hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-16125194/chunk_1/iprscan-20080502-16125194.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1907 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00053.14.fs Laminin EGF-like (Domains III and V) 683.3 1.7e-202 18 PF00053.14.ls Laminin EGF-like (Domains III and V) 665.8 3.1e-197 15 PF00055.8.fs Laminin N-terminal (Domain VI) 116.8 2.5e-35 1 PF07974.3.fs EGF-like domain 99.4 1e-26 13 PF00052.9.fs Laminin B (Domain IV) 82.6 5.9e-23 2 PF00052.9.ls Laminin B (Domain IV) 84.5 3.1e-22 1 PF07974.3.ls EGF-like domain 82.2 1.5e-21 9 PF00008.17.fs EGF-like domain 43.6 2.5e-11 11 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00055.8.fs 1/1 13 101 .. 170 264 .] 116.8 2.5e-35 PF00053.14.ls 1/15 103 159 .. 1 59 [] 32.1 1.9e-06 PF00053.14.fs 1/18 103 159 .. 1 59 [] 30.1 4.4e-08 PF00053.14.fs 2/18 162 229 .. 1 59 [] 45.4 1.6e-12 PF00053.14.ls 2/15 162 229 .. 1 59 [] 47.4 4.5e-11 PF00053.14.fs 3/18 232 274 .. 1 59 [] 33.8 3.9e-09 PF00053.14.ls 3/15 232 274 .. 1 59 [] 35.5 1.7e-07 PF00053.14.fs 4/18 297 341 .. 1 59 [] 46.9 6e-13 PF00053.14.ls 4/15 297 341 .. 1 59 [] 48.7 1.9e-11 PF00053.14.ls 5/15 344 387 .. 1 59 [] 42.2 1.6e-09 PF00053.14.fs 5/18 344 387 .. 1 59 [] 40.5 4.5e-11 PF00053.14.ls 6/15 390 432 .. 1 59 [] 53.8 5.4e-13 PF00053.14.fs 6/18 390 432 .. 1 59 [] 52.1 2e-14 PF00053.14.ls 7/15 435 477 .. 1 59 [] 42.3 1.5e-09 PF00053.14.fs 7/18 435 477 .. 1 59 [] 40.6 4e-11 PF00053.14.ls 8/15 480 523 .. 1 59 [] 45.8 1.3e-10 PF00053.14.fs 8/18 480 528 .. 1 59 [] 45.0 2.2e-12 PF00053.14.ls 9/15 524 576 .. 1 59 [] 30.3 6.5e-06 PF00053.14.fs 9/18 547 576 .. 28 59 .] 38.7 1.4e-10 PF00053.14.fs 10/18 579 629 .. 1 59 [] 42.8 9.4e-12 PF00053.14.ls 10/15 579 629 .. 1 59 [] 44.7 3e-10 PF00053.14.fs 11/18 632 664 .. 1 42 [. 28.8 1.1e-07 PF00053.14.ls 11/15 632 673 .. 1 59 [] 20.3 0.00019 PF00053.14.fs 12/18 1241 1289 .. 1 59 [] 57.9 3.9e-16 PF00053.14.ls 12/15 1241 1284 .. 1 59 [] 56.4 8.5e-14 PF00053.14.ls 13/15 1331 1377 .. 1 59 [] 46.3 9.3e-11 PF00053.14.fs 14/18 1331 1377 .. 1 59 [] 44.6 2.9e-12 PF00053.14.fs 15/18 1380 1428 .. 1 59 [] 65.8 2.1e-18 PF00053.14.ls 14/15 1380 1428 .. 1 59 [] 67.6 3.7e-17 PF00052.9.fs 2/2 1496 1632 .. 1 150 [] 82.6 6e-23 PF00052.9.ls 1/1 1496 1632 .. 1 150 [] 84.5 3.1e-22 PF00053.14.fs 16/18 1634 1664 .. 28 59 .] 15.1 0.001 PF00053.14.ls 15/15 1667 1713 .. 1 59 [] 52.5 1.3e-12 PF00053.14.fs 17/18 1667 1713 .. 1 59 [] 50.7 4.9e-14 Alignments of top-scoring domains: PF00055.8.fs: domain 1 of 1, from 13 to 101: score 116.8, E = 2.5e-35 *->eddvlCTSrYSdiePlteGEViFsvLeGRPsadifDpYSprlQewlk +d ++CT +YS+i+Pl++GE+ s+ +GRP a +f Sp l e++k KIAA1907 13 DDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSY-SPLLREFTK 58 aTniRitLtRLhTLGDnLldsSHRelkeL.dpevlekYYYAIsDivVGG< aTn R+++ R +TL L++ k L+dp v+++YYY+I+Di++GG KIAA1907 59 ATNVRLRFLRTNTLLGHLMG------KALrDPTVTRRYYYSIKDISIGG 101 -* KIAA1907 - - PF00053.14.ls: domain 1 of 15, from 103 to 159: score 32.1, E = 1.9e-06 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C++h+ d Cd +++ + + qC C++n+ G CdrC pG+ KIAA1907 103 CVCHGHA----DACDA-KDPTDPFRLQCT-CQHNTCGGTCDRCCPGF 143 yglpsg....dpgqgC<-* + p+++ + ++++ C KIAA1907 144 NQQPWKpataNSANEC 159 PF00053.14.fs: domain 1 of 18, from 103 to 159: score 30.1, E = 4.4e-08 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C++h+ d Cd +++ + + qC C++n+ G CdrC pG+ KIAA1907 103 CVCHGHA----DACDA-KDPTDPFRLQCT-CQHNTCGGTCDRCCPGF 143 yglpsg....dpgqgC<-* + p+++ + ++++ C KIAA1907 144 NQQPWKpataNSANEC 159 PF00053.14.fs: domain 2 of 18, from 162 to 229: score 45.4, E = 1.6e-12 *->CdCnphGslsddtCdsddelf...........geetGqClkCkpnvt C+C +h+ +C+ d+e+ +++ +++ +++ +G+C +C++++t KIAA1907 162 CNCYGHA----TDCYYDPEVDrrrasqsldgtYQGGGVCIDCQHHTT 204 GrrCdrCkpGyyglpsg..dpgqgC<-* G +C+rC+pG+y+ p+ + d+++ C KIAA1907 205 GVNCERCLPGFYRSPNHplDSPHVC 229 PF00053.14.ls: domain 2 of 15, from 162 to 229: score 47.4, E = 4.5e-11 *->CdCnphGslsddtCdsddelf...........geetGqClkCkpnvt C+C +h+ +C+ d+e+ +++ +++ +++ +G+C +C++++t KIAA1907 162 CNCYGHA----TDCYYDPEVDrrrasqsldgtYQGGGVCIDCQHHTT 204 GrrCdrCkpGyyglpsg..dpgqgC<-* G +C+rC+pG+y+ p+ + d+++ C KIAA1907 205 GVNCERCLPGFYRSPNHplDSPHVC 229 PF00053.14.fs: domain 3 of 18, from 232 to 274: score 33.8, E = 3.9e-09 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C + + tC tG+C C+pn++G+rCd C++G+ KIAA1907 232 CNCESDFTDG--TCED-------LTGRCY-CRPNFSGERCDVCAEGF 268 yglpsgdpgqgC<-* +++ +C KIAA1907 269 T-----GFP-SC 274 PF00053.14.ls: domain 3 of 15, from 232 to 274: score 35.5, E = 1.7e-07 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C + + tC tG+C C+pn++G+rCd C++G+ KIAA1907 232 CNCESDFTDG--TCED-------LTGRCY-CRPNFSGERCDVCAEGF 268 yglpsgdpgqgC<-* +++ +C KIAA1907 269 T-----GFP-SC 274 PF00053.14.fs: domain 4 of 18, from 297 to 341: score 46.9, E = 6e-13 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy CdC+ +G+++ C d++ G+Cl Ckpn++G++C+ C+pG+ KIAA1907 297 CDCSAAGTQG-NACRKDPR-----VGRCL-CKPNFQGTHCELCAPGF 336 yglpsgdpgqgC<-* y +pg C KIAA1907 337 Y-----GPG--C 341 PF00053.14.ls: domain 4 of 15, from 297 to 341: score 48.7, E = 1.9e-11 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy CdC+ +G+++ C d++ G+Cl Ckpn++G++C+ C+pG+ KIAA1907 297 CDCSAAGTQG-NACRKDPR-----VGRCL-CKPNFQGTHCELCAPGF 336 yglpsgdpgqgC<-* y +pg C KIAA1907 337 Y-----GPG--C 341 PF00053.14.ls: domain 5 of 15, from 344 to 387: score 42.2, E = 1.6e-09 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+ G + d+Cd+ tGqC+ C+ +++G CdrC+pGy KIAA1907 344 CQCSSPGVAD-DRCDP-------DTGQCR-CRVGFEGATCDRCAPGY 381 yglpsgdpgqgC<-* + ++ C KIAA1907 382 F-----HFP-LC 387 PF00053.14.fs: domain 5 of 18, from 344 to 387: score 40.5, E = 4.5e-11 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+ G + d+Cd+ tGqC+ C+ +++G CdrC+pGy KIAA1907 344 CQCSSPGVAD-DRCDP-------DTGQCR-CRVGFEGATCDRCAPGY 381 yglpsgdpgqgC<-* + ++ C KIAA1907 382 F-----HFP-LC 387 PF00053.14.ls: domain 6 of 15, from 390 to 432: score 53.8, E = 5.4e-13 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C+p+G+l+ + Cd G+Cl C+p ++G++CdrC+pGy KIAA1907 390 CGCSPAGTLP-EGCDE--------AGRCL-CQPEFAGPHCDRCRPGY 426 yglpsgdpgqgC<-* + +++ +C KIAA1907 427 H-----GFP-NC 432 PF00053.14.fs: domain 6 of 18, from 390 to 432: score 52.1, E = 2e-14 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C+p+G+l+ + Cd G+Cl C+p ++G++CdrC+pGy KIAA1907 390 CGCSPAGTLP-EGCDE--------AGRCL-CQPEFAGPHCDRCRPGY 426 yglpsgdpgqgC<-* + +++ +C KIAA1907 427 H-----GFP-NC 432 PF00053.14.ls: domain 7 of 15, from 435 to 477: score 42.3, E = 1.5e-09 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+p+G+l+ C +G C+ C+p++tG+ C +C pG+ KIAA1907 435 CTCDPRGALD-QLCGA--------GGLCR-CRPGYTGTACQECSPGF 471 yglpsgdpgqgC<-* + +++ +C KIAA1907 472 H-----GFP-SC 477 PF00053.14.fs: domain 7 of 18, from 435 to 477: score 40.6, E = 4e-11 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+p+G+l+ C +G C+ C+p++tG+ C +C pG+ KIAA1907 435 CTCDPRGALD-QLCGA--------GGLCR-CRPGYTGTACQECSPGF 471 yglpsgdpgqgC<-* + +++ +C KIAA1907 472 H-----GFP-SC 477 PF00053.14.ls: domain 8 of 15, from 480 to 523: score 45.8, E = 1.3e-10 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+ Gsl+ + Cd+ ++GqC+ C+p vtG rCd C pG KIAA1907 480 CHCSAEGSLH-AACDP-------RSGQCS-CRPRVTGLRCDTCVPGA 517 yglpsgdpgqgC<-* y +++ C KIAA1907 518 Y-----NFP-YC 523 PF00053.14.fs: domain 8 of 18, from 480 to 528: score 45.0, E = 2.2e-12 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C+ Gsl+ + Cd+ ++GqC+ C+p vtG rCd C pG KIAA1907 480 CHCSAEGSLH-AACDP-------RSGQCS-CRPRVTGLRCDTCVPGA 517 yglpsgdpgqgC<-* y++p + g +C KIAA1907 518 YNFPYCEAG-SC 528 PF00053.14.ls: domain 9 of 15, from 524 to 576: score 30.3, E = 6.5e-06 *->CdCnphGslsddtCdsddelf......geetGqClkCkpnvtGrrCd + ++C++ ++l + ++ e + C C+ +v+G+ Cd KIAA1907 524 -----EA----GSCHP-AGLApvdpalPEAQVPCM-CRAHVEGPSCD 559 rCkpGyyglpsgdpgqgC<-* rCkpG++gl+ ++++gC KIAA1907 560 RCKPGFWGLSP-SNPEGC 576 PF00053.14.fs: domain 9 of 18, from 547 to 576: score 38.7, E = 1.4e-10 *->ClkCkpnvtGrrCdrCkpGyyglpsgdpgqgC<-* C C+ +v+G+ CdrCkpG++gl+ ++++gC KIAA1907 547 CM-CRAHVEGPSCDRCKPGFWGLSP-SNPEGC 576 PF00053.14.fs: domain 10 of 18, from 579 to 629: score 42.8, E = 9.4e-12 *->CdCnphGslsd.dtCdsddelfgeetGqClkCkpnvtGrrCdrCkpG C C+++G+l++ ++C + tGqC Ckp+v G+ C Ck+G KIAA1907 579 CSCDLRGTLGGvAECQP-------GTGQCF-CKPHVCGQACASCKDG 617 yyglpsgdpgqgC<-* ++gl +gC KIAA1907 618 FFGLDQ-ADYFGC 629 PF00053.14.ls: domain 10 of 15, from 579 to 629: score 44.7, E = 3e-10 *->CdCnphGslsd.dtCdsddelfgeetGqClkCkpnvtGrrCdrCkpG C C+++G+l++ ++C + tGqC Ckp+v G+ C Ck+G KIAA1907 579 CSCDLRGTLGGvAECQP-------GTGQCF-CKPHVCGQACASCKDG 617 yyglpsgdpgqgC<-* ++gl +gC KIAA1907 618 FFGLDQ-ADYFGC 629 PF00053.14.fs: domain 11 of 18, from 632 to 664: score 28.8, E = 1.1e-07 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdr<-* C C+ G+l+ +C + +tG+C+ C+pn++G+ C + KIAA1907 632 CRCDIGGALG-QSCEP-------RTGVCR-CRPNTQGPTCSE 664 PF00053.14.ls: domain 11 of 15, from 632 to 673: score 20.3, E = 0.00019 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C+ G+l+ +C + +tG+C+ C+pn++G+ C + + + KIAA1907 632 CRCDIGGALG-QSCEP-------RTGVCR-CRPNTQGPTCSEPARDH 669 yglpsgdpgqgC<-* y p KIAA1907 670 Y-----LPD--- 673 PF00053.14.fs: domain 12 of 18, from 1241 to 1289: score 57.9, E = 3.9e-16 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C+++G+++ +tC + ++GqC+ C +v Gr+C rC+ Gy KIAA1907 1241 CGCHEVGATG-PTCEP-------FGGQCP-CHAHVIGRDCSRCATGY 1278 yglpsgdpgqgC<-* +g+p++ p+ +C KIAA1907 1279 WGFPNCRPC-DC 1289 PF00053.14.ls: domain 12 of 15, from 1241 to 1284: score 56.4, E = 8.5e-14 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C C+++G+++ +tC + ++GqC+ C +v Gr+C rC+ Gy KIAA1907 1241 CGCHEVGATG-PTCEP-------FGGQCP-CHAHVIGRDCSRCATGY 1278 yglpsgdpgqgC<-* + +++ +C KIAA1907 1279 W-----GFP-NC 1284 PF00053.14.ls: domain 13 of 15, from 1331 to 1377: score 46.3, E = 9.3e-11 *->CdCnphGslsd..dtCdsddelfgeetGqClkCkpnvtGrrCdrCkp C+C++ G + +++tCd +GqC C+pnvtGrrCd C p KIAA1907 1331 CNCSGPGIQELtdPTCDT-------DSGQCK-CRPNVTGRRCDTCSP 1369 GyyglpsgdpgqgC<-* G++ + + C KIAA1907 1370 GFH-----GYP-RC 1377 PF00053.14.fs: domain 14 of 18, from 1331 to 1377: score 44.6, E = 2.9e-12 *->CdCnphGslsd..dtCdsddelfgeetGqClkCkpnvtGrrCdrCkp C+C++ G + +++tCd +GqC C+pnvtGrrCd C p KIAA1907 1331 CNCSGPGIQELtdPTCDT-------DSGQCK-CRPNVTGRRCDTCSP 1369 GyyglpsgdpgqgC<-* G++ + + C KIAA1907 1370 GFH-----GYP-RC 1377 PF00053.14.fs: domain 15 of 18, from 1380 to 1428: score 65.8, E = 2.1e-18 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy CdC+++G+ + + Cd+ tGqC Ck+nv+G++Cd+C G+ KIAA1907 1380 CDCHEAGTAP-GVCDP-------LTGQCY-CKENVQGPKCDQCSLGT 1417 yglpsgdpgqgC<-* + l +++gC KIAA1907 1418 FSLDA-ANPKGC 1428 PF00053.14.ls: domain 14 of 15, from 1380 to 1428: score 67.6, E = 3.7e-17 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy CdC+++G+ + + Cd+ tGqC Ck+nv+G++Cd+C G+ KIAA1907 1380 CDCHEAGTAP-GVCDP-------LTGQCY-CKENVQGPKCDQCSLGT 1417 yglpsgdpgqgC<-* + l +++gC KIAA1907 1418 FSLDA-ANPKGC 1428 PF00052.9.fs: domain 2 of 2, from 1496 to 1632: score 82.6, E = 6e-23 *->YWrlPekFLGDkvtaYGGkLkYsvafdgPvegvgstsnseadViLkG YW++P +LGD v +YGG+L Y++ v + s +dV+L G KIAA1907 1496 YWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQG 1542 nglrlsvplraqgnslQPseervkvtvrlhE.tfwKdfqsvpekaatred n+ + ++++ + + + + +l E++f+ ++ ++re+ KIAA1907 1543 NQMSITF---LEPAYP-TPGHVHRGQLQLVEgNFR---HTETRNTVSREE 1585 llsvLanLtaiLIRATYNsakqaqsrLddVsLeiAvDrpgaqglaEevvA l++vLa L+ + IRA + s+ +L V Le+A +p++qg + A KIAA1907 1586 LMMVLASLEQLQIRALF-SQISSAVSLRRVALEVA--SPAGQG----ALA 1628 aeVE<-* + VE KIAA1907 1629 SNVE 1632 PF00052.9.ls: domain 1 of 1, from 1496 to 1632: score 84.5, E = 3.1e-22 *->YWrlPekFLGDkvtaYGGkLkYsvafdgPvegvgstsnseadViLkG YW++P +LGD v +YGG+L Y++ v + s +dV+L G KIAA1907 1496 YWQAPPSYLGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQG 1542 nglrlsvplraqgnslQPseervkvtvrlhE.tfwKdfqsvpekaatred n+ + ++++ + + + + +l E++f+ ++ ++re+ KIAA1907 1543 NQMSITF---LEPAYP-TPGHVHRGQLQLVEgNFR---HTETRNTVSREE 1585 llsvLanLtaiLIRATYNsakqaqsrLddVsLeiAvDrpgaqglaEevvA l++vLa L+ + IRA + s+ +L V Le+A +p++qg + A KIAA1907 1586 LMMVLASLEQLQIRALF-SQISSAVSLRRVALEVA--SPAGQG----ALA 1628 aeVE<-* + VE KIAA1907 1629 SNVE 1632 PF00053.14.fs: domain 16 of 18, from 1634 to 1664: score 15.1, E = 0.001 *->ClkCkpnvtGrrCdrCkpGyyglpsgdpgqgC<-* Cl C + G+ C +C+pG+y++ +g + + C KIAA1907 1634 CL-CPASYRGDSCQECAPGFYRDVKGLFLGRC 1664 PF00053.14.ls: domain 15 of 15, from 1667 to 1713: score 52.5, E = 1.3e-12 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C++h+ d+C + +G+C++C++n++G +C+rC+ G+ KIAA1907 1667 CQCHGHS----DRCLP-------GSGVCVDCQHNTEGAHCERCQAGF 1702 yglpsgdpgqgC<-* + dp C KIAA1907 1703 MSSRD-DPSAPC 1713 PF00053.14.fs: domain 17 of 18, from 1667 to 1713: score 50.7, E = 4.9e-14 *->CdCnphGslsddtCdsddelfgeetGqClkCkpnvtGrrCdrCkpGy C+C++h+ d+C + +G+C++C++n++G +C+rC+ G+ KIAA1907 1667 CQCHGHS----DRCLP-------GSGVCVDCQHNTEGAHCERCQAGF 1702 yglpsgdpgqgC<-* + dp C KIAA1907 1703 MSSRD-DPSAPC 1713 //