hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-16360660/chunk_1/iprscan-20080502-16360660.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1921 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF01344.15.ls Kelch motif 199.3 8.2e-57 6 PF01344.15.fs Kelch motif 187.4 3.3e-53 6 PF07707.5.ls BTB And C-terminal Kelch 164.2 3.1e-46 1 PF07707.5.fs BTB And C-terminal Kelch 162.2 1.2e-45 1 PF07646.5.ls Kelch motif 107.5 3.6e-29 5 PF07646.5.fs Kelch motif 98.2 2.3e-26 5 PF00651.21.fs BTB/POZ domain 49.6 2.4e-13 1 PF00651.21.ls BTB/POZ domain 10.1 0.00046 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00651.21.ls 1/1 26 101 .. 1 135 [] 10.1 0.00046 PF00651.21.fs 1/1 44 101 .. 66 135 .] 49.6 2.4e-13 PF07707.5.fs 1/1 106 208 .. 1 103 [] 162.2 1.2e-45 PF07707.5.ls 1/1 106 208 .. 1 103 [] 164.2 3.1e-46 PF01344.15.fs 1/6 243 292 .. 1 45 [] 16.9 0.00059 PF07646.5.fs 1/5 243 292 .. 1 54 [] 16.9 0.00097 PF07646.5.ls 1/5 243 292 .. 1 54 [] 18.9 0.018 PF01344.15.ls 1/6 243 292 .. 1 45 [] 18.9 0.017 PF01344.15.ls 2/6 295 340 .. 1 45 [] 29.4 1.2e-05 PF01344.15.fs 2/6 295 340 .. 1 45 [] 27.4 6.1e-07 PF01344.15.fs 3/6 342 387 .. 1 45 [] 51.3 9.3e-14 PF07646.5.fs 3/5 342 387 .. 1 54 [] 32.7 5e-08 PF07646.5.ls 3/5 342 387 .. 1 54 [] 34.5 3.3e-07 PF01344.15.ls 3/6 342 387 .. 1 45 [] 53.3 7.3e-13 PF01344.15.fs 4/6 389 435 .. 1 45 [] 36.8 1.2e-09 PF07646.5.fs 4/5 389 435 .. 1 54 [] 22.5 2.9e-05 PF01344.15.ls 4/6 389 435 .. 1 45 [] 38.8 1.7e-08 PF07646.5.ls 4/5 389 435 .. 1 54 [] 24.4 0.00037 PF07646.5.fs 5/5 480 527 .. 1 54 [] 19.6 0.00018 PF01344.15.fs 6/6 480 527 .. 1 45 [] 50.8 1.3e-13 PF01344.15.ls 6/6 480 527 .. 1 45 [] 52.8 1e-12 PF07646.5.ls 5/5 480 527 .. 1 54 [] 21.5 0.0029 Alignments of top-scoring domains: PF00651.21.ls: domain 1 of 1, from 26 to 101: score 10.1, E = 0.00046 *->lnelrkqgelcDVtLvvgdgsgrydvgkkfkAHKavLaacSpYFkal r v+d+ g+ KIAA1921 26 VSVPRS----------VQDS------GQ------------------- 37 FtgqfkesiteeessvsseieledvspedfealLefiYtgelsitqdqks g+ e+ e+ l++ +++++e+lLef Ytg l i+ KIAA1921 38 --GG-------REKL---ELVLSNLQADVLELLLEFVYTGSLVID----- 70 PssckseenvedlLaaAadllqipslvdaCeefliksl<-* +n+ lL+aA +++q + ++C +fl k+l KIAA1921 71 ------SANAKTLLEAA-SKFQFHTFCKVCVSFLEKQL 101 PF00651.21.fs: domain 1 of 1, from 44 to 101: score 49.6, E = 2.4e-13 *->eieledvspedfealLefiYtgelsitqdqksPssckseenvedlLa e+ l++ +++++e+lLef Ytg l i+ +n+ lL+ KIAA1921 44 ELVLSNLQADVLELLLEFVYTGSLVID-----------SANAKTLLE 79 aAadllqipslvdaCeefliksl<-* aA +++q + ++C +fl k+l KIAA1921 80 AA-SKFQFHTFCKVCVSFLEKQL 101 PF07707.5.fs: domain 1 of 1, from 106 to 208: score 162.2, E = 1.2e-45 *->CLgIrrfAdaygceeLaeaAdrfilqnFleVakseEFlqLskeqLie CLg++ +A+a++c+eL+++A++f+lq F+eVa++eE l++sk+++i KIAA1921 106 CLGVLAMAEAMQCSELYHMAKAFALQIFPEVAAQEEILSISKDDFIA 152 lLssDeLnVpsEeeVfeAvmrWvkhdvenRkkhlpeLLshVRLpLLspky ++s+D+Ln++ Ee V+e v++W+k+d+++R ++++eLL+ VRLp+++p+y KIAA1921 153 YVSNDSLNTKAEELVYETVIKWIKKDPATRTQYAAELLAVVRLPFIHPSY 202 Llevve<-* Ll+vv KIAA1921 203 LLNVVD 208 PF07707.5.ls: domain 1 of 1, from 106 to 208: score 164.2, E = 3.1e-46 *->CLgIrrfAdaygceeLaeaAdrfilqnFleVakseEFlqLskeqLie CLg++ +A+a++c+eL+++A++f+lq F+eVa++eE l++sk+++i KIAA1921 106 CLGVLAMAEAMQCSELYHMAKAFALQIFPEVAAQEEILSISKDDFIA 152 lLssDeLnVpsEeeVfeAvmrWvkhdvenRkkhlpeLLshVRLpLLspky ++s+D+Ln++ Ee V+e v++W+k+d+++R ++++eLL+ VRLp+++p+y KIAA1921 153 YVSNDSLNTKAEELVYETVIKWIKKDPATRTQYAAELLAVVRLPFIHPSY 202 Llevve<-* Ll+vv KIAA1921 203 LLNVVD 208 PF01344.15.fs: domain 1 of 6, from 243 to 292: score 16.9, E = 0.00059 *->pRsgagvvvldgkiYviGGydg.....qslnsvevYDpetntWtklp + + ++ + +i +GG+ + +++sl v +++p +n+W +l+ KIAA1921 243 RTRPRLSAGVAEVIVLVGGRQMvgmtqRSLVAVTCWNPQNNKWYPLA 289 smp<-* s+p KIAA1921 290 SLP 292 PF07646.5.fs: domain 1 of 5, from 243 to 292: score 16.9, E = 0.00097 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ++ p +s+ + + +++vGG+ g+ s+ + +++p+ n+W KIAA1921 243 RTRPRLSAGVAEVIVLVGGR----QMVGMTQRSLVAVTCWNPQNNKW 285 eklpalp<-* +l++lp KIAA1921 286 YPLASLP 292 PF07646.5.ls: domain 1 of 5, from 243 to 292: score 18.9, E = 0.018 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ++ p +s+ + + +++vGG+ g+ s+ + +++p+ n+W KIAA1921 243 RTRPRLSAGVAEVIVLVGGR----QMVGMTQRSLVAVTCWNPQNNKW 285 eklpalp<-* +l++lp KIAA1921 286 YPLASLP 292 PF01344.15.ls: domain 1 of 6, from 243 to 292: score 18.9, E = 0.017 *->pRsgagvvvldgkiYviGGydg.....qslnsvevYDpetntWtklp + + ++ + +i +GG+ + +++sl v +++p +n+W +l+ KIAA1921 243 RTRPRLSAGVAEVIVLVGGRQMvgmtqRSLVAVTCWNPQNNKWYPLA 289 smp<-* s+p KIAA1921 290 SLP 292 PF01344.15.ls: domain 2 of 6, from 295 to 340: score 29.4, E = 1.2e-05 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< R +++vv+ ++ iY GG+ +++ l +v++Y + W ++ m+ KIAA1921 295 DREFFSVVSAGDNIYLSGGMESgVTLADVWCYMSLLDNWNLVSRMT 340 -* KIAA1921 - - PF01344.15.fs: domain 2 of 6, from 295 to 340: score 27.4, E = 6.1e-07 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< R +++vv+ ++ iY GG+ +++ l +v++Y + W ++ m+ KIAA1921 295 DREFFSVVSAGDNIYLSGGMESgVTLADVWCYMSLLDNWNLVSRMT 340 -* KIAA1921 - - PF01344.15.fs: domain 3 of 6, from 342 to 387: score 51.3, E = 9.3e-14 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< pR+++ + v+dgkiY GG ++ ve+YD+ tn+W+ ++++p KIAA1921 342 PRCRHNSLVYDGKIYTLGGLGVaGNVDHVERYDTITNQWEAVAPLP 387 -* KIAA1921 - - PF07646.5.fs: domain 3 of 5, from 342 to 387: score 32.7, E = 5e-08 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW pr++h s v++gk+y GG + + +++ ++d+ tn+W KIAA1921 342 PRCRHNSLVYDGKIYTLGGL--------GVAGNVDHVERYDTITNQW 380 eklpalp<-* e +++lp KIAA1921 381 EAVAPLP 387 PF07646.5.ls: domain 3 of 5, from 342 to 387: score 34.5, E = 3.3e-07 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW pr++h s v++gk+y GG + + +++ ++d+ tn+W KIAA1921 342 PRCRHNSLVYDGKIYTLGGL--------GVAGNVDHVERYDTITNQW 380 eklpalp<-* e +++lp KIAA1921 381 EAVAPLP 387 PF01344.15.ls: domain 3 of 6, from 342 to 387: score 53.3, E = 7.3e-13 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< pR+++ + v+dgkiY GG ++ ve+YD+ tn+W+ ++++p KIAA1921 342 PRCRHNSLVYDGKIYTLGGLGVaGNVDHVERYDTITNQWEAVAPLP 387 -* KIAA1921 - - PF01344.15.fs: domain 4 of 6, from 389 to 435: score 36.8, E = 1.2e-09 *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntWtklpsmp + ++a+++v++gkiYv+GG++ +++ +Y p tntW+++ s++ KIAA1921 389 AVHSAAATVCGGKIYVFGGVNEagRAAGVLQSYVPQTNTWSFIESPM 435 <-* KIAA1921 - - PF07646.5.fs: domain 4 of 5, from 389 to 435: score 22.5, E = 2.9e-05 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ++ a++v+ggk+yv+GG+ + + + +l+ + p+tn+W KIAA1921 389 AVHSAAATVCGGKIYVFGGV-------NEAGRAAGVLQSYVPQTNTW 428 eklpalp<-* + + ++ KIAA1921 429 SFIESPM 435 PF01344.15.ls: domain 4 of 6, from 389 to 435: score 38.8, E = 1.7e-08 *->pRsgagvvvldgkiYviGGydg..qslnsvevYDpetntWtklpsmp + ++a+++v++gkiYv+GG++ +++ +Y p tntW+++ s++ KIAA1921 389 AVHSAAATVCGGKIYVFGGVNEagRAAGVLQSYVPQTNTWSFIESPM 435 <-* KIAA1921 - - PF07646.5.ls: domain 4 of 5, from 389 to 435: score 24.4, E = 0.00037 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ++ a++v+ggk+yv+GG+ + + + +l+ + p+tn+W KIAA1921 389 AVHSAAATVCGGKIYVFGGV-------NEAGRAAGVLQSYVPQTNTW 428 eklpalp<-* + + ++ KIAA1921 429 SFIESPM 435 PF07646.5.fs: domain 5 of 5, from 480 to 527: score 19.6, E = 0.00018 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +r +++vv++gk+y GG+ ++++ + + p tn+W KIAA1921 480 SRQFCSAVVLDGKIYATGGI------VSSEGPALGNMEAYEPTTNTW 520 eklpalp<-* + lp +p KIAA1921 521 TLLPHMP 527 PF01344.15.fs: domain 6 of 6, from 480 to 527: score 50.8, E = 1.3e-13 *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm R ++++vvldgkiY++GG ++++ +l + e+Y p+tntWt lp m KIAA1921 480 SRQFCSAVVLDGKIYATGGIVSsegPALGNMEAYEPTTNTWTLLPHM 526 p<-* p KIAA1921 527 P 527 PF01344.15.ls: domain 6 of 6, from 480 to 527: score 52.8, E = 1e-12 *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm R ++++vvldgkiY++GG ++++ +l + e+Y p+tntWt lp m KIAA1921 480 SRQFCSAVVLDGKIYATGGIVSsegPALGNMEAYEPTTNTWTLLPHM 526 p<-* p KIAA1921 527 P 527 PF07646.5.ls: domain 5 of 5, from 480 to 527: score 21.5, E = 0.0029 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW +r +++vv++gk+y GG+ ++++ + + p tn+W KIAA1921 480 SRQFCSAVVLDGKIYATGGI------VSSEGPALGNMEAYEPTTNTW 520 eklpalp<-* + lp +p KIAA1921 521 TLLPHMP 527 //