hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/smart.HMMs.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-06331746/chunk_1/iprscan-20080502-06331746.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1568 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SM00409 271.8 5.2e-77 5 SM00408 258.4 5.6e-73 5 SM00060 140.6 1.6e-37 3 SM00406 55.4 7.2e-12 3 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SM00409 1/5 39 131 .. 1 58 [] 41.4 1.2e-07 SM00408 1/5 45 119 .. 1 56 [] 46.3 4e-09 SM00409 2/5 141 224 .. 1 58 [] 60.6 2e-13 SM00408 2/5 147 212 .. 1 56 [] 46.4 3.7e-09 SM00409 3/5 233 313 .. 1 58 [] 51.0 1.5e-10 SM00408 3/5 239 302 .. 1 56 [] 52.6 5.2e-11 SM00406 1/3 243 297 .. 1 76 [] 5.8 0.76 SM00409 4/5 322 411 .. 1 58 [] 61.2 1.3e-13 SM00408 4/5 328 400 .. 1 56 [] 54.4 1.5e-11 SM00406 2/3 332 395 .. 1 76 [] 21.6 0.02 SM00409 5/5 426 508 .. 1 58 [] 57.6 1.6e-12 SM00408 5/5 432 497 .. 1 56 [] 58.7 7.3e-13 SM00406 3/3 436 492 .. 1 76 [] 28.1 0.0013 SM00060 1/3 524 606 .. 1 69 [] 68.4 9e-16 SM00060 2/3 640 723 .. 1 69 [] 22.7 0.05 SM00060 3/3 738 825 .. 1 69 [] 49.5 4.4e-10 Alignments of top-scoring domains: SM00409: domain 1 of 5, from 39 to 131: score 41.4, E = 1.2e-07 *->pp.vtvkeGesvtLtC.as.....titWy.................. p++v v+ Ge+ tL+C+a++ +++ti Wy+++ + ++++++++++ KIAA1568 39 PSdVIVSKGEPTTLNCkAEgrptpTIEWYkdgervetdkddprshrm 85 .........LtI.nvtpe..DsesgGtYtCaat..sgsasseqgttLtVl ++++ L+I + +++++D+ G Y+C+a++ g+a s ++ L+V KIAA1568 86 llpsgslffLRIvHGRRSkpDE---GSYVCVARnyLGEAVS-RNASLEVA 131 <-* KIAA1568 - - SM00408: domain 1 of 5, from 45 to 119: score 46.3, E = 4e-09 *->leGqsVtLtCpasgdpvpnItWlk.gkplp.............sgst G++ tL+C+a+g+p+p+I W+k+g++++++++++++++ +++ KIAA1568 45 SKGEPTTLNCKAEGRPTPTIEWYKdGERVEtdkddprshrmllPSGS 91 Ltiknvsle.....DsGlYtCvArNsvg<-* L + ++ ++++++D+G Y+CvArN g KIAA1568 92 LFFLRIVHGrrskpDEGSYVCVARNYLG 119 SM00409: domain 2 of 5, from 141 to 224: score 60.6, E = 2e-13 *->pp.vtvkeGesvtLtC.as......titWy................. p +v+v +Ge++ L+C+ + +++ +ti+W++++ + +++ + + ++ KIAA1568 141 PTdVVVAAGEPAILECqPPrghpepTIYWKkdkvriddkeerisirg 187 ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++L I+n +++D+ G YtC+ t+ g+ s ++++LtV+ KIAA1568 188 gkLMIsNTRKSDA---GMYTCVGTnmVGERDS-DPAELTVF 224 SM00408: domain 2 of 5, from 147 to 212: score 46.4, E = 3.7e-09 *->leGqsVtLtCp.asgdpvpnItWlk.gkplp........sgstLtik G++++L+C + +g p+p+I W+k+ ++++++++ + g+ L i+ KIAA1568 147 AAGEPAILECQpPRGHPEPTIYWKKdKVRIDdkeerisiRGGKLMIS 193 nvsleDsGlYtCvArNsvg<-* n +++D+G+YtCv++N vg KIAA1568 194 NTRKSDAGMYTCVGTNMVG 212 SM00409: domain 3 of 5, from 233 to 313: score 51.0, E = 1.5e-10 *->pp.vtvkeGesvtLtC.as.....titWy.................. p +++v e e v+++C++++++ +t++W++++ + ++++ + +++ + KIAA1568 233 PInQVVLEEEAVEFRCqVQgdpqpTVRWKkddadlprgrydikddyt 279 LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* L+I++ D+ GtY C a+++ g+ ++ ++tLtV+ KIAA1568 280 LRIkKTMSTDE---GTYMCIAEnrVGKMEA--SATLTVR 313 SM00408: domain 3 of 5, from 239 to 302: score 52.6, E = 5.2e-11 *->leGqsVtLtCpasgdpvpnItWlk.gkplp.......sgstLtiknv le ++V+++C + gdp p+++W+k++ lp+++ + +++ tL+ik KIAA1568 239 LEEEAVEFRCQVQGDPQPTVRWKKdDADLPrgrydikDDYTLRIKKT 285 sleDsGlYtCvArNsvg<-* D+G+Y C+A+N+vg KIAA1568 286 MSTDEGTYMCIAENRVG 302 SM00406: domain 1 of 3, from 243 to 297: score 5.8, E = 0.76 *->svtLsCkaSgftf.yvsWvrqpPsstgkgkglewlgysykgRvtisk v+ C++ g+ ++v W + +++ +gR+ i+ KIAA1568 243 AVEFRCQVQGDPQpTVRWKKDDADLP-------------RGRYDIKD 276 dtltraskndvsLtisnLrpeDtgtYyCar<-* d +L+i+ + D+gtY C KIAA1568 277 D---------YTLRIKKTMSTDEGTYMCIA 297 SM00409: domain 4 of 5, from 322 to 411: score 61.2, E = 1.3e-13 *->pp.vtvkeGesvtLtC.as.....titWy.................. p+++ v G +vt++C+ ++++ + ++W + ++++ +++++++++ KIAA1568 322 PRdQIVAQGRTVTFPCeTKgnpqpAVFWQkegsqnllfpnqpqqpns 368 .........LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<- + + +++++LtI+n++++D+ G Y C+a + +gs+ + ++L+V+ KIAA1568 369 rcsvsptgdLTItNIQRSDA---GYYICQALtvAGSILA--KAQLEVT 411 * KIAA1568 - - SM00408: domain 4 of 5, from 328 to 400: score 54.4, E = 1.5e-11 *->leGqsVtLtCpasgdpvpnItWlk..gkplp...............s +G++Vt++C+ g+p p + W k++++ l ++++++++++ + + KIAA1568 328 AQGRTVTFPCETKGNPQPAVFWQKegSQNLLfpnqpqqpnsrcsvsP 374 gstLtiknvsleDsGlYtCvArNsvg<-* + Lti+n++++D+G+Y C+A +g KIAA1568 375 TGDLTITNIQRSDAGYYICQALTVAG 400 SM00406: domain 2 of 3, from 332 to 395: score 21.6, E = 0.02 *->svtLsCkaSgftf.yvsWvrqpPsstgkgkglewlgy...sykgRvt +vt +C+++g+ + v+W+++ g++ ++ ++++ +R + KIAA1568 332 TVTFPCETKGNPQpAVFWQKE-------GSQNLLFPNqpqQPNSRCS 371 iskdtltraskndvsLtisnLrpeDtgtYyCar<-* +s Lti+n + +D g+Y+C+ KIAA1568 372 VSPTG---------DLTITNIQRSDAGYYICQA 395 SM00409: domain 5 of 5, from 426 to 508: score 57.6, E = 1.6e-12 *->pp.vtvkeGesvtLtC.as.....titWy.................. p ++t + +++ L+C+a++++ + i+W++ + + ++++++ + + + KIAA1568 426 PAnQTLAVDGTALLKCkATgdplpVISWLkegftfpgrdpratiqeq 472 ..LtI.nvtpeDsesgGtYtCaat..sgsasseqgttLtVl<-* ++L+I+n++ +D+ GtYtC+at++sg++s ++ L V+ KIAA1568 473 gtLQIkNLRISDT---GTYTCVATssSGETSW--SAVLDVT 508 SM00408: domain 5 of 5, from 432 to 497: score 58.7, E = 7.3e-13 *->leGqsVtLtCpasgdpvpnItWlk.gkplp.........sgstLtik ++++ L+C+a+gdp p I+Wlk+g p+++++ + + +tL+ik KIAA1568 432 AVDGTALLKCKATGDPLPVISWLKeGFTFPgrdpratiqEQGTLQIK 478 nvsleDsGlYtCvArNsvg<-* n + +D G+YtCvA++s g KIAA1568 479 NLRISDTGTYTCVATSSSG 497 SM00406: domain 3 of 3, from 436 to 492: score 28.1, E = 0.0013 *->svtLsCkaSgftf.yvsWvrqpPsstgkgkglewlgysykgRvtisk ++ L Cka+g+ ++++sW+++ g + g+ R ti KIAA1568 436 TALLKCKATGDPLpVISWLKE---------GFTFPGR--DPRATIQE 471 dtltraskndvsLtisnLrpeDtgtYyCar<-* + +L+i+nLr++DtgtY+C KIAA1568 472 QG---------TLQIKNLRISDTGTYTCVA 492 SM00060: domain 1 of 3, from 524 to 606: score 68.4, E = 9e-16 *->PgpPsnptelrvtdvtststsdltsvtlsWepP..........ivgY PgpPs ++vtdvt++ svtlsW+p ++ + + +i++ KIAA1568 524 PGPPSK---PQVTDVTKN------SVTLSWQPGtpgtlpasayIIEA 561 r...................ytltgLkPgaepwteYefrVrAvngndaGe +++++++++++ + ++++ yt++gL+P+ t Y f VrA+n +G KIAA1568 562 FsqsvsnswqtvanhvkttlYTVRGLRPN----TIYLFMVRAINP--QGL 605 g<-* + KIAA1568 606 S 606 SM00060: domain 2 of 3, from 640 to 723: score 22.7, E = 0.05 *->PgpPsnptelrvtdvtststsdltsvtlsWepP.....ivgYr.... n ++v t+t +v+++W+ + i gYr+ + KIAA1568 640 LVRLHN---PVVL--TPT------TVQVTWTVDrqpqfIQGYRvmyr 675 .......................ytltgLkPgaepwteYefrVrAvngnd ++++ + ++++++ + +++++++++l +Lk g +Ye++Vr + KIAA1568 676 qtsglqatsswqnldakvptersAVLVNLKKG----VTYEIKVRPYFN-- 719 aGeg<-* +g KIAA1568 720 EFQG 723 SM00060: domain 3 of 3, from 738 to 825: score 49.5, E = 4.4e-10 *->PgpPsnptelrvtdvtststsdltsvtlsWepP........ivgYr. P++P+ + ++v v+s ++ ts+++sW+pP++++ ++ i +Y+ KIAA1568 738 PSAPPQS--VTVLTVGSYNS---TSISVSWDPPppdhqngiIQEYKi 779 .....................ytltgLkPgaepwteYefrVrAvngndaG + +++++ +++++ +++++ gL Pg +Y++ V+A ++ aG KIAA1568 780 wclgnetrfhinktvdaairsVIIGGLFPG----IQYRVEVAASTS--AG 823 eg<-* g KIAA1568 824 VG 825 //