FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0044, 475 aa 1>>>pF1KA0044 475 - 475 aa - 475 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3352+/-0.000373; mu= 18.8674+/- 0.023 mean_var=81.0364+/-16.436, 0's: 0 Z-trim(114.1): 38 B-trim: 169 in 1/57 Lambda= 0.142474 statistics sampled from 23701 (23739) to 23701 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.278), width: 16 Scan time: 8.430 The best scores are: opt bits E(85289) NP_848701 (OMIM: 601645) serine/threonine-protein ( 485) 3183 664.1 2.4e-190 NP_001155198 (OMIM: 601645) serine/threonine-prote ( 540) 3053 637.4 2.9e-182 XP_005267880 (OMIM: 601645) PREDICTED: serine/thre ( 545) 3053 637.4 2.9e-182 NP_848702 (OMIM: 601645) serine/threonine-protein ( 449) 2891 604.0 2.7e-172 NP_002710 (OMIM: 601645) serine/threonine-protein ( 524) 2887 603.3 5.3e-172 XP_016876912 (OMIM: 601645) PREDICTED: serine/thre ( 479) 2759 576.9 4.1e-164 XP_011535216 (OMIM: 601645) PREDICTED: serine/thre ( 542) 2758 576.8 5.2e-164 NP_001155197 (OMIM: 601645) serine/threonine-prote ( 555) 2758 576.8 5.3e-164 XP_011535221 (OMIM: 601645) PREDICTED: serine/thre ( 508) 2757 576.5 5.7e-164 XP_011535220 (OMIM: 601645) PREDICTED: serine/thre ( 508) 2757 576.5 5.7e-164 XP_005267879 (OMIM: 601645) PREDICTED: serine/thre ( 556) 2757 576.6 6.1e-164 XP_005267877 (OMIM: 601645) PREDICTED: serine/thre ( 579) 2757 576.6 6.3e-164 XP_005267876 (OMIM: 601645) PREDICTED: serine/thre ( 584) 2757 576.6 6.4e-164 XP_005267883 (OMIM: 601645) PREDICTED: serine/thre ( 500) 2751 575.3 1.3e-163 XP_011535223 (OMIM: 601645) PREDICTED: serine/thre ( 518) 2749 574.9 1.8e-163 XP_011535218 (OMIM: 601645) PREDICTED: serine/thre ( 515) 2748 574.7 2.1e-163 XP_011535217 (OMIM: 601645) PREDICTED: serine/thre ( 515) 2748 574.7 2.1e-163 XP_016876913 (OMIM: 601645) PREDICTED: serine/thre ( 410) 2741 573.2 4.8e-163 XP_016876911 (OMIM: 601645) PREDICTED: serine/thre ( 497) 2630 550.4 4.1e-156 XP_005267881 (OMIM: 601645) PREDICTED: serine/thre ( 539) 2629 550.2 5e-156 NP_006236 (OMIM: 601646,616355) serine/threonine-p ( 602) 2509 525.6 1.4e-148 NP_851307 (OMIM: 601646,616355) serine/threonine-p ( 570) 2494 522.5 1.2e-147 NP_851308 (OMIM: 601646,616355) serine/threonine-p ( 496) 2484 520.4 4.4e-147 XP_011535222 (OMIM: 601645) PREDICTED: serine/thre ( 449) 2445 512.4 1.1e-144 XP_005267884 (OMIM: 601645) PREDICTED: serine/thre ( 449) 2445 512.4 1.1e-144 NP_001257405 (OMIM: 601646,616355) serine/threonin ( 451) 2265 475.4 1.5e-133 NP_001269108 (OMIM: 601647) serine/threonine-prote ( 467) 2030 427.1 5.2e-119 NP_006237 (OMIM: 601647) serine/threonine-protein ( 467) 2030 427.1 5.2e-119 NP_006234 (OMIM: 601643) serine/threonine-protein ( 486) 2015 424.0 4.5e-118 NP_001186685 (OMIM: 601643) serine/threonine-prote ( 429) 2003 421.5 2.3e-117 NP_001269109 (OMIM: 601647) serine/threonine-prote ( 462) 1997 420.3 5.7e-117 XP_011543434 (OMIM: 601644) PREDICTED: serine/thre ( 468) 1965 413.7 5.5e-115 NP_006235 (OMIM: 601644) serine/threonine-protein ( 497) 1965 413.7 5.7e-115 NP_001269110 (OMIM: 601647) serine/threonine-prote ( 391) 1907 401.7 1.8e-111 NP_001269111 (OMIM: 601647) serine/threonine-prote ( 391) 1907 401.7 1.8e-111 XP_011543436 (OMIM: 601644) PREDICTED: serine/thre ( 411) 1899 400.1 6e-111 XP_011543435 (OMIM: 601644) PREDICTED: serine/thre ( 411) 1899 400.1 6e-111 >>NP_848701 (OMIM: 601645) serine/threonine-protein phos (485 aa) initn: 3183 init1: 3183 opt: 3183 Z-score: 3538.2 bits: 664.1 E(85289): 2.4e-190 Smith-Waterman score: 3183; 100.0% identity (100.0% similar) in 475 aa overlap (1-475:11-485) 10 20 30 40 50 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA 430 440 450 460 470 480 pF1KA0 SQDGR ::::: NP_848 SQDGR >>NP_001155198 (OMIM: 601645) serine/threonine-protein p (540 aa) initn: 3049 init1: 3049 opt: 3053 Z-score: 3393.2 bits: 637.4 E(85289): 2.9e-182 Smith-Waterman score: 3053; 97.2% identity (98.5% similar) in 471 aa overlap (5-475:72-540) 10 20 30 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQ .:..: .: : ..::::::::::::: NP_001 AVPSTVSAKIKVPVSQPIVKKDKRQNSSRFSASNNRELQK--LPSLKDVPPADQEKLFIQ 50 60 70 80 90 40 50 60 70 80 90 pF1KA0 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF 100 110 120 130 140 150 100 110 120 130 140 150 pF1KA0 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 160 170 180 190 200 210 160 170 180 190 200 210 pF1KA0 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL 220 230 240 250 260 270 220 230 240 250 260 270 pF1KA0 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP 280 290 300 310 320 330 280 290 300 310 320 330 pF1KA0 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE 340 350 360 370 380 390 340 350 360 370 380 390 pF1KA0 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL 400 410 420 430 440 450 400 410 420 430 440 450 pF1KA0 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDP 460 470 480 490 500 510 460 470 pF1KA0 HTKKALEAHCRADELASQDGR ::::::::::::::::::::: NP_001 HTKKALEAHCRADELASQDGR 520 530 540 >>XP_005267880 (OMIM: 601645) PREDICTED: serine/threonin (545 aa) initn: 3049 init1: 3049 opt: 3053 Z-score: 3393.1 bits: 637.4 E(85289): 2.9e-182 Smith-Waterman score: 3053; 97.2% identity (98.5% similar) in 471 aa overlap (5-475:77-545) 10 20 30 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQ .:..: .: : ..::::::::::::: XP_005 AVPSTVSAKIKVPVSQPIVKKDKRQNSSRFSASNNRELQK--LPSLKDVPPADQEKLFIQ 50 60 70 80 90 100 40 50 60 70 80 90 pF1KA0 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF 110 120 130 140 150 160 100 110 120 130 140 150 pF1KA0 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 170 180 190 200 210 220 160 170 180 190 200 210 pF1KA0 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL 230 240 250 260 270 280 220 230 240 250 260 270 pF1KA0 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP 290 300 310 320 330 340 280 290 300 310 320 330 pF1KA0 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE 350 360 370 380 390 400 340 350 360 370 380 390 pF1KA0 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL 410 420 430 440 450 460 400 410 420 430 440 450 pF1KA0 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDP 470 480 490 500 510 520 460 470 pF1KA0 HTKKALEAHCRADELASQDGR ::::::::::::::::::::: XP_005 HTKKALEAHCRADELASQDGR 530 540 >>NP_848702 (OMIM: 601645) serine/threonine-protein phos (449 aa) initn: 2891 init1: 2891 opt: 2891 Z-score: 3214.3 bits: 604.0 E(85289): 2.7e-172 Smith-Waterman score: 2891; 99.5% identity (99.8% similar) in 435 aa overlap (1-435:11-445) 10 20 30 40 50 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_848 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA ::::::::::::::::::::::. : NP_848 LKMKEREEAWVKIENLAKANPQVLKKRIT 430 440 >>NP_002710 (OMIM: 601645) serine/threonine-protein phos (524 aa) initn: 2887 init1: 2887 opt: 2887 Z-score: 3209.0 bits: 603.3 E(85289): 5.3e-172 Smith-Waterman score: 3050; 92.3% identity (92.3% similar) in 507 aa overlap (1-468:11-517) 10 20 30 40 50 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK 370 380 390 400 410 420 420 430 pF1KA0 LKMKEREEAWVKIENLAKANPQ-------------------------------------- :::::::::::::::::::::: NP_002 LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH 430 440 450 460 470 480 440 450 460 470 pF1KA0 -AQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR :::::::::::::::::::::::::::::::::::: NP_002 QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 490 500 510 520 >>XP_016876912 (OMIM: 601645) PREDICTED: serine/threonin (479 aa) initn: 2735 init1: 2735 opt: 2759 Z-score: 3067.3 bits: 576.9 E(85289): 4.1e-164 Smith-Waterman score: 2759; 90.9% identity (93.7% similar) in 460 aa overlap (1-460:11-463) 10 20 30 40 50 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA0 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.. XP_016 DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKHR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA0 LKMKEREEAWVKIENLAKANPQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELA :...: : :.:. . : .: . . :.: .: XP_016 -KIRRRTVL------LHAASPSCLRTPTPRKPWKLTAGPMSWPPRTAASLRGAASGPGPP 430 440 450 460 470 pF1KA0 SQDGR XP_016 VLFRIL >>XP_011535216 (OMIM: 601645) PREDICTED: serine/threonin (542 aa) initn: 2757 init1: 2757 opt: 2758 Z-score: 3065.5 bits: 576.8 E(85289): 5.2e-164 Smith-Waterman score: 2921; 89.9% identity (90.5% similar) in 503 aa overlap (11-468:33-535) 10 20 30 pF1KA0 MVVDAANSNGPFQPVVLLHI------RDVPPADQEKLFIQ :. : .:. : :::::::::::::: XP_011 PTPMGLSSPWSFSIFEGTSPEEPSSPKVPPPLLPELLVLIFGGLQGRDVPPADQEKLFIQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA0 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA0 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA0 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA0 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA0 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA0 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL 370 380 390 400 410 420 400 410 420 430 pF1KA0 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ---------------------- :::::::::::::::::::::::::::::::::::::: XP_011 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPL 430 440 450 460 470 480 440 450 460 470 pF1KA0 -----------------AQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR :::::::::::::::::::::::::::::::::::: XP_011 FEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 490 500 510 520 530 540 >>NP_001155197 (OMIM: 601645) serine/threonine-protein p (555 aa) initn: 2757 init1: 2757 opt: 2758 Z-score: 3065.3 bits: 576.8 E(85289): 5.3e-164 Smith-Waterman score: 2921; 89.9% identity (90.5% similar) in 503 aa overlap (11-468:46-548) 10 20 30 pF1KA0 MVVDAANSNGPFQPVVLLHI------RDVPPADQEKLFIQ :. : .:. : :::::::::::::: NP_001 KSGKSSKEGQDTVESEGTSPEEPSSPKVPPPLLPELLVLIFGGLQGRDVPPADQEKLFIQ 20 30 40 50 60 70 40 50 60 70 80 90 pF1KA0 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMF 80 90 100 110 120 130 100 110 120 130 140 150 pF1KA0 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV 140 150 160 170 180 190 160 170 180 190 200 210 pF1KA0 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAEL 200 210 220 230 240 250 220 230 240 250 260 270 pF1KA0 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEP 260 270 280 290 300 310 280 290 300 310 320 330 pF1KA0 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAE 320 330 340 350 360 370 340 350 360 370 380 390 pF1KA0 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKL 380 390 400 410 420 430 400 410 420 430 pF1KA0 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQ---------------------- :::::::::::::::::::::::::::::::::::::: NP_001 FDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPL 440 450 460 470 480 490 440 450 460 470 pF1KA0 -----------------AQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR :::::::::::::::::::::::::::::::::::: NP_001 FEDVQMLRKTVKDEAHQAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR 500 510 520 530 540 550 >>XP_011535221 (OMIM: 601645) PREDICTED: serine/threonin (508 aa) initn: 2757 init1: 2757 opt: 2757 Z-score: 3064.7 bits: 576.5 E(85289): 5.7e-164 Smith-Waterman score: 2920; 91.6% identity (92.0% similar) in 489 aa overlap (19-468:13-501) 10 20 30 40 50 60 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKR ..:::::::::::::::::::::::::::::::::::::::: XP_011 MFKLHFRHSWQEYFRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKR 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 AALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 WPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 GKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 LLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 ILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIM 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 FPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAW 360 370 380 390 400 410 430 440 pF1KA0 VKIENLAKANPQ---------------------------------------AQKDPKKDR :::::::::::: ::::::::: XP_011 VKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDR 420 430 440 450 460 470 450 460 470 pF1KA0 PLARRKSELPQDPHTKKALEAHCRADELASQDGR ::::::::::::::::::::::::::: XP_011 PLARRKSELPQDPHTKKALEAHCRADELASQDGR 480 490 500 >>XP_011535220 (OMIM: 601645) PREDICTED: serine/threonin (508 aa) initn: 2757 init1: 2757 opt: 2757 Z-score: 3064.7 bits: 576.5 E(85289): 5.7e-164 Smith-Waterman score: 2920; 91.6% identity (92.0% similar) in 489 aa overlap (19-468:13-501) 10 20 30 40 50 60 pF1KA0 MVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKR ..:::::::::::::::::::::::::::::::::::::::: XP_011 MFKLHFRHSWQEYFRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKR 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 AALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 WPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 GKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 LLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 ILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIM 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 FPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAW 360 370 380 390 400 410 430 440 pF1KA0 VKIENLAKANPQ---------------------------------------AQKDPKKDR :::::::::::: ::::::::: XP_011 VKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAHQAQKDPKKDR 420 430 440 450 460 470 450 460 470 pF1KA0 PLARRKSELPQDPHTKKALEAHCRADELASQDGR ::::::::::::::::::::::::::: XP_011 PLARRKSELPQDPHTKKALEAHCRADELASQDGR 480 490 500 475 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:22:46 2016 done: Fri Nov 4 00:22:47 2016 Total Scan time: 8.430 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]