Result of FASTA (omim) for
pF1KA0041
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0041, 778 aa
1>>>pF1KA0041 778 - 778 aa - 778 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8522+/-0.000652; mu= 15.4156+/- 0.040
mean_var=344.5053+/-70.716, 0's: 0 Z-trim(113.1): 395 B-trim: 362 in 2/50
Lambda= 0.069100
statistics sampled from 21708 (22263) to 21708 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.261), width: 16
Scan time: 9.110
The best scores are: opt bits E(85289)
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 5108 525.1 4.4e-148
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 5084 522.7 2.3e-147
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 4504 464.9 5.9e-130
XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 4480 462.5 3.1e-129
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 3733 388.1 8.2e-107
XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 3654 380.2 1.9e-104
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 3427 357.5 1.2e-97
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 3427 357.5 1.2e-97
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 3427 357.5 1.2e-97
XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 3129 327.9 1.1e-88
XP_016861535 (OMIM: 607766) PREDICTED: arf-GAP wit ( 848) 3105 325.5 5.8e-88
NP_055531 (OMIM: 607763) arf-GAP with coiled-coil, ( 740) 1872 202.5 5.5e-51
NP_001137250 (OMIM: 616594) arf-GAP with SH3 domai ( 894) 578 73.6 4.1e-12
NP_060177 (OMIM: 616594) arf-GAP with SH3 domain, ( 903) 568 72.6 8.2e-12
XP_016857174 (OMIM: 616594) PREDICTED: arf-GAP wit ( 924) 568 72.6 8.3e-12
XP_016857176 (OMIM: 616594) PREDICTED: arf-GAP wit ( 883) 564 72.2 1.1e-11
XP_016857175 (OMIM: 616594) PREDICTED: arf-GAP wit ( 905) 551 70.9 2.7e-11
XP_011540057 (OMIM: 616594) PREDICTED: arf-GAP wit ( 926) 551 71.0 2.7e-11
XP_016857177 (OMIM: 616594) PREDICTED: arf-GAP wit ( 793) 548 70.5 3.1e-11
XP_016857178 (OMIM: 616594) PREDICTED: arf-GAP wit ( 774) 540 69.7 5.3e-11
XP_016868956 (OMIM: 605953) PREDICTED: arf-GAP wit (1087) 527 68.7 1.5e-10
XP_006716629 (OMIM: 605953) PREDICTED: arf-GAP wit (1075) 513 67.3 4e-10
XP_006716628 (OMIM: 605953) PREDICTED: arf-GAP wit (1076) 513 67.3 4e-10
XP_006716627 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 513 67.3 4.1e-10
XP_011515355 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 513 67.3 4.1e-10
XP_006716626 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 513 67.3 4.1e-10
XP_011515354 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 513 67.3 4.1e-10
XP_005250982 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 513 67.3 4.1e-10
XP_016868958 (OMIM: 605953) PREDICTED: arf-GAP wit (1072) 512 67.2 4.3e-10
XP_016868957 (OMIM: 605953) PREDICTED: arf-GAP wit (1073) 512 67.2 4.3e-10
NP_001234925 (OMIM: 605953) arf-GAP with SH3 domai (1122) 512 67.2 4.4e-10
NP_060952 (OMIM: 605953) arf-GAP with SH3 domain, (1129) 512 67.2 4.4e-10
NP_001128663 (OMIM: 603817) arf-GAP with SH3 domai ( 961) 505 66.4 6.6e-10
NP_003878 (OMIM: 603817) arf-GAP with SH3 domain, (1006) 505 66.4 6.7e-10
XP_011508706 (OMIM: 603817) PREDICTED: arf-GAP wit (1017) 496 65.5 1.3e-09
XP_006711965 (OMIM: 603817) PREDICTED: arf-GAP wit ( 964) 488 64.7 2.1e-09
XP_006711961 (OMIM: 603817) PREDICTED: arf-GAP wit (1009) 488 64.7 2.2e-09
XP_011508710 (OMIM: 603817) PREDICTED: arf-GAP wit ( 959) 482 64.1 3.2e-09
XP_006711964 (OMIM: 603817) PREDICTED: arf-GAP wit ( 970) 482 64.1 3.2e-09
XP_011508709 (OMIM: 603817) PREDICTED: arf-GAP wit ( 975) 482 64.1 3.2e-09
XP_011508708 (OMIM: 603817) PREDICTED: arf-GAP wit ( 978) 482 64.1 3.2e-09
XP_011508705 (OMIM: 603817) PREDICTED: arf-GAP wit (1020) 482 64.2 3.3e-09
XP_011508711 (OMIM: 603817) PREDICTED: arf-GAP wit ( 891) 460 61.9 1.4e-08
XP_011508707 (OMIM: 603817) PREDICTED: arf-GAP wit ( 995) 451 61.0 2.8e-08
XP_005268459 (OMIM: 605370,607785) PREDICTED: rho ( 722) 439 59.6 5.5e-08
NP_001129080 (OMIM: 605370,607785) rho GTPase-acti ( 759) 439 59.6 5.6e-08
NP_055886 (OMIM: 605370,607785) rho GTPase-activat ( 814) 439 59.7 5.8e-08
XP_005263272 (OMIM: 609746) PREDICTED: rho GTPase- ( 735) 423 58.0 1.7e-07
NP_078881 (OMIM: 609746) rho GTPase-activating pro ( 786) 423 58.1 1.7e-07
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 409 56.3 3.5e-07
>>NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ANK (778 aa)
initn: 5108 init1: 5108 opt: 5108 Z-score: 2779.6 bits: 525.1 E(85289): 4.4e-148
Smith-Waterman score: 5108; 100.0% identity (100.0% similar) in 778 aa overlap (1-778:1-778)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 ISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 SKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANA
670 680 690 700 710 720
730 740 750 760 770
pF1KA0 DIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
730 740 750 760 770
>>XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP with co (785 aa)
initn: 3279 init1: 3279 opt: 5084 Z-score: 2766.7 bits: 522.7 E(85289): 2.3e-147
Smith-Waterman score: 5084; 99.1% identity (99.1% similar) in 785 aa overlap (1-778:1-785)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
190 200 210 220 230 240
250 260 270 280 290
pF1KA0 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNR-------RWFSIQN
:::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_006 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 NQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 KAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 CCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGND
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 VINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 SEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 DSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGS
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSI
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 AVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQ
730 740 750 760 770 780
pF1KA0 DSQKF
:::::
XP_006 DSQKF
>>XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP with co (806 aa)
initn: 4499 init1: 4499 opt: 4504 Z-score: 2454.1 bits: 464.9 E(85289): 5.9e-130
Smith-Waterman score: 5042; 96.5% identity (96.5% similar) in 806 aa overlap (1-778:1-806)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHT-------------------------
:::::::::::::::::::::::::::::::::::
XP_016 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTRQGLPLSLRLECRGMIIALLWESSH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 ---ILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRMILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 LFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 EKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 SLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKF
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 VDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDG
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
730 740 750 760 770 780
760 770
pF1KA0 IFRDFSQMASNNPEKLNRFQQDSQKF
::::::::::::::::::::::::::
XP_016 IFRDFSQMASNNPEKLNRFQQDSQKF
790 800
>>XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP with co (813 aa)
initn: 3875 init1: 3279 opt: 4480 Z-score: 2441.1 bits: 462.5 E(85289): 3.1e-129
Smith-Waterman score: 4998; 95.7% identity (95.7% similar) in 810 aa overlap (4-778:4-813)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHT-------------------------
:::::::::::::::::::::::::::::::::::
XP_016 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTRQGLPLSLRLECRGMIIALLWESSH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 ---ILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRMILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
250 260 270 280 290 300
280 290 300 310 320
pF1KA0 LFKRASNAFKTWNR-------RWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIE
:::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 LFKRASNAFKTWNRKKPDHIRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIE
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA0 RRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSL
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA0 DSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLG
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA0 VHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRA
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA0 KYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 QQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 LAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 HTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQP
730 740 750 760 770 780
750 760 770
pF1KA0 GDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
:::::::::::::::::::::::::::::::::
XP_016 GDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
790 800 810
>>XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP with co (813 aa)
initn: 3720 init1: 3655 opt: 3733 Z-score: 2038.7 bits: 388.1 E(85289): 8.2e-107
Smith-Waterman score: 5007; 95.7% identity (95.7% similar) in 810 aa overlap (1-775:1-810)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
490 500 510 520 530 540
550 560
pF1KA0 ISKFGPGDQVRASAQSSV-----------------------------------RSNDSGI
:::::::::::::::::: :::::::
XP_011 ISKFGPGDQVRASAQSSVIAVNSDEARRESLFCPDELDSLFSYFDTSSKLRSIRSNDSGI
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA0 QQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEA
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA0 LAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLG
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA0 HTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQP
730 740 750 760 770 780
750 760 770
pF1KA0 GDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
::::::::::::::::::::::::::::::
XP_011 GDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
790 800 810
>>XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP with co (820 aa)
initn: 3290 init1: 1839 opt: 3654 Z-score: 1996.1 bits: 380.2 E(85289): 1.9e-104
Smith-Waterman score: 4934; 94.8% identity (94.8% similar) in 810 aa overlap (1-768:1-810)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
190 200 210 220 230 240
250 260 270 280 290
pF1KA0 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNR-------RWFSIQN
:::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 NQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 KAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 CCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGND
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 VINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKS
490 500 510 520 530 540
540 550
pF1KA0 SEEKRLSISKFGPGDQVRASAQSSV-----------------------------------
:::::::::::::::::::::::::
XP_011 SEEKRLSISKFGPGDQVRASAQSSVIAVNSDEARRESLFCPDELDSLFSYFDTSSKLRSI
550 560 570 580 590 600
560 570 580 590 600 610
pF1KA0 RSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKN
610 620 630 640 650 660
620 630 640 650 660 670
pF1KA0 LPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KA0 HHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRES
730 740 750 760 770 780
740 750 760 770
pF1KA0 EGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
::::::::::::::::::::::::::::::
XP_011 EGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
790 800 810 820
>>XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP with co (776 aa)
initn: 3008 init1: 1826 opt: 3427 Z-score: 1874.0 bits: 357.5 E(85289): 1.2e-97
Smith-Waterman score: 4701; 94.6% identity (94.6% similar) in 773 aa overlap (45-775:1-773)
20 30 40 50 60 70
pF1KA0 PRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDA
::::::::::::::::::::::::::::::
XP_011 MIDTGKAFCVANKQFMNGIRDLAQYSSNDA
10 20 30
80 90 100 110 120 130
pF1KA0 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
160 170 180 190 200 210
260 270 280 290 300
pF1KA0 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNR-------RWFSIQNNQLVYQKKFKDNPT
:::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQNNQLVYQKKFKDNPT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
460 470 480 490 500 510
550 560 570
pF1KA0 DQVRASAQSSV-----------------------------------RSNDSGIQQSSDDG
::::::::::: ::::::::::::::
XP_011 DQVRASAQSSVIAVNSDEARRESLFCPDELDSLFSYFDTSSKLRSIRSNDSGIQQSSDDG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
580 590 600 610 620 630
640 650 660 670 680 690
pF1KA0 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
640 650 660 670 680 690
700 710 720 730 740 750
pF1KA0 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
700 710 720 730 740 750
760 770
pF1KA0 IFRDFSQMASNNPEKLNRFQQDSQKF
:::::::::::::::::::::::
XP_011 IFRDFSQMASNNPEKLNRFQQDSQKF
760 770
>>XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP with co (776 aa)
initn: 3008 init1: 1826 opt: 3427 Z-score: 1874.0 bits: 357.5 E(85289): 1.2e-97
Smith-Waterman score: 4701; 94.6% identity (94.6% similar) in 773 aa overlap (45-775:1-773)
20 30 40 50 60 70
pF1KA0 PRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDA
::::::::::::::::::::::::::::::
XP_011 MIDTGKAFCVANKQFMNGIRDLAQYSSNDA
10 20 30
80 90 100 110 120 130
pF1KA0 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
160 170 180 190 200 210
260 270 280 290 300
pF1KA0 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNR-------RWFSIQNNQLVYQKKFKDNPT
:::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQNNQLVYQKKFKDNPT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
460 470 480 490 500 510
550 560 570
pF1KA0 DQVRASAQSSV-----------------------------------RSNDSGIQQSSDDG
::::::::::: ::::::::::::::
XP_011 DQVRASAQSSVIAVNSDEARRESLFCPDELDSLFSYFDTSSKLRSIRSNDSGIQQSSDDG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
580 590 600 610 620 630
640 650 660 670 680 690
pF1KA0 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
640 650 660 670 680 690
700 710 720 730 740 750
pF1KA0 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
700 710 720 730 740 750
760 770
pF1KA0 IFRDFSQMASNNPEKLNRFQQDSQKF
:::::::::::::::::::::::
XP_011 IFRDFSQMASNNPEKLNRFQQDSQKF
760 770
>>XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP with co (776 aa)
initn: 3008 init1: 1826 opt: 3427 Z-score: 1874.0 bits: 357.5 E(85289): 1.2e-97
Smith-Waterman score: 4701; 94.6% identity (94.6% similar) in 773 aa overlap (45-775:1-773)
20 30 40 50 60 70
pF1KA0 PRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDA
::::::::::::::::::::::::::::::
XP_011 MIDTGKAFCVANKQFMNGIRDLAQYSSNDA
10 20 30
80 90 100 110 120 130
pF1KA0 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEK
40 50 60 70 80 90
140 150 160 170 180 190
pF1KA0 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KA0 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDD
160 170 180 190 200 210
260 270 280 290 300
pF1KA0 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNR-------RWFSIQNNQLVYQKKFKDNPT
:::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 SKLEYNVDAANGIVMEGYLFKRASNAFKTWNRKKPDHIRRWFSIQNNQLVYQKKFKDNPT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KA0 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREK
280 290 300 310 320 330
370 380 390 400 410 420
pF1KA0 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPG
460 470 480 490 500 510
550 560 570
pF1KA0 DQVRASAQSSV-----------------------------------RSNDSGIQQSSDDG
::::::::::: ::::::::::::::
XP_011 DQVRASAQSSVIAVNSDEARRESLFCPDELDSLFSYFDTSSKLRSIRSNDSGIQQSSDDG
520 530 540 550 560 570
580 590 600 610 620 630
pF1KA0 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADV
580 590 600 610 620 630
640 650 660 670 680 690
pF1KA0 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCL
640 650 660 670 680 690
700 710 720 730 740 750
pF1KA0 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQD
700 710 720 730 740 750
760 770
pF1KA0 IFRDFSQMASNNPEKLNRFQQDSQKF
:::::::::::::::::::::::
XP_011 IFRDFSQMASNNPEKLNRFQQDSQKF
760 770
>>XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP with co (841 aa)
initn: 3111 init1: 3046 opt: 3129 Z-score: 1713.1 bits: 327.9 E(85289): 1.1e-88
Smith-Waterman score: 4941; 92.5% identity (92.5% similar) in 838 aa overlap (1-775:1-838)
10 20 30 40 50 60
pF1KA0 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
10 20 30 40 50 60
70 80 90
pF1KA0 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHT-------------------------
:::::::::::::::::::::::::::::::::::
XP_016 NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTRQGLPLSLRLECRGMIIALLWESSH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 ---ILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRMILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 LFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 VSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 EKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 SLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKF
490 500 510 520 530 540
520 530 540 550
pF1KA0 VDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSV--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVIAVNSDEARRESLF
550 560 570 580 590 600
560 570 580 590
pF1KA0 ---------------------RSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSM
:::::::::::::::::::::::::::::::::::::::
XP_016 CPDELDSLFSYFDTSSKLRSIRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSM
610 620 630 640 650 660
600 610 620 630 640 650
pF1KA0 FLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTC
670 680 690 700 710 720
660 670 680 690 700 710
pF1KA0 EFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEA
730 740 750 760 770 780
720 730 740 750 760 770
pF1KA0 ANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQK
790 800 810 820 830 840
pF1KA0 F
XP_016 F
778 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 17:56:06 2016 done: Wed Nov 2 17:56:07 2016
Total Scan time: 9.110 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]