HUGE

Gene/Protein Characteristic Table for KIAA1337

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00806
Accession No. :	AB037758
Description :	patched domain containing 2.
HUGO Gene Name :	patched domain containing 2 (PTCHD2)
Clone Name :	fh16696 [Vector Info]
Flexi ORF Clone :	pF1KSDA1337
Source :	Human fetal brain

Features of the cloned DNA sequence	Description

Length: 5181 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 864 bp

Genome contig ID gi89161185f_11361882
PolyA signal sequence
(ATTAAA,-21)
+----*----+----*----+----*----+----
GGCAGAAGGTTGCTATTAAAATGACATAGGATTGC
Flanking genome sequence
(158314 - 158363)
----+----*----+----*----+----*----+----*----+----*
AGACTGCTGCTGTTAATACGAGCATTTTAAGCACTGCTGTCTCTACCGCT

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 1 f 11461882 11520194 21 99.8 Perfect prediction

Features of the protein sequence	Description

Length: 1438 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
CAH70606	99.9	patched domain ...	Homo sapiens
BAG10036	100.0	patched domain-...	synthetic construct
Q9P2K9	99.9	Patched domain-...	Homo sapiens
XP_001915151	92.7	patched domain ...	Equus caballus
XP_873073	91.1	similar to patc...	Bos taurus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB051529	5.8e-05	31.2	KIAA1742

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR003392 285 1392 PF02460 Patched

ProfileScan IPR000731 556 661 PS50156 Sterol-sensing 5TM box

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR003392	285	1392	PF02460	Patched
ProfileScan	IPR000731	556	661	PS50156	Sterol-sensing 5TM box

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 118 CCAGLVLFLGCSIPMALSAFMFL 140 PRIMARY 23

2 506 NNDMLLAFISSSCIAALVYILTS 528 PRIMARY 23

3 536 FGIASIGLSCLVALFLYHVVFGI 558 PRIMARY 23

4 565 NGVAAFVIVGIGVDDVFVFINTY 587 PRIMARY 23

5 611 TFFTSLTTAAAYAANVFSQIPAV 633 SECONDARY 23

6 642 LIVSCCWLAVLVTMPAALGLWSL 664 PRIMARY 23

7 775 RWVIVGLFVSILILSLVFASR 795 PRIMARY 21

8 932 ACMSTVGLLQAASPSRKWMLTTL 954 SECONDARY 23

9 1047 VRPLVDTGAMVFVVFGIIGVNR 1068 PRIMARY 22

10 1220 FMEIVGVQSALCGLVLSLLICVA 1242 PRIMARY 23

11 1251 ILLLLPVLLSILGIVCLVVTIMY 1273 PRIMARY 23

12 1285 ISLSILVGSSVDYCVHLVEGYLL 1307 SECONDARY 23

13 1334 HVGVAIVSSALTTVIATVPLFFC 1356 PRIMARY 23

14 1370 LNTGVSILYTLTVSTALLGIMAP 1392 SECONDARY 23

15 1403 LKALGAVLLAGALGLGACLVLLQ 1425 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	118	CCAGLVLFLGCSIPMALSAFMFL	140	PRIMARY	23
2	506	NNDMLLAFISSSCIAALVYILTS	528	PRIMARY	23
3	536	FGIASIGLSCLVALFLYHVVFGI	558	PRIMARY	23
4	565	NGVAAFVIVGIGVDDVFVFINTY	587	PRIMARY	23
5	611	TFFTSLTTAAAYAANVFSQIPAV	633	SECONDARY	23
6	642	LIVSCCWLAVLVTMPAALGLWSL	664	PRIMARY	23
7	775	RWVIVGLFVSILILSLVFASR	795	PRIMARY	21
8	932	ACMSTVGLLQAASPSRKWMLTTL	954	SECONDARY	23
9	1047	VRPLVDTGAMVFVVFGIIGVNR	1068	PRIMARY	22
10	1220	FMEIVGVQSALCGLVLSLLICVA	1242	PRIMARY	23
11	1251	ILLLLPVLLSILGIVCLVVTIMY	1273	PRIMARY	23
12	1285	ISLSILVGSSVDYCVHLVEGYLL	1307	SECONDARY	23
13	1334	HVGVAIVSSALTTVIATVPLFFC	1356	PRIMARY	23
14	1370	LNTGVSILYTLTVSTALLGIMAP	1392	SECONDARY	23
15	1403	LKALGAVLLAGALGLGACLVLLQ	1425	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: TGTGGTCTTCGGCATTATTGG

Primer_r
: AGGTCAAAGCTGCTGTCGTAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 1

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TGTGGTCTTCGGCATTATTGG
Primer_r	: AGGTCAAAGCTGCTGTCGTAG
PCR product length	: 99(1.0k) bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	864 bp
Genome contig ID	gi89161185f_11361882
PolyA signal sequence (ATTAAA,-21)	+--------+--------+----*----+---- GGCAGAAGGTTGCTATTAAAATGACATAGGATTGC
Flanking genome sequence (158314 - 158363)	----+--------+--------+--------+--------+----* AGACTGCTGCTGTTAATACGAGCATTTTAAGCACTGCTGTCTCTACCGCT

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	1	f	11461882	11520194	21	99.8	Perfect prediction

Gene/Protein Characteristic Table for KIAA1337

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information