Result of FASTA (omim) for
pF1KA0038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0038, 228 aa
1>>>pF1KA0038 228 - 228 aa - 228 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4961+/-0.000297; mu= 16.3247+/- 0.019
mean_var=132.6977+/-28.433, 0's: 0 Z-trim(120.9): 59 B-trim: 1888 in 1/52
Lambda= 0.111338
statistics sampled from 36714 (36796) to 36714 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.431), width: 16
Scan time: 7.210
The best scores are: opt bits E(85289)
NP_114381 (OMIM: 603431) eukaryotic translation in ( 228) 1568 262.2 5.4e-70
XP_011514859 (OMIM: 603431) PREDICTED: eukaryotic ( 230) 1437 241.1 1.2e-63
NP_071496 (OMIM: 603431) eukaryotic translation in ( 248) 946 162.3 6.7e-40
XP_011514858 (OMIM: 603431) PREDICTED: eukaryotic ( 250) 815 141.3 1.5e-33
NP_001408 (OMIM: 603928) eukaryotic translation in ( 611) 277 55.3 2.6e-07
NP_001287750 (OMIM: 603928) eukaryotic translation ( 616) 277 55.3 2.6e-07
NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] ( 710) 209 44.5 0.00055
NP_001294965 (OMIM: 605133) nuclear cap-binding pr ( 138) 193 41.0 0.0012
NP_031388 (OMIM: 605133) nuclear cap-binding prote ( 156) 193 41.1 0.0013
>>NP_114381 (OMIM: 603431) eukaryotic translation initia (228 aa)
initn: 1568 init1: 1568 opt: 1568 Z-score: 1377.7 bits: 262.2 E(85289): 5.4e-70
Smith-Waterman score: 1568; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228)
10 20 30 40 50 60
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 QDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 QDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREP
130 140 150 160 170 180
190 200 210 220
pF1KA0 TEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 TEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
190 200 210 220
>>XP_011514859 (OMIM: 603431) PREDICTED: eukaryotic tran (230 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1263.9 bits: 241.1 E(85289): 1.2e-63
Smith-Waterman score: 1437; 97.7% identity (99.1% similar) in 215 aa overlap (14-228:16-230)
10 20 30 40 50
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDI
:..: . ::::::::::::::::::::::::::::::::::::::
XP_011 MRSTSMAQPCCPLVISLNGMKRSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 DAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 RKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFR
130 140 150 160 170 180
180 190 200 210 220
pF1KA0 EPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
190 200 210 220 230
>>NP_071496 (OMIM: 603431) eukaryotic translation initia (248 aa)
initn: 956 init1: 933 opt: 946 Z-score: 837.3 bits: 162.3 E(85289): 6.7e-40
Smith-Waterman score: 1518; 91.9% identity (91.9% similar) in 248 aa overlap (1-228:1-248)
10 20 30 40 50 60
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
70 80 90 100 110 120
130 140 150 160
pF1KA0 QDKGGFGFRKGGPDDRG--------------------FRDDFLGGRGGSRPGDRRTGPPM
::::::::::::::::: :::::::::::::::::::::::
NP_071 QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA0 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
190 200 210 220 230 240
pF1KA0 EVVQKEQE
::::::::
NP_071 EVVQKEQE
>>XP_011514858 (OMIM: 603431) PREDICTED: eukaryotic tran (250 aa)
initn: 825 init1: 802 opt: 815 Z-score: 723.5 bits: 141.3 E(85289): 1.5e-33
Smith-Waterman score: 1387; 89.4% identity (90.6% similar) in 235 aa overlap (14-228:16-250)
10 20 30 40 50
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDI
:..: . ::::::::::::::::::::::::::::::::::::::
XP_011 MRSTSMAQPCCPLVISLNGMKRSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 DAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEG
70 80 90 100 110 120
120 130 140 150
pF1KA0 RKQDKGGFGFRKGGPDDRG--------------------FRDDFLGGRGGSRPGDRRTGP
::::::::::::::::::: :::::::::::::::::::::
XP_011 RKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGP
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 PMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARP
190 200 210 220 230 240
220
pF1KA0 REEVVQKEQE
::::::::::
XP_011 REEVVQKEQE
250
>>NP_001408 (OMIM: 603928) eukaryotic translation initia (611 aa)
initn: 370 init1: 139 opt: 277 Z-score: 252.2 bits: 55.3 E(85289): 2.6e-07
Smith-Waterman score: 300; 39.2% identity (65.5% similar) in 148 aa overlap (33-174:87-218)
10 20 30 40 50 60
pF1KA0 DFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIF
...:: :::::..::::..... .: .:
NP_001 SNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFF
60 70 80 90 100 110
70 80 90 100 110 120
pF1KA0 KDLSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQ
. :.: .::: :. .. ...::: :.::...::: ::. . ::.: .:::.:. . :
NP_001 RGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVAD-QAQ
120 130 140 150 160 170
130 140 150 160 170
pF1KA0 DKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDR-----RTGPPMGSRFRDGPPLRGSNMD
:: : :::.: :: .: .:. :. : : : : :: ::..
NP_001 DKD----R----DDRSF------GRDRNRDSDKTDTDWRARPATDS-FDDYPPRRGDDSF
180 190 200 210 220
180 190 200 210 220
pF1KA0 FREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
NP_001 GDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRA
230 240 250 260 270 280
>>NP_001287750 (OMIM: 603928) eukaryotic translation ini (616 aa)
initn: 370 init1: 139 opt: 277 Z-score: 252.2 bits: 55.3 E(85289): 2.6e-07
Smith-Waterman score: 300; 39.2% identity (65.5% similar) in 148 aa overlap (33-174:87-218)
10 20 30 40 50 60
pF1KA0 DFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIF
...:: :::::..::::..... .: .:
NP_001 SNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFF
60 70 80 90 100 110
70 80 90 100 110 120
pF1KA0 KDLSIRSVRLVRD-KDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQ
. :.: .::: :. .. ...::: :.::...::: ::. . ::.: .:::.:. . :
NP_001 RGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVAD-QAQ
120 130 140 150 160 170
130 140 150 160 170
pF1KA0 DKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDR-----RTGPPMGSRFRDGPPLRGSNMD
:: : :::.: :: .: .:. :. : : : : :: ::..
NP_001 DKD----R----DDRSF------GRDRNRDSDKTDTDWRARPATDS-FDDYPPRRGDDSF
180 190 200 210 220
180 190 200 210 220
pF1KA0 FREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
NP_001 GDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRA
230 240 250 260 270 280
>>NP_005372 (OMIM: 164035) nucleolin [Homo sapiens] (710 aa)
initn: 86 init1: 86 opt: 209 Z-score: 192.5 bits: 44.5 E(85289): 0.00055
Smith-Waterman score: 209; 34.6% identity (57.7% similar) in 156 aa overlap (28-178:558-701)
10 20 30 40 50
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGD
.: :.. . ..: : .: .: .:..
NP_005 IEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEET
530 540 550 560 570 580
60 70 80 90 100 110
pF1KA0 IDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFD-EVDS--LKEALTYDGALLGDRSLRVD
. : : :.:. :.: :..: . ::: .:.:. : :. :::. :: . :. .:
NP_005 LKESF-DGSVRA-RIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME-DGEIDGN---KVT
590 600 610 620 630 640
120 130 140 150 160 170
pF1KA0 IAEGRKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSR--FRDGPPLRG
. .. . .:::: : :: : : ::::: : : : .:.: :: : ::
NP_005 LDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGF--GGRGRGG-FGGRGGFRGG---RG
650 660 670 680 690
180 190 200 210 220
pF1KA0 SNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
.. : .
NP_005 GGGDHKPQGKKTKFE
700 710
>>NP_001294965 (OMIM: 605133) nuclear cap-binding protei (138 aa)
initn: 168 init1: 94 opt: 193 Z-score: 186.4 bits: 41.0 E(85289): 0.0012
Smith-Waterman score: 193; 34.1% identity (59.3% similar) in 123 aa overlap (29-148:9-130)
10 20 30 40 50 60
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
:. ..: . : ::::: : :.. .:
NP_001 MVLRKLYAGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYE
10 20 30 40
70 80 90 100 110
pF1KA0 IF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY-DGALLGDRSLRVDIAEG
.: :. .:... . :: :::.::. . ..:. : .:. : :: .:.: :
NP_001 LFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KA0 RKQDKG-GFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDF
:. . : : :.:: .:.:. .::::
NP_001 FKEGRQYGRG-RSGGQVRDEYRQDYDAGRGGYGKLAQNQ
110 120 130
180 190 200 210 220
pF1KA0 REPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
>>NP_031388 (OMIM: 605133) nuclear cap-binding protein s (156 aa)
initn: 168 init1: 94 opt: 193 Z-score: 185.8 bits: 41.1 E(85289): 0.0013
Smith-Waterman score: 193; 34.1% identity (59.3% similar) in 123 aa overlap (29-148:27-148)
10 20 30 40 50 60
pF1KA0 MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
:. ..: . : ::::: : :.. .:
NP_031 MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYE
10 20 30 40 50
70 80 90 100 110
pF1KA0 IF-KDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTY-DGALLGDRSLRVDIAEG
.: :. .:... . :: :::.::. . ..:. : .:. : :: .:.: :
NP_031 LFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KA0 RKQDKG-GFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDF
:. . : : :.:: .:.:. .::::
NP_031 FKEGRQYGRG-RSGGQVRDEYRQDYDAGRGGYGKLAQNQ
120 130 140 150
180 190 200 210 220
pF1KA0 REPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
228 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:27:59 2016 done: Thu Nov 3 19:28:00 2016
Total Scan time: 7.210 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]