HUGE

Gene/Protein Characteristic Table for KIAA0939

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00690
Accession No. :	AB023156
Description :	Sodium/hydrogen exchanger 8.
HUGO Gene Name :	solute carrier family 9 (sodium/hydrogen exchanger), member 8 (SLC9A8)
Clone Name :	hh04825s1 [Vector Info]
Flexi ORF Clone :	pF1KSDA0939
Source :	Human adult brain
Note :	We replaced hh04825, former representative clones for KIAA0939 with hh04825s1. (2002/5/10)

Features of the cloned DNA sequence	Description

Length: 6087 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 4299 bp

Genome contig ID gi51511747f_47762825
PolyA signal sequence
(AATAAA,-19)
+----*----+----*----+----*----+----
TGGATGCCTATTTAGAAATAAAGTGTATGCTGCTG
Flanking genome sequence
(179356 - 179405)
----+----*----+----*----+----*----+----*----+----*
AATTGGAGCCAGTGTCTGTGTTCATGTTCAGGTGGCTTTGCAGATGCACA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 20 f 47862825 47942179 16 99.3 Perfect prediction

Features of the protein sequence	Description

Length: 595 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
XP_514716	99.5	Na+/H+ exchange...	Pan troglodytes
CAH18432	100.0	hypothetical pr...	Homo sapiens
EAW75648	99.3	solute carrier ...	Homo sapiens
Q9Y2E8	100.0	Sodium/hydrogen...	Homo sapiens
XP_854123	99.0	similar to Na+/...	Canis lupus fam...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
D87743	4.8e-53	36.9	KIAA0267

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR004709 139 150 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 153 167 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 168 176 PR01084 Sodium/hydrogen exchanger subfamily

IPR004709 208 218 PR01084 Sodium/hydrogen exchanger subfamily

HMMPfam IPR006153 76 487 PF00999 Sodium/hydrogen exchanger

HMMTigr IPR004709 67 590 TIGR00840 Sodium/hydrogen exchanger subfamily

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR004709	139	150	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	153	167	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	168	176	PR01084	Sodium/hydrogen exchanger subfamily
IPR004709	208	218	PR01084	Sodium/hydrogen exchanger subfamily
HMMPfam	IPR006153	76	487	PF00999	Sodium/hydrogen exchanger
HMMTigr	IPR004709	67	590	TIGR00840	Sodium/hydrogen exchanger subfamily

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 30 HEGFNVTLHTTLVVTTKLVLPTP 52 SECONDARY 23

2 74 MTIFFSLLVLAICIILVHLLIR 95 PRIMARY 22

3 102 PESVAVVSLGILMGAVIKIIEF 123 PRIMARY 22

4 166 GSITLFAVFGTAISAFVVGGGIY 188 PRIMARY 23

5 201 MTDSFAFGSLISAVDPVATIAIF 223 SECONDARY 23

6 278 FLKMFFGSAALGTLTGLISALVL 300 SECONDARY 23

7 328 EGISLSGIMAILFSGIVMSHYTH 350 PRIMARY 23

8 366 RTVAFLCETCVFAFLGLSIFSFP 388 PRIMARY 23

9 395 FVIWCIVLVLFGRAVNIFPLSYL 417 PRIMARY 23

10 465 TTIVIVLFTILLLGGSTMPLIRL 487 SECONDARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	30	HEGFNVTLHTTLVVTTKLVLPTP	52	SECONDARY	23
2	74	MTIFFSLLVLAICIILVHLLIR	95	PRIMARY	22
3	102	PESVAVVSLGILMGAVIKIIEF	123	PRIMARY	22
4	166	GSITLFAVFGTAISAFVVGGGIY	188	PRIMARY	23
5	201	MTDSFAFGSLISAVDPVATIAIF	223	SECONDARY	23
6	278	FLKMFFGSAALGTLTGLISALVL	300	SECONDARY	23
7	328	EGISLSGIMAILFSGIVMSHYTH	350	PRIMARY	23
8	366	RTVAFLCETCVFAFLGLSIFSFP	388	PRIMARY	23
9	395	FVIWCIVLVLFGRAVNIFPLSYL	417	PRIMARY	23
10	465	TTIVIVLFTILLLGGSTMPLIRL	487	SECONDARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GTAAAAATGACGAGTGCTGGG

Primer_r
: CCAAGAAGAGCAGCACATCAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 20

Experimental conditions

Panel name	: UniGene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	4299 bp
Genome contig ID	gi51511747f_47762825
PolyA signal sequence (AATAAA,-19)	+--------+--------+----*----+---- TGGATGCCTATTTAGAAATAAAGTGTATGCTGCTG
Flanking genome sequence (179356 - 179405)	----+--------+--------+--------+--------+----* AATTGGAGCCAGTGTCTGTGTTCATGTTCAGGTGGCTTTGCAGATGCACA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	20	f	47862825	47942179	16	99.3	Perfect prediction

Primer_f	: GTAAAAATGACGAGTGCTGGG
Primer_r	: CCAAGAAGAGCAGCACATCAC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA0939

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information