FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0012, 786 aa 1>>>pF1KA0012 786 - 786 aa - 786 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0349+/-0.000645; mu= 11.6719+/- 0.039 mean_var=143.4169+/-30.979, 0's: 0 Z-trim(107.6): 285 B-trim: 680 in 1/52 Lambda= 0.107096 statistics sampled from 15353 (15686) to 15353 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.519), E-opt: 0.2 (0.184), width: 16 Scan time: 8.240 The best scores are: opt bits E(85289) NP_003254 (OMIM: 601194,613223) toll-like receptor ( 786) 5165 811.5 0 XP_011512046 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_011512047 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_005262719 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_016864060 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_011512044 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_011512045 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_016864061 (OMIM: 601194,613223) PREDICTED: toll ( 786) 5165 811.5 0 XP_011511914 (OMIM: 605403) PREDICTED: toll-like r ( 796) 3630 574.3 6.9e-163 XP_005262694 (OMIM: 605403) PREDICTED: toll-like r ( 796) 3630 574.3 6.9e-163 XP_011511916 (OMIM: 605403) PREDICTED: toll-like r ( 796) 3630 574.3 6.9e-163 XP_011511915 (OMIM: 605403) PREDICTED: toll-like r ( 796) 3630 574.3 6.9e-163 NP_006059 (OMIM: 605403) toll-like receptor 6 prec ( 796) 3630 574.3 6.9e-163 NP_001182036 (OMIM: 606270) toll-like receptor 10 ( 811) 2509 401.1 9.6e-111 XP_011512063 (OMIM: 606270) PREDICTED: toll-like r ( 811) 2509 401.1 9.6e-111 NP_001182035 (OMIM: 606270) toll-like receptor 10 ( 811) 2509 401.1 9.6e-111 NP_112218 (OMIM: 606270) toll-like receptor 10 iso ( 811) 2509 401.1 9.6e-111 NP_001017388 (OMIM: 606270) toll-like receptor 10 ( 811) 2509 401.1 9.6e-111 XP_011512064 (OMIM: 606270) PREDICTED: toll-like r ( 811) 2509 401.1 9.6e-111 XP_011512062 (OMIM: 606270) PREDICTED: toll-like r ( 797) 2503 400.2 1.8e-110 NP_001182037 (OMIM: 606270) toll-like receptor 10 ( 797) 2503 400.2 1.8e-110 NP_001305724 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 NP_001305725 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 NP_001305716 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 XP_016864063 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 XP_016864062 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 NP_003255 (OMIM: 246300,603028,607948) toll-like r ( 784) 1183 196.2 4.4e-49 NP_001305719 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 XP_011530518 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 NP_001305718 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 NP_001305720 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 NP_001305722 (OMIM: 246300,603028,607948) toll-lik ( 784) 1183 196.2 4.4e-49 XP_016864064 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 XP_016864065 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 XP_011530517 (OMIM: 246300,603028,607948) PREDICTE ( 784) 1183 196.2 4.4e-49 NP_619542 (OMIM: 300366) toll-like receptor 8 isof (1041) 514 93.0 7.1e-18 NP_057694 (OMIM: 300366) toll-like receptor 8 isof (1059) 514 93.0 7.2e-18 XP_011543832 (OMIM: 300366) PREDICTED: toll-like r (1059) 514 93.0 7.2e-18 XP_011543831 (OMIM: 300366) PREDICTED: toll-like r (1059) 514 93.0 7.2e-18 XP_011508239 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_005273298 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 NP_003259 (OMIM: 601744,603031,608556,615557) toll ( 858) 454 83.6 3.8e-15 XP_006711569 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_005273299 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_006711567 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_006711568 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_005273300 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 XP_016857697 (OMIM: 601744,603031,608556,615557) P ( 858) 454 83.6 3.8e-15 NP_003257 (OMIM: 603030,611488) toll-like receptor ( 799) 410 76.8 4e-13 NP_612564 (OMIM: 603030,611488) toll-like receptor ( 839) 410 76.8 4.2e-13 >>NP_003254 (OMIM: 601194,613223) toll-like receptor 1 p (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_003 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: NP_003 TEQAKK >>XP_011512046 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_011 TEQAKK >>XP_011512047 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_011 TEQAKK >>XP_005262719 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_005 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_005 TEQAKK >>XP_016864060 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_016 TEQAKK >>XP_011512044 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_011 TEQAKK >>XP_011512045 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_011 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_011 TEQAKK >>XP_016864061 (OMIM: 601194,613223) PREDICTED: toll-lik (786 aa) initn: 5165 init1: 5165 opt: 5165 Z-score: 4327.2 bits: 811.5 E(85289): 0 Smith-Waterman score: 5165; 99.9% identity (99.9% similar) in 786 aa overlap (1-786:1-786) 10 20 30 40 50 60 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 WTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 WTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNKLVKISCHPTVNLKHLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYFLSILAKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHLDFSNNLL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDEKKGDCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQELNVAFNSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELGEFVKNID 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVLAVTVTSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKNELLPNLE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLRAAINIKL 730 740 750 760 770 780 pF1KA0 TEQAKK :::::: XP_016 TEQAKK >>XP_011511914 (OMIM: 605403) PREDICTED: toll-like recep (796 aa) initn: 3630 init1: 2821 opt: 3630 Z-score: 3045.4 bits: 574.3 E(85289): 6.9e-163 Smith-Waterman score: 3630; 69.4% identity (88.0% similar) in 777 aa overlap (5-781:12-786) 10 20 30 40 50 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNIS :::. ....:. :::.:. .:: ::.:: ::::::::: :: .:..: XP_011 MTKDKEPIVKSFHFVCLMIIIVGTRIQFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 QNYISELWTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPT ::::.:: .::. ::.: .: .::: :: ::.:::::::.:::::::::.: :::::: XP_011 QNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKISCHPI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 VNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGE :...::::::: : ::::::::::.:::.:::::. .:.: ..::::::..: .:: : . XP_011 VSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLSYILLDLRN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 TYGEKEDPEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYF : .... :.:: .:...::.:: .. : . ...::.:.. :.:.::: :.:..:. : XP_011 YYIKENETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIK--LNDDNCQVF 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 LSILAKLQTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFD ...:..: . : :.:::.:::::. ..:..:..: : :..: :. . .. .:: XP_011 IKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 YSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHL :: :.::::.:......:: : :. .: .::.::: .:.: : ..::::: : : : XP_011 YSKTTLKALTIEHITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 DFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYD .:..:..::..::.:. :..::::::: : ::.: :.. :: .: ::. ::.: ::. XP_011 NFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESG 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 EKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQEL ..: .:.:..:.. ::.:::.:::..::::::::::::::::::::.::::::::::::: XP_011 RHKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQEL 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 NVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 EFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVL :::::::::::::::::::::::::::::::. :::::::::::::::::::: :::::: XP_011 EFVKNIDQVSSEVLEGWPDSYKCDYPESYRGSPLKDFHMSELSCNITLLIVTIGATMLVL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 AVTVTSLCSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKN :::::::: :::::::::::::::::::::::::::::::::::::::::: ::: :::. XP_011 AVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKS 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 ELLPNLEKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYF ::.: :::: .::::::::::::::::::::.:::::::::::::::::::::::::::: XP_011 ELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 AHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLR :::::::::::.::::::::::: :::..:::::.::..::::.::::::::::::::.: XP_011 AHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANIR 720 730 740 750 760 770 780 pF1KA0 AAINIKLTEQAKK ::.:.::: XP_011 AAFNMKLTLVTENNDVKS 780 790 >>XP_005262694 (OMIM: 605403) PREDICTED: toll-like recep (796 aa) initn: 3630 init1: 2821 opt: 3630 Z-score: 3045.4 bits: 574.3 E(85289): 6.9e-163 Smith-Waterman score: 3630; 69.4% identity (88.0% similar) in 777 aa overlap (5-781:12-786) 10 20 30 40 50 pF1KA0 MTSIFHFAIIFMLILQIRIQLSEESEFLVDRSKNGLIHVPKDLSQKTTILNIS :::. ....:. :::.:. .:: ::.:: ::::::::: :: .:..: XP_005 MTKDKEPIVKSFHFVCLMIIIVGTRIQFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 QNYISELWTSDILSLSKLRILIISHNTIQYLDISVFKFNQELEYLDLSHNKLVKISCHPT ::::.:: .::. ::.: .: .::: :: ::.:::::::.:::::::::.: :::::: XP_005 QNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKISCHPI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 VNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGE :...::::::: : ::::::::::.:::.:::::. .:.: ..::::::..: .:: : . XP_005 VSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLSYILLDLRN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 TYGEKEDPEGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCVLEDNKCSYF : .... :.:: .:...::.:: .. : . ...::.:.. :.:.::: :.:..:. : XP_005 YYIKENETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIK--LNDDNCQVF 190 200 210 220 230 240 250 260 270 280 290 pF1KA0 LSILAKLQTNPKLSNLTLNNIETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFD ...:..: . : :.:::.:::::. ..:..:..: : :..: :. . .. .:: XP_005 IKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA0 YSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTRMVHMLCPSKISPFLHL :: :.::::.:......:: : :. .: .::.::: .:.: : ..::::: : : : XP_005 YSKTTLKALTIEHITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 DFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYD .:..:..::..::.:. :..::::::: : ::.: :.. :: .: ::. ::.: ::. XP_005 NFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESG 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 EKKGDCSWTKSLLSLNMSSNILTDTIFRCLPPRIKVLDLHSNKIKSIPKQVVKLEALQEL ..: .:.:..:.. ::.:::.:::..::::::::::::::::::::.::::::::::::: XP_005 RHKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQEL 420 430 440 450 460 470 480 490 500 510 520 530 pF1KA0 NVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KA0 EFVKNIDQVSSEVLEGWPDSYKCDYPESYRGTLLKDFHMSELSCNITLLIVTIVATMLVL :::::::::::::::::::::::::::::::. :::::::::::::::::::: :::::: XP_005 EFVKNIDQVSSEVLEGWPDSYKCDYPESYRGSPLKDFHMSELSCNITLLIVTIGATMLVL 540 550 560 570 580 590 600 610 620 630 640 650 pF1KA0 AVTVTSLCSYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSGHDSFWVKN :::::::: :::::::::::::::::::::::::::::::::::::::::: ::: :::. XP_005 AVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKS 600 610 620 630 640 650 660 670 680 690 700 710 pF1KA0 ELLPNLEKEGMQICLHERNFVPGKSIVENIITCIEKSYKSIFVLSPNFVQSEWCHYELYF ::.: :::: .::::::::::::::::::::.:::::::::::::::::::::::::::: XP_005 ELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYF 660 670 680 690 700 710 720 730 740 750 760 770 pF1KA0 AHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMARRTYLEWPKEKSKRGLFWANLR :::::::::::.::::::::::: :::..:::::.::..::::.::::::::::::::.: XP_005 AHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANIR 720 730 740 750 760 770 780 pF1KA0 AAINIKLTEQAKK ::.:.::: XP_005 AAFNMKLTLVTENNDVKS 780 790 786 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:20:23 2016 done: Fri Nov 4 00:20:25 2016 Total Scan time: 8.240 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]