hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-06331746/chunk_1/iprscan-20080502-06331746.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1568 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07679.6.ls Immunoglobulin I-set domain 372.5 6.2e-109 5 PF07679.6.fs Immunoglobulin I-set domain 364.8 1.3e-106 6 PF00047.15.ls Immunoglobulin domain 188.7 1.3e-53 5 PF00047.15.fs Immunoglobulin domain 179.4 8.3e-51 5 PF00041.11.fs Fibronectin type III domain 156.0 3.7e-44 3 PF00041.11.ls Fibronectin type III domain 156.2 7.8e-44 3 PF07686.7.fs Immunoglobulin V-set domain 122.2 7e-34 5 PF07686.7.ls Immunoglobulin V-set domain 121.5 2.2e-33 5 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF07679.6.fs 1/6 33 77 .. 1 49 [. 52.2 1.3e-14 PF07679.6.ls 1/5 33 130 .. 1 96 [] 66.1 1e-16 PF00047.15.fs 1/5 47 114 .. 1 65 [] 28.1 5.7e-07 PF00047.15.ls 1/5 47 114 .. 1 65 [] 30.1 7.2e-06 PF07686.7.ls 2/5 134 224 .. 1 141 [] 25.7 0.00013 PF07686.7.fs 2/5 134 224 .. 1 141 [] 24.0 2.6e-06 PF07679.6.ls 2/5 135 223 .. 1 96 [] 46.8 6.8e-11 PF07679.6.fs 3/6 136 223 .. 2 96 .] 44.9 1.7e-12 PF00047.15.ls 2/5 149 207 .. 1 65 [] 35.5 1.7e-07 PF00047.15.fs 2/5 149 207 .. 1 65 [] 33.7 1.7e-08 PF07679.6.fs 4/6 227 312 .. 1 96 [] 113.0 2.4e-32 PF07679.6.ls 3/5 227 312 .. 1 96 [] 114.9 2.2e-31 PF07686.7.ls 3/5 231 313 .. 1 141 [] 14.1 0.0018 PF00047.15.fs 3/5 241 297 .. 1 65 [] 42.4 7.3e-11 PF00047.15.ls 3/5 241 297 .. 1 65 [] 44.2 4.2e-10 PF07686.7.ls 4/5 316 411 .. 1 141 [] 42.6 1.2e-09 PF07679.6.fs 5/6 316 410 .. 1 96 [] 66.2 1.1e-18 PF07679.6.ls 4/5 316 410 .. 1 96 [] 68.1 2.6e-17 PF07686.7.fs 4/5 316 411 .. 1 141 [] 40.9 4.8e-11 PF00047.15.ls 4/5 330 395 .. 1 65 [] 34.9 2.6e-07 PF00047.15.fs 4/5 330 395 .. 1 65 [] 33.1 2.5e-08 PF07686.7.fs 5/5 420 505 .. 1 141 [] 34.0 4.1e-09 PF07679.6.fs 6/6 420 507 .. 1 96 [] 74.7 3.5e-21 PF07686.7.ls 5/5 420 505 .. 1 141 [] 35.7 1.5e-07 PF07679.6.ls 5/5 420 507 .. 1 96 [] 76.6 7.3e-20 PF00047.15.fs 5/5 434 492 .. 1 65 [] 42.1 8.5e-11 PF00047.15.ls 5/5 434 492 .. 1 65 [] 44.0 4.8e-10 PF00041.11.fs 1/3 524 609 .. 1 84 [] 69.0 3.5e-19 PF00041.11.ls 1/3 524 609 .. 1 84 [] 71.0 3.4e-18 PF00041.11.ls 2/3 640 726 .. 1 84 [] 23.4 0.00067 PF00041.11.fs 2/3 650 715 .. 13 74 .. 27.2 3.4e-07 PF00041.11.ls 3/3 738 828 .. 1 84 [] 61.7 2.1e-15 PF00041.11.fs 3/3 738 828 .. 1 84 [] 59.7 1.6e-16 Alignments of top-scoring domains: PF07679.6.fs: domain 1 of 6, from 33 to 77: score 52.2, E = 1.3e-14 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp P+++ +p+dv V+ Ge+ ++ Ck++G P+Pt++W+KdG+ + KIAA1568 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVET---- 75 sd<-* ++ KIAA1568 76 DK 77 PF07679.6.ls: domain 1 of 5, from 33 to 130: score 66.1, E = 1e-16 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvl.l P+++ +p+dv V+ Ge+ ++ Ck++G P+Pt++W+KdG+ + + + KIAA1568 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKdD 79 psdrfkvtydgGsgtytLtIsnv.....qpdDsGkYtCvAtNs.aGeaea p + +++ +L+++++ ++++ + D+G Y+CvA+N + ++ KIAA1568 80 P-RSHRMLLPS----GSLFFLRIvhgrrSKPDEGSYVCVARNYlGEAVSR 124 saeLtV<-* a+L V KIAA1568 125 NASLEV 130 PF00047.15.fs: domain 1 of 5, from 47 to 114: score 28.1, E = 5.7e-07 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt..gvlvtssenngdsty Ge+ tL+C + +g p +t+ W+++g +++++ ++ +s+++ s + KIAA1568 47 GEPTTLNCKA--EGRPTPTIEWYKDGErVEtdKDDPRSHRMLLPSGS 91 qt..sLtitnvtpeDggtYtCvv<-* + + + + ++ D+g+Y Cv+ KIAA1568 92 LFflRIVHGRRSKPDEGSYVCVA 114 PF00047.15.ls: domain 1 of 5, from 47 to 114: score 30.1, E = 7.2e-06 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt..gvlvtssenngdsty Ge+ tL+C + +g p +t+ W+++g +++++ ++ +s+++ s + KIAA1568 47 GEPTTLNCKA--EGRPTPTIEWYKDGErVEtdKDDPRSHRMLLPSGS 91 qt..sLtitnvtpeDggtYtCvv<-* + + + + ++ D+g+Y Cv+ KIAA1568 92 LFflRIVHGRRSKPDEGSYVCVA 114 PF07686.7.ls: domain 2 of 5, from 134 to 224: score 25.7, E = 0.00013 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss + q p+ v+va G+ ++L C++ ++ KIAA1568 134 RDDFRQ-NPT------------DVVVAAGEPAILECQPP---RGH-- 162 ssgtfsiyWyrq.qppgkgpeliiisyysyystsegngtvgerfkgrvtl ++ +iyW +++ + + + e i+ +g KIAA1568 163 --PEPTIYWKKDkVRIDDKEERIS-------------------IRGGK-- 189 sgnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* L Isn + sD G+Y+C+ n+ + +LtV KIAA1568 190 ----------LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVF 224 PF07686.7.fs: domain 2 of 5, from 134 to 224: score 24.0, E = 2.6e-06 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss + q p+ v+va G+ ++L C++ ++ KIAA1568 134 RDDFRQ-NPT------------DVVVAAGEPAILECQPP---RGH-- 162 ssgtfsiyWyrq.qppgkgpeliiisyysyystsegngtvgerfkgrvtl ++ +iyW +++ + + + e i+ +g KIAA1568 163 --PEPTIYWKKDkVRIDDKEERIS-------------------IRGGK-- 189 sgnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* L Isn + sD G+Y+C+ n+ + +LtV KIAA1568 190 ----------LMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVF 224 PF07679.6.ls: domain 2 of 5, from 135 to 223: score 46.8, E = 6.8e-11 *->PkFtqkpkdveVqeGesarfeCk.VtGtPePtVsWfKdGqplssvll F q p dv+V+ Ge+a +eC++ +G+PePt+ W+Kd + KIAA1568 135 DDFRQNPTDVVVAAGEPAILECQpPRGHPEPTIYWKKDKVRID---- 177 psdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeas.aeLt ++ +++ +g +L+Isn ++D+G YtCv tN++Ge +++aeLt KIAA1568 178 -DKEERISIRG----GKLMISNTRKSDAGMYTCVGTNMVGERDSDpAELT 222 V<-* V KIAA1568 223 V 223 PF07679.6.fs: domain 3 of 6, from 136 to 223: score 44.9, E = 1.7e-12 *->kFtqkpkdveVqeGesarfeCk.VtGtPePtVsWfKdGqplssvllp F q p dv+V+ Ge+a +eC++ +G+PePt+ W+Kd + KIAA1568 136 DFRQNPTDVVVAAGEPAILECQpPRGHPEPTIYWKKDKVRID----- 177 sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeas.aeLtV ++ +++ +g +L+Isn ++D+G YtCv tN++Ge +++aeLtV KIAA1568 178 DKEERISIRG----GKLMISNTRKSDAGMYTCVGTNMVGERDSDpAELTV 223 <-* KIAA1568 - - PF00047.15.ls: domain 2 of 5, from 149 to 207: score 35.5, E = 1.7e-07 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq Ge++ L C+ g+p++t++W++++ ++ + ++ s + + KIAA1568 149 GEPAILECQPP-RGHPEPTIYWKKDKVrIDdKEERISIRGGK----- 189 tsLtitnvtpeDggtYtCvv<-* L i+n++++D+g YtCv KIAA1568 190 --LMISNTRKSDAGMYTCVG 207 PF00047.15.fs: domain 2 of 5, from 149 to 207: score 33.7, E = 1.7e-08 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq Ge++ L C+ g+p++t++W++++ ++ + ++ s + + KIAA1568 149 GEPAILECQPP-RGHPEPTIYWKKDKVrIDdKEERISIRGGK----- 189 tsLtitnvtpeDggtYtCvv<-* L i+n++++D+g YtCv KIAA1568 190 --LMISNTRKSDAGMYTCVG 207 PF07679.6.fs: domain 4 of 6, from 227 to 312: score 113.0, E = 2.4e-32 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp P+F+++p +++V e e+++f C+V+G+P+PtV W+Kd+ +l+ KIAA1568 227 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP----- 268 sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV< r +++ ++ +ytL+I++ + D+G+Y C+A+N++G+ easa+LtV KIAA1568 269 --RGRYDIKD---DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 312 -* KIAA1568 - - PF07679.6.ls: domain 3 of 5, from 227 to 312: score 114.9, E = 2.2e-31 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp P+F+++p +++V e e+++f C+V+G+P+PtV W+Kd+ +l+ KIAA1568 227 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLP----- 268 sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV< r +++ ++ +ytL+I++ + D+G+Y C+A+N++G+ easa+LtV KIAA1568 269 --RGRYDIKD---DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 312 -* KIAA1568 - - PF07686.7.ls: domain 3 of 5, from 231 to 313: score 14.1, E = 0.0018 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss ++ q +v e + v+++C+++ +d+ KIAA1568 231 RRPINQ------------------VVLEEEAVEFRCQVQ---GDP-- 254 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls ++ +++W + ++ + ++ gr+ KIAA1568 255 --QP-TVRWKK-DDA--------------DLPR-----------GRYD-- 273 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* k+d++L+I++ + D+GtY C n + +++ +LtV+ KIAA1568 274 ---IKDDYTLRIKKTMSTDEGTYMCIAENR-VGKMEASATLTVR 313 PF00047.15.fs: domain 3 of 5, from 241 to 297: score 42.4, E = 7.3e-11 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq +e v ++C+v g+p++tv+W++++ +l++g + + + KIAA1568 241 EEAVEFRCQV--QGDPQPTVRWKKDDAdLPrGRYDIKDDYT------ 279 tsLtitnvtpeDggtYtCvv<-* L+i+++ + D+gtY+C + KIAA1568 280 --LRIKKTMSTDEGTYMCIA 297 PF00047.15.ls: domain 3 of 5, from 241 to 297: score 44.2, E = 4.2e-10 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq +e v ++C+v g+p++tv+W++++ +l++g + + + KIAA1568 241 EEAVEFRCQV--QGDPQPTVRWKKDDAdLPrGRYDIKDDYT------ 279 tsLtitnvtpeDggtYtCvv<-* L+i+++ + D+gtY+C + KIAA1568 280 --LRIKKTMSTDEGTYMCIA 297 PF07686.7.ls: domain 4 of 5, from 316 to 411: score 42.6, E = 1.2e-09 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss ++ v pr +va+G +vt+pC + +++ KIAA1568 316 PQFVVR--PR------------DQIVAQGRTVTFPCETK---GNP-- 343 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls ++ ++W + ++ l++ ++ + + + r+++s KIAA1568 344 --QP-AVFWQK----EGSQNLLF-------------PNQPQQPNSRCSVS 373 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* ++++ LtI+n+q+sD G Y C+ + ++ + +L V+ KIAA1568 374 PTGD-----LTITNIQRSDAGYYICQALTV-AGSILAKAQLEVT 411 PF07679.6.fs: domain 5 of 6, from 316 to 410: score 66.2, E = 1.1e-18 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKd........Gq P+F+ +p+d+ V+ G +++f C+ +G+P+P V W K ++++ ++q KIAA1568 316 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEgsqnllfpNQ 362 plssvllpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeae p ++ +r++v+ +g LtI n+q++D+G Y C+A aG+ KIAA1568 363 PQQP----NSRCSVSPTG-----DLTITNIQRSDAGYYICQALTVAGSIL 403 asaeLtV<-* a+a+L V KIAA1568 404 AKAQLEV 410 PF07679.6.ls: domain 4 of 5, from 316 to 410: score 68.1, E = 2.6e-17 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKd........Gq P+F+ +p+d+ V+ G +++f C+ +G+P+P V W K ++++ ++q KIAA1568 316 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEgsqnllfpNQ 362 plssvllpsdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeae p ++ +r++v+ +g LtI n+q++D+G Y C+A aG+ KIAA1568 363 PQQP----NSRCSVSPTG-----DLTITNIQRSDAGYYICQALTVAGSIL 403 asaeLtV<-* a+a+L V KIAA1568 404 AKAQLEV 410 PF07686.7.fs: domain 4 of 5, from 316 to 411: score 40.9, E = 4.8e-11 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss ++ v pr +va+G +vt+pC + +++ KIAA1568 316 PQFVVR--PR------------DQIVAQGRTVTFPCETK---GNP-- 343 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls ++ ++W + ++ l++ ++ + + + r+++s KIAA1568 344 --QP-AVFWQK----EGSQNLLF-------------PNQPQQPNSRCSVS 373 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* ++++ LtI+n+q+sD G Y C+ + ++ + +L V+ KIAA1568 374 PTGD-----LTITNIQRSDAGYYICQALTV-AGSILAKAQLEVT 411 PF00047.15.ls: domain 4 of 5, from 330 to 395: score 34.9, E = 2.6e-07 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq G +vt++C+++ g+p++ v+W+++g + + ++q KIAA1568 330 GRTVTFPCETK--GNPQPAVFWQKEGSqNLlFP----------NQPQ 364 t...........sLtitnvtpeDggtYtCvv<-* +++++ + ++++ Ltitn++++D+g+Y C++ KIAA1568 365 QpnsrcsvsptgDLTITNIQRSDAGYYICQA 395 PF00047.15.fs: domain 4 of 5, from 330 to 395: score 33.1, E = 2.5e-08 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq G +vt++C+++ g+p++ v+W+++g + + ++q KIAA1568 330 GRTVTFPCETK--GNPQPAVFWQKEGSqNLlFP----------NQPQ 364 t...........sLtitnvtpeDggtYtCvv<-* +++++ + ++++ Ltitn++++D+g+Y C++ KIAA1568 365 QpnsrcsvsptgDLTITNIQRSDAGYYICQA 395 PF07686.7.fs: domain 5 of 5, from 420 to 505: score 34.0, E = 4.1e-09 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss ++ +++ p+ t a+ g+++L+C+ + +d+ KIAA1568 420 PIILQG--PA------------NQTLAVDGTALLKCKAT---GDP-- 447 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls + i+W + t+++r + r t++ KIAA1568 448 --LP-VISWLK-EGF----------------------TFPGRDP-RATIQ 470 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* +++ L+I+nl+ sD+GtY+C+ + + g+ + Vl KIAA1568 471 EQGT-----LQIKNLRISDTGTYTCVATS----SSGETSWSAVL 505 PF07679.6.fs: domain 6 of 6, from 420 to 507: score 74.7, E = 3.5e-21 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp P ++q p +++ ++ +a + Ck+tG+P P +sW+K G + + KIAA1568 420 PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPG---R 463 sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV< ++r + + g tL I+n ++D G+YtCvAt s+Ge + sa L V KIAA1568 464 DPRATIQEQG-----TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 507 -* KIAA1568 - - PF07686.7.ls: domain 5 of 5, from 420 to 505: score 35.7, E = 1.5e-07 *->qsqvtqepprWGLLLASLfWptsvtvaeGgsvtLpCtysGtfddsss ++ +++ p+ t a+ g+++L+C+ + +d+ KIAA1568 420 PIILQG--PA------------NQTLAVDGTALLKCKAT---GDP-- 447 ssgtfsiyWyrqqppgkgpeliiisyysyystsegngtvgerfkgrvtls + i+W + t+++r + r t++ KIAA1568 448 --LP-VISWLK-EGF----------------------TFPGRDP-RATIQ 470 gnpskgdfsLtIsnlqlsDsGtYyCavsnsnelvfgggtrLtVl<-* +++ L+I+nl+ sD+GtY+C+ + + g+ + Vl KIAA1568 471 EQGT-----LQIKNLRISDTGTYTCVATS----SSGETSWSAVL 505 PF07679.6.ls: domain 5 of 5, from 420 to 507: score 76.6, E = 7.3e-20 *->PkFtqkpkdveVqeGesarfeCkVtGtPePtVsWfKdGqplssvllp P ++q p +++ ++ +a + Ck+tG+P P +sW+K G + + KIAA1568 420 PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPG---R 463 sdrfkvtydgGsgtytLtIsnvqpdDsGkYtCvAtNsaGeaeasaeLtV< ++r + + g tL I+n ++D G+YtCvAt s+Ge + sa L V KIAA1568 464 DPRATIQEQG-----TLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 507 -* KIAA1568 - - PF00047.15.fs: domain 5 of 5, from 434 to 492: score 42.1, E = 8.5e-11 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq +++ L C + +g+p + ++Wl++g + ++ ++ + +++g+ KIAA1568 434 DGTALLKCKA--TGDPLPVISWLKEGFtFPgRDPRATIQEQGT---- 474 tsLtitnvtpeDggtYtCvv<-* L+i+n++ +D+gtYtCv+ KIAA1568 475 --LQIKNLRISDTGTYTCVA 492 PF00047.15.ls: domain 5 of 5, from 434 to 492: score 44.0, E = 4.8e-10 *->GesvtLtCsvsgfgppdvtvtWlrngk.lt.gvlvtssenngdstyq +++ L C + +g+p + ++Wl++g + ++ ++ + +++g+ KIAA1568 434 DGTALLKCKA--TGDPLPVISWLKEGFtFPgRDPRATIQEQGT---- 474 tsLtitnvtpeDggtYtCvv<-* L+i+n++ +D+gtYtCv+ KIAA1568 475 --LQIKNLRISDTGTYTCVA 492 PF00041.11.fs: domain 1 of 3, from 524 to 609: score 69.0, E = 3.5e-19 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpknggew P++P+ ++vtdvt +s+tlsW+p t+g p + Y ++ ++ + + KIAA1568 524 PGPPSKPQVTDVTKNSVTLSWQPGTpGTLPASAYIIEA-FSQ-SVSN 568 keltvpgt..ttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++tv ++ +tt yt++gL+P+t Y + V+A+n +G + +S KIAA1568 569 SWQTVANHvkTTLYTVRGLRPNTIYLFMVRAINPQGlSDPS 609 PF00041.11.ls: domain 1 of 3, from 524 to 609: score 71.0, E = 3.4e-18 *->PsaPtnltvtdvtstsltlsWspPt.gngpitgYevtyRqpknggew P++P+ ++vtdvt +s+tlsW+p t+g p + Y ++ ++ + + KIAA1568 524 PGPPSKPQVTDVTKNSVTLSWQPGTpGTLPASAYIIEA-FSQ-SVSN 568 keltvpgt..ttsytltgLkPgteYtvrVqAvnggG.GpeS<-* ++tv ++ +tt yt++gL+P+t Y + V+A+n +G + +S KIAA1568 569 SWQTVANHvkTTLYTVRGLRPNTIYLFMVRAINPQGlSDPS 609 PF00041.11.ls: domain 2 of 3, from 640 to 726: score 23.4, E = 0.00067 *->PsaPtnltvtdvtstsltlsWspPtgngpitgYevtyRqpkngge.. + n+ +t+t+++++W+ + i+gY+v yR +++g + + KIAA1568 640 LVRLHNP--VVLTPTTVQVTWTVDRQPQFIQGYRVMYR-QTSGLQat 683 ..wkeltvpgttt.sytltgLkPgteYtvrVqAvnggG.GpeS<-* ++w++l+ + +t +s++l +Lk g++Y+++V+ + ++ +G+ S KIAA1568 684 ssWQNLDAKVPTErSAVLVNLKKGVTYEIKVRPYFNEFqGMDS 726 PF00041.11.fs: domain 2 of 3, from 650 to 715: score 27.2, E = 3.4e-07 *->tstsltlsWspPtgngpitgYevtyRqpkngge....wkeltvpgtt t+t+++++W+ + i+gY+v yR +++g + +++w++l+ + +t KIAA1568 650 TPTTVQVTWTVDRQPQFIQGYRVMYR-QTSGLQatssWQNLDAKVPT 695 t.sytltgLkPgteYtvrVq<-* +s++l +Lk g++Y+++V+ KIAA1568 696 ErSAVLVNLKKGVTYEIKVR 715 PF00041.11.ls: domain 3 of 3, from 738 to 828: score 61.7, E = 2.1e-15 *->PsaP.tnltvtdv...tstsltlsWspPt...gngpitgYevtyRqp PsaP++ +tv v++ +sts+++sW+pP++++ ng i+ Y++ + + KIAA1568 738 PSAPpQSVTVLTVgsyNSTSISVSWDPPPpdhQNGIIQEYKI-W-CL 782 kngge.wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* n+ ++tv+ +s+++ gL Pg +Y v V+A + +G G S KIAA1568 783 GNETRfHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGvGVKS 828 PF00041.11.fs: domain 3 of 3, from 738 to 828: score 59.7, E = 1.6e-16 *->PsaP.tnltvtdv...tstsltlsWspPt...gngpitgYevtyRqp PsaP++ +tv v++ +sts+++sW+pP++++ ng i+ Y++ + + KIAA1568 738 PSAPpQSVTVLTVgsyNSTSISVSWDPPPpdhQNGIIQEYKI-W-CL 782 kngge.wkeltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* n+ ++tv+ +s+++ gL Pg +Y v V+A + +G G S KIAA1568 783 GNETRfHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGvGVKS 828 //