hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-08375097/chunk_1/iprscan-20080502-08375097.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1642 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00435.11.fs Spectrin repeat 869.5 1.5e-258 18 PF00435.11.ls Spectrin repeat 849.3 1.8e-252 15 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00435.11.fs 2/18 44 148 .. 1 111 [] 101.6 1e-29 PF00435.11.ls 1/15 44 148 .. 1 111 [] 103.5 5.7e-28 PF00435.11.ls 2/15 150 257 .. 1 111 [] 65.5 1.6e-16 PF00435.11.fs 3/18 150 257 .. 1 111 [] 63.5 2.2e-18 PF00435.11.ls 3/15 259 386 .. 1 111 [] 17.1 0.0016 PF00435.11.fs 6/18 388 494 .. 1 111 [] 38.5 6.2e-11 PF00435.11.ls 4/15 388 494 .. 1 111 [] 40.4 5.7e-09 PF00435.11.ls 5/15 496 600 .. 1 111 [] 83.2 7.4e-22 PF00435.11.fs 7/18 496 600 .. 1 111 [] 81.3 1.2e-23 PF00435.11.fs 9/18 703 812 .. 1 111 [] 45.7 4.5e-13 PF00435.11.ls 6/15 703 812 .. 1 111 [] 47.6 3.8e-11 PF00435.11.ls 7/15 814 918 .. 1 111 [] 6.9 0.011 PF00435.11.ls 8/15 920 1023 .. 1 111 [] 68.1 2.6e-17 PF00435.11.fs 11/18 920 1023 .. 1 111 [] 66.2 3.6e-19 PF00435.11.ls 9/15 1025 1128 .. 1 111 [] 31.1 3.6e-06 PF00435.11.fs 12/18 1025 1128 .. 1 111 [] 29.2 3.7e-08 PF00435.11.ls 10/15 1130 1234 .. 1 111 [] 81.4 2.7e-21 PF00435.11.fs 13/18 1130 1234 .. 1 111 [] 79.4 4.1e-23 PF00435.11.ls 11/15 1236 1340 .. 1 111 [] 89.8 7.9e-24 PF00435.11.fs 14/18 1236 1340 .. 1 111 [] 87.8 1.3e-25 PF00435.11.ls 12/15 1342 1447 .. 1 111 [] 71.9 1.9e-18 PF00435.11.fs 15/18 1342 1447 .. 1 111 [] 70.0 2.7e-20 PF00435.11.ls 13/15 1449 1555 .. 1 111 [] 50.6 4.8e-12 PF00435.11.fs 16/18 1449 1555 .. 1 111 [] 48.7 5.8e-14 PF00435.11.fs 17/18 1557 1661 .. 1 111 [] 68.0 1e-19 PF00435.11.ls 14/15 1557 1661 .. 1 111 [] 70.0 7.3e-18 PF00435.11.fs 18/18 1663 1722 .. 1 63 [. 47.2 1.6e-13 PF00435.11.ls 15/15 1663 1765 .. 1 111 [] 22.3 0.00061 Alignments of top-scoring domains: PF00435.11.fs: domain 2 of 18, from 44 to 148: score 101.6, E = 1e-29 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ll+q+F ++++ esW++e +l+s++++ g l +v+a +k kH+ KIAA1642 44 LLAQRFDHKVAMRESWLNENQRLVSQDNF-GYELPAVEAAMK--KHE 87 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq a+ea++aa+++rv+ + ela++L ++eg+y+ ++ ++++ + ++W+ KIAA1642 88 AIEADIAAYEERVQGVA--ELAQAL-AAEGYYDIRRVAAQRDSVLRQWAL 134 LlelaaeRkqkLee<-* L l+ +R+ +Le+ KIAA1642 135 LTGLVGARRTRLEQ 148 PF00435.11.ls: domain 1 of 15, from 44 to 148: score 103.5, E = 5.7e-28 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ll+q+F ++++ esW++e +l+s++++ g l +v+a +k kH+ KIAA1642 44 LLAQRFDHKVAMRESWLNENQRLVSQDNF-GYELPAVEAAMK--KHE 87 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq a+ea++aa+++rv+ + ela++L ++eg+y+ ++ ++++ + ++W+ KIAA1642 88 AIEADIAAYEERVQGVA--ELAQAL-AAEGYYDIRRVAAQRDSVLRQWAL 134 LlelaaeRkqkLee<-* L l+ +R+ +Le+ KIAA1642 135 LTGLVGARRTRLEQ 148 PF00435.11.ls: domain 2 of 15, from 150 to 257: score 65.5, E = 1.6e-16 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l lq+ ++++ + W+ee+ a+L s + g++l e+ Ll+ kH KIAA1642 150 LALQKVFQEMVYMVDWMEEMQAQLLSREC-GQHLVEADDLLQ--KHG 193 aleaelaahqdrvealninelaekLiideghyas...eeiqerleeLner +le ++aa+ +rvealn + a ++ + ++y++ +++ i r+++++ + KIAA1642 194 LLEGDIAAQSERVEALN--AAALRF-SQLQGYQPcdpQVICNRVNHVHGC 240 WeqLlelaaeRkqkLee<-* ++L+e+aa+R+++Le+ KIAA1642 241 LAELQEQAARRRAELEA 257 PF00435.11.fs: domain 3 of 18, from 150 to 257: score 63.5, E = 2.2e-18 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l lq+ ++++ + W+ee+ a+L s + g++l e+ Ll+ kH KIAA1642 150 LALQKVFQEMVYMVDWMEEMQAQLLSREC-GQHLVEADDLLQ--KHG 193 aleaelaahqdrvealninelaekLiideghyas...eeiqerleeLner +le ++aa+ +rvealn + a ++ + ++y++ +++ i r+++++ + KIAA1642 194 LLEGDIAAQSERVEALN--AAALRF-SQLQGYQPcdpQVICNRVNHVHGC 240 WeqLlelaaeRkqkLee<-* ++L+e+aa+R+++Le+ KIAA1642 241 LAELQEQAARRRAELEA 257 PF00435.11.ls: domain 3 of 15, from 259 to 386: score 17.1, E = 0.0016 *->lllqqFqrdaddlesWieekealLssedy.................e l+ ++++++++esW ++ke+lL + ++++ + + ++ ++ KIAA1642 259 RSLWALLQELEEAESWARDKERLL---EAaggggaagaagaagtagG 302 gkdleevqaLlkqlkHkaleaelaahqdrvealninelaekLiideghya ++dl+++ Ll +Hk l+ el +++ +++ +e+L++++g KIAA1642 303 AHDLSSTARLLA--QHKILQGELGGRRALLQQAL--RCGEELVAAGGAVG 348 s.......eeiqerleeLnerWeqLlelaaeRkqkLee<-* ++ ++ + + er + ++rW++L+e+aa+R+++L+e KIAA1642 349 PgadtvhlVGLAERAASARRRWQRLEEAAARRERRLQE 386 PF00435.11.fs: domain 6 of 18, from 388 to 494: score 38.5, E = 6.2e-11 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l+qF d+d l+ W++++ +l+++ d+ g+d+++ + L + +H+ KIAA1642 388 RALHQFGADLDGLLDWLRDAYRLAAAGDF-GHDEASSRRLAR--QHR 431 aleaelaahqdrvealninelaekLiideghyas....eeiqerleeLne al e++ah++ v l ++L++ +g +++ ++q r+ e ++ KIAA1642 432 ALTGEVEAHRGPVSGLR-----RQLATLGGASGAgplvVALQVRVVEAEQ 476 rWeqLlelaaeRkqkLee<-* +++++ e aa R+q+L++ KIAA1642 477 LFAEVTEVAALRRQWLRD 494 PF00435.11.ls: domain 4 of 15, from 388 to 494: score 40.4, E = 5.7e-09 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l+qF d+d l+ W++++ +l+++ d+ g+d+++ + L + +H+ KIAA1642 388 RALHQFGADLDGLLDWLRDAYRLAAAGDF-GHDEASSRRLAR--QHR 431 aleaelaahqdrvealninelaekLiideghyas....eeiqerleeLne al e++ah++ v l ++L++ +g +++ ++q r+ e ++ KIAA1642 432 ALTGEVEAHRGPVSGLR-----RQLATLGGASGAgplvVALQVRVVEAEQ 476 rWeqLlelaaeRkqkLee<-* +++++ e aa R+q+L++ KIAA1642 477 LFAEVTEVAALRRQWLRD 494 PF00435.11.ls: domain 5 of 15, from 496 to 600: score 83.2, E = 7.4e-22 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l ++++ ++ e+Wi eke++L s+ + + +l++v++ ++ +++ KIAA1642 496 LAVYRMFGEVHACELWIGEKEQWLLSMRV-PDSLDDVEVVQH--RFE 539 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq l e++ + +rv ++n ++ ++L +++gh++s+e+++ +++Ln+rW + KIAA1642 540 SLDQEMNSLMGRVLDVN--HTVQEL-VEGGHPSSDEVRSCQDHLNSRWNR 586 LlelaaeRkqkLee<-* + el+++Rk++ + KIAA1642 587 IVELVEQRKEEMSA 600 PF00435.11.fs: domain 7 of 18, from 496 to 600: score 81.3, E = 1.2e-23 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l ++++ ++ e+Wi eke++L s+ + + +l++v++ ++ +++ KIAA1642 496 LAVYRMFGEVHACELWIGEKEQWLLSMRV-PDSLDDVEVVQH--RFE 539 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq l e++ + +rv ++n ++ ++L +++gh++s+e+++ +++Ln+rW + KIAA1642 540 SLDQEMNSLMGRVLDVN--HTVQEL-VEGGHPSSDEVRSCQDHLNSRWNR 586 LlelaaeRkqkLee<-* + el+++Rk++ + KIAA1642 587 IVELVEQRKEEMSA 600 PF00435.11.fs: domain 9 of 18, from 703 to 812: score 45.7, E = 4.5e-13 *->lllqqFqrdaddlesWieekealL.ssedyegkdleevqaLlkqlkH +lq+F++d+d ++ W+ + + ++ se +++lee+ aLl +H KIAA1642 703 GRLQRFLHDLDAFLDWLVRAQEAAgGSEGPLPNSLEEADALLA--RH 747 kaleaelaahqdrvealninelaekLiideghyas...eeiqerleeLne al++e++++++ + + e+L +++ + + +++ ++ e+l +L+ KIAA1642 748 AALKEEVDQREEDYARIV--AASEAL-LAADGAELgpgLALDEWLPHLEL 794 rWeqLlelaaeRkqkLee<-* W +Ll l+++R+++L + KIAA1642 795 GWHKLLGLWEARREALVQ 812 PF00435.11.ls: domain 6 of 15, from 703 to 812: score 47.6, E = 3.8e-11 *->lllqqFqrdaddlesWieekealL.ssedyegkdleevqaLlkqlkH +lq+F++d+d ++ W+ + + ++ se +++lee+ aLl +H KIAA1642 703 GRLQRFLHDLDAFLDWLVRAQEAAgGSEGPLPNSLEEADALLA--RH 747 kaleaelaahqdrvealninelaekLiideghyas...eeiqerleeLne al++e++++++ + + e+L +++ + + +++ ++ e+l +L+ KIAA1642 748 AALKEEVDQREEDYARIV--AASEAL-LAADGAELgpgLALDEWLPHLEL 794 rWeqLlelaaeRkqkLee<-* W +Ll l+++R+++L + KIAA1642 795 GWHKLLGLWEARREALVQ 812 PF00435.11.ls: domain 7 of 15, from 814 to 918: score 6.9, E = 0.011 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk + +q+F+rd+++++ ++ +e Ls ++ + ++e+v++ lk +H+ KIAA1642 814 HIYQLFLRDLRQALVVLRNQEMALSGAEL-PGTVESVEEALK--QHR 857 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq ++ ++ q +++ + ae L + +g e+ qe + L e+ ++ KIAA1642 858 DFLTTMELSQQKMQVAV--QAAEGL-LRQGNIYGEQAQEAVTRLLEKNQE 904 LlelaaeRkqkLee<-* + +a+++ qkL++ KIAA1642 905 NQLRAQQWMQKLHD 918 PF00435.11.ls: domain 8 of 15, from 920 to 1023: score 68.1, E = 2.6e-17 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkql.kH l+lq F+rd+ +l+ Wi ek+ ++ g +++ + +++ + +H KIAA1642 920 LELQHFLRDCHELDGWIHEKMLMA---RD-GTREDNHKLHKR-WlRH 961 kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe +a++aela++++++e+++ ++++L ++e+++ + ++++l e++++W+ KIAA1642 962 QAFMAELAQNKEWLEKIE--REGQQL-MQEKPELAASVRKKLGEIRQCWA 1008 qLlelaaeRkqkLee<-* +L+ ++++ ++L e KIAA1642 1009 ELESTTQAKARQLFE 1023 PF00435.11.fs: domain 11 of 18, from 920 to 1023: score 66.2, E = 3.6e-19 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkql.kH l+lq F+rd+ +l+ Wi ek+ ++ g +++ + +++ + +H KIAA1642 920 LELQHFLRDCHELDGWIHEKMLMA---RD-GTREDNHKLHKR-WlRH 961 kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe +a++aela++++++e+++ ++++L ++e+++ + ++++l e++++W+ KIAA1642 962 QAFMAELAQNKEWLEKIE--REGQQL-MQEKPELAASVRKKLGEIRQCWA 1008 qLlelaaeRkqkLee<-* +L+ ++++ ++L e KIAA1642 1009 ELESTTQAKARQLFE 1023 PF00435.11.ls: domain 9 of 15, from 1025 to 1128: score 31.1, E = 3.6e-06 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++ q+ + ++l++ + +e +L++ d g dl++v + lk k++ KIAA1642 1025 SKADQLVQSFAELDKKLLHMESQLQDVDP-GGDLATVNSQLK--KLQ 1068 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +e ++ + + v +l+ ++ ++L ++ + e + er++++ er + KIAA1642 1069 SMESQVEEWYREVGELQ--AQTAAL--PLEPASKELVGERQNAVGERLVR 1114 LlelaaeRkqkLee<-* Lle ++eR++ L++ KIAA1642 1115 LLEPLQERRRLLLA 1128 PF00435.11.fs: domain 12 of 18, from 1025 to 1128: score 29.2, E = 3.7e-08 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++ q+ + ++l++ + +e +L++ d g dl++v + lk k++ KIAA1642 1025 SKADQLVQSFAELDKKLLHMESQLQDVDP-GGDLATVNSQLK--KLQ 1068 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +e ++ + + v +l+ ++ ++L ++ + e + er++++ er + KIAA1642 1069 SMESQVEEWYREVGELQ--AQTAAL--PLEPASKELVGERQNAVGERLVR 1114 LlelaaeRkqkLee<-* Lle ++eR++ L++ KIAA1642 1115 LLEPLQERRRLLLA 1128 PF00435.11.ls: domain 10 of 15, from 1130 to 1234: score 81.4, E = 2.7e-21 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++l+q ++d+dd+++W +e +l++++++ g+ l++vq++ k k + KIAA1642 1130 KELHQVAHDLDDELAWVQERLPLAMQTER-GNGLQAVQQHIK--KNQ 1173 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +l++e++ah +r+e++ e a +L ++ +++e+++ le+L ++W+ KIAA1642 1174 GLRREIQAHGPRLEEVL--ERAGAL-ASLRSPEAEAVRRGLEQLQSAWAG 1220 LlelaaeRkqkLee<-* L+e+a++R+q L + KIAA1642 1221 LREAAERRQQVLDA 1234 PF00435.11.fs: domain 13 of 18, from 1130 to 1234: score 79.4, E = 4.1e-23 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++l+q ++d+dd+++W +e +l++++++ g+ l++vq++ k k + KIAA1642 1130 KELHQVAHDLDDELAWVQERLPLAMQTER-GNGLQAVQQHIK--KNQ 1173 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +l++e++ah +r+e++ e a +L ++ +++e+++ le+L ++W+ KIAA1642 1174 GLRREIQAHGPRLEEVL--ERAGAL-ASLRSPEAEAVRRGLEQLQSAWAG 1220 LlelaaeRkqkLee<-* L+e+a++R+q L + KIAA1642 1221 LREAAERRQQVLDA 1234 PF00435.11.ls: domain 11 of 15, from 1236 to 1340: score 89.8, E = 7.9e-24 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk + +q++ d++++e+W+ e+e l++sed+ gkd++++ +Llk kH KIAA1642 1236 FQVEQYYFDVAEVEAWLGEQELLMMSEDK-GKDEQSTLQLLK--KHL 1279 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +le ++++++ + +l + ++L ++ gh++se+i+ r++++++++ + KIAA1642 1280 QLEQGVENYEESIAQLS--RQCRAL-LEMGHPDSEQISRRQSQVDRLYVA 1326 LlelaaeRkqkLee<-* L+el +eR+ +Le+ KIAA1642 1327 LKELGEERRVALEQ 1340 PF00435.11.fs: domain 14 of 18, from 1236 to 1340: score 87.8, E = 1.3e-25 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk + +q++ d++++e+W+ e+e l++sed+ gkd++++ +Llk kH KIAA1642 1236 FQVEQYYFDVAEVEAWLGEQELLMMSEDK-GKDEQSTLQLLK--KHL 1279 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +le ++++++ + +l + ++L ++ gh++se+i+ r++++++++ + KIAA1642 1280 QLEQGVENYEESIAQLS--RQCRAL-LEMGHPDSEQISRRQSQVDRLYVA 1326 LlelaaeRkqkLee<-* L+el +eR+ +Le+ KIAA1642 1327 LKELGEERRVALEQ 1340 PF00435.11.ls: domain 12 of 15, from 1342 to 1447: score 71.9, E = 1.9e-18 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk + l+q+ r++++le Wi eke ++ s+++ g+d e+v +L++ k+ KIAA1642 1342 YWLYQLSRQVSELEHWIAEKEVVAGSPEL-GQDFEHVSVLQE--KFS 1385 aleaelaa.hqdrvealninelaekLiideghyaseeiqerleeLnerWe ++ e ++r+ a+n ++ ++L i+ gh a+ e++++Lne+W+ KIAA1642 1386 EFASETGMaGRERLAAVN--QMVDEL-IECGHTAAATMAEWKDGLNEAWA 1432 qLlelaaeRkqkLee<-* +Llel+ +R q L + KIAA1642 1433 ELLELMGTRAQLLAA 1447 PF00435.11.fs: domain 15 of 18, from 1342 to 1447: score 70.0, E = 2.7e-20 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk + l+q+ r++++le Wi eke ++ s+++ g+d e+v +L++ k+ KIAA1642 1342 YWLYQLSRQVSELEHWIAEKEVVAGSPEL-GQDFEHVSVLQE--KFS 1385 aleaelaa.hqdrvealninelaekLiideghyaseeiqerleeLnerWe ++ e ++r+ a+n ++ ++L i+ gh a+ e++++Lne+W+ KIAA1642 1386 EFASETGMaGRERLAAVN--QMVDEL-IECGHTAAATMAEWKDGLNEAWA 1432 qLlelaaeRkqkLee<-* +Llel+ +R q L + KIAA1642 1433 ELLELMGTRAQLLAA 1447 PF00435.11.ls: domain 13 of 15, from 1449 to 1555: score 50.6, E = 4.8e-12 *->lllqqFqrdaddlesWieekealL.ssedyegkdleevqaLlkqlkH +l++F++da++l+ ieek++ L+ + ++ ++ ++++ + KIAA1642 1449 RELHKFFSDARELQGQIEEKRRRLpRLTTP-PEPRPSASSMQR--TL 1492 kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe +a+e++l+ + +v++l+ e a++L++ + ++ +e+i +r +e+ + W+ KIAA1642 1493 RAFEHDLQLLVSQVRQLQ--EGAAQLRTVYAGEHAEAIASREQEVLQGWK 1540 qLlelaaeRkqkLee<-* +Ll ++++ + KIAA1642 1541 ELLSACEDARLHVSS 1555 PF00435.11.fs: domain 16 of 18, from 1449 to 1555: score 48.7, E = 5.8e-14 *->lllqqFqrdaddlesWieekealL.ssedyegkdleevqaLlkqlkH +l++F++da++l+ ieek++ L+ + ++ ++ ++++ + KIAA1642 1449 RELHKFFSDARELQGQIEEKRRRLpRLTTP-PEPRPSASSMQR--TL 1492 kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe +a+e++l+ + +v++l+ e a++L++ + ++ +e+i +r +e+ + W+ KIAA1642 1493 RAFEHDLQLLVSQVRQLQ--EGAAQLRTVYAGEHAEAIASREQEVLQGWK 1540 qLlelaaeRkqkLee<-* +Ll ++++ + KIAA1642 1541 ELLSACEDARLHVSS 1555 PF00435.11.fs: domain 17 of 18, from 1557 to 1661: score 68.0, E = 1e-19 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++ +F+++++dl+sW++++ ++ + d+ ++d+++v++L+ H+ KIAA1642 1557 ADALRFHSQVRDLLSWMDGIASQIGAADK-PRDVSSVEVLMN--YHQ 1600 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +l+ el+a+ + + +++ el++ L + ++ ++eiq++l+ L +r e+ KIAA1642 1601 GLKTELEARVPELTTCQ--ELGRSL-LLNKSAMADEIQAQLDKLGTRKEE 1647 LlelaaeRkqkLee<-* + e +++++++L++ KIAA1642 1648 VSEKWDRHWEWLQQ 1661 PF00435.11.ls: domain 14 of 15, from 1557 to 1661: score 70.0, E = 7.3e-18 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk ++ +F+++++dl+sW++++ ++ + d+ ++d+++v++L+ H+ KIAA1642 1557 ADALRFHSQVRDLLSWMDGIASQIGAADK-PRDVSSVEVLMN--YHQ 1600 aleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWeq +l+ el+a+ + + +++ el++ L + ++ ++eiq++l+ L +r e+ KIAA1642 1601 GLKTELEARVPELTTCQ--ELGRSL-LLNKSAMADEIQAQLDKLGTRKEE 1647 LlelaaeRkqkLee<-* + e +++++++L++ KIAA1642 1648 VSEKWDRHWEWLQQ 1661 PF00435.11.fs: domain 18 of 18, from 1663 to 1722: score 47.2, E = 1.6e-13 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l+ +qF+++a +++W++ +e+lL+s ++ g +++ev++L + +H+ KIAA1642 1663 LEVHQFAQEAVVADAWLTAQEPLLQSREL-GSSVDEVEQLIR--RHE 1706 aleaelaahqdrveal<-* a+++ aa+++r+ +l KIAA1642 1707 AFRKAAAAWEERFSSL 1722 PF00435.11.ls: domain 15 of 15, from 1663 to 1765: score 22.3, E = 0.00061 *->lllqqFqrdaddlesWieekealLssedyegkdleevqaLlkqlkHk l+ +qF+++a +++W++ +e+lL+s ++ g +++ev++L + +H+ KIAA1642 1663 LEVHQFAQEAVVADAWLTAQEPLLQSREL-GSSVDEVEQLIR--RHE 1706 aleaelaahqdrvealn.i.nelaekLiideghyaseeiqerleeLnerW a+++ aa+++r+ +l +++ + k ++++ + ++ + + + KIAA1642 1707 AFRKAAAAWEERFSSLRrLtTIEKIKA-EQSKQPPTPLLGRKF------F 1749 eqLlelaaeRkqkLee<-* + elaa L+ KIAA1642 1750 GDPTELAAKAAPLLRP 1765 //