hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-11585656/chunk_1/iprscan-20080502-11585656.nocrc
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Query sequence: KIAA1760
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       213.5    4.5e-61   1
PF00069.15.fs Protein kinase domain                       211.6    1.7e-60   1
PF07714.7.fs Protein tyrosine kinase                      81.7    1.3e-23   1
PF07714.7.ls Protein tyrosine kinase                      77.0    5.4e-20   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1     190   448 ..     1   287 []   211.6  1.7e-60
PF07714.7.fs   1/1     190   404 ..     1   230 [.    81.7  1.3e-23
PF00069.15.ls   1/1     190   448 ..     1   287 []   213.5  4.5e-61
PF07714.7.ls   1/1     190   448 ..     1   272 []    77.0  5.4e-20

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 190 to 448: score 211.6, E = 1.7e-60
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      +++   lG+Gsf tVyk+ +  t  +VA  ++  rk  + ++++   
    KIAA1760   190    LKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKE 236  

                   lsEiqilkrLsHpNIvrlidvfed....kdhlylVlEycegGLrvldLfd
                     E+++lk L+HpNIvr++d++e++ ++k+ + lV+E++  G     L++
    KIAA1760   237 --EAEMLKGLQHPNIVRFYDFWESsakgKRCIVLVTELMTSG----TLKT 280  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   r +++   +++++++++Qil+gl +LH +++ iiHRDLK +NI+
    KIAA1760   281 YLK---RFKVM--KPKVLRSWCRQILKGLLFLHTRtpPIIHRDLKCDNIF 325  

                   ld.nngvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                   + + +g v    Ki+D GlA    +++ s ++++ GTp++mAPE     +
    KIAA1760   326 ITgPTGSV----KIGDLGLAT---LkRASfAKSVIGTPEFMAPEM--YEE 366  

                   gygtkvDvWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefd
                   +y+ +vDv+++G  + e++t + P+s++     +  q++rk+ +++ + +
    KIAA1760   367 HYDESVDVYAFGMCMLEMATSEYPYSEC----QNAAQIYRKVTCGIKPAS 412  

                   spewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<
                   +++ ++             +e k++i  c++k+ ++R+ ++++l H +f 
    KIAA1760   413 FEKVHD-------------PEIKEIIGECICKNKEERYEIKDLLSHAFF  448  

                   -*
                     
    KIAA1760     -    -    

PF07714.7.fs: domain 1 of 1, from 190 to 404: score 81.7, E = 1.3e-23
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                      lk++ +LG+G+F +VykG  +    +t ++VA   L+   + +  e 
    KIAA1760   190    LKFDIELGRGSFKTVYKGLDT----ETWVEVAWCELqDR-KLTKLE- 230  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpg.lyiVtEymegG
                    r+ F +EA+++k l +HpNiVr++ +    +   g+  + +VtE+m  G
    KIAA1760   231 -RQRFKEEAEMLKGL-QHPNIVRFYDFWES-SAK-GKRcIVLVTELMTSG 276  

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLeskn..fvHRDLAARN
                    L+++L++    +  + k L s+++Qi kG+ +L+ + ++++HRDL + N
    KIAA1760   277 TLKTYLKR---FKVMKPKVLRSWCRQILKGLLFLHTRTppIIHRDLKCDN 323  

                   cLVsenl.vVKIsDFGLaRdiynddyYvrkkgggklPv...kWmAPEslk
                   + ++ + + VKI+D GLa +        r++  +k  ++++  mAPE  +
    KIAA1760   324 IFITGPTgSVKIGDLGLATLK-------RASF-AKSVIgtpEFMAPE--M 363  

                   ygk.FtskSDVWSFGVlLWEiftlGeqPFYpgm.sneevlell<-*
                   y +++ +  DV++FG ++ E+ t  e P Y +++  ++++ ++   
    KIAA1760   364 YEEhYDESVDVYAFGMCMLEMAT-SEYP-YSECqNAAQIYRKV    404  

PF00069.15.ls: domain 1 of 1, from 190 to 448: score 213.5, E = 4.5e-61
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      +++   lG+Gsf tVyk+ +  t  +VA  ++  rk  + ++++   
    KIAA1760   190    LKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKE 236  

                   lsEiqilkrLsHpNIvrlidvfed....kdhlylVlEycegGLrvldLfd
                     E+++lk L+HpNIvr++d++e++ ++k+ + lV+E++  G     L++
    KIAA1760   237 --EAEMLKGLQHPNIVRFYDFWESsakgKRCIVLVTELMTSG----TLKT 280  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   r +++   +++++++++Qil+gl +LH +++ iiHRDLK +NI+
    KIAA1760   281 YLK---RFKVM--KPKVLRSWCRQILKGLLFLHTRtpPIIHRDLKCDNIF 325  

                   ld.nngvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                   + + +g v    Ki+D GlA    +++ s ++++ GTp++mAPE     +
    KIAA1760   326 ITgPTGSV----KIGDLGLAT---LkRASfAKSVIGTPEFMAPEM--YEE 366  

                   gygtkvDvWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefd
                   +y+ +vDv+++G  + e++t + P+s++     +  q++rk+ +++ + +
    KIAA1760   367 HYDESVDVYAFGMCMLEMATSEYPYSEC----QNAAQIYRKVTCGIKPAS 412  

                   spewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<
                   +++ ++             +e k++i  c++k+ ++R+ ++++l H +f 
    KIAA1760   413 FEKVHD-------------PEIKEIIGECICKNKEERYEIKDLLSHAFF  448  

                   -*
                     
    KIAA1760     -    -    

PF07714.7.ls: domain 1 of 1, from 190 to 448: score 77.0, E = 5.4e-20
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                      lk++ +LG+G+F +VykG  +    +t ++VA   L+   + +  e 
    KIAA1760   190    LKFDIELGRGSFKTVYKGLDT----ETWVEVAWCELqDR-KLTKLE- 230  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpg.lyiVtEymegG
                    r+ F +EA+++k l +HpNiVr++ +    +   g+  + +VtE+m  G
    KIAA1760   231 -RQRFKEEAEMLKGL-QHPNIVRFYDFWES-SAK-GKRcIVLVTELMTSG 276  

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLeskn..fvHRDLAARN
                    L+++L++    +  + k L s+++Qi kG+ +L+ + ++++HRDL + N
    KIAA1760   277 TLKTYLKR---FKVMKPKVLRSWCRQILKGLLFLHTRTppIIHRDLKCDN 323  

                   cLVsenl.vVKIsDFGLaRdiynddyYvrkkgggklPv...kWmAPEslk
                   + ++ + + VKI+D GLa +        r++  +k  ++++  mAPE  +
    KIAA1760   324 IFITGPTgSVKIGDLGLATLK-------RASF-AKSVIgtpEFMAPE--M 363  

                   ygk.FtskSDVWSFGVlLWEiftlGeqPFYpgm.sneevlellyedGyRL
                   y +++ +  DV++FG ++ E+ t  e P Y +++  ++++ +++      
    KIAA1760   364 YEEhYDESVDVYAFGMCMLEMAT-SEYP-YSECqNAAQIYRKVTCGIKPA 411  

                   prPenCPdelYdlMlqCWaedPedRPtFsel..veeL<-*
                      +   +e+ +++ +C  ++ e+R   ++l ++ ++   
    KIAA1760   412 SFEKVHDPEIKEIIGECICKNKEERYEIKDLlsHAFF    448  

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