hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-15495885/chunk_1/iprscan-20080502-15495885.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1894 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00084.11.ls Sushi domain (SCR repeat) 1274.7 0 26 PF00084.11.fs Sushi domain (SCR repeat) 1227.8 0 26 PF00431.11.fs CUB domain 1072.8 0 11 PF00431.11.ls CUB domain 1060.9 0 10 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00084.11.fs 1/26 4 57 .. 1 65 [] 41.5 1e-09 PF00084.11.ls 1/26 4 57 .. 1 65 [] 43.3 7.4e-10 PF00431.11.ls 1/10 61 166 .. 1 116 [] 115.9 1.1e-31 PF00431.11.fs 1/11 61 166 .. 1 116 [] 114.0 3e-34 PF00084.11.fs 2/26 174 231 .. 1 65 [] 41.2 1.3e-09 PF00084.11.ls 2/26 174 231 .. 1 65 [] 43.0 9.5e-10 PF00431.11.fs 2/11 235 340 .. 1 116 [] 122.6 7.3e-37 PF00431.11.ls 2/10 235 340 .. 1 116 [] 124.5 2.8e-34 PF00084.11.fs 3/26 350 403 .. 1 65 [] 45.8 8.3e-11 PF00084.11.ls 3/26 350 403 .. 1 65 [] 47.6 3.8e-11 PF00431.11.ls 3/10 407 514 .. 1 116 [] 80.2 6e-21 PF00431.11.fs 3/11 407 514 .. 1 116 [] 78.3 2e-23 PF00084.11.ls 4/26 522 577 .. 1 65 [] 49.8 8.6e-12 PF00084.11.fs 4/26 522 577 .. 1 65 [] 48.0 2.4e-11 PF00431.11.fs 4/11 581 686 .. 1 116 [] 93.6 4.7e-28 PF00431.11.ls 4/10 581 686 .. 1 116 [] 95.5 1.5e-25 PF00084.11.ls 5/26 694 750 .. 1 65 [] 38.6 2e-08 PF00084.11.fs 5/26 694 750 .. 1 65 [] 36.7 1.8e-08 PF00431.11.fs 5/11 754 860 .. 1 116 [] 98.4 1.6e-29 PF00431.11.ls 5/10 754 860 .. 1 116 [] 100.3 5.3e-27 PF00084.11.ls 6/26 868 924 .. 1 65 [] 35.2 2.1e-07 PF00084.11.fs 6/26 868 924 .. 1 65 [] 33.3 1.3e-07 PF00431.11.fs 6/11 928 1033 .. 1 116 [] 128.4 1.2e-38 PF00431.11.ls 6/10 928 1033 .. 1 116 [] 130.4 4.8e-36 PF00084.11.ls 7/26 1041 1098 .. 1 65 [] 60.0 7.1e-15 PF00084.11.fs 7/26 1041 1098 .. 1 65 [] 58.2 2.5e-14 PF00431.11.fs 7/11 1102 1140 .. 1 43 [. 29.1 1.6e-08 PF00084.11.fs 8/26 1148 1205 .. 1 65 [] 32.9 1.7e-07 PF00084.11.ls 8/26 1148 1205 .. 1 65 [] 34.8 2.8e-07 PF00431.11.fs 8/11 1209 1314 .. 1 116 [] 116.6 4.7e-35 PF00431.11.ls 7/10 1209 1314 .. 1 116 [] 118.5 1.7e-32 PF00084.11.ls 9/26 1322 1377 .. 1 65 [] 47.4 4.6e-11 PF00084.11.fs 9/26 1322 1377 .. 1 65 [] 45.5 1e-10 PF00431.11.fs 9/11 1381 1486 .. 1 116 [] 118.3 1.5e-35 PF00431.11.ls 8/10 1381 1486 .. 1 116 [] 120.2 5.3e-33 PF00084.11.ls 10/26 1494 1549 .. 1 65 [] 55.9 1.3e-13 PF00084.11.fs 10/26 1494 1549 .. 1 65 [] 54.1 4.4e-13 PF00431.11.fs 10/11 1553 1657 .. 1 116 [] 109.3 8e-33 PF00431.11.ls 9/10 1553 1657 .. 1 116 [] 111.2 2.8e-30 PF00084.11.fs 11/26 1665 1710 .. 1 49 [. 47.8 2.6e-11 PF00084.11.ls 11/26 1665 1722 .. 1 65 [] 49.2 1.2e-11 PF00431.11.ls 10/10 1726 1834 .. 1 116 [] 64.2 3.9e-16 PF00431.11.fs 11/11 1734 1834 .. 9 116 .] 64.4 3.4e-19 PF00084.11.ls 12/26 1839 1897 .. 1 65 [] 40.4 5.8e-09 PF00084.11.fs 12/26 1839 1897 .. 1 65 [] 38.5 6.2e-09 PF00084.11.fs 13/26 1902 1959 .. 1 65 [] 43.6 3.2e-10 PF00084.11.ls 13/26 1902 1959 .. 1 65 [] 45.4 1.8e-10 PF00084.11.fs 14/26 1964 2024 .. 1 65 [] 49.7 8.8e-12 PF00084.11.ls 14/26 1964 2024 .. 1 65 [] 51.5 2.6e-12 PF00084.11.ls 15/26 2029 2082 .. 1 65 [] 53.1 8.4e-13 PF00084.11.fs 15/26 2029 2082 .. 1 65 [] 51.3 2.9e-12 PF00084.11.fs 16/26 2087 2140 .. 1 65 [] 67.2 4.8e-17 PF00084.11.ls 16/26 2087 2140 .. 1 65 [] 69.0 1.4e-17 PF00084.11.fs 17/26 2145 2198 .. 1 65 [] 44.8 1.5e-10 PF00084.11.ls 17/26 2145 2198 .. 1 65 [] 46.6 7.7e-11 PF00084.11.ls 18/26 2203 2260 .. 1 65 [] 60.7 4.5e-15 PF00084.11.fs 18/26 2203 2260 .. 1 65 [] 58.9 1.6e-14 PF00084.11.ls 19/26 2265 2318 .. 1 65 [] 47.7 3.6e-11 PF00084.11.fs 19/26 2265 2318 .. 1 65 [] 45.9 8e-11 PF00084.11.ls 20/26 2326 2379 .. 1 65 [] 59.4 1.1e-14 PF00084.11.fs 20/26 2326 2379 .. 1 65 [] 57.6 3.7e-14 PF00084.11.ls 21/26 2384 2438 .. 1 65 [] 52.2 1.6e-12 PF00084.11.fs 21/26 2384 2438 .. 1 65 [] 50.4 5.6e-12 PF00084.11.ls 22/26 2443 2498 .. 1 65 [] 47.7 3.7e-11 PF00084.11.fs 22/26 2443 2498 .. 1 65 [] 45.9 8.1e-11 PF00084.11.fs 23/26 2503 2556 .. 1 65 [] 54.5 3.3e-13 PF00084.11.ls 23/26 2503 2556 .. 1 65 [] 56.3 9.5e-14 PF00084.11.fs 24/26 2561 2614 .. 1 65 [] 44.0 2.4e-10 PF00084.11.ls 24/26 2561 2614 .. 1 65 [] 45.8 1.3e-10 PF00084.11.ls 25/26 2622 2676 .. 1 65 [] 47.5 4.2e-11 PF00084.11.fs 25/26 2622 2676 .. 1 65 [] 45.7 9.2e-11 PF00084.11.ls 26/26 2681 2736 .. 1 65 [] 46.6 8e-11 PF00084.11.fs 26/26 2681 2736 .. 1 65 [] 44.7 1.6e-10 Alignments of top-scoring domains: PF00084.11.fs: domain 1 of 26, from 4 to 57: score 41.5, E = 1e-09 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+++ G + ++ d+++++C+ G++l+G++si+C+ KIAA1894 4 CG-DPGTPLYGIREGD--GFSN--RDVLRFECQFGFELIGEKSIVCQ 45 edggGgWsppllgelPkC<-* e+ +Ws + P+C KIAA1894 46 EN--NQWSANI----PIC 57 PF00084.11.ls: domain 1 of 26, from 4 to 57: score 43.3, E = 7.4e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+++ G + ++ d+++++C+ G++l+G++si+C+ KIAA1894 4 CG-DPGTPLYGIREGD--GFSN--RDVLRFECQFGFELIGEKSIVCQ 45 edggGgWsppllgelPkC<-* e+ +Ws + P+C KIAA1894 46 EN--NQWSANI----PIC 57 PF00431.11.ls: domain 1 of 10, from 61 to 166: score 115.9, E = 1.1e-31 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF C + +t++ G+ SP+YP+ Y +n +C+WtI pg+r i+L+F KIAA1894 61 CLSN--FTAPMGTVLSPDYPE-GYGNNLNCIWTIISDPGSR-IHLSF 103 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm dFdlE + D++ + DG++ sp+lG f+G + P +S+s+++ KIAA1894 104 NDFDLE-----SQFDFLAVKDGDSPESPILGTFTG-AEVPSHLTSNSHIL 147 tikFvsDssiqkrGFkaty<-* +++F+ D s ++rGF++ty KIAA1894 148 RLEFQADHSMSGRGFNITY 166 PF00431.11.fs: domain 1 of 11, from 61 to 166: score 114.0, E = 3e-34 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF C + +t++ G+ SP+YP+ Y +n +C+WtI pg+r i+L+F KIAA1894 61 CLSN--FTAPMGTVLSPDYPE-GYGNNLNCIWTIISDPGSR-IHLSF 103 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm dFdlE + D++ + DG++ sp+lG f+G + P +S+s+++ KIAA1894 104 NDFDLE-----SQFDFLAVKDGDSPESPILGTFTG-AEVPSHLTSNSHIL 147 tikFvsDssiqkrGFkaty<-* +++F+ D s ++rGF++ty KIAA1894 148 RLEFQADHSMSGRGFNITY 166 PF00084.11.fs: domain 2 of 26, from 174 to 231: score 41.2, E = 1.3e-09 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG.sssitC Cp +p+ + N+r +++ G++++ C+eG+ + ++itC KIAA1894 174 CP-DPGIPINARRFGD--NFQL--GSSISVICEEGFIKTQgTETITC 215 tedgg.GgWsppllgelPkC<-* + +g+ Ws+++ PkC KIAA1894 216 ILMDGkVMWSGLI----PKC 231 PF00084.11.ls: domain 2 of 26, from 174 to 231: score 43.0, E = 9.5e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG.sssitC Cp +p+ + N+r +++ G++++ C+eG+ + ++itC KIAA1894 174 CP-DPGIPINARRFGD--NFQL--GSSISVICEEGFIKTQgTETITC 215 tedgg.GgWsppllgelPkC<-* + +g+ Ws+++ PkC KIAA1894 216 ILMDGkVMWSGLI----PKC 231 PF00431.11.fs: domain 2 of 11, from 235 to 340: score 122.6, E = 7.3e-37 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ + ++sG+I SP++P +Y ++ +C+W I+a+pg++ i++tF KIAA1894 235 CGGH--FSAPSGVILSPGWPG-YYKDSLNCEWVIEAEPGHS-IKITF 277 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + F +E +YD++E+ DG+ spllG++ G + P S sn KIAA1894 278 ERFQTE-----LNYDVLEVHDGPNLLSPLLGSYNG-TQVPQFLFSISNFI 321 tikFvsDssiqkrGFkaty<-* +++F++D+s ++ GFk++y KIAA1894 322 YLLFTTDNSRSNNGFKIHY 340 PF00431.11.ls: domain 2 of 10, from 235 to 340: score 124.5, E = 2.8e-34 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ + ++sG+I SP++P +Y ++ +C+W I+a+pg++ i++tF KIAA1894 235 CGGH--FSAPSGVILSPGWPG-YYKDSLNCEWVIEAEPGHS-IKITF 277 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + F +E +YD++E+ DG+ spllG++ G + P S sn KIAA1894 278 ERFQTE-----LNYDVLEVHDGPNLLSPLLGSYNG-TQVPQFLFSISNFI 321 tikFvsDssiqkrGFkaty<-* +++F++D+s ++ GFk++y KIAA1894 322 YLLFTTDNSRSNNGFKIHY 340 PF00084.11.fs: domain 3 of 26, from 350 to 403: score 45.8, E = 8.3e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ + +Gr + ++ G+tv+++C+ GYrl++++ + C KIAA1894 350 CL-DPGIPVHGRRYGH--DFSI--GSTVSFSCDSGYRLSHEEPLLCE 391 edggGgWsppllgelPkC<-* ++ Ws+pl P+C KIAA1894 392 KN--HWWSHPL----PTC 403 PF00084.11.ls: domain 3 of 26, from 350 to 403: score 47.6, E = 3.8e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ + +Gr + ++ G+tv+++C+ GYrl++++ + C KIAA1894 350 CL-DPGIPVHGRRYGH--DFSI--GSTVSFSCDSGYRLSHEEPLLCE 391 edggGgWsppllgelPkC<-* ++ Ws+pl P+C KIAA1894 392 KN--HWWSHPL----PTC 403 PF00431.11.ls: domain 3 of 10, from 407 to 514: score 80.2, E = 6e-21 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ ++ +sG+I SP+YP+ Yp++ +C+Wt+ ++ g+ ++++F KIAA1894 407 CGGD--VRGPSGTILSPGYPE-FYPNSLNCTWTVDVTHGKG-VQFNF 449 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsn.. + F lEdh Dy+ i + + + + l+r +G s +P++i + + KIAA1894 450 HTFHLEDHH-----DYLLITENGSFT-QPLARLTG-SDLPPTINA-GLyg 491 ..qmtikFvsDssiqkrGFkaty<-* + + ++F+sD si++ GF++t+ KIAA1894 492 nfRAQLRFISDFSISYEGFNITF 514 PF00431.11.fs: domain 3 of 11, from 407 to 514: score 78.3, E = 2e-23 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ ++ +sG+I SP+YP+ Yp++ +C+Wt+ ++ g+ ++++F KIAA1894 407 CGGD--VRGPSGTILSPGYPE-FYPNSLNCTWTVDVTHGKG-VQFNF 449 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsn.. + F lEdh Dy+ i + + + + l+r +G s +P++i + + KIAA1894 450 HTFHLEDHH-----DYLLITENGSFT-QPLARLTG-SDLPPTINA-GLyg 491 ..qmtikFvsDssiqkrGFkaty<-* + + ++F+sD si++ GF++t+ KIAA1894 492 nfRAQLRFISDFSISYEGFNITF 514 PF00084.11.ls: domain 4 of 26, from 522 to 577: score 49.8, E = 8.6e-12 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ ++ G+ + ++ Gdt+t++C GYrl+G s+i C+ KIAA1894 522 CE-DPGIPQYGSRIGF--NFGI--GDTLTFSCSSGYRLEGTSEIICL 563 edgg.GgWsppllgelPkC<-* +gg+ Ws pl P+C KIAA1894 564 -GGGrRVWSAPL----PRC 577 PF00084.11.fs: domain 4 of 26, from 522 to 577: score 48.0, E = 2.4e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ ++ G+ + ++ Gdt+t++C GYrl+G s+i C+ KIAA1894 522 CE-DPGIPQYGSRIGF--NFGI--GDTLTFSCSSGYRLEGTSEIICL 563 edgg.GgWsppllgelPkC<-* +gg+ Ws pl P+C KIAA1894 564 -GGGrRVWSAPL----PRC 577 PF00431.11.fs: domain 4 of 11, from 581 to 686: score 93.6, E = 4.7e-28 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CG +t+ G + SPnYP +Y++n eC++ I+++ g+ i ++ KIAA1894 581 CGAS--ATNNEGILLSPNYPL-NYENNHECIYSIQVQAGKG-INISA 623 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm F l + D+++i+DG +++ llG f+G s + +Stsnq+ KIAA1894 624 RTFHLA------QGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQL 667 tikFvsDssiqkrGFkaty<-* +++F sD + + GF++ y KIAA1894 668 WLEFNSDTEGTDEGFQLVY 686 PF00431.11.ls: domain 4 of 10, from 581 to 686: score 95.5, E = 1.5e-25 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CG +t+ G + SPnYP +Y++n eC++ I+++ g+ i ++ KIAA1894 581 CGAS--ATNNEGILLSPNYPL-NYENNHECIYSIQVQAGKG-INISA 623 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm F l + D+++i+DG +++ llG f+G s + +Stsnq+ KIAA1894 624 RTFHLA------QGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQL 667 tikFvsDssiqkrGFkaty<-* +++F sD + + GF++ y KIAA1894 668 WLEFNSDTEGTDEGFQLVY 686 PF00084.11.ls: domain 5 of 26, from 694 to 750: score 38.6, E = 2e-08 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ +++G+ +s ++ + +t+ y Cn+GY+l Gss ++C+ KIAA1894 694 CE-DPGIPQFGYKISDQGHFAG---STIIYGCNPGYTLHGSSLLKCM 736 edgg.GgWsppllgelPkC<-* +g + W+ pl P+C KIAA1894 737 -TGErRAWDYPL----PSC 750 PF00084.11.fs: domain 5 of 26, from 694 to 750: score 36.7, E = 1.8e-08 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+ +++G+ +s ++ + +t+ y Cn+GY+l Gss ++C+ KIAA1894 694 CE-DPGIPQFGYKISDQGHFAG---STIIYGCNPGYTLHGSSLLKCM 736 edgg.GgWsppllgelPkC<-* +g + W+ pl P+C KIAA1894 737 -TGErRAWDYPL----PSC 750 PF00431.11.fs: domain 5 of 11, from 754 to 860: score 98.4, E = 1.6e-29 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg++ + essG I SP+YP pY +n +C W I++ pg +sL+F KIAA1894 754 CGGRF-KGESSGRILSPGYPF-PYDNNLRCMWMIEVDPGNI-VSLQF 797 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + Fd+E D + ++DG+p++ ll + G s iPe i St n++ KIAA1894 798 LAFDTE-----ASHDILRVWDGPPENDMLLKEISG-SLIPEGIHSTLNIV 841 tikFvsDssiqkrGFkaty<-* ti F +D i+k+GF++ + KIAA1894 842 TIQFDTDFYISKSGFAIQF 860 PF00431.11.ls: domain 5 of 10, from 754 to 860: score 100.3, E = 5.3e-27 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg++ + essG I SP+YP pY +n +C W I++ pg +sL+F KIAA1894 754 CGGRF-KGESSGRILSPGYPF-PYDNNLRCMWMIEVDPGNI-VSLQF 797 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + Fd+E D + ++DG+p++ ll + G s iPe i St n++ KIAA1894 798 LAFDTE-----ASHDILRVWDGPPENDMLLKEISG-SLIPEGIHSTLNIV 841 tikFvsDssiqkrGFkaty<-* ti F +D i+k+GF++ + KIAA1894 842 TIQFDTDFYISKSGFAIQF 860 PF00084.11.ls: domain 6 of 26, from 868 to 924: score 35.2, E = 2.1e-07 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p++++NG+ e Gdtv+++C++GY+l+G+++itC+ KIAA1894 868 CR-DPGVPMNGTRNGD--GREP--GDTVVFQCDPGYELQGEERITCI 909 edgg.GgWsppllgelPkC<-* + W p + P+C KIAA1894 910 QVENrYFWQPSP----PVC 924 PF00084.11.fs: domain 6 of 26, from 868 to 924: score 33.3, E = 1.3e-07 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p++++NG+ e Gdtv+++C++GY+l+G+++itC+ KIAA1894 868 CR-DPGVPMNGTRNGD--GREP--GDTVVFQCDPGYELQGEERITCI 909 edgg.GgWsppllgelPkC<-* + W p + P+C KIAA1894 910 QVENrYFWQPSP----PVC 924 PF00431.11.fs: domain 6 of 11, from 928 to 1033: score 128.4, E = 1.2e-38 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ lt ssG I SPn+P+ pYp + +C WtI+++ y isL+F KIAA1894 928 CGGN--LTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYV-ISLAF 970 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm +F +E +YD++ i+DG++s+spl+G+f +s++Pe i S+sn+m KIAA1894 971 ISFSIE-----PNYDFLYIYDGPDSNSPLIGSFQ-DSKLPERIESSSNTM 1014 tikFvsDssiqkrGFkaty<-* + F sD+s+++ GF++ y KIAA1894 1015 HLAFRSDGSVSYTGFHLEY 1033 PF00431.11.ls: domain 6 of 10, from 928 to 1033: score 130.4, E = 4.8e-36 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ lt ssG I SPn+P+ pYp + +C WtI+++ y isL+F KIAA1894 928 CGGN--LTGSSGFILSPNFPH-PYPHSRDCDWTITVNADYV-ISLAF 970 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm +F +E +YD++ i+DG++s+spl+G+f +s++Pe i S+sn+m KIAA1894 971 ISFSIE-----PNYDFLYIYDGPDSNSPLIGSFQ-DSKLPERIESSSNTM 1014 tikFvsDssiqkrGFkaty<-* + F sD+s+++ GF++ y KIAA1894 1015 HLAFRSDGSVSYTGFHLEY 1033 PF00084.11.ls: domain 7 of 26, from 1041 to 1098: score 60.0, E = 7.1e-15 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p++i+NG+ y+ G+tvty+C+ GY+l+G s++tC+ KIAA1894 1041 CF-DPGNIMNGTRLGM--DYKL--GSTVTYYCDAGYVLQGYSTLTCI 1082 edg.g.GgWsppllgelPkC<-* ++++g+ gW+ +l P+C KIAA1894 1083 MGDdGrPGWNRAL----PSC 1098 PF00084.11.fs: domain 7 of 26, from 1041 to 1098: score 58.2, E = 2.5e-14 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p++i+NG+ y+ G+tvty+C+ GY+l+G s++tC+ KIAA1894 1041 CF-DPGNIMNGTRLGM--DYKL--GSTVTYYCDAGYVLQGYSTLTCI 1082 edg.g.GgWsppllgelPkC<-* ++++g+ gW+ +l P+C KIAA1894 1083 MGDdGrPGWNRAL----PSC 1098 PF00431.11.fs: domain 7 of 11, from 1102 to 1140: score 29.1, E = 1.6e-08 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvi<-* CG + t s G+ SPnYP+ +Y+ +Cv+ I +p+++ + KIAA1894 1102 CGSR--STGSEGTVLSPNYPK-NYSVGHNCVYSIAVPKEFA-V 1140 PF00084.11.fs: domain 8 of 26, from 1148 to 1205: score 32.9, E = 1.7e-07 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ ++P++++Gr + ++ + G++v + Cn+GY l Gs i+C KIAA1894 1148 CS-SVPEPRFGRRIGN--EFAV--GSSVLFDCNPGYILHGSIAIRCE 1189 edg.g.GgWsppllgelPkC<-* + ++ +W+ l P+C KIAA1894 1190 TVPnSlAQWNDSL----PTC 1205 PF00084.11.ls: domain 8 of 26, from 1148 to 1205: score 34.8, E = 2.8e-07 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ ++P++++Gr + ++ + G++v + Cn+GY l Gs i+C KIAA1894 1148 CS-SVPEPRFGRRIGN--EFAV--GSSVLFDCNPGYILHGSIAIRCE 1189 edg.g.GgWsppllgelPkC<-* + ++ +W+ l P+C KIAA1894 1190 TVPnSlAQWNDSL----PTC 1205 PF00431.11.fs: domain 8 of 11, from 1209 to 1314: score 116.6, E = 4.7e-35 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ lt+ G+I SP+YP+ pY +n +CvW I++p+g i+ + KIAA1894 1209 CGGI--LTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAG-IQVQV 1251 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm +F +E + D++ +DG ++++p lG++ G iP Stsn + KIAA1894 1252 VSFATE-----HNWDSLDFYDGGDNNAPRLGSYSG-TTIPHLLNSTSNNL 1295 tikFvsDssiqkrGFkaty<-* ++ F+sD s++++GF++ y KIAA1894 1296 YLNFQSDISVSAAGFHLEY 1314 PF00431.11.ls: domain 7 of 10, from 1209 to 1314: score 118.5, E = 1.7e-32 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ lt+ G+I SP+YP+ pY +n +CvW I++p+g i+ + KIAA1894 1209 CGGI--LTKRKGTILSPGYPE-PYDNNLNCVWKITVPEGAG-IQVQV 1251 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm +F +E + D++ +DG ++++p lG++ G iP Stsn + KIAA1894 1252 VSFATE-----HNWDSLDFYDGGDNNAPRLGSYSG-TTIPHLLNSTSNNL 1295 tikFvsDssiqkrGFkaty<-* ++ F+sD s++++GF++ y KIAA1894 1296 YLNFQSDISVSAAGFHLEY 1314 PF00084.11.ls: domain 9 of 26, from 1322 to 1377: score 47.4, E = 4.6e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp P+ + ++ + + y + Gd+v+++C++GY+l+G+s+itC+ KIAA1894 1322 CP--EPQTPSSGIKIG-DRYMV--GDVVSFQCDQGYSLQGHSHITCM 1363 edggGgWsppllgelPkC<-* ++ + +W+ p+ P+C KIAA1894 1364 PGPVRRWNYPI----PIC 1377 PF00084.11.fs: domain 9 of 26, from 1322 to 1377: score 45.5, E = 1e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp P+ + ++ + + y + Gd+v+++C++GY+l+G+s+itC+ KIAA1894 1322 CP--EPQTPSSGIKIG-DRYMV--GDVVSFQCDQGYSLQGHSHITCM 1363 edggGgWsppllgelPkC<-* ++ + +W+ p+ P+C KIAA1894 1364 PGPVRRWNYPI----PIC 1377 PF00431.11.fs: domain 9 of 11, from 1381 to 1486: score 118.3, E = 1.5e-35 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg + sG+I SP++P +Yp + +C+WtI++p g+ ++L+F KIAA1894 1381 CGGA--MSDFSGVILSPGFPG-NYPSSLDCTWTINLPIGFG-VHLQF 1423 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm F +E + Dy+E+r+G +++s+++Gr G +iP St++ KIAA1894 1424 VNFSTE-----TIHDYLEVRSGSSETSTVIGRLSG-PQIPSSLFSTTHET 1467 tikFvsDssiqkrGFkaty<-* + F+sD+s +k GF++ y KIAA1894 1468 SLYFHSDYSQNKQGFHIVY 1486 PF00431.11.ls: domain 8 of 10, from 1381 to 1486: score 120.2, E = 5.3e-33 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg + sG+I SP++P +Yp + +C+WtI++p g+ ++L+F KIAA1894 1381 CGGA--MSDFSGVILSPGFPG-NYPSSLDCTWTINLPIGFG-VHLQF 1423 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm F +E + Dy+E+r+G +++s+++Gr G +iP St++ KIAA1894 1424 VNFSTE-----TIHDYLEVRSGSSETSTVIGRLSG-PQIPSSLFSTTHET 1467 tikFvsDssiqkrGFkaty<-* + F+sD+s +k GF++ y KIAA1894 1468 SLYFHSDYSQNKQGFHIVY 1486 PF00084.11.ls: domain 10 of 26, from 1494 to 1549: score 55.9, E = 1.3e-13 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp +p++++NG+v+ +++ G+t++++C +GY+l+G+s +tC+ KIAA1894 1494 CP-DPRPFRNGFVIGN--DFTV--GQTISFECFPGYTLIGNSALTCL 1535 edgg.GgWsppllgelPkC<-* ++ ++ +W++pl P+C KIAA1894 1536 HG-VsRNWNHPL----PRC 1549 PF00084.11.fs: domain 10 of 26, from 1494 to 1549: score 54.1, E = 4.4e-13 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp +p++++NG+v+ +++ G+t++++C +GY+l+G+s +tC+ KIAA1894 1494 CP-DPRPFRNGFVIGN--DFTV--GQTISFECFPGYTLIGNSALTCL 1535 edgg.GgWsppllgelPkC<-* ++ ++ +W++pl P+C KIAA1894 1536 HG-VsRNWNHPL----PRC 1549 PF00431.11.fs: domain 10 of 11, from 1553 to 1657: score 109.3, E = 8e-33 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ +t+++G+I+SP+YP+ +Yp+ ++C W++r+ppg i ++F KIAA1894 1553 CGGN--ITAMNGTIYSPGYPD-EYPNFQDCFWLVRVPPGNG-IYINF 1595 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + + +E +YD++ ++DG++ +sp++G f G + e ++Stsnq KIAA1894 1596 TVLQTE-----PIYDFITVWDGPDQNSPQIGQFSG-NTALESVYSTSNQI 1639 tikFvsDssiqkrGFkaty<-* +ikF+s + +++ F ++y KIAA1894 1640 LIKFHS-DFTTSGFFVLSY 1657 PF00431.11.ls: domain 9 of 10, from 1553 to 1657: score 111.2, E = 2.8e-30 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF CGg+ +t+++G+I+SP+YP+ +Yp+ ++C W++r+ppg i ++F KIAA1894 1553 CGGN--ITAMNGTIYSPGYPD-EYPNFQDCFWLVRVPPGNG-IYINF 1595 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + + +E +YD++ ++DG++ +sp++G f G + e ++Stsnq KIAA1894 1596 TVLQTE-----PIYDFITVWDGPDQNSPQIGQFSG-NTALESVYSTSNQI 1639 tikFvsDssiqkrGFkaty<-* +ikF+s + +++ F ++y KIAA1894 1640 LIKFHS-DFTTSGFFVLSY 1657 PF00084.11.fs: domain 11 of 26, from 1665 to 1710: score 47.8, E = 2.6e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C ppP+++N+++ ++ +++e Gd ++y+C++G++lvG++ +tC+ KIAA1894 1665 CQ-PPPPVPNAEILTEDDEFEI--GDIIRYQCLPGFTLVGNAILTCR 1708 ed<-* + KIAA1894 1709 LG 1710 PF00084.11.ls: domain 11 of 26, from 1665 to 1722: score 49.2, E = 1.2e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C ppP+++N+++ ++ +++e Gd ++y+C++G++lvG++ +tC+ KIAA1894 1665 CQ-PPPPVPNAEILTEDDEFEI--GDIIRYQCLPGFTLVGNAILTCR 1708 edgg.GgWsppllgelPkC<-* + + + ++++ P+C KIAA1894 1709 LG-ErLQMDGAP----PVC 1722 PF00431.11.ls: domain 10 of 10, from 1726 to 1834: score 64.2, E = 3.9e-16 *->CGgvldltessGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtF C + + +s+G+I SP+YP+ +Yp+ + C W I++++gy+ i++ KIAA1894 1726 CPANELRLDSTGVILSPGYPD-SYPNLQMCAWSISVEKGYN-ITMFV 1770 qdFdlEdhdgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqm + F +E+ D+++++DG+ sp+l + G++ +i+S+++ + KIAA1894 1771 EFFQTEK-----EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEV 1815 tikFvsDssiqkrGFkaty<-* ++ + D +++k+GF+++y KIAA1894 1816 FLQWSADHGNNKKGFRIRY 1834 PF00431.11.fs: domain 11 of 11, from 1734 to 1834: score 64.4, E = 3.4e-19 *->essGsItSPnYPnrpYppnkeCvWtIrappgyrvisLtFqdFdlEdh +s+G+I SP+YP+ +Yp+ + C W I++++gy+ i++ + F +E+ KIAA1894 1734 DSTGVILSPGYPD-SYPNLQMCAWSISVEKGYN-ITMFVEFFQTEK- 1777 dgaCgYDyVEirDGlpssspllGrfCGgsgiPedirStsnqmtikFvsDs D+++++DG+ sp+l + G++ +i+S+++ +++ + D KIAA1894 1778 ----EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADH 1823 siqkrGFkaty<-* +++k+GF+++y KIAA1894 1824 GNNKKGFRIRY 1834 PF00084.11.ls: domain 12 of 26, from 1839 to 1897: score 40.4, E = 5.8e-09 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ p +++G+++s+ t + +++v+ C+ G+rlvG ss++C+ KIAA1894 1839 CS-TPESPPHGYIISQ-TGGQL--NSVVRWACDRGFRLVGKSSAVCR 1881 edg.g.GgWsppllgelPkC<-* + + g W+ p P C KIAA1894 1882 KSSyGyHAWDAPV----PAC 1897 PF00084.11.fs: domain 12 of 26, from 1839 to 1897: score 38.5, E = 6.2e-09 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ p +++G+++s+ t + +++v+ C+ G+rlvG ss++C+ KIAA1894 1839 CS-TPESPPHGYIISQ-TGGQL--NSVVRWACDRGFRLVGKSSAVCR 1881 edg.g.GgWsppllgelPkC<-* + + g W+ p P C KIAA1894 1882 KSSyGyHAWDAPV----PAC 1897 PF00084.11.fs: domain 13 of 26, from 1902 to 1959: score 43.6, E = 3.2e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG..sssit C+ p + NG + ++ y + G+ vty+Cn+GYrl+ ++ ++++ KIAA1894 1902 CG-IPKAPTNGGILTT--DYLV--GTRVTYFCNDGYRLSSkeLTTAV 1943 CtedggGgWsppllgelPkC<-* C+ d G+Ws+ + + P+C KIAA1894 1944 CQSD--GTWSNHN--KTPRC 1959 PF00084.11.ls: domain 13 of 26, from 1902 to 1959: score 45.4, E = 1.8e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG..sssit C+ p + NG + ++ y + G+ vty+Cn+GYrl+ ++ ++++ KIAA1894 1902 CG-IPKAPTNGGILTT--DYLV--GTRVTYFCNDGYRLSSkeLTTAV 1943 CtedggGgWsppllgelPkC<-* C+ d G+Ws+ + + P+C KIAA1894 1944 CQSD--GTWSNHN--KTPRC 1959 PF00084.11.fs: domain 14 of 26, from 1964 to 2024: score 49.7, E = 8.8e-12 *->Cp.lppPdieNGrvsss.kttyeypvGdtvtytCneGYrlvGsssit Cp++++ +e+Gr++ ++ yey +++v+++C++GY+ G++si KIAA1894 1964 CPsINSFILEHGRWRIVnGSHYEY--KTKVVFSCDPGYHGLGPASIE 2008 CtedggGgWsppllgelPkC<-* C+++ G+Ws ++ e P C KIAA1894 2009 CLPN--GTWSWRN--ERPYC 2024 PF00084.11.ls: domain 14 of 26, from 1964 to 2024: score 51.5, E = 2.6e-12 *->Cp.lppPdieNGrvsss.kttyeypvGdtvtytCneGYrlvGsssit Cp++++ +e+Gr++ ++ yey +++v+++C++GY+ G++si KIAA1894 1964 CPsINSFILEHGRWRIVnGSHYEY--KTKVVFSCDPGYHGLGPASIE 2008 CtedggGgWsppllgelPkC<-* C+++ G+Ws ++ e P C KIAA1894 2009 CLPN--GTWSWRN--ERPYC 2024 PF00084.11.ls: domain 15 of 26, from 2029 to 2082: score 53.1, E = 8.4e-13 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ ++P+++NG+ + + + +y G+t+ +tC+ G++lvGs++ C+ KIAA1894 2029 CG-ELPTPPNGNKIGT--QTSY--GSTAIFTCDLGFMLVGSAVRECL 2070 edggGgWsppllgelPkC<-* G Ws + +C KIAA1894 2071 SS--GLWSESE----TRC 2082 PF00084.11.fs: domain 15 of 26, from 2029 to 2082: score 51.3, E = 2.9e-12 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ ++P+++NG+ + + + +y G+t+ +tC+ G++lvGs++ C+ KIAA1894 2029 CG-ELPTPPNGNKIGT--QTSY--GSTAIFTCDLGFMLVGSAVRECL 2070 edggGgWsppllgelPkC<-* G Ws + +C KIAA1894 2071 SS--GLWSESE----TRC 2082 PF00084.11.fs: domain 16 of 26, from 2087 to 2140: score 67.2, E = 4.8e-17 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ p i NG+v+ + +y y dtv+y+Cn+G+rl+Gss+ C+ KIAA1894 2087 CG-IPELIVNGQVIGE--NYGY--RDTVVYQCNPGFRLIGSSVRICQ 2128 edggGgWsppllgelPkC<-* d +Ws++l P+C KIAA1894 2129 QD--HNWSGQL----PSC 2140 PF00084.11.ls: domain 16 of 26, from 2087 to 2140: score 69.0, E = 1.4e-17 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ p i NG+v+ + +y y dtv+y+Cn+G+rl+Gss+ C+ KIAA1894 2087 CG-IPELIVNGQVIGE--NYGY--RDTVVYQCNPGFRLIGSSVRICQ 2128 edggGgWsppllgelPkC<-* d +Ws++l P+C KIAA1894 2129 QD--HNWSGQL----PSC 2140 PF00084.11.fs: domain 17 of 26, from 2145 to 2198: score 44.8, E = 1.5e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+ + Gr s + + +d+vt++Cn GY ++G++ ++C+ KIAA1894 2145 CG-HPGSPIYGRTSGN--GFNF--NDVVTFSCNIGYLMQGPTKAQCQ 2186 edggGgWsppllgelPkC<-* ++ +Ws+p+ P C KIAA1894 2187 AN--RQWSHPP----PMC 2198 PF00084.11.ls: domain 17 of 26, from 2145 to 2198: score 46.6, E = 7.7e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+ + Gr s + + +d+vt++Cn GY ++G++ ++C+ KIAA1894 2145 CG-HPGSPIYGRTSGN--GFNF--NDVVTFSCNIGYLMQGPTKAQCQ 2186 edggGgWsppllgelPkC<-* ++ +Ws+p+ P C KIAA1894 2187 AN--RQWSHPP----PMC 2198 PF00084.11.ls: domain 18 of 26, from 2203 to 2260: score 60.7, E = 4.5e-15 *->CplppPdieNGrvsss..kttyeypvGdtvtytCneGYrlvGsssit C+ +p+ + N + +s+ + ++++y G++v y Cn+GY l Gss++ KIAA1894 2203 CS-DPGIPANSKRESKieHGNFTY--GTVVFYDCNPGYFLFGSSVLI 2246 CtedggGgWsppllgelPkC<-* C+++ G+W+ pl P+C KIAA1894 2247 CQPN--GQWDKPL----PEC 2260 PF00084.11.fs: domain 18 of 26, from 2203 to 2260: score 58.9, E = 1.6e-14 *->CplppPdieNGrvsss..kttyeypvGdtvtytCneGYrlvGsssit C+ +p+ + N + +s+ + ++++y G++v y Cn+GY l Gss++ KIAA1894 2203 CS-DPGIPANSKRESKieHGNFTY--GTVVFYDCNPGYFLFGSSVLI 2246 CtedggGgWsppllgelPkC<-* C+++ G+W+ pl P+C KIAA1894 2247 CQPN--GQWDKPL----PEC 2260 PF00084.11.ls: domain 19 of 26, from 2265 to 2318: score 47.7, E = 3.6e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p++++N+ s + +y++ G+tv+y+C +l G ss tC+ KIAA1894 2265 CG-HPGVPPNAVLSGE--KYTF--GSTVHYSCTGKRSLLGQSSRTCQ 2306 edggGgWsppllgelPkC<-* + G+Ws+ P C KIAA1894 2307 LN--GHWSGSQ----PHC 2318 PF00084.11.fs: domain 19 of 26, from 2265 to 2318: score 45.9, E = 8e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p++++N+ s + +y++ G+tv+y+C +l G ss tC+ KIAA1894 2265 CG-HPGVPPNAVLSGE--KYTF--GSTVHYSCTGKRSLLGQSSRTCQ 2306 edggGgWsppllgelPkC<-* + G+Ws+ P C KIAA1894 2307 LN--GHWSGSQ----PHC 2318 PF00084.11.ls: domain 20 of 26, from 2326 to 2379: score 59.4, E = 1.1e-14 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+++ +G+ ++s +++ ++tv+y C++GY l Gs++ tC+ KIAA1894 2326 CG-DPGTPGHGSRQES--NFRT--KSTVRYACDTGYILHGSEERTCL 2367 edggGgWsppllgelPkC<-* ++ G+W+++ P+C KIAA1894 2368 AN--GSWTGRQ----PEC 2379 PF00084.11.fs: domain 20 of 26, from 2326 to 2379: score 57.6, E = 3.7e-14 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+++ +G+ ++s +++ ++tv+y C++GY l Gs++ tC+ KIAA1894 2326 CG-DPGTPGHGSRQES--NFRT--KSTVRYACDTGYILHGSEERTCL 2367 edggGgWsppllgelPkC<-* ++ G+W+++ P+C KIAA1894 2368 AN--GSWTGRQ----PEC 2379 PF00084.11.ls: domain 21 of 26, from 2384 to 2438: score 52.2, E = 1.6e-12 *->CplppPdieNGrvsss.kttyeypvGdtvtytCneGYrlvGsssitC C+ +p++ NG+v ++tt++ +v y+C eGY l+G+s+ +C KIAA1894 2384 CG-NPGTTANGKVFRIdGTTFSS----SVIYSCMEGYILSGPSVRQC 2425 tedggGgWsppllgelPkC<-* t++ G+Ws++l P C KIAA1894 2426 TAN--GTWSGTL----PNC 2438 PF00084.11.fs: domain 21 of 26, from 2384 to 2438: score 50.4, E = 5.6e-12 *->CplppPdieNGrvsss.kttyeypvGdtvtytCneGYrlvGsssitC C+ +p++ NG+v ++tt++ +v y+C eGY l+G+s+ +C KIAA1894 2384 CG-NPGTTANGKVFRIdGTTFSS----SVIYSCMEGYILSGPSVRQC 2425 tedggGgWsppllgelPkC<-* t++ G+Ws++l P C KIAA1894 2426 TAN--GTWSGTL----PNC 2438 PF00084.11.ls: domain 22 of 26, from 2443 to 2498: score 47.7, E = 3.7e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG..sssit C+ +p+ + NG y + G+ v+y C++GY+++ ++s+ t KIAA1894 2443 CG-DPGIPANGLRYGD--DYVV--GQNVSYMCQPGYTMELngSRIRT 2484 CtedggGgWsppllgelPkC<-* Ct + G+Ws+ + P+C KIAA1894 2485 CTIN--GTWSGVM----PTC 2498 PF00084.11.fs: domain 22 of 26, from 2443 to 2498: score 45.9, E = 8.1e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG..sssit C+ +p+ + NG y + G+ v+y C++GY+++ ++s+ t KIAA1894 2443 CG-DPGIPANGLRYGD--DYVV--GQNVSYMCQPGYTMELngSRIRT 2484 CtedggGgWsppllgelPkC<-* Ct + G+Ws+ + P+C KIAA1894 2485 CTIN--GTWSGVM----PTC 2498 PF00084.11.fs: domain 23 of 26, from 2503 to 2556: score 54.5, E = 3.3e-13 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp pP+i NGr + + ++ G +++y C +GY+l+ ++++tC+ KIAA1894 2503 CP-TPPQISNGRLEGT--NFDW--GFSISYICSPGYELSFPAVLTCV 2544 edggGgWsppllgelPkC<-* ++ G+Ws++ P+C KIAA1894 2545 GN--GTWSGEV----PQC 2556 PF00084.11.ls: domain 23 of 26, from 2503 to 2556: score 56.3, E = 9.5e-14 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt Cp pP+i NGr + + ++ G +++y C +GY+l+ ++++tC+ KIAA1894 2503 CP-TPPQISNGRLEGT--NFDW--GFSISYICSPGYELSFPAVLTCV 2544 edggGgWsppllgelPkC<-* ++ G+Ws++ P+C KIAA1894 2545 GN--GTWSGEV----PQC 2556 PF00084.11.fs: domain 24 of 26, from 2561 to 2614: score 44.0, E = 2.4e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+ + G+ + + ++ y + v+++Cn + lvGss+ C+ KIAA1894 2561 CG-DPGIPAQGKREGK--SFIY--QSEVSFSCNFPFILVGSSTRICQ 2602 edggGgWsppllgelPkC<-* +d G+Ws+ P C KIAA1894 2603 AD--GTWSGSS----PHC 2614 PF00084.11.ls: domain 24 of 26, from 2561 to 2614: score 45.8, E = 1.3e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C+ +p+ + G+ + + ++ y + v+++Cn + lvGss+ C+ KIAA1894 2561 CG-DPGIPAQGKREGK--SFIY--QSEVSFSCNFPFILVGSSTRICQ 2602 edggGgWsppllgelPkC<-* +d G+Ws+ P C KIAA1894 2603 AD--GTWSGSS----PHC 2614 PF00084.11.ls: domain 25 of 26, from 2622 to 2676: score 47.5, E = 4.2e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+++++G+ ++ + + vG++v++ C++G l+Gs++ tC+ KIAA1894 2622 CE-NPGVPRHGSQNNT---FGFQVGSVVQFHCKKGHLLQGSTTRTCL 2664 edggGgWsppllgelPkC<-* +d +Ws+ P+C KIAA1894 2665 PD--LTWSGIQ----PEC 2676 PF00084.11.fs: domain 25 of 26, from 2622 to 2676: score 45.7, E = 9.2e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvGsssitCt C +p+++++G+ ++ + + vG++v++ C++G l+Gs++ tC+ KIAA1894 2622 CE-NPGVPRHGSQNNT---FGFQVGSVVQFHCKKGHLLQGSTTRTCL 2664 edggGgWsppllgelPkC<-* +d +Ws+ P+C KIAA1894 2665 PD--LTWSGIQ----PEC 2676 PF00084.11.ls: domain 26 of 26, from 2681 to 2736: score 46.6, E = 8e-11 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG.sssitC C+ +p ++ +++v+ + ++ G t+ ytC++G+ l G+ ++ +C KIAA1894 2681 CK-QPETPAHANVVGM-DLPSH--GYTLIYTCQPGFFLAGgTEHRVC 2723 tedggGgWsppllgelPkC<-* + d +W++ P+C KIAA1894 2724 RSD--NTWTGKV----PIC 2736 PF00084.11.fs: domain 26 of 26, from 2681 to 2736: score 44.7, E = 1.6e-10 *->CplppPdieNGrvssskttyeypvGdtvtytCneGYrlvG.sssitC C+ +p ++ +++v+ + ++ G t+ ytC++G+ l G+ ++ +C KIAA1894 2681 CK-QPETPAHANVVGM-DLPSH--GYTLIYTCQPGFFLAGgTEHRVC 2723 tedggGgWsppllgelPkC<-* + d +W++ P+C KIAA1894 2724 RSD--NTWTGKV----PIC 2736 //