090 1100 1110 700 710 720 730 740 750 KIAA15 DNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: gi|282 DNVQSLLILNKTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYT 1120 1130 1140 1150 1160 1170 760 770 780 790 800 810 KIAA15 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 VLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSI 1180 1190 1200 1210 1220 1230 820 830 840 850 860 870 KIAA15 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 AVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHE 1240 1250 1260 1270 1280 1290 880 890 900 910 920 930 KIAA15 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 LTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNK 1300 1310 1320 1330 1340 1350 940 950 960 970 980 990 KIAA15 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 VFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNH 1360 1370 1380 1390 1400 1410 1000 1010 1020 1030 1040 1050 KIAA15 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 PKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEAR 1420 1430 1440 1450 1460 1470 1060 1070 1080 1090 1100 1110 KIAA15 YSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPC :::::::::::::.:::::::::::::.:::::::::::::::::::::::::::::::: gi|282 YSLSEDKLIRQQIEYKTLVLSCVSPDNVNSPEVPVKILNCDTITQVKEKILDAIFKNVPC 1480 1490 1500 1510 1520 1530 1120 1130 1140 1150 1160 1170 KIAA15 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQV :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|282 SHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTVAHYQVPDGSVVALVSKQV 1540 1550 1560 1570 1580 1590 1180 1190 1200 1210 1220 1230 KIAA15 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGD ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: gi|282 TAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKLWHLVKNHEHGD 1600 1610 1620 1630 1640 1650 1240 1250 1260 1270 1280 1290 KIAA15 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDE 1660 1670 1680 1690 1700 1710 1300 1310 1320 1330 1340 1350 KIAA15 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 QADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSC 1720 1730 1740 1750 1760 1770 1360 1370 1380 1390 1400 1410 KIAA15 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 STSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMN 1780 1790 1800 1810 1820 1830 1420 1430 1440 1450 1460 KIAA15 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS :::::::::::::::::::::::::::::::::::::::::::::::::::: gi|282 EFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1840 1850 1860 1870 1880 1890 1462 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (8 proc) start: Thu Mar 5 02:01:09 2009 done: Thu Mar 5 02:04:50 2009 Total Scan time: 1901.110 Total Display time: 1.860 Function used was FASTA [version 34.26.5 April 26, 2007]