hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-19145391/chunk_1/iprscan-20080502-19145391.nocrc
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Query sequence: KIAA2016
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00621.11.fs RhoGEF domain                                  144.1    2.2e-42   1
PF00621.11.ls RhoGEF domain                                  145.9      1e-40   1
PF00169.19.fs PH domain                                       76.2      1e-22   2
PF00169.19.ls PH domain                                       77.6    3.7e-20   2
PF00595.14.fs PDZ domain (Also known as DHR or GLGF)          30.9      5e-08   1
PF00595.14.ls PDZ domain (Also known as DHR or GLGF)          32.9      1e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00169.19.ls   1/2     521   634 ..     1    92 []    72.6  1.2e-18
PF00169.19.fs   1/2     521   634 ..     1    92 []    70.5  5.2e-21
PF00595.14.fs   1/1     904   985 ..     1    86 []    30.9    5e-08
PF00595.14.ls   1/1     904   985 ..     1    86 []    32.9    1e-06
PF00621.11.fs   1/1    1117  1306 ..     1   207 []   144.1  2.2e-42
PF00621.11.ls   1/1    1117  1306 ..     1   207 []   145.9    1e-40

Alignments of top-scoring domains:
PF00169.19.ls: domain 1 of 2, from 521 to 634: score 72.6, E = 1.2e-18
                   *->vikeGwLlkkg.............gkkswkkRyfvLfddvLlyykdk
                      v k GwL+ k   + +++++ +  ++++wk+++++L++ +Ll+y+  
    KIAA2016   521    VRKAGWLFFKPlvtvqkerklelvARRKWKQYWVTLKGCTLLFYETY 567  

                   k.......kkpkgsipLsgiqvtkvpdn.krkncFeirt.dretlllqae
                   ++++ ++++ p+  +  +++ v  vp+ +k++n+F+++++ ++++l+qa+
    KIAA2016   568 GknsmdqsSAPRCALFAEDSIVQSVPEHpKKENVFCLSNsFGDVYLFQAT 617  

                   seeerkeWvkaiqsair<-*
                   s+ +++ Wv+a +sa++   
    KIAA2016   618 SQTDLENWVTAVHSACA    634  

PF00169.19.fs: domain 1 of 2, from 521 to 634: score 70.5, E = 5.2e-21
                   *->vikeGwLlkkg.............gkkswkkRyfvLfddvLlyykdk
                      v k GwL+ k   + +++++ +  ++++wk+++++L++ +Ll+y+  
    KIAA2016   521    VRKAGWLFFKPlvtvqkerklelvARRKWKQYWVTLKGCTLLFYETY 567  

                   k.......kkpkgsipLsgiqvtkvpdn.krkncFeirt.dretlllqae
                   ++++ ++++ p+  +  +++ v  vp+ +k++n+F+++++ ++++l+qa+
    KIAA2016   568 GknsmdqsSAPRCALFAEDSIVQSVPEHpKKENVFCLSNsFGDVYLFQAT 617  

                   seeerkeWvkaiqsair<-*
                   s+ +++ Wv+a +sa++   
    KIAA2016   618 SQTDLENWVTAVHSACA    634  

PF00595.14.fs: domain 1 of 1, from 904 to 985: score 30.9, E = 5e-08
                   *->evtlekedkrgglGfsikggsdkga.dkgifvsevlpGsgaAeagGr
                      +v+l k  +   +Gf +  + d+++++  if+s+vlp+ g A   G 
    KIAA2016   904    DVQLTKTGSVCDFGFAVTAQVDERQhLSRIFISDVLPD-GLAYGEG- 948  

                   LqaGDqIlsvNGqdlenlsheeavlalkgsggsevtLtvl<-*
                   L++G  I+ +NG+ +++l ++++++al + +  +v Lt++   
    KIAA2016   949 LRKGNEIMTLNGEAVSDL-DLKQMEALFSEK--SVGLTLI    985  

PF00595.14.ls: domain 1 of 1, from 904 to 985: score 32.9, E = 1e-06
                   *->evtlekedkrgglGfsikggsdkga.dkgifvsevlpGsgaAeagGr
                      +v+l k  +   +Gf +  + d+++++  if+s+vlp+ g A   G 
    KIAA2016   904    DVQLTKTGSVCDFGFAVTAQVDERQhLSRIFISDVLPD-GLAYGEG- 948  

                   LqaGDqIlsvNGqdlenlsheeavlalkgsggsevtLtvl<-*
                   L++G  I+ +NG+ +++l ++++++al + +  +v Lt++   
    KIAA2016   949 LRKGNEIMTLNGEAVSDL-DLKQMEALFSEK--SVGLTLI    985  

PF00621.11.fs: domain 1 of 1, from 1117 to 1306: score 144.1, E = 2.2e-42
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      v+ El+ TEk Yv+dL  l   y++pL+++      +Lt+d++e++F
    KIAA2016  1117    VIQELVDTEKSYVKDLSCLFELYLEPLQNET-----FLTQDEMESLF 1158 

                   sNiediyefhreFLkssLearisssnfedlDe....kkiepsaqrlGdlF
                   + +++ +ef++ FL   Le+ is+s   d  + +++  +      lG  F
    KIAA2016  1159 GSLPEMLEFQKVFLE-TLEDGISAS--SDFNTletpSQFRKLLFSLGGSF 1205 

                   lelkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassnt
                   l + a+ +++Y  +c+n+  +q++le+   a++  +F+ fld + +  + 
    KIAA2016  1206 LYY-ADHFKLYSGFCANHIKVQKVLER---AKTDKAFKAFLDARNPTKQH 1251 

                   gAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkk
                            tL+s+L+kPvqR+l+YpLLLkeL++ t+   +s+e+  L +
    KIAA2016  1252 S-------STLESYLIKPVQRVLKYPLLLKELVSLTDQ--ESEEHYHLTE 1292 

                   aldalqdlaksiNe<-*
                   al+a++ +a++iNe   
    KIAA2016  1293 ALKAMEKVASHINE    1306 

PF00621.11.ls: domain 1 of 1, from 1117 to 1306: score 145.9, E = 1e-40
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      v+ El+ TEk Yv+dL  l   y++pL+++      +Lt+d++e++F
    KIAA2016  1117    VIQELVDTEKSYVKDLSCLFELYLEPLQNET-----FLTQDEMESLF 1158 

                   sNiediyefhreFLkssLearisssnfedlDe....kkiepsaqrlGdlF
                   + +++ +ef++ FL   Le+ is+s   d  + +++  +      lG  F
    KIAA2016  1159 GSLPEMLEFQKVFLE-TLEDGISAS--SDFNTletpSQFRKLLFSLGGSF 1205 

                   lelkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassnt
                   l + a+ +++Y  +c+n+  +q++le+   a++  +F+ fld + +  + 
    KIAA2016  1206 LYY-ADHFKLYSGFCANHIKVQKVLER---AKTDKAFKAFLDARNPTKQH 1251 

                   gAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkk
                            tL+s+L+kPvqR+l+YpLLLkeL++ t+   +s+e+  L +
    KIAA2016  1252 S-------STLESYLIKPVQRVLKYPLLLKELVSLTDQ--ESEEHYHLTE 1292 

                   aldalqdlaksiNe<-*
                   al+a++ +a++iNe   
    KIAA2016  1293 ALKAMEKVASHINE    1306 

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