HUGE

Gene/Protein Characteristic Table for KIAA1054

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK07033
Accession No. :	AB028977
Description :	Synaptic vesicle glycoprotein 2C.
HUGO Gene Name :
Clone Name :	hh05240 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 5962 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 4517 bp

Genome contig ID gi51511721f_75441316
PolyA signal sequence
(AGTAAA,-33)
+----*----+----*----+----*----+----
TAAGTAAAGCTTCTCTTGTTATCTGTAATGTAGAC
Flanking genome sequence
(220331 - 220380)
----+----*----+----*----+----*----+----*----+----*
AAAAAAAAAAAAAAACCTGTTAGTATATTCTGGATGTATTGTGTGTCCCT

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 5 f 75526659 75661645 11 99.2 Perfect prediction

Features of the protein sequence	Description

Length: 480 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
Q496J9	7.9e-206	100.0	Synaptic vesicl...	Homo sapiens
EAW95772	3.1e-205	99.6	synaptic vesicl...	Homo sapiens
AAI00825	4.2e-205	99.8	Synaptic vesicl...	Homo sapiens
XP_526889	1.8e-203	99.2	synaptic vesicl...	Pan troglodytes
XP_001105846	3.3e-203	99.0	similar to syna...	Macaca mulatta

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB018279	5.7e-148	64.2	KIAA0736
AB018278	3.6e-146	62.3	KIAA0735

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR005828 1 114 PF00083 General substrate transporter

IPR011701 330 447 PF07690 Major facilitator superfamily MFS_1

HMMTigr IPR005988 1 480 TIGR01299 Synaptic vesicle protein SV2

ProfileScan IPR007114 1 475 PS50850 Major facilitator superfamily

ScanRegExp IPR005829 3 28 PS00217 Sugar transporter superfamily

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR005828	1	114	PF00083	General substrate transporter
IPR011701	330	447	PF07690	Major facilitator superfamily MFS_1
HMMTigr	IPR005988	1	480	TIGR01299	Synaptic vesicle protein SV2
ProfileScan	IPR007114	1	475	PS50850	Major facilitator superfamily
ScanRegExp	IPR005829	3	28	PS00217	Sugar transporter superfamily

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 2 LLSGFGIGGAIPTVFSYFAEVLA 24 SECONDARY 23

2 33 SWLCMFWMIGGIYASAMAWAIIP 55 PRIMARY 23

3 70 HSWRVFVIVCALPCVSSVVALTF 92 PRIMARY 23

4 334 WIYFVNFLGTLAVLPGNIVSALL 356 PRIMARY 23

5 362 RLTMLGGSMVLSGISCFFLWFG 383 PRIMARY 22

6 386 ESMMIGMLCLYNGLTISAWNSLD 408 SECONDARY 23

7 423 GFGFLNALCKAAAVLGNLIFGSL 445 SECONDARY 23

8 455 LLASTVLVCGGLVGLCLPDTRTQ 477 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	2	LLSGFGIGGAIPTVFSYFAEVLA	24	SECONDARY	23
2	33	SWLCMFWMIGGIYASAMAWAIIP	55	PRIMARY	23
3	70	HSWRVFVIVCALPCVSSVVALTF	92	PRIMARY	23
4	334	WIYFVNFLGTLAVLPGNIVSALL	356	PRIMARY	23
5	362	RLTMLGGSMVLSGISCFFLWFG	383	PRIMARY	22
6	386	ESMMIGMLCLYNGLTISAWNSLD	408	SECONDARY	23
7	423	GFGFLNALCKAAAVLGNLIFGSL	445	SECONDARY	23
8	455	LLASTVLVCGGLVGLCLPDTRTQ	477	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GTCATTTCCAAAGCAGTCCAG

Primer_r
: GAGCCTTTAGTGCATGAACAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 5

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: GTCATTTCCAAAGCAGTCCAG
Primer_r	: GAGCCTTTAGTGCATGAACAG
PCR product length	: 159 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	4517 bp
Genome contig ID	gi51511721f_75441316
PolyA signal sequence (AGTAAA,-33)	+--------+--------+----*----+---- TAAGTAAAGCTTCTCTTGTTATCTGTAATGTAGAC
Flanking genome sequence (220331 - 220380)	----+--------+--------+--------+--------+----* AAAAAAAAAAAAAAACCTGTTAGTATATTCTGGATGTATTGTGTGTCCCT

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	5	f	75526659	75661645	11	99.2	Perfect prediction

Gene/Protein Characteristic Table for KIAA1054

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information