FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0042, 1648 aa 1>>>pF1KA0042 1648 - 1648 aa - 1648 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0668+/-0.000802; mu= 1.1278+/- 0.049 mean_var=268.8139+/-57.005, 0's: 0 Z-trim(109.4): 332 B-trim: 581 in 3/52 Lambda= 0.078226 statistics sampled from 17201 (17549) to 17201 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.53), E-opt: 0.2 (0.206), width: 16 Scan time: 14.910 The best scores are: opt bits E(85289) NP_055690 (OMIM: 611279,616258) kinesin-like prote (1648) 10602 1212.4 0 XP_011508534 (OMIM: 611279,616258) PREDICTED: kine (1648) 10602 1212.4 0 XP_016858494 (OMIM: 611279,616258) PREDICTED: kine (1648) 10602 1212.4 0 XP_011508533 (OMIM: 611279,616258) PREDICTED: kine (1648) 10602 1212.4 0 XP_016858495 (OMIM: 611279,616258) PREDICTED: kine (1605) 10330 1181.7 0 XP_011508535 (OMIM: 611279,616258) PREDICTED: kine (1620) 10056 1150.8 0 XP_011508537 (OMIM: 611279,616258) PREDICTED: kine (1524) 9477 1085.5 0 XP_016858496 (OMIM: 611279,616258) PREDICTED: kine (1459) 9420 1079.0 0 NP_001292721 (OMIM: 611279,616258) kinesin-like pr (1157) 7458 857.5 0 XP_011508538 (OMIM: 611279,616258) PREDICTED: kine (1157) 7458 857.5 0 XP_016868746 (OMIM: 607350) PREDICTED: kinesin-lik (1490) 1456 180.2 1.2e-43 XP_005273515 (OMIM: 607350) PREDICTED: kinesin-lik (1805) 1456 180.3 1.4e-43 XP_011542760 (OMIM: 607350) PREDICTED: kinesin-lik (1826) 1456 180.3 1.4e-43 NP_056069 (OMIM: 607350) kinesin-like protein KIF1 (1826) 1456 180.3 1.4e-43 XP_011542759 (OMIM: 607350) PREDICTED: kinesin-lik (1847) 1456 180.3 1.4e-43 NP_001099038 (OMIM: 605433) kinesin-like protein K (1749) 1440 178.5 4.6e-43 NP_001099037 (OMIM: 605433) kinesin-like protein K (1757) 1440 178.5 4.6e-43 XP_016866681 (OMIM: 605433) PREDICTED: kinesin-lik (1762) 1440 178.5 4.6e-43 NP_001099036 (OMIM: 605433) kinesin-like protein K (1770) 1440 178.5 4.7e-43 XP_016866679 (OMIM: 605433) PREDICTED: kinesin-lik (1784) 1440 178.5 4.7e-43 XP_016866678 (OMIM: 605433) PREDICTED: kinesin-lik (1792) 1440 178.5 4.7e-43 XP_016866677 (OMIM: 605433) PREDICTED: kinesin-lik (1797) 1440 178.5 4.7e-43 NP_071396 (OMIM: 605433) kinesin-like protein KIF1 (1805) 1440 178.5 4.7e-43 XP_016866680 (OMIM: 605433) PREDICTED: kinesin-lik (1771) 1368 170.4 1.3e-40 XP_011542761 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 1363 169.8 1.9e-40 XP_011542762 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 1363 169.8 1.9e-40 XP_011542763 (OMIM: 607350) PREDICTED: kinesin-lik (1783) 1363 169.8 1.9e-40 NP_055889 (OMIM: 118210,171300,256700,605995) kine (1770) 1225 154.2 9.4e-36 XP_005256481 (OMIM: 603060,611302) PREDICTED: kine (1103) 1217 153.2 1.2e-35 NP_006603 (OMIM: 603060,611302) kinesin-like prote (1103) 1217 153.2 1.2e-35 NP_904325 (OMIM: 118210,171300,256700,605995) kine (1153) 1202 151.5 4.1e-35 NP_004312 (OMIM: 201300,601255,610357,614213,61425 (1690) 1187 149.9 1.8e-34 XP_005247084 (OMIM: 201300,601255,610357,614213,61 (1698) 1187 149.9 1.8e-34 XP_016859879 (OMIM: 201300,601255,610357,614213,61 (1699) 1187 149.9 1.8e-34 XP_006712668 (OMIM: 201300,601255,610357,614213,61 (1782) 1187 149.9 1.8e-34 XP_005247081 (OMIM: 201300,601255,610357,614213,61 (1791) 1187 149.9 1.9e-34 NP_001307634 (OMIM: 201300,601255,610357,614213,61 (1699) 1168 147.8 7.9e-34 NP_001317218 (OMIM: 201300,601255,610357,614213,61 (1708) 1168 147.8 7.9e-34 NP_001317219 (OMIM: 201300,601255,610357,614213,61 (1724) 1168 147.8 7.9e-34 XP_016859877 (OMIM: 201300,601255,610357,614213,61 (1732) 1168 147.8 8e-34 XP_016859876 (OMIM: 201300,601255,610357,614213,61 (1733) 1168 147.8 8e-34 NP_001230937 (OMIM: 201300,601255,610357,614213,61 (1791) 1168 147.8 8.2e-34 XP_016859880 (OMIM: 201300,601255,610357,614213,61 (1799) 1168 147.8 8.2e-34 XP_011509666 (OMIM: 201300,601255,610357,614213,61 (1800) 1168 147.8 8.2e-34 XP_005247079 (OMIM: 201300,601255,610357,614213,61 (1800) 1168 147.8 8.2e-34 XP_016859875 (OMIM: 201300,601255,610357,614213,61 (1816) 1168 147.8 8.3e-34 XP_016859874 (OMIM: 201300,601255,610357,614213,61 (1824) 1168 147.8 8.3e-34 XP_016859873 (OMIM: 201300,601255,610357,614213,61 (1825) 1168 147.8 8.3e-34 XP_016859872 (OMIM: 201300,601255,610357,614213,61 (1825) 1168 147.8 8.3e-34 XP_016866682 (OMIM: 605433) PREDICTED: kinesin-lik (1694) 1150 145.7 3.2e-33 >>NP_055690 (OMIM: 611279,616258) kinesin-like protein K (1648 aa) initn: 10602 init1: 10602 opt: 10602 Z-score: 6482.5 bits: 1212.4 E(85289): 0 Smith-Waterman score: 10602; 100.0% identity (100.0% similar) in 1648 aa overlap (1-1648:1-1648) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1570 1580 1590 1600 1610 1620 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: NP_055 VPKRVYELHGSSPAVSSEECTPSRIQWV 1630 1640 >>XP_011508534 (OMIM: 611279,616258) PREDICTED: kinesin- (1648 aa) initn: 10602 init1: 10602 opt: 10602 Z-score: 6482.5 bits: 1212.4 E(85289): 0 Smith-Waterman score: 10602; 100.0% identity (100.0% similar) in 1648 aa overlap (1-1648:1-1648) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1570 1580 1590 1600 1610 1620 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: XP_011 VPKRVYELHGSSPAVSSEECTPSRIQWV 1630 1640 >>XP_016858494 (OMIM: 611279,616258) PREDICTED: kinesin- (1648 aa) initn: 10602 init1: 10602 opt: 10602 Z-score: 6482.5 bits: 1212.4 E(85289): 0 Smith-Waterman score: 10602; 100.0% identity (100.0% similar) in 1648 aa overlap (1-1648:1-1648) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1570 1580 1590 1600 1610 1620 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: XP_016 VPKRVYELHGSSPAVSSEECTPSRIQWV 1630 1640 >>XP_011508533 (OMIM: 611279,616258) PREDICTED: kinesin- (1648 aa) initn: 10602 init1: 10602 opt: 10602 Z-score: 6482.5 bits: 1212.4 E(85289): 0 Smith-Waterman score: 10602; 100.0% identity (100.0% similar) in 1648 aa overlap (1-1648:1-1648) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1570 1580 1590 1600 1610 1620 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: XP_011 VPKRVYELHGSSPAVSSEECTPSRIQWV 1630 1640 >>XP_016858495 (OMIM: 611279,616258) PREDICTED: kinesin- (1605 aa) initn: 10330 init1: 10330 opt: 10330 Z-score: 6316.8 bits: 1181.7 E(85289): 0 Smith-Waterman score: 10330; 100.0% identity (100.0% similar) in 1605 aa overlap (44-1648:1-1605) 20 30 40 50 60 70 pF1KA0 DILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKVRDINRTYVISASR :::::::::::::::::::::::::::::: XP_016 MSECENDDPLLRSAGKVRDINRTYVISASR 10 20 30 80 90 100 110 120 130 pF1KA0 KTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLTLQRRAKTDSAEKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLTLQRRAKTDSAEKW 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA0 KTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMAD 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA0 KKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGN 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA0 LYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA0 KQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREK 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA0 IEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA0 RAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMS 400 410 420 430 440 450 500 510 520 530 540 550 pF1KA0 FFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGN 460 470 480 490 500 510 560 570 580 590 600 610 pF1KA0 KQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTA 520 530 540 550 560 570 620 630 640 650 660 670 pF1KA0 HTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTA 580 590 600 610 620 630 680 690 700 710 720 730 pF1KA0 MIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNS 640 650 660 670 680 690 740 750 760 770 780 790 pF1KA0 RNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIM 700 710 720 730 740 750 800 810 820 830 840 850 pF1KA0 FQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK 760 770 780 790 800 810 860 870 880 890 900 910 pF1KA0 NFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGR 820 830 840 850 860 870 920 930 940 950 960 970 pF1KA0 DTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK 880 890 900 910 920 930 980 990 1000 1010 1020 1030 pF1KA0 AAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMET 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 pF1KA0 LATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMM 1000 1010 1020 1030 1040 1050 1100 1110 1120 1130 1140 1150 pF1KA0 IQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKEL 1060 1070 1080 1090 1100 1110 1160 1170 1180 1190 1200 1210 pF1KA0 YESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKN 1120 1130 1140 1150 1160 1170 1220 1230 1240 1250 1260 1270 pF1KA0 LHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEERTIADSLINSFLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEERTIADSLINSFLK 1180 1190 1200 1210 1220 1230 1280 1290 1300 1310 1320 1330 pF1KA0 IYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTN 1240 1250 1260 1270 1280 1290 1340 1350 1360 1370 1380 1390 pF1KA0 IARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKG 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KA0 SKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQHELFRQCTKNEVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQHELFRQCTKNEVT 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KA0 KEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKA 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KA0 IEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYESRVTHIVHQELES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYESRVTHIVHQELES 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KA0 LAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKGVPKRVYELHGSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKGVPKRVYELHGSSP 1540 1550 1560 1570 1580 1590 1640 pF1KA0 AVSSEECTPSRIQWV ::::::::::::::: XP_016 AVSSEECTPSRIQWV 1600 >>XP_011508535 (OMIM: 611279,616258) PREDICTED: kinesin- (1620 aa) initn: 10052 init1: 10052 opt: 10056 Z-score: 6149.6 bits: 1150.8 E(85289): 0 Smith-Waterman score: 10355; 98.3% identity (98.3% similar) in 1648 aa overlap (1-1648:1-1620) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAG-- 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT :::::::::::::::::::::::::::::::::: XP_011 --------------------------RLALQRRTTRNKESSLLVSELEDTTEKTAETRLT 60 70 80 90 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1540 1550 1560 1570 1580 1590 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: XP_011 VPKRVYELHGSSPAVSSEECTPSRIQWV 1600 1610 1620 >>XP_011508537 (OMIM: 611279,616258) PREDICTED: kinesin- (1524 aa) initn: 9475 init1: 9475 opt: 9477 Z-score: 5796.9 bits: 1085.5 E(85289): 0 Smith-Waterman score: 9586; 92.5% identity (92.5% similar) in 1648 aa overlap (1-1648:1-1524) 10 20 30 40 50 60 pF1KA0 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSAGKV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSLHSTHNRNNSGDILDIPSSQNSSSLNALTHSSRLKLHLKSDMSECENDDPLLRSA--- 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 RDINRTYVISASRKTADMPLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLT XP_011 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KA0 LQRRAKTDSAEKWKTAEIDSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVP XP_011 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KA0 LDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -DEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPT 60 70 80 90 100 110 250 260 270 280 290 300 pF1KA0 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPTKCTTEHKLTTKCSLPQLKSPA 120 130 140 150 160 170 310 320 330 340 350 360 pF1KA0 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 180 190 200 210 220 230 370 380 390 400 410 420 pF1KA0 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQ 240 250 260 270 280 290 430 440 450 460 470 480 pF1KA0 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVAR 300 310 320 330 340 350 490 500 510 520 530 540 pF1KA0 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIVS 360 370 380 390 400 410 550 560 570 580 590 600 pF1KA0 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRIN 420 430 440 450 460 470 610 620 630 640 650 660 pF1KA0 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTW 480 490 500 510 520 530 670 680 690 700 710 720 pF1KA0 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELK 540 550 560 570 580 590 730 740 750 760 770 780 pF1KA0 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFEQAEKRK 600 610 620 630 640 650 790 800 810 820 830 840 pF1KA0 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQL 660 670 680 690 700 710 850 860 870 880 890 900 pF1KA0 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNH 720 730 740 750 760 770 910 920 930 940 950 960 pF1KA0 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQI 780 790 800 810 820 830 970 980 990 1000 1010 1020 pF1KA0 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQ 840 850 860 870 880 890 1030 1040 1050 1060 1070 1080 pF1KA0 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTFT 900 910 920 930 940 950 1090 1100 1110 1120 1130 1140 pF1KA0 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSSDTSIRVRNLKLGISTFWSL 960 970 980 990 1000 1010 1150 1160 1170 1180 1190 1200 pF1KA0 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRSLMKNRRIS 1020 1030 1040 1050 1060 1070 1210 1220 1230 1240 1250 1260 pF1KA0 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDFFGQSYDEE 1080 1090 1100 1110 1120 1130 1270 1280 1290 1300 1310 1320 pF1KA0 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTACAFEQLVVL 1140 1150 1160 1170 1180 1190 1330 1340 1350 1360 1370 1380 pF1KA0 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQKNAIQIVQQ 1200 1210 1220 1230 1240 1250 1390 1400 1410 1420 1430 1440 pF1KA0 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSGLEKAKELQ 1260 1270 1280 1290 1300 1310 1450 1460 1470 1480 1490 1500 pF1KA0 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQDFKRMVNRA 1320 1330 1340 1350 1360 1370 1510 1520 1530 1540 1550 1560 pF1KA0 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVPSTSVGSYE 1380 1390 1400 1410 1420 1430 1570 1580 1590 1600 1610 1620 pF1KA0 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSGIDGSKNKG 1440 1450 1460 1470 1480 1490 1630 1640 pF1KA0 VPKRVYELHGSSPAVSSEECTPSRIQWV :::::::::::::::::::::::::::: XP_011 VPKRVYELHGSSPAVSSEECTPSRIQWV 1500 1510 1520 >>XP_016858496 (OMIM: 611279,616258) PREDICTED: kinesin- (1459 aa) initn: 9420 init1: 9420 opt: 9420 Z-score: 5762.4 bits: 1079.0 E(85289): 0 Smith-Waterman score: 9420; 100.0% identity (100.0% similar) in 1459 aa overlap (190-1648:1-1459) 160 170 180 190 200 210 pF1KA0 SRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMADKKYKETFSAPSRANENVALKYSSNRP :::::::::::::::::::::::::::::: XP_016 MMADKKYKETFSAPSRANENVALKYSSNRP 10 20 30 220 230 240 250 260 270 pF1KA0 PIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRSIGKEIAKTSNKFGSLEKRTPT 40 50 60 70 80 90 280 290 300 310 320 330 pF1KA0 KCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQVKQRPKSSFLANKQERSAENTILPEEE 100 110 120 130 140 150 340 350 360 370 380 390 pF1KA0 TVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVVQNTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVY 160 170 180 190 200 210 400 410 420 430 440 450 pF1KA0 NFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMG 220 230 240 250 260 270 460 470 480 490 500 510 pF1KA0 FSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSEEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPL 280 290 300 310 320 330 520 530 540 550 560 570 pF1KA0 RVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMT 340 350 360 370 380 390 580 590 600 610 620 630 pF1KA0 QTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISA 400 410 420 430 440 450 640 650 660 670 680 690 pF1KA0 LSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQAR 460 470 480 490 500 510 700 710 720 730 740 750 pF1KA0 LIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIVNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQE 520 530 540 550 560 570 760 770 780 790 800 810 pF1KA0 RDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDMAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYM 580 590 600 610 620 630 820 830 840 850 860 870 pF1KA0 IKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEI 640 650 660 670 680 690 880 890 900 910 920 930 pF1KA0 TVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVLRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQL 700 710 720 730 740 750 940 950 960 970 980 990 pF1KA0 EAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEI 760 770 780 790 800 810 1000 1010 1020 1030 1040 1050 pF1KA0 NNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQ 820 830 840 850 860 870 1060 1070 1080 1090 1100 1110 pF1KA0 KIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKS 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 pF1KA0 SSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITD 940 950 960 970 980 990 1180 1190 1200 1210 1220 1230 pF1KA0 APVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APVSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLP 1000 1010 1020 1030 1040 1050 1240 1250 1260 1270 1280 1290 pF1KA0 GICKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GICKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSS 1060 1070 1080 1090 1100 1110 1300 1310 1320 1330 1340 1350 pF1KA0 DRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRAIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGC 1120 1130 1140 1150 1160 1170 1360 1370 1380 1390 1400 1410 pF1KA0 CLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLDISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCD 1180 1190 1200 1210 1220 1230 1420 1430 1440 1450 1460 1470 pF1KA0 GVGLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVGLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSF 1240 1250 1260 1270 1280 1290 1480 1490 1500 1510 1520 1530 pF1KA0 RRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRQVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIR 1300 1310 1320 1330 1340 1350 1540 1550 1560 1570 1580 1590 pF1KA0 NLASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQ 1360 1370 1380 1390 1400 1410 1600 1610 1620 1630 1640 pF1KA0 NTKEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTKEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV 1420 1430 1440 1450 >>NP_001292721 (OMIM: 611279,616258) kinesin-like protei (1157 aa) initn: 7458 init1: 7458 opt: 7458 Z-score: 4567.1 bits: 857.5 E(85289): 0 Smith-Waterman score: 7458; 100.0% identity (100.0% similar) in 1157 aa overlap (492-1648:1-1157) 470 480 490 500 510 520 pF1KA0 EEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRV :::::::::::::::::::::::::::::: NP_001 MSFFEVYNEKIHDLLVCKDENGQRKQPLRV 10 20 30 530 540 550 560 570 580 pF1KA0 REHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT 40 50 60 70 80 90 590 600 610 620 630 640 pF1KA0 KTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALS 100 110 120 130 140 150 650 660 670 680 690 700 pF1KA0 EQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI 160 170 180 190 200 210 710 720 730 740 750 760 pF1KA0 VNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERD 220 230 240 250 260 270 770 780 790 800 810 820 pF1KA0 MAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIK 280 290 300 310 320 330 830 840 850 860 870 880 pF1KA0 EGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITV 340 350 360 370 380 390 890 900 910 920 930 940 pF1KA0 LRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEA 400 410 420 430 440 450 950 960 970 980 990 1000 pF1KA0 EIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINN 460 470 480 490 500 510 1010 1020 1030 1040 1050 1060 pF1KA0 QKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKI 520 530 540 550 560 570 1070 1080 1090 1100 1110 1120 pF1KA0 AKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSS 580 590 600 610 620 630 1130 1140 1150 1160 1170 1180 pF1KA0 DTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAP 640 650 660 670 680 690 1190 1200 1210 1220 1230 1240 pF1KA0 VSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGI 700 710 720 730 740 750 1250 1260 1270 1280 1290 1300 pF1KA0 CKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDR 760 770 780 790 800 810 1310 1320 1330 1340 1350 1360 pF1KA0 AIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCL 820 830 840 850 860 870 1370 1380 1390 1400 1410 1420 pF1KA0 DISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGV 880 890 900 910 920 930 1430 1440 1450 1460 1470 1480 pF1KA0 GLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRR 940 950 960 970 980 990 1490 1500 1510 1520 1530 1540 pF1KA0 QVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNL 1000 1010 1020 1030 1040 1050 1550 1560 1570 1580 1590 1600 pF1KA0 ASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNT 1060 1070 1080 1090 1100 1110 1610 1620 1630 1640 pF1KA0 KEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV 1120 1130 1140 1150 >>XP_011508538 (OMIM: 611279,616258) PREDICTED: kinesin- (1157 aa) initn: 7458 init1: 7458 opt: 7458 Z-score: 4567.1 bits: 857.5 E(85289): 0 Smith-Waterman score: 7458; 100.0% identity (100.0% similar) in 1157 aa overlap (492-1648:1-1157) 470 480 490 500 510 520 pF1KA0 EEPGIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRV :::::::::::::::::::::::::::::: XP_011 MSFFEVYNEKIHDLLVCKDENGQRKQPLRV 10 20 30 530 540 550 560 570 580 pF1KA0 REHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQT 40 50 60 70 80 90 590 600 610 620 630 640 pF1KA0 KTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALS 100 110 120 130 140 150 650 660 670 680 690 700 pF1KA0 EQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI 160 170 180 190 200 210 710 720 730 740 750 760 pF1KA0 VNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNIAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERD 220 230 240 250 260 270 770 780 790 800 810 820 pF1KA0 MAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEMQRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIK 280 290 300 310 320 330 830 840 850 860 870 880 pF1KA0 EGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHILEITV 340 350 360 370 380 390 890 900 910 920 930 940 pF1KA0 LRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRHGDRVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKNELLMAQRSQLEA 400 410 420 430 440 450 950 960 970 980 990 1000 pF1KA0 EIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQRKKMQEINN 460 470 480 490 500 510 1010 1020 1030 1040 1050 1060 pF1KA0 QKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKI 520 530 540 550 560 570 1070 1080 1090 1100 1110 1120 pF1KA0 AKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTYYVFGRHDISDKSSS 580 590 600 610 620 630 1130 1140 1150 1160 1170 1180 pF1KA0 DTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAP 640 650 660 670 680 690 1190 1200 1210 1220 1230 1240 pF1KA0 VSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSSLSRRRSRSLMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGI 700 710 720 730 740 750 1250 1260 1270 1280 1290 1300 pF1KA0 CKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKELIGSSLDFFGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDR 760 770 780 790 800 810 1310 1320 1330 1340 1350 1360 pF1KA0 AIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIQSLTIQTACAFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCL 820 830 840 850 860 870 1370 1380 1390 1400 1410 1420 pF1KA0 DISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DISSMIKEAQKNAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGV 880 890 900 910 920 930 1430 1440 1450 1460 1470 1480 pF1KA0 GLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGMKILLDSGLEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRR 940 950 960 970 980 990 1490 1500 1510 1520 1530 1540 pF1KA0 QVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVQEENFEYQDFKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNL 1000 1010 1020 1030 1040 1050 1550 1560 1570 1580 1590 1600 pF1KA0 ASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASDFYSDFSVPSTSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNT 1060 1070 1080 1090 1100 1110 1610 1620 1630 1640 pF1KA0 KEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEEHQQSKSSGIDGSKNKGVPKRVYELHGSSPAVSSEECTPSRIQWV 1120 1130 1140 1150 1648 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:03:45 2016 done: Thu Nov 3 09:03:47 2016 Total Scan time: 14.910 Total Display time: 0.940 Function used was FASTA [36.3.4 Apr, 2011]