hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-12522152/chunk_1/iprscan-20080502-12522152.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1790 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00069.15.fs Protein kinase domain 140.4 8.9e-40 1 PF00069.15.ls Protein kinase domain 142.3 1.2e-39 1 PF07714.7.fs Protein tyrosine kinase 84.6 1.9e-24 1 PF07714.7.ls Protein tyrosine kinase 78.8 1.6e-20 1 PF08477.3.ls Miro-like protein 11.8 0.00036 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF08477.3.ls 1/1 1 114 [. 1 139 [] 11.8 0.00036 PF07714.7.ls 1/1 587 874 .. 1 272 [] 78.8 1.6e-20 PF00069.15.fs 1/1 596 874 .. 1 287 [] 140.4 8.9e-40 PF00069.15.ls 1/1 596 874 .. 1 287 [] 142.3 1.2e-39 PF07714.7.fs 1/1 650 874 .. 40 272 .] 84.6 1.9e-24 Alignments of top-scoring domains: PF08477.3.ls: domain 1 of 1, from 1 to 114: score 11.8, E = 0.00036 *->kvvViGdkgvGKSSllqallgeefppniPrvLpkkklpreiqgstya ++ GKS+ll+ l ++ p + + ++++ KIAA1790 1 -------PRQGKSTLLEILQTGRAP----------QVVHGEATIRTT 30 vdtlevdgdtklenvrlkefllilwDtggreelkfehepiAymktaDavl + +l+ + + ++ +++wD+gg +++ ++ + +++ ++ KIAA1790 31 KWELQRPAGSRA---KVESVEFNVWDIGGPASMATVNQCF--FTDKALYV 75 lvyDlsdpeSfervsslikwlpnlrklgkkaiPvilvgnKlD<-* +v l +e e v++l wl n++ ++ + v++vg++lD KIAA1790 76 VVWNLALGE--EAVANLQFWLLNIEAKAPN-AVVLVVGTHLD 114 PF07714.7.ls: domain 1 of 1, from 587 to 874: score 78.8, E = 1.6e-20 *->lklgkk.........LGeGaFGeV.ykGtlkgsgdgteikVAVKtLk l+ k ++++++++ LG+G G+V y++++ +++VAVK KIAA1790 587 LENSKLehsedegsvLGQGGSGTViYRARYQ------GQPVAVKRFH 627 ....................eigaseeeieredFlrEAsiMkklGdHpNi ++ ++ + + ++ ++ + + ++ +F +EAs++ l +Hp i KIAA1790 628 ikkfknfanvpadtmlrhlrA-TDAMKN--FSEFRQEASMLHAL-QHPCI 673 VrLlGvctkegePggpglyiVtEymegGdLldfLrkhr...egrpLtlkd V L+G+ ++ P l+ +E++++ +L + L ++ ++++ pL KIAA1790 674 VALIGISIH---P----LCFALELAPLSSLNTVLSENArdsSFIPLGHML 716 LlsfalQiAkGMeYLesknfvHRDLAARNcLVse....nl.vVKIsDFGL ++a+QiA+G++YL+ kn++ DL N+LV + + +++ +K sD G KIAA1790 717 TQKIAYQIASGLAYLHKKNIIFCDLKSDNILVWSldvkEHiNIKLSDYGI 766 aRdiynddyYvrkkgggklPvkWmAPEslkygk.FtskSDVWSFGVlLWE +R+ ++++ + g APE ++ ++ + +k D S+G +L+E KIAA1790 767 SRQSFHEGAL-GVEG----TPGYQAPE-IRPRIvYDEKVDMFSYGMVLYE 810 iftlGeqPFYpgmsneevlellyedGyR..LprPenCP.delYdlMlqCW +++ G+ P g ++ ++l +G R+ L +Pe l lM++CW KIAA1790 811 LLS-GQRP-ALGHHQLQIAKKL-SKGIRpvLGQPEEVQfRRLQALMMECW 857 aedPedRPtFselveeL<-* + +Pe+RP +v+++ KIAA1790 858 DTKPEKRPLALSVVSQM 874 PF00069.15.fs: domain 1 of 1, from 596 to 874: score 140.4, E = 8.9e-40 *->yelleklGsGsfGtV.ykakhkgtgkiVAvKiikkrkekskkdktar +++lG+G++GtV y+a+ +g + VAvK++ +k k KIAA1790 596 EDEGSVLGQGGSGTViYRARYQGQP--VAVKRFHIKKFKNFA----- 635 rl.......................sEiqilkrLsHpNIvrlidvfedkd + + ++ ++ + ++ ++ ++ + E+++l+ L+Hp+Iv li++ + KIAA1790 636 -NvpadtmlrhlratdamknfsefrQEASMLHALQHPCIVALIGISIHP- 683 hlylVlEycegGLrvldLfdylse...trrkgpllfsedeakkialQilr l++ lE+++ +L ++lse+ ++++ pl +kia+Qi++ KIAA1790 684 -LCFALELAPLS----SLNTVLSEnarDSSFIPL--GHMLTQKIAYQIAS 726 gleYLHsngiiHRDLKPeNILldnngvvda..flKiaDFGlAkklst.ss gl+YLH+++ii +DLK++NIL+ +v+++ +K++D G+++ + KIAA1790 727 GLAYLHKKNIIFCDLKSDNILVW-SLDVKEhiNIKLSDYGISR---QsFH 772 s.lttfvGTpwYmAPEvllggngygtkvDvWSlGvilyelltGkpPFsge +++ ++ GTp+Y APE+ + y+ kvD++S+G +lyell+G+ P g+ KIAA1790 773 EgALGVEGTPGYQAPEIRP-RIVYDEKVDMFSYGMVLYELLSGQRPALGH 821 vqds.ldqlqlirkilgpplefdspewdsisrsefrrlpnlseeakdLik + ++l + i++ ++ + + ++ L+ KIAA1790 822 --HQlQIAKKLSKGIRPVLGQPEEVQF---------------RRLQALMM 854 kcLnkDPskRltaeeilqHPwf<-* c++ +P+kR+ a ++ + KIAA1790 855 ECWDTKPEKRPLALSVVSQ--M 874 PF00069.15.ls: domain 1 of 1, from 596 to 874: score 142.3, E = 1.2e-39 *->yelleklGsGsfGtV.ykakhkgtgkiVAvKiikkrkekskkdktar +++lG+G++GtV y+a+ +g + VAvK++ +k k KIAA1790 596 EDEGSVLGQGGSGTViYRARYQGQP--VAVKRFHIKKFKNFA----- 635 rl.......................sEiqilkrLsHpNIvrlidvfedkd + + ++ ++ + ++ ++ ++ + E+++l+ L+Hp+Iv li++ + KIAA1790 636 -NvpadtmlrhlratdamknfsefrQEASMLHALQHPCIVALIGISIHP- 683 hlylVlEycegGLrvldLfdylse...trrkgpllfsedeakkialQilr l++ lE+++ +L ++lse+ ++++ pl +kia+Qi++ KIAA1790 684 -LCFALELAPLS----SLNTVLSEnarDSSFIPL--GHMLTQKIAYQIAS 726 gleYLHsngiiHRDLKPeNILldnngvvda..flKiaDFGlAkklst.ss gl+YLH+++ii +DLK++NIL+ +v+++ +K++D G+++ + KIAA1790 727 GLAYLHKKNIIFCDLKSDNILVW-SLDVKEhiNIKLSDYGISR---QsFH 772 s.lttfvGTpwYmAPEvllggngygtkvDvWSlGvilyelltGkpPFsge +++ ++ GTp+Y APE+ + y+ kvD++S+G +lyell+G+ P g+ KIAA1790 773 EgALGVEGTPGYQAPEIRP-RIVYDEKVDMFSYGMVLYELLSGQRPALGH 821 vqds.ldqlqlirkilgpplefdspewdsisrsefrrlpnlseeakdLik + ++l + i++ ++ + + ++ L+ KIAA1790 822 --HQlQIAKKLSKGIRPVLGQPEEVQF---------------RRLQALMM 854 kcLnkDPskRltaeeilqHPwf<-* c++ +P+kR+ a ++ + KIAA1790 855 ECWDTKPEKRPLALSVVSQ--M 874 PF07714.7.fs: domain 1 of 1, from 650 to 874: score 84.6, E = 1.9e-24 *->gaseeeieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpgly +a+ +F +EAs++ l +Hp iV L+G+ ++ P l+ KIAA1790 650 DAMKN---FSEFRQEASMLHAL-QHPCIVALIGISIH---P----LC 685 iVtEymegGdLldfLrkhr...egrpLtlkdLlsfalQiAkGMeYLeskn +E++++ +L + L ++ ++++ pL ++a+QiA+G++YL+ kn KIAA1790 686 FALELAPLSSLNTVLSENArdsSFIPLGHMLTQKIAYQIASGLAYLHKKN 735 fvHRDLAARNcLVse....nl.vVKIsDFGLaRdiynddyYvrkkgggkl ++ DL N+LV + + +++ +K sD G +R+ ++++ + g KIAA1790 736 IIFCDLKSDNILVWSldvkEHiNIKLSDYGISRQSFHEGAL-GVEG---- 780 PvkWmAPEslkygk.FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevl APE ++ ++ + +k D S+G +L+E+++ G+ P g ++ KIAA1790 781 TPGYQAPE-IRPRIvYDEKVDMFSYGMVLYELLS-GQRP-ALGHHQLQIA 827 ellyedGyR..LprPenCP.delYdlMlqCWaedPedRPtFselveeL<- ++l +G R+ L +Pe l lM++CW+ +Pe+RP +v+++ KIAA1790 828 KKL-SKGIRpvLGQPEEVQfRRLQALMMECWDTKPEKRPLALSVVSQM 874 * KIAA1790 - - //