FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0001, 338 aa 1>>>pF1KA0001 338 - 338 aa - 338 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7223+/-0.000533; mu= 14.1058+/- 0.033 mean_var=164.8985+/-45.549, 0's: 0 Z-trim(108.5): 497 B-trim: 1001 in 1/52 Lambda= 0.099877 statistics sampled from 15899 (16563) to 15899 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.194), width: 16 Scan time: 7.090 The best scores are: opt bits E(85289) XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 2210 331.6 1.5e-90 NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo ( 338) 2210 331.6 1.5e-90 XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 2210 331.6 1.5e-90 XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 2210 331.6 1.5e-90 NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [H ( 338) 2210 331.6 1.5e-90 XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinoc ( 338) 2210 331.6 1.5e-90 NP_795713 (OMIM: 606380) P2Y purinoceptor 13 [Homo ( 354) 1028 161.3 2.8e-39 NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 1001 157.4 4.1e-38 NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 1 ( 342) 1001 157.4 4.1e-38 XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y ( 342) 1001 157.4 4.1e-38 NP_076404 (OMIM: 606379) G-protein coupled recepto ( 358) 999 157.1 5.1e-38 NP_005291 (OMIM: 300241) probable G-protein couple ( 381) 645 106.2 1.2e-22 NP_001091048 (OMIM: 300241) probable G-protein cou ( 381) 645 106.2 1.2e-22 XP_005272654 (OMIM: 300241) PREDICTED: probable G- ( 381) 645 106.2 1.2e-22 XP_006713727 (OMIM: 606380) PREDICTED: P2Y purinoc ( 224) 632 104.0 3.2e-22 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 494 84.4 4e-16 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 494 84.4 4e-16 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 494 84.4 4e-16 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 494 84.4 4e-16 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 474 81.5 2.9e-15 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 474 81.5 2.9e-15 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 474 81.5 3.1e-15 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 474 81.5 3.1e-15 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 474 81.5 3.1e-15 XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 469 80.8 5e-15 NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 469 80.8 5e-15 NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 453 78.4 2.4e-14 NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 453 78.4 2.4e-14 NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 453 78.4 2.4e-14 NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 453 78.4 2.4e-14 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 447 77.6 4.4e-14 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 447 77.6 4.4e-14 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 447 77.6 4.4e-14 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 439 76.5 1e-13 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 439 76.5 1e-13 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 439 76.5 1e-13 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 439 76.5 1e-13 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 439 76.5 1e-13 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 439 76.5 1e-13 NP_065133 (OMIM: 606926) lysophosphatidic acid rec ( 372) 431 75.3 2.3e-13 NP_001136433 (OMIM: 606926) lysophosphatidic acid ( 372) 431 75.3 2.3e-13 NP_001295397 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295399 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295394 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295400 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295396 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295398 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_001295405 (OMIM: 605666) cysteinyl leukotriene ( 346) 429 75.0 2.6e-13 NP_065110 (OMIM: 605666) cysteinyl leukotriene rec ( 346) 429 75.0 2.6e-13 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 427 74.7 3.4e-13 >>XP_016863072 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: XP_016 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>NP_055694 (OMIM: 610116) P2Y purinoceptor 14 [Homo sap (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: NP_055 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>XP_005247980 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: XP_005 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>XP_005247979 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: XP_005 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>NP_001074924 (OMIM: 610116) P2Y purinoceptor 14 [Homo (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: NP_001 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>XP_011511642 (OMIM: 610116) PREDICTED: P2Y purinocepto (338 aa) initn: 2210 init1: 2210 opt: 2210 Z-score: 1746.9 bits: 331.6 E(85289): 1.5e-90 Smith-Waterman score: 2210; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KA0 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ 250 260 270 280 290 300 310 320 330 pF1KA0 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL :::::::::::::::::::::::::::::::::::::: XP_011 PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL 310 320 330 >>NP_795713 (OMIM: 606380) P2Y purinoceptor 13 [Homo sap (354 aa) initn: 1006 init1: 985 opt: 1028 Z-score: 826.2 bits: 161.3 E(85289): 2.8e-39 Smith-Waterman score: 1028; 46.6% identity (78.6% similar) in 309 aa overlap (2-307:22-330) 10 20 30 pF1KA0 MINSTSTQPPDES--CSQNLLITQQIIPVLYCMVFIAGIL .:.: : ..: : .. :.: ..:.:: .::..::: NP_795 MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGIL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 LNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSA :: .. :.: ..:::..::::::: ..::..:.: .:::::.:: :.:::: .:::: :. NP_795 LNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSS 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 VLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNII :.:: .:::.::..:::.:::. ::..:: . :... ..: .:...:........:: : NP_795 VIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTI 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 LTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHL :.:. . . :: ::. :: :::. : : ::: ::.:..:::..:.::.. :. NP_795 LSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 KSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKE ::. .. . .:: ..: .: ::::::.:.:.::.:::.:::. . .:. .. : :: NP_795 KSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKE 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 FTLLLSAANVCLDPIIYFFLCQPFREIL-CKKLHIPLKAQNDLDISRIKRGNTTLESTDT ::.:.:.:.:.::.::.:::. : : : : NP_795 TTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG 310 320 330 340 350 >>NP_073625 (OMIM: 600515,609821) P2Y purinoceptor 12 [H (342 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 805.3 bits: 157.4 E(85289): 4.1e-38 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (2-316:4-319) 10 20 30 40 50 pF1KA0 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: NP_073 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. NP_073 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: NP_073 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: NP_073 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: NP_073 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 300 310 320 330 pF1KA0 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL ::. ::. : . :. : .: NP_073 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 >>NP_795345 (OMIM: 600515,609821) P2Y purinoceptor 12 [H (342 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 805.3 bits: 157.4 E(85289): 4.1e-38 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (2-316:4-319) 10 20 30 40 50 pF1KA0 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: NP_795 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. NP_795 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: NP_795 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: NP_795 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: NP_795 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 300 310 320 330 pF1KA0 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL ::. ::. : . :. : .: NP_795 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 >>XP_016862558 (OMIM: 600515,609821) PREDICTED: P2Y puri (342 aa) initn: 1023 init1: 990 opt: 1001 Z-score: 805.3 bits: 157.4 E(85289): 4.1e-38 Smith-Waterman score: 1001; 46.8% identity (77.5% similar) in 316 aa overlap (2-316:4-319) 10 20 30 40 50 pF1KA0 MINSTSTQPPDES-CSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFI ... .. : . : :... ::: ..:.:: ..:..:.. ::.. ::: . :...:: XP_016 MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 IYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISF :.::: ::.:..: ::::::::.:. :: : .:::.:..:.:: .::.:: :.:::.. XP_016 IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 DRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKS ::: : ..:. :: ... .:.:::..: .:.::..::.::::.. :. . :: ::: XP_016 DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 ELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFS :.: ::. ::: .:::: ::..:: :: :::....:.... . .:: . ..: XP_016 EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 IVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFF :. :::.::::.:.:::::: :::. ..: ... : :.:: :: :.. :.::::.:::: XP_016 IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF 250 260 270 280 290 300 300 310 320 330 pF1KA0 LCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL ::. ::. : . :. : .: XP_016 LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM 310 320 330 340 338 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 17:52:27 2016 done: Wed Nov 2 17:52:28 2016 Total Scan time: 7.090 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]