hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-06414090/chunk_1/iprscan-20080502-06414090.nocrc
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Query sequence: KIAA1573
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF08399.1.fs VWA N-terminal                                 151.6    7.2e-47   1
PF08399.1.ls VWA N-terminal                                 152.5    1.1e-42   1
PF02743.8.fs Cache domain                                    47.0    5.7e-13   2
PF02743.8.ls Cache domain                                    46.9    6.3e-11   2
PF00092.18.ls von Willebrand factor type A domain              1.1     0.0027   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF08399.1.ls   1/1       1   115 [.     1   137 []   152.5  1.1e-42
PF08399.1.fs   1/1       1   115 [.     1   137 []   151.6  7.2e-47
PF00092.18.ls   1/1     139   334 ..     1   195 []     1.1   0.0027
PF02743.8.fs   1/2     364   443 ..     1    92 []    39.2  9.8e-11
PF02743.8.ls   1/2     364   443 ..     1    92 []    41.0  3.7e-09
PF02743.8.fs   2/2     683   764 ..     1    82 [.     7.8      0.1

Alignments of top-scoring domains:
PF08399.1.ls: domain 1 of 1, from 1 to 115: score 152.5, E = 1.1e-42
                   *->AEnaALqeahefnedlaannfqYYdAkainepgeiITPapeidgnla
                       +++  +e++++++d++++n+q+++A++++++++          +l+
    KIAA1573     1    -KKI--REKFNRYLDVVNRNKQVVEASYTAHLTS----------PLT 34   

                   elgtkyntkemvLepdanFknlpVNtsvSsVhvPtnvYdrdPevlnalnW
                   +++++++++++++e+d+nF++ +V++++S+++++t+v++r      a+n+
    KIAA1573    35 AIQDCCTIPPSMMEFDGNFNT-NVSRTISCDRLSTTVNSR------AFNP 77   

                   SeaKFLDkVFreNyeeDPtLsWQYFGSstGflRyYPAtkW<-*
                   +++  L++V+++N++++P+++WQYF+S++G+++++PA+k+   
    KIAA1573    78 GRD--LNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKF    115  

PF08399.1.fs: domain 1 of 1, from 1 to 115: score 151.6, E = 7.2e-47
                   *->AEnaALqeahefnedlaannfqYYdAkainepgeiITPapeidgnla
                       +++  +e++++++d++++n+q+++A++++++++          +l+
    KIAA1573     1    -KKI--REKFNRYLDVVNRNKQVVEASYTAHLTS----------PLT 34   

                   elgtkyntkemvLepdanFknlpVNtsvSsVhvPtnvYdrdPevlnalnW
                   +++++++++++++e+d+nF++ +V++++S+++++t+v++r      a+n+
    KIAA1573    35 AIQDCCTIPPSMMEFDGNFNT-NVSRTISCDRLSTTVNSR------AFNP 77   

                   SeaKFLDkVFreNyeeDPtLsWQYFGSstGflRyYPAtkW<-*
                   +++  L++V+++N++++P+++WQYF+S++G+++++PA+k+   
    KIAA1573    78 GRD--LNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKF    115  

PF00092.18.ls: domain 1 of 1, from 139 to 334: score 1.1, E = 0.0027
                   *->DivFllDgSgSigeenlFekvkdFvkklveknldigpdgtrVglvqY
                       iv +lD   S+++ + ++ +kd++  +++       +++ +++++ 
    KIAA1573   139    HIVVILDHGASVTDTQ-LQIAKDAAQVILS----AIDEHDKISVLTV 180  

                   ssdvr.........tefsLndysskddllaavlknlrylgGgTnNtgkAL
                   +++vr+ + ++  +t  s  ++ +k +++  v   ++++   T   + ++
    KIAA1573   181 ADTVRtcsldqcykTFLSPATSETKRKMSTFV-SSVKSSDSPTQ-HAVGF 228  

                   kyalenlfsstMikrnrsagsRp.enapkvlillTDGksndggsve.aaa
                   ++a +++ s+       ++    + n   v+i l+ G  + ++s+e++ a
    KIAA1573   229 QKAFQLIRST-------NNNTKFqANTDMVIIYLSAGITSKDSSEEdKKA 271  

                   alrdkk..........kgvgitvfavGvGgdvdeaeLr.iasepcseghv
                    l+  +++++  +++ + +  ++   Gv+g    a+Lr++a   + ++  
    KIAA1573   272 TLQVINeensflnnsvMILTYALMNDGVTGLKELAFLRdLA---EQNSGK 318  

                   fyvedfdalwlqlqdiqeql<-*
                   + v+d  a  l+   i   +   
    KIAA1573   319 YGVPDRTA--LP--VIKGSM    334  

PF02743.8.fs: domain 1 of 2, from 364 to 443: score 39.2, E = 9.8e-11
                   *->wTePYvdaastgdmViTvsvPvydrtneqrnktndngdllGVvgiDv
                      ++ P+ d+  +++++ Tvs+P y             + llG vg+Dv
    KIAA1573   364    FSLPFSDEM-GDGLIMTVSKPCYF-----------GNLLLGIVGVDV 398  

                   pledLlkltksiklGktGYaFivdnnGkvlaHPnlrpvtkllkdw<-*
                   +l  +l+++  ++   + Y F++d +G++l HP l  ++ l++ +   
    KIAA1573   399 NLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPP    443  

PF02743.8.ls: domain 1 of 2, from 364 to 443: score 41.0, E = 3.7e-09
                   *->wTePYvdaastgdmViTvsvPvydrtneqrnktndngdllGVvgiDv
                      ++ P+ d+  +++++ Tvs+P y             + llG vg+Dv
    KIAA1573   364    FSLPFSDEM-GDGLIMTVSKPCYF-----------GNLLLGIVGVDV 398  

                   pledLlkltksiklGktGYaFivdnnGkvlaHPnlrpvtkllkdw<-*
                   +l  +l+++  ++   + Y F++d +G++l HP l  ++ l++ +   
    KIAA1573   399 NLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPP    443  

PF02743.8.fs: domain 2 of 2, from 683 to 764: score 7.8, E = 0.1
                   *->wTePYvdaastgdmViTvsvPvydrtneqrnktn.dngdllGVvgiD
                      +T PY d   + + V+T+s  +        ++t    g    V+giD
    KIAA1573   683    LTGPYLDVG-GAGYVVTISHTIHS------SSTQlSSGHTVAVMGID 722  

                   vpledLlkltksi......klGktGYaFivdnnGkvlaHPnl<-*
                    +l  + k + ++ +  +++ G + ++Fi+   G+++aHP l   
    KIAA1573   723 FTLRYFYKVLMDLlpvcnqDGGNKIRCFIMEDRGYLVAHPTL    764  

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