HUGE

Gene/Protein Characteristic Table for KIAA1133

Link to : GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00746
Accession No. :	AB051436
Description :	Zinc/RING finger protein 3 precursor.
HUGO Gene Name :	zinc and ring finger 3 (ZNRF3)
Clone Name :	hg03758b [Vector Info]
Flexi ORF Clone :	pF1KSDA1133
Source :	Human adult brain
Note :	We replaced hh04035, former representative clones for KIAA1133 with hg03758b. (2001/5/29)

Features of the cloned DNA sequence	Description

Length: 6542 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 3866 bp

Genome contig ID gi89161203f_27509890
PolyA signal sequence
(AATACA,-25)
+----*----+----*----+----*----+----
GTAAAAAAAAAATACAATTTTATCAAGTATGTGTT
Flanking genome sequence
(273587 - 273636)
----+----*----+----*----+----*----+----*----+----*
ATATGTTGTCATTGGTCTGTTCAGTAAAAGTCTGCAGATTCAACAAGGGG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 22 f 27609890 27783475 9 99.1 Perfect prediction

Features of the protein sequence	Description

Length: 891 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q9ULT6	100.0	Zinc/RING finge...	Homo sapiens
CAG30283	100.0	bK175E3.6 [Homo...	Homo sapiens
BAG53280	99.8	unnamed protein...	Homo sapiens
XP_515054	99.4	zinc and ring f...	Pan troglodytes
XP_001499538	89.6	similar to Zinc...	Equus caballus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB033040	5.6e-05	26.1	KIAA1214

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001841 248 288 PF00097 Zinc finger

HMMSmart IPR001841 248 288 SM00184 Zinc finger

ProfileScan IPR001841 248 289 PS50089 Zinc finger

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001841	248	288	PF00097	Zinc finger
HMMSmart	IPR001841	248	288	SM00184	Zinc finger
ProfileScan	IPR001841	248	289	PS50089	Zinc finger

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 173 DMGIFLAFFVVVSLVCLILLVK 194 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	173	DMGIFLAFFVVVSLVCLILLVK	194	PRIMARY	22

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: ACAGCCATATACAGTGAAGAG

Primer_r
: TAAGTATGTGAGCAGTGGGAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 22

Experimental conditions

Panel name	: unigene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	3866 bp
Genome contig ID	gi89161203f_27509890
PolyA signal sequence (AATACA,-25)	+--------+--------+----*----+---- GTAAAAAAAAAATACAATTTTATCAAGTATGTGTT
Flanking genome sequence (273587 - 273636)	----+--------+--------+--------+--------+----* ATATGTTGTCATTGGTCTGTTCAGTAAAAGTCTGCAGATTCAACAAGGGG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	22	f	27609890	27783475	9	99.1	Perfect prediction

Primer_f	: ACAGCCATATACAGTGAAGAG
Primer_r	: TAAGTATGTGAGCAGTGGGAC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1133

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information