Result of FASTA (omim) for
pF1KA0013
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0013, 1023 aa
1>>>pF1KA0013 1023 - 1023 aa - 1023 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1908+/-0.00052; mu= 13.0586+/- 0.032
mean_var=155.6699+/-31.847, 0's: 0 Z-trim(111.6): 360 B-trim: 193 in 1/53
Lambda= 0.102795
statistics sampled from 19878 (20266) to 19878 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.238), width: 16
Scan time: 14.350
The best scores are: opt bits E(85289)
NP_055598 (OMIM: 610589) rho GTPase-activating pro (1023) 6690 1005.7 0
NP_001273408 (OMIM: 610589) rho GTPase-activating ( 834) 5422 817.6 0
NP_001273409 (OMIM: 610589) rho GTPase-activating ( 834) 5422 817.6 0
NP_955389 (OMIM: 610589) rho GTPase-activating pro ( 501) 3258 496.5 1.5e-139
NP_001034930 (OMIM: 616310) rho GTPase-activating ( 267) 1440 226.6 1.4e-58
XP_016871965 (OMIM: 610585) PREDICTED: rho GTPase- ( 414) 292 56.5 3.4e-07
XP_016871962 (OMIM: 610585) PREDICTED: rho GTPase- ( 420) 292 56.5 3.5e-07
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 290 56.2 3.8e-07
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 290 56.3 4.4e-07
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 292 56.7 4.6e-07
XP_005267270 (OMIM: 613351) PREDICTED: rho GTPase- ( 585) 291 56.5 4.9e-07
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 292 56.7 5.1e-07
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 292 56.7 5.1e-07
XP_011538306 (OMIM: 610585) PREDICTED: rho GTPase- ( 704) 292 56.7 5.1e-07
XP_016866983 (OMIM: 613351) PREDICTED: rho GTPase- ( 635) 291 56.6 5.2e-07
NP_277050 (OMIM: 613351) rho GTPase-activating pro ( 663) 291 56.6 5.4e-07
XP_005267269 (OMIM: 613351) PREDICTED: rho GTPase- ( 713) 291 56.6 5.7e-07
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 290 56.4 5.7e-07
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 290 56.4 5.7e-07
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 290 56.4 5.8e-07
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 290 56.4 6.3e-07
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 290 56.5 6.4e-07
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 290 56.5 6.4e-07
NP_001657 (OMIM: 300023) rho GTPase-activating pro ( 946) 291 56.7 7e-07
NP_001158213 (OMIM: 300023) rho GTPase-activating ( 986) 291 56.7 7.3e-07
XP_016878879 (OMIM: 608293) PREDICTED: rho GTPase- ( 794) 289 56.3 7.6e-07
NP_060524 (OMIM: 608293) rho GTPase-activating pro ( 803) 289 56.3 7.7e-07
XP_011544180 (OMIM: 608293) PREDICTED: rho GTPase- ( 835) 289 56.4 7.9e-07
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395) 282 55.0 9.3e-07
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439) 282 55.1 1e-06
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439) 282 55.1 1e-06
XP_005277572 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 789) 286 55.9 1e-06
NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 286 55.9 1e-06
XP_005277571 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 790) 286 55.9 1e-06
XP_016856330 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 840) 286 55.9 1.1e-06
XP_011507661 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 841) 286 55.9 1.1e-06
XP_016856327 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 286 56.0 1.2e-06
XP_016856328 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 286 56.0 1.2e-06
XP_016856329 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 286 56.0 1.2e-06
XP_011507658 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 986) 286 56.0 1.2e-06
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 283 55.4 1.2e-06
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 283 55.4 1.2e-06
XP_005277568 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1070) 286 56.0 1.3e-06
NP_001164108 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1070) 286 56.0 1.3e-06
NP_056141 (OMIM: 606524) SLIT-ROBO Rho GTPase-acti (1071) 286 56.0 1.3e-06
XP_005277567 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1071) 286 56.0 1.3e-06
XP_011507657 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1083) 286 56.0 1.3e-06
XP_011507656 (OMIM: 606524) PREDICTED: SLIT-ROBO R (1084) 286 56.0 1.3e-06
XP_011544179 (OMIM: 608293) PREDICTED: rho GTPase- ( 836) 284 55.6 1.3e-06
XP_011544178 (OMIM: 608293) PREDICTED: rho GTPase- ( 872) 284 55.6 1.4e-06
>>NP_055598 (OMIM: 610589) rho GTPase-activating protein (1023 aa)
initn: 6690 init1: 6690 opt: 6690 Z-score: 5372.8 bits: 1005.7 E(85289): 0
Smith-Waterman score: 6690; 100.0% identity (100.0% similar) in 1023 aa overlap (1-1023:1-1023)
10 20 30 40 50 60
pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP
970 980 990 1000 1010 1020
pF1KA0 VDL
:::
NP_055 VDL
>>NP_001273408 (OMIM: 610589) rho GTPase-activating prot (834 aa)
initn: 5422 init1: 5422 opt: 5422 Z-score: 4357.6 bits: 817.6 E(85289): 0
Smith-Waterman score: 5422; 100.0% identity (100.0% similar) in 834 aa overlap (190-1023:1-834)
160 170 180 190 200 210
pF1KA0 SCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEK
::::::::::::::::::::::::::::::
NP_001 MDSSNLAVIFAPNLLQTSEGHEKMSSNTEK
10 20 30
220 230 240 250 260 270
pF1KA0 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK
40 50 60 70 80 90
280 290 300 310 320 330
pF1KA0 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS
100 110 120 130 140 150
340 350 360 370 380 390
pF1KA0 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP
160 170 180 190 200 210
400 410 420 430 440 450
pF1KA0 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES
220 230 240 250 260 270
460 470 480 490 500 510
pF1KA0 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM
280 290 300 310 320 330
520 530 540 550 560 570
pF1KA0 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI
340 350 360 370 380 390
580 590 600 610 620 630
pF1KA0 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP
400 410 420 430 440 450
640 650 660 670 680 690
pF1KA0 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH
460 470 480 490 500 510
700 710 720 730 740 750
pF1KA0 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA
520 530 540 550 560 570
760 770 780 790 800 810
pF1KA0 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL
580 590 600 610 620 630
820 830 840 850 860 870
pF1KA0 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA
640 650 660 670 680 690
880 890 900 910 920 930
pF1KA0 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN
700 710 720 730 740 750
940 950 960 970 980 990
pF1KA0 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA
760 770 780 790 800 810
1000 1010 1020
pF1KA0 WYKGSPKHPIGKTQLLPTSKPVDL
::::::::::::::::::::::::
NP_001 WYKGSPKHPIGKTQLLPTSKPVDL
820 830
>>NP_001273409 (OMIM: 610589) rho GTPase-activating prot (834 aa)
initn: 5422 init1: 5422 opt: 5422 Z-score: 4357.6 bits: 817.6 E(85289): 0
Smith-Waterman score: 5422; 100.0% identity (100.0% similar) in 834 aa overlap (190-1023:1-834)
160 170 180 190 200 210
pF1KA0 SCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEK
::::::::::::::::::::::::::::::
NP_001 MDSSNLAVIFAPNLLQTSEGHEKMSSNTEK
10 20 30
220 230 240 250 260 270
pF1KA0 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRLQAAVVQTLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYK
40 50 60 70 80 90
280 290 300 310 320 330
pF1KA0 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKRRQSVGDFVSGALNKFKPNRTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFS
100 110 120 130 140 150
340 350 360 370 380 390
pF1KA0 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKRKSIKHNFNFELLPSNLFNSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVP
160 170 180 190 200 210
400 410 420 430 440 450
pF1KA0 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSKRIAGKKVCRVESGKAGCFSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYES
220 230 240 250 260 270
460 470 480 490 500 510
pF1KA0 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGWRLANQQSLKNRIESVKTGLLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRM
280 290 300 310 320 330
520 530 540 550 560 570
pF1KA0 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWTGPNNSSFQEVDANEASSMVENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNI
340 350 360 370 380 390
580 590 600 610 620 630
pF1KA0 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSPLSGDENNMTKETLVKVQKAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSP
400 410 420 430 440 450
640 650 660 670 680 690
pF1KA0 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EENLFETNDLTIVESKEKYEHHTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEH
460 470 480 490 500 510
700 710 720 730 740 750
pF1KA0 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDIHSNMPKDYLSKQEFSSDEEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEA
520 530 540 550 560 570
760 770 780 790 800 810
pF1KA0 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSFSQQSTCVVTNLSKPRPMRIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSL
580 590 600 610 620 630
820 830 840 850 860 870
pF1KA0 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEPNRIKVKSPLKFQRTPVRQSVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGA
640 650 660 670 680 690
880 890 900 910 920 930
pF1KA0 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSCIESASKDSSVSCIKSGPKEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVN
700 710 720 730 740 750
940 950 960 970 980 990
pF1KA0 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASLRSTTVYKQKILSDGQVKVPLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRA
760 770 780 790 800 810
1000 1010 1020
pF1KA0 WYKGSPKHPIGKTQLLPTSKPVDL
::::::::::::::::::::::::
NP_001 WYKGSPKHPIGKTQLLPTSKPVDL
820 830
>>NP_955389 (OMIM: 610589) rho GTPase-activating protein (501 aa)
initn: 3258 init1: 3258 opt: 3258 Z-score: 2626.2 bits: 496.5 E(85289): 1.5e-139
Smith-Waterman score: 3258; 99.8% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM
:::::::::::::::.
NP_955 LLFSPDVDEKLPKKGTFTYYC
490 500
>>NP_001034930 (OMIM: 616310) rho GTPase-activating prot (267 aa)
initn: 1439 init1: 1439 opt: 1440 Z-score: 1172.7 bits: 226.6 E(85289): 1.4e-58
Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-231:1-226)
10 20 30 40 50 60
pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
::::::::::::::::::::::::::::::::::::.::: .: :::
NP_001 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW
190 200 210 220 230
250 260 270 280 290 300
pF1KA0 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
NP_001 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV
240 250 260
>>XP_016871965 (OMIM: 610585) PREDICTED: rho GTPase-acti (414 aa)
initn: 251 init1: 111 opt: 292 Z-score: 250.0 bits: 56.5 E(85289): 3.4e-07
Smith-Waterman score: 292; 34.9% identity (66.9% similar) in 172 aa overlap (42-205:148-318)
20 30 40 50 60 70
pF1KA0 LQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYG-HIPSFLV
.:: ::: .. : .:: .. .::
XP_016 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLV
120 130 140 150 160 170
80 90 100 110 120
pF1KA0 DACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSAPPCDIAGLLKQFFR
. :... : . ::::: :.. .. :... : :: : :.. .:.::: ..:
XP_016 EQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLR
180 190 200 210 220 230
130 140 150 160 170 180
pF1KA0 ELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRYFFNFLRNVSL
:::::..: .: .:. :: :......:: :. ... . ..:::. .:: .:.
XP_016 ELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQA
240 250 260 270 280 290
190 200 210 220 230 240
pF1KA0 RSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPD
:. :::. .:::..:.::.:.
XP_016 YSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGFWTASRPLQQLFQLKRHTGSCSAGIN
300 310 320 330 340 350
>>XP_016871962 (OMIM: 610585) PREDICTED: rho GTPase-acti (420 aa)
initn: 251 init1: 111 opt: 292 Z-score: 250.0 bits: 56.5 E(85289): 3.5e-07
Smith-Waterman score: 292; 34.9% identity (66.9% similar) in 172 aa overlap (42-205:154-324)
20 30 40 50 60 70
pF1KA0 LQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYG-HIPSFLV
.:: ::: .. : .:: .. .::
XP_016 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLV
130 140 150 160 170 180
80 90 100 110 120
pF1KA0 DACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSAPPCDIAGLLKQFFR
. :... : . ::::: :.. .. :... : :: : :.. .:.::: ..:
XP_016 EQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLR
190 200 210 220 230 240
130 140 150 160 170 180
pF1KA0 ELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRYFFNFLRNVSL
:::::..: .: .:. :: :......:: :. ... . ..:::. .:: .:.
XP_016 ELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQA
250 260 270 280 290 300
190 200 210 220 230 240
pF1KA0 RSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPD
:. :::. .:::..:.::.:.
XP_016 YSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGFWTASRPLQQLFQLKRHTGSCSAGIN
310 320 330 340 350 360
>>XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase-acti (359 aa)
initn: 254 init1: 111 opt: 290 Z-score: 249.3 bits: 56.2 E(85289): 3.8e-07
Smith-Waterman score: 290; 33.3% identity (62.9% similar) in 186 aa overlap (28-205:156-340)
10 20 30 40 50
pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHS
: :: : . ::: .. :
XP_011 PEALLLMASSQRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHH
130 140 150 160 170 180
60 70 80 90 100 110
pF1KA0 AVPEYG-HIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSA
.:: .. .::. :... : . ::::: :.. .. :... : :: : :..
XP_011 ER-KYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTT
190 200 210 220 230 240
120 130 140 150 160
pF1KA0 PPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVH
.:.::: ..::::::..: .: .:. :: :......:: :. ... . .
XP_011 DVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYN
250 260 270 280 290 300
170 180 190 200 210 220
pF1KA0 VLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ
.:::. .:: .:. :. :::. .:::..:.::.:.
XP_011 LLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEESKKGVLT
310 320 330 340 350
230 240 250 260 270 280
pF1KA0 TLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDF
>>XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase-acti (436 aa)
initn: 251 init1: 111 opt: 290 Z-score: 248.1 bits: 56.3 E(85289): 4.4e-07
Smith-Waterman score: 290; 33.3% identity (62.9% similar) in 186 aa overlap (28-205:156-340)
10 20 30 40 50
pF1KA0 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHS
: :: : . ::: .. :
XP_011 PEALLLMASSQRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHH
130 140 150 160 170 180
60 70 80 90 100 110
pF1KA0 AVPEYG-HIPSFLVDACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSA
.:: .. .::. :... : . ::::: :.. .. :... : :: : :..
XP_011 ER-KYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTT
190 200 210 220 230 240
120 130 140 150 160
pF1KA0 PPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVH
.:.::: ..::::::..: .: .:. :: :......:: :. ... . .
XP_011 DVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYN
250 260 270 280 290 300
170 180 190 200 210 220
pF1KA0 VLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQ
.:::. .:: .:. :. :::. .:::..:.::.:.
XP_011 LLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGFWTASRPLQQLF
310 320 330 340 350 360
230 240 250 260 270 280
pF1KA0 TLIDYASDIGRVPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDF
XP_011 QLKRHTGSCSAGINICASCLIFFTYIIIRSDSDVNCDVPCESECLLKKNLRPCVVAHACN
370 380 390 400 410 420
>>NP_001242955 (OMIM: 610585) rho GTPase-activating prot (608 aa)
initn: 300 init1: 120 opt: 292 Z-score: 247.8 bits: 56.7 E(85289): 4.6e-07
Smith-Waterman score: 292; 34.9% identity (66.9% similar) in 172 aa overlap (42-205:58-228)
20 30 40 50 60 70
pF1KA0 LQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVPEYG-HIPSFLV
.:: ::: .. : .:: .. .::
NP_001 ANPEALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHER-KYGPRLAPLLV
30 40 50 60 70 80
80 90 100 110 120
pF1KA0 DACTSL--EDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSAPPCDIAGLLKQFFR
. :... : . ::::: :.. .. :... : :: : :.. .:.::: ..:
NP_001 EQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLR
90 100 110 120 130 140
130 140 150 160 170 180
pF1KA0 ELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLAD---HTVHVLRYFFNFLRNVSL
:::::..: .: .:. :: :......:: :. ... . ..:::. .:: .:.
NP_001 ELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQA
150 160 170 180 190 200
190 200 210 220 230 240
pF1KA0 RSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGRVPD
:. :::. .:::..:.::.:.
NP_001 YSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEG
210 220 230 240 250 260
1023 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:21:08 2016 done: Fri Nov 4 00:21:10 2016
Total Scan time: 14.350 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]