FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0013, 1023 aa 1>>>pF1KA0013 1023 - 1023 aa - 1023 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5757+/-0.00123; mu= 10.5211+/- 0.073 mean_var=120.8982+/-24.090, 0's: 0 Z-trim(104.1): 118 B-trim: 0 in 0/50 Lambda= 0.116644 statistics sampled from 7589 (7709) to 7589 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.237), width: 16 Scan time: 4.120 The best scores are: opt bits E(32554) CCDS10028.1 ARHGAP11A gene_id:9824|Hs108|chr15 (1023) 6690 1138.1 0 CCDS66730.1 ARHGAP11A gene_id:9824|Hs108|chr15 ( 834) 5422 924.7 0 CCDS58349.1 ARHGAP11A gene_id:9824|Hs108|chr15 ( 501) 3258 560.4 3.2e-159 CCDS32185.1 ARHGAP11B gene_id:89839|Hs108|chr15 ( 267) 1440 254.4 2.3e-67 >>CCDS10028.1 ARHGAP11A gene_id:9824|Hs108|chr15 (1023 aa) initn: 6690 init1: 6690 opt: 6690 Z-score: 6088.3 bits: 1138.1 E(32554): 0 Smith-Waterman score: 6690; 100.0% identity (100.0% similar) in 1023 aa overlap (1-1023:1-1023) 10 20 30 40 50 60 pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP 970 980 990 1000 1010 1020 pF1KA0 VDL ::: CCDS10 VDL >>CCDS66730.1 ARHGAP11A gene_id:9824|Hs108|chr15 (834 aa) initn: 5422 init1: 5422 opt: 5422 Z-score: 4936.5 bits: 924.7 E(32554): 0 Smith-Waterman score: 5422; 100.0% identity (100.0% similar) in 834 aa overlap (190-1023:1-834) 160 170 180 190 200 210 pF1KA0 SCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEK :::::::::::::::::::::::::::::: CCDS66 MDSSNLAVIFAPNLLQTSEGHEKMSSNTEK 10 20 30 220 230 240 250 260 270 pF1KA0 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK 40 50 60 70 80 90 280 290 300 310 320 330 pF1KA0 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS 100 110 120 130 140 150 340 350 360 370 380 390 pF1KA0 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP 160 170 180 190 200 210 400 410 420 430 440 450 pF1KA0 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES 220 230 240 250 260 270 460 470 480 490 500 510 pF1KA0 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM 280 290 300 310 320 330 520 530 540 550 560 570 pF1KA0 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI 340 350 360 370 380 390 580 590 600 610 620 630 pF1KA0 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP 400 410 420 430 440 450 640 650 660 670 680 690 pF1KA0 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH 460 470 480 490 500 510 700 710 720 730 740 750 pF1KA0 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA 520 530 540 550 560 570 760 770 780 790 800 810 pF1KA0 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL 580 590 600 610 620 630 820 830 840 850 860 870 pF1KA0 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA 640 650 660 670 680 690 880 890 900 910 920 930 pF1KA0 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN 700 710 720 730 740 750 940 950 960 970 980 990 pF1KA0 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA 760 770 780 790 800 810 1000 1010 1020 pF1KA0 WYKGSPKHPIGKTQLLPTSKPVDL :::::::::::::::::::::::: CCDS66 WYKGSPKHPIGKTQLLPTSKPVDL 820 830 >>CCDS58349.1 ARHGAP11A gene_id:9824|Hs108|chr15 (501 aa) initn: 3258 init1: 3258 opt: 3258 Z-score: 2971.9 bits: 560.4 E(32554): 3.2e-159 Smith-Waterman score: 3258; 99.8% identity (100.0% similar) in 496 aa overlap (1-496:1-496) 10 20 30 40 50 60 pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM :::::::::::::::. CCDS58 LLFSPDVDEKLPKKGTFTYYC 490 500 >>CCDS32185.1 ARHGAP11B gene_id:89839|Hs108|chr15 (267 aa) initn: 1439 init1: 1439 opt: 1440 Z-score: 1322.8 bits: 254.4 E(32554): 2.3e-67 Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-231:1-226) 10 20 30 40 50 60 pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: CCDS32 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: CCDS32 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR ::::::::::::::::::::::::::::::::::::.::: .: ::: CCDS32 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN CCDS32 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV 240 250 260 1023 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:21:07 2016 done: Fri Nov 4 00:21:08 2016 Total Scan time: 4.120 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]