hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-12074362/chunk_1/iprscan-20080502-12074362.nocrc
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Query sequence: KIAA1765
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       362.3   7.3e-106   1
PF00069.15.fs Protein kinase domain                       360.4   2.7e-105   1
PF07714.7.fs Protein tyrosine kinase                      80.1    3.8e-23   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1     316   573 ..     1   287 []   360.4 2.7e-105
PF07714.7.fs   1/1     316   464 ..     1   161 [.    80.1  3.8e-23
PF00069.15.ls   1/1     316   573 ..     1   287 []   362.3 7.3e-106

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 316 to 573: score 360.4, E = 2.7e-105
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      ye+++++G G+f++V++++h+ t++ +A+Kii+k++ k k+d+ +  
    KIAA1765   316    YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVD-- 360  

                   lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse
                    sEi i ++LsHpNIv+l++v+e++ ++yl+lEy++gG    dLfd++  
    KIAA1765   361 -SEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG----DLFDAII- 404  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv
                     ++ ++  +e +a  ++  ++++l ++H+++i+HRDLKPeN+L+ +n +
    KIAA1765   405 --ESVKF--PEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNED 450  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                    +++lK+aDFGlAk   +   + + t++GTp Y+APE+l   +gyg +vD
    KIAA1765   451 KSTTLKLADFGLAK---HvVRPiF-TVCGTPTYVAPEILS-EKGYGLEVD 495  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +W++Gvily+ll+G pPF++    ++dq++l+  i  + +ef  p+wd+i
    KIAA1765   496 MWAAGVILYILLCGFPPFRSP---ERDQDELFNIIQLGHFEFLPPYWDNI 542  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                   s           ++akdL++++L +DP+kR+ta+++lqHPw+   
    KIAA1765   543 S-----------DAAKDLVSRLLVVDPKKRYTAHQVLQHPWI    573  

PF07714.7.fs: domain 1 of 1, from 316 to 464: score 80.1, E = 3.8e-23
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie
                       + g+++G G+F +V +++ +    +t++  A K++ + ++  +   
    KIAA1765   316    YETGRVIGDGNFAVVKECRHR----ETRQAYAMKII-D-KSRLKG-- 354  

                   redFlr.EAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                   +ed+  +E+ i  +l +HpNiV+L+ v   + e     +y+++Ey++gGd
    KIAA1765   355 KEDMVDsEILIIQSL-SHPNIVKLHEVYETDME-----IYLILEYVQGGD 398  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                   L d   +     +++ +d   + ++ +k++ + ++k +vHRDL   N LV
    KIAA1765   399 LFDAIIE---SVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLV 445  

                   se....nlvVKIsDFGLaR<-*
                    ++++++ + K +DFGLa+   
    KIAA1765   446 QRnedkSTTLKLADFGLAK    464  

PF00069.15.ls: domain 1 of 1, from 316 to 573: score 362.3, E = 7.3e-106
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      ye+++++G G+f++V++++h+ t++ +A+Kii+k++ k k+d+ +  
    KIAA1765   316    YETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVD-- 360  

                   lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse
                    sEi i ++LsHpNIv+l++v+e++ ++yl+lEy++gG    dLfd++  
    KIAA1765   361 -SEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG----DLFDAII- 404  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv
                     ++ ++  +e +a  ++  ++++l ++H+++i+HRDLKPeN+L+ +n +
    KIAA1765   405 --ESVKF--PEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNED 450  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                    +++lK+aDFGlAk   +   + + t++GTp Y+APE+l   +gyg +vD
    KIAA1765   451 KSTTLKLADFGLAK---HvVRPiF-TVCGTPTYVAPEILS-EKGYGLEVD 495  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   +W++Gvily+ll+G pPF++    ++dq++l+  i  + +ef  p+wd+i
    KIAA1765   496 MWAAGVILYILLCGFPPFRSP---ERDQDELFNIIQLGHFEFLPPYWDNI 542  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                   s           ++akdL++++L +DP+kR+ta+++lqHPw+   
    KIAA1765   543 S-----------DAAKDLVSRLLVVDPKKRYTAHQVLQHPWI    573  

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